Arjunahills Ingredients & Drug Interactions
by Herbal Hills
What is this page for?
First and foremost: checking Arjunahills against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Arjunahills is a dietary supplement by Herbal Hills with 1 active ingredient. Its ingredients are commonly taken for heart health and circulation, digestive problems (constipation, diarrhea), cholesterol support.Based on those ingredients, 933 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Arjuna bark extract & Arjuna bark powder Blend. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Arjunahills by Herbal Hills
Ask about any prescription or over-the-counter medication and we check it for interactions with Arjunahills by Herbal Hills — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Arjunahills by Herbal Hills
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Arjunahills contains one active ingredient: arjuna bark extract and arjuna bark powder blend. In traditional use, arjuna (Terminalia arjuna) is taken to support heart health and circulation.
The product also contains inactive ingredients—magnesium stearate, silica, and a gelatin capsule—that help hold and deliver the active ingredient.
Does it work?
Not established
The evidence for arjuna's effectiveness in the conditions it's traditionally used for isn't established in the data we hold. Studies looking at its use for obesity, high cholesterol, high blood pressure, and angina all rate as having insufficient reliable evidence to make a clear claim.
That doesn't mean it doesn't work—it means the research backing these uses isn't solid enough yet to say.
How safe is it?
Some data gaps
Arjuna is generally well tolerated in short-term studies, but long-term safety data are limited and quality varies between products. There isn't enough safety information to recommend using this supplement during pregnancy or while breastfeeding, so it's best to avoid it in both cases.
No adverse effects were documented in our data, though that's not a guarantee none have been reported elsewhere.
Meds to double-check
Moderate interaction found
Before taking this product, double-check with your doctor or pharmacist if you take any drugs metabolized by CYP2D6, CYP2C9, or CYP3A4 enzymes (a very common group); blood thinners or antiplatelet drugs like warfarin or aspirin; diabetes medications; chlorzoxazone; or omeprazole. All of these carry Moderate-severity interactions with arjuna.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and some safety-information gaps remain.
Arjunahills is a single-ingredient arjuna supplement often taken for heart and circulation support, but the evidence for those benefits isn't solid. Because arjuna can slow how your liver clears many common medications—and may also increase bleeding risk with blood thinners or lower blood sugar with diabetes drugs—you'll want to check your exact prescriptions and over-the-counter medications with your doctor or pharmacist before starting it.
Avoid it if you're pregnant or breastfeeding.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 25, 2013.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Arjunahills, straight from the product label.
| Brand | Herbal Hills |
|---|---|
| Barcode (UPC) | 8906008264784 |
| Net contents | 60 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Jan 25, 2013 |
| DSLD ID | 16354 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | Qualified Health, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Arjunahills by Herbal Hills, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Arjuna bark extract & Arjuna bark powder Blend | 500 mg | -- |
Other ingredients: Magnesium Stearate, Silica, Gelatin Capsule
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Disclaimer Statement
This product is not intended to diagnose, treat, cure or prevent any disease.
Precautions
Caution : Pregnant or lactating women are advised to consume herbal products under the advice of the Healthcare Practitioner.
Seals/Symbols
HERBALHILLS(R)
GMP Good Manufacturing Practice
ISO 22000:2005 CERTIFIED COMPANY
EXTRACT STANDARDIZED EXTRACT
Brand IP Statement(s)
HERBAL HILLS(R) Back to Nature
Arjunahills(TM)
General Statements
Kit Content
Cardiac Support
Herbal Formulation with Herbal Dietary Supplement for Speedy, Effective & Complete Result
Not intended for sale of individual units. Multipiece package
Suggested/Recommended/Usage/Directions
Direction for use : As a dietary supplement take 1 each of Chologuardhills tablet & Arjunahills capsule twice daily perferably after meals. Take Dudhi Power 1 to 2 tablets preferably after meals or as recommended by the Healthcare Practitioner. For better results it should be taken with warm water.
Formula
12% Tannins, 0.5% Arjunic Acid
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Arjunahills by Herbal Hills label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Arjunahills by Herbal Hills
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Arjuna bark extract & Arjuna bark powder Blend
Interacts with933 drugs
Terminalia is a group of traditional Ayurvedic tree species (most notably Terminalia arjuna) used for heart, digestive, and general wellness purposes....
