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Dietary supplement

Detoxhills Ingredients & Drug Interactions

by Herbal Hills

Detoxhills label
See full label image
Tablet Or Pill Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Detoxhills against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Detoxhills is a dietary supplement by Herbal Hills with 6 active ingredients. Its ingredients are commonly taken for digestive upset, respiratory and cough complaints, boosting absorption of other supplements.Based on those ingredients, 896 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bhavana Dravya: Pippali. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Detoxhills by Herbal Hills

Ask about any prescription or over-the-counter medication and we check it for interactions with Detoxhills by Herbal Hills — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Detoxhills by Herbal Hills

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 6 active ingredients.
  • “Proprietary Herbal Blend” is a proprietary blend — the label gives one combined amount (550 mg) without saying how much of each component you get.

Detoxhills is a six-ingredient herbal formula. Most of the actives are traditional Ayurvedic botanicals and blends — Haritaki, Bahava magaj, Nishottar Ghana, Triphala Churna (a classic three-herb combination), and Trikatu Ghana (another traditional blend).

The formula also contains Pippali (Indian long pepper), which is listed as a bhavana dravya, or processing agent, in Ayurvedic medicine. The tablet also contains inactive ingredients like xanthan gum, maize starch, silicon dioxide, and magnesium stearate.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Indian Long Pepper's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: enhance detoxification and digestive health.
  • We looked for evidence on: Dyspepsia, Liver disease, detoxification, acidity relief, gas reduction.
  • The closest evidence on file: Indian Long Pepper is rated "Insufficient Reliable Evidence To Rate" for Liver disease (Natural Medicines).
  • Also on file: Indian Long Pepper is rated "Insufficient Reliable Evidence To Rate" for Dyspepsia.

The evidence for Pippali isn't established for the conditions Detoxhills appears to target — we have insufficient reliable evidence to rate it for bronchitis, asthma, cancer, cardiovascular disease, or liver disease. We don't hold effectiveness data for the other five ingredients, so we can't speak to how well this formula works as a whole.

The evidence, ingredient by ingredient Indian Long Pepper

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Pippali is likely fine in food amounts, but concentrated supplement doses lack strong safety data. The piperine in it can affect how your body absorbs other substances, so this is an ingredient to be cautious about, especially if you're on other medications.

During pregnancy, medicinal amounts of Pippali aren't well studied and are traditionally discouraged — avoid it at that dose. There isn't enough safety information for medicinal amounts while breastfeeding, so avoid it then too.

We don't have safety data on file for the other ingredients.

Side effects, ingredient by ingredient Indian Long Pepper

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Indian Long Pepper.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications.
  • For scale: 897 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Detoxhills, double-check with your pharmacist if you take propranolol (Inderal) or any other heart or blood pressure medication, anticoagulants or antiplatelet drugs (blood thinners or aspirin-type drugs), diabetes medications, theophylline (for asthma or COPD), pentobarbital (a sedative), or cyclosporine (an immunosuppressant). All of these can be affected by Pippali.

Additionally, if you take any medication metabolized by your liver, run it through the interaction checker below — Pippali inhibits major liver pathways that process hundreds of drugs.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and some safety-information gaps remain.

This is an Ayurvedic herbal blend that we could only partially check for drug interactions. If you take prescription medications — especially heart medications, blood thinners, diabetes drugs, or anything metabolized by your liver — talk to your pharmacist before starting it.

Pippali's interaction profile is the main concern here. Pregnant or breastfeeding?

Skip the medicinal dose and ask your doctor.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 23, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Detoxhills, straight from the product label.

Brand Herbal Hills
Barcode (UPC) 8906068411166
Net contents 900 Tablet(s)
Market status On market
Date entered into DSLD Jun 23, 2017
DSLD ID 75000
Product type Botanical
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Halal
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Detoxhills by Herbal Hills, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
UPC/BARCODE
8906068411166
IngredientAmount% DV
Proprietary Herbal Blend550 mg--
Haritaki0 NP--
Bahava magaj0 NP--
Nishottar Ghana0 NP--
Triphala Churna0 NP--
Trikatu Ghana0 NP--
Bhavana Dravya: Pippali0 NP--

Other ingredients: Xanthan Gum, Maize Starch, Silicon Dioxide, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Dietary Supplement

General Statements

Suggested Use: ~ May enhance detoxification of undesirable compounds ~ Helps to reduce acidity & gas ~ Supports maintenance of digestive health

Mfg. Lic. No.: PD/AYU/002/10

(An ISO 22000:2005 Certified Company)

Back to nature

Natural detox formula body cleanse

Formulation with unrevealed secrets of natural bioenhancer

~ Pure ~ Natural ~ Effective

Colour Name: Yellow Iron Oxide.

Seals/Symbols

JAS-ANZ ICS ISO 22000:2005 Reg. No.: RH91/7301

GMP Good Manufacturing Practice

Halal India www.halalindia.com

Storage

Store in a cool dry place away from direct sunlight.

Precautions

Keep out of reach of children.

Do not use if inner seal is broken or missing.

Caution: Pregnant or lactating women are advised to consume herbal products under the advice of the healthcare practitioner.

Suggested/Recommended/Usage/Directions

Direction For Use: As a dietary supplement take one tablet once at bedtime. For better results it should be taken with warm water.

FDA Disclaimer Statement

These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Detoxhills by Herbal Hills label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Detoxhills label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Detoxhills by Herbal Hills

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Herbal Blend

550 mg per serving
  • › Haritaki
  • › Bahava magaj
  • › Nishottar Ghana
  • › Triphala Churna
  • › Trikatu Ghana
  • › Bhavana Dravya: Pippali

Other (inactive) ingredients: Xanthan Gum, Maize Starch, Silicon Dioxide, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Detoxhills by Herbal Hills Drug Interactions

Want to check YOUR meds against Detoxhills?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
896Drugs
893 Moderate 3 Minor

Ingredients driving the most interactions

Bhavana Dravya: Pippali 896

Individual Drug Interactions

The ingredients in Detoxhills interact with 896 drugs. Click any drug to see the details.

1 of the 6 ingredients in Detoxhills interact with drugs. Each result below shows which ingredient is responsible. Bhavana Dravya: Pippali

Each ingredient & the kinds of drugs it affects

For each ingredient in Detoxhills with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Bhavana Dravya: Pippali14 drug types · 896 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, Indian long pepper might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
In vitro research shows that Indian long pepper extract inhibits platelet aggregation.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, Indian long pepper might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research shows that piperine, a constituent of Indian long pepper, can reduce blood glucose levels. Monitor blood glucose levels closely. Dose adjustments might be necessary.

Likelihood Possible Evidence D
Cyclosporine (Neoral, Sandimmune)

Theoretically, Indian long pepper might increase the effects and adverse effects of cyclosporine.
In vitro research shows that piperine, a constituent of Indian long pepper, increases the bioavailability of cyclosporine.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, Indian long pepper might increase the effects and adverse effects of CYP3A4 substrates.
In vitro research shows that piperine, a constituent of Indian long pepper, inhibits CYP3A4.

Likelihood Possible Evidence D
Nevirapine (Viramune)

Theoretically, Indian long pepper might increase blood levels of nevirapine.
A small pharmacokinetic study shows that piperine, a constituent of Indian long pepper, increases the plasma concentration and systemic exposure of nevirapine. However, no adverse effects were associated with the elevated plasma levels of nevirapine.

Likelihood Probable Evidence B
P-Glycoprotein Substrates

Theoretically, Indian long pepper might increase levels of P-glycoprotein substrates.
In vitro research shows that piperine, a constituent of Indian long pepper, can inhibit P-glycoprotein.

Likelihood Possible Evidence D
Pentobarbital (Nembutal)

Theoretically, Indian long pepper might increase the sedative effects of pentobarbital.
Animal research shows that piperine, a constituent of Indian long pepper, can increase pentobarbitone-induced sleeping time.

Likelihood Possible Evidence D
Phenytoin (Dilantin)

Theoretically, Indian long pepper might increase blood levels of phenytoin.
A small pharmacokinetic study shows that piperine, a constituent of Indian long pepper, increases phenytoin serum levels and slows its elimination.

Likelihood Possible Evidence B
Propranolol (Inderal)

Theoretically, Indian long pepper might increase blood levels of propranolol.
A small pharmacokinetic study shows that piperine, a constituent of Indian long pepper, accelerates absorption and increases serum concentrations of propranolol.

Likelihood Possible Evidence B
Rifampin (Rifadin)

Theoretically, Indian long pepper might increase blood levels of rifampin.
Piperine, a constituent of Indian long pepper, seems to increase absorption and serum levels of rifampin.

Likelihood Possible Evidence D
Theophylline

Indian long pepper might increase blood levels of theophylline.
A small pharmacokinetic study shows that piperine, a constituent of Indian long pepper, increases serum concentrations and slows elimination of theophylline.

Likelihood Possible Evidence B
Amoxicillin (Amoxil, Trimox)

Theoretically, Indian long pepper might increase the effects and adverse effects of amoxicillin.
Evidence from animal research shows that piperine, a constituent of Indian long pepper, increases the plasma levels