Arjuna bark extract & Arjuna bark powder Blend monograph & interactionsOther (inactive) ingredients: Magnesium Stearate, Silica, Gelatin Capsule. These complete the product’s ingredient list but are not active constituents.
Arjunahills by Herbal Hills Drug Interactions
HelloPharmacist Interaction Report
Arjunahills by Herbal Hills contains arjuna bark extract and powder, which interacts with a significant number of medications.
The most serious concern is its effect on how your body metabolizes drugs through the cytochrome P450 enzyme system—specifically CYP2D6, CYP2C9, and CYP3A4 substrates. This extract can slow down how your liver clears these drugs, potentially raising their levels in your blood and increasing side effects.
Read the full breakdown — every affected drug type, severity by severity
Beyond that, there are Moderate-severity interactions with blood thinners and antiplatelet drugs (like warfarin and aspirin)—arjuna bark can interfere with how blood clots form, raising bleeding risk. There's also a Moderate interaction with diabetes medications; the extract may lower blood sugar further, increasing the chance of low blood sugar (hypoglycemia).
Two specific drugs are flagged separately: chlorzoxazone (a muscle relaxer) and omeprazole (a heartburn medication)—both can build up to higher levels if you're taking arjuna.
Altogether, these interactions span 934 individual medications. Because the enzyme system it affects is so broadly used, checking your exact medications with our search tool below is important before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Arjunahills?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Arjunahills interact with 933 drugs. Click any drug to see the details.
1 of the 1 ingredient in Arjunahills interact with drugs. Each result below shows which ingredient is responsible. Arjuna bark extract & Arjuna bark powder Blend
Acetaminophen, Chlorpheniramine, PhenylpropanolamineAlumadrine, Conex, Sinadrin Max Strength, Sinulin
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, OpiumHista-Derfule
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, PhenyltoloxamineNorel Plus
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interactionAcetaminophen, Chlorpheniramine, PseudoephedrineAlka-Seltzer PLUS Liquid Gels, Children's Tylenol Cold, Codimal, Comtrex, Extra Strength Tylenol Allergy Sinus, Lorsin +3 more
How Acetaminophen, Chlorpheniramine, Pseudoephedrine interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Acetaminophen, Chlorpheniramine, Pseudoephedrine interactionAcetaminophen, ChlorzoxazoneAcetazone Forte, Extra Strength Tylenol Aches & Strains, Parafon Forte
How Acetaminophen, Chlorzoxazone interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendChlorzoxazone (parafon Forte, Paraflex) Moderate
Interaction Summary
Theoretically, use of Terminalia chebula may increase the risk of adverse effects from chlorzoxazone.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Acetaminophen, Chlorzoxazone interactionAcetaminophen, Chlorzoxazone, CodeineAcetazone Forte C8, Parafon Forte C8
How Acetaminophen, Chlorzoxazone, Codeine interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendChlorzoxazone (parafon Forte, Paraflex), Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia chebula may increase the risk of adverse effects from chlorzoxazone.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Acetaminophen, Chlorzoxazone, Codeine interactionAcetaminophen, CodeineTylenol No.3, Tylenol w/ Codeine
How Acetaminophen, Codeine interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Acetaminophen, Codeine interactionAcetaminophen, Codeine, DoxylamineMersyndol
How Acetaminophen, Codeine, Doxylamine interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Acetaminophen, Codeine, Doxylamine interactionAcetaminophen, Codeine, MethocarbamolAcetaminophen, Codeine, Methocarbamol, Robaxacet 8
How Acetaminophen, Codeine, Methocarbamol interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Acetaminophen, Codeine, Methocarbamol interactionAcetaminophen, DextromethorphanTylenol Cough Ex Strength
How Acetaminophen, Dextromethorphan interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Acetaminophen, Dextromethorphan interactionAcetaminophen, Dextromethorphan, Doxylamine, PseudoephedrineVicks NyQuil
How Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interactionAcetaminophen, Dextromethorphan, Guaifenesin, PhenylephrineConar-A
How Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine interactionAcetaminophen, Dextromethorphan, Guaifenesin, PhenylpropanolamineAnatuss
How Acetaminophen, Dextromethorphan, Guaifenesin, Phenylpropanolamine interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Acetaminophen, Dextromethorphan, Guaifenesin, Phenylpropanolamine interactionAcetaminophen, Dextromethorphan, Guaifenesin, PseudoephedrineRobitussin Cold, Severe Cold, Suphedrine Cold/Cough
How Acetaminophen, Dextromethorphan, Guaifenesin, Pseudoephedrine interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Acetaminophen, Dextromethorphan, Guaifenesin, Pseudoephedrine interactionAcetaminophen, Dextromethorphan, Phenylpropanolamine, PyrilamineTheracaps
How Acetaminophen, Dextromethorphan, Phenylpropanolamine, Pyrilamine interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Acetaminophen, Dextromethorphan, Phenylpropanolamine, Pyrilamine interactionAcetaminophen, Dextromethorphan, PseudoephedrineAlka-Seltzer PLUS Flu Liquid Gels, Non Aspirin Cold Caps, Tylenol Cold, Tylenol Flu Daytime Ex Strength, Tylenol Flu Ex Strength
How Acetaminophen, Dextromethorphan, Pseudoephedrine interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Acetaminophen, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, HydrocodoneAnexsia, Anodynos DHC, Azdone, Co-Gesic, Doucet, Lorcet +9 more
How Acetaminophen, Hydrocodone interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Acetaminophen, Hydrocodone interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendCytochrome P450 2c9 (cyp2c9) Substrates, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2C9 substrates.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Acetaminophen, Ibuprofen interactionAcetaminophen, MeperidineDemerol APAP
How Acetaminophen, Meperidine interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Acetaminophen, Meperidine interactionAcetaminophen, OxycodonePercocet, Roxicet, Tylox, Xartemis XR
How Acetaminophen, Oxycodone interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Acetaminophen, Oxycodone interactionAcetaminophen, Phenylephrine, ChlorpheniramineSuper Cold Tabs
How Acetaminophen, Phenylephrine, Chlorpheniramine interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Acetaminophen, Phenylephrine, Chlorpheniramine interactionAcetaminophen, PropoxypheneDarvocet-N 100, Darvocet-N 50, E-Lor, Wygesic
How Acetaminophen, Propoxyphene interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Acetaminophen, Propoxyphene interactionAcetohexamideDymelor
How Acetohexamide interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Terminalia bellirica or Terminalia chebula with antidiabetes drugs could affect blood sugar control and increase the risk of hypoglycemia.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Acetohexamide interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Terminalia arjuna with anticoagulant or antiplatelet drugs may increase the risk of bleeding in some patients.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Acetylsalicylic Acid interactionAdagrasibKrazati
How Adagrasib interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Adagrasib interactionAerosphere Budesonide, Formoterol Fumarate, GlycopyrrolateBreztri
How Aerosphere Budesonide, Formoterol Fumarate, Glycopyrrolate interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendCytochrome P450 2c9 (cyp2c9) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2C9 substrates.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Aerosphere Budesonide, Formoterol Fumarate, Glycopyrrolate interactionAgomelatineValdoxan
How Agomelatine interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendCytochrome P450 2c9 (cyp2c9) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2C9 substrates.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Agomelatine interactionAlbiglutideTanzeum
How Albiglutide interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Terminalia bellirica or Terminalia chebula with antidiabetes drugs could affect blood sugar control and increase the risk of hypoglycemia.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Albiglutide interactionAlfentanilAlfenta
How Alfentanil interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Alfentanil interactionAlfuzosinUroxatral
How Alfuzosin interacts with Arjunahills — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Extract & Arjuna Bark Powder BlendCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna Bark Extract & Arjuna Bark Powder Blend + Alfuzosin interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Arjunahills with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Arjuna bark extract & Arjuna bark powder Blend
Anticoagulant/Antiplatelet Drugs
Theoretically, concomitant use of Terminalia arjuna with anticoagulant or antiplatelet drugs may increase the risk of bleeding in some patients.
In vitro, Terminalia arjuna bark extract inhibits platelet aggregation, decreases platelet activation, and shows antithrombotic properties.
Antidiabetes Drugs
Theoretically, concomitant use of Terminalia bellirica or Terminalia chebula with antidiabetes drugs could affect blood sugar control and increase the risk of hypoglycemia.
Animal and in vitro research shows that Terminalia bellirica and Terminalia chebula fruit and seed extract have hypoglycemic effects.
Chlorzoxazone (Parafon Forte, Paraflex)
Theoretically, use of Terminalia chebula may increase the risk of adverse effects from chlorzoxazone.
Animal research shows that enteral administration of Terminalia chebula for 15 days prior to administration of chlorzoxazone increases blood levels of chlorzoxazone and decreases chlorzoxazone clearance. It is speculated that Terminalia chebula reduces the metabolism of chlorzoxazone by inhibiting cytochrome P450 2E1.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2C9 substrates.
In vitro research shows that Terminalia arjuna extract inhibits CYP2C9 enzymes and reduces CYP2C9 substrate metabolism.
Cytochrome P450 2D6 (Cyp2D6) Substrates
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
In vitro research shows that Terminalia arjuna extract inhibits CYP2D6 enzymes and reduces CYP2D6 substrate metabolism.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that Terminalia arjuna extract inhibits CYP3A4 enzymes and reduces CYP3A4 substrate metabolism.
Omeprazole (Prilosec)
Theoretically, use of Terminalia chebula may increase the risk of adverse effects from omeprazole.
Animal research shows that enteral administration of Terminalia chebula for 15 days prior to administration of omeprazole increases blood levels of omeprazole and decreases omeprazole clearance. It is speculated that Terminalia chebula reduces the metabolism of omeprazole by inhibiting cytochrome P450 2C19.
Brand information
Manufacturer and brand details for Arjunahills, from the product label.
Herbal Hills
See all Herbal Hills products- Name
- Isha Agro Developers Pvt. Ltd.
- Street Address
- 55-A/B, Lonavala Indl. Co-op. Est. Ltd.
- City
- Nangargaon
- State
- Lonavala
- Phone Number
- 0091 22 2868 6868
- Web Address
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Arjunahills by Herbal Hills: Common Questions
Does Arjunahills by Herbal Hills interact with any medications?
How can one product interact with so many drugs?
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What is arjuna bark used for?
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Arjunahills’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Arjunahills's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 9 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Terminalia 9 references
- Sabu, M. C. and Kuttan, R. Anti-diabetic activity of medicinal plants and its relationship with their antioxidant property. J Ethnopharmacol. 2002;81(2):155-160. PubMed
- Rao, N. K. and Nammi, S. Antidiabetic and renoprotective effects of the chloroform extract of Terminalia chebula Retz. seeds in streptozotocin-induced diabetic rats. BMC.Complement Altern.Med 2006;6:17. PubMed
- Murali, Y. K., Anand, P., Tandon, V., Singh, R., Chandra, R., and Murthy, P. S. Long-term effects of Terminalia chebula Retz. on hyperglycemia and associated hyperlipidemia, tissue glycogen content and in vitro release of insulin in streptozotocin induced
- Senthilkumar, G. P. and Subramanian, S. Evaluation of antioxidant potential of Terminalia chebula fruits studies in streptozotocin-induced diabetic rats. Pharmaceutical Biology (Netherlands) 2007;45:511-518.
- Malik N, Dhawan V, Bahl A, Kaul D. Inihbitory effects of Terminalia arjuna on platelet activation in vitro in healthy subjects and patients with coronary artery disease. Platelets. 2009;20(3):183-1190.
- Varghese A, Savai J, Pandita N, Gaud RS. In vitro modulatory effects of Terminalia arjuna, arjunic acid, arjunetin, and arjungenin on CYP3A4, CYP2D6, and CYP2C9 enzyme activity in human liver microsomes. Toxicology Reports. 2015(2):806-16. PubMed
- Wu G, Dong Z, Dong J, et al. Effects of mongolian medicine Terminalia chebula Retz. on 6 CYP450 enzymes in rats. Int J Clin Exp Pathol 2020;13(12):3128-3138.
- Das A, Naveen J, Sreerama YN, Gnanesh Kumar BS, Baskaran V. Low-glycemic foods with wheat, barley and herbs (Terminalia chebula, Terminalia bellerica and Emblica officinalis) inhibit a-amylase, a-glucosidase and DPP-IV activity in high fat and low dose st
- Eltimamy M, Elshamarka M, Aboelsaad M, Sayed M, Moawad H. Effects of alcoholic extract of Terminalia Chebula dried fruit on blood biochemical profile in diabetic rats. J Diabetes Metab Disord 2022;21(1):159-170. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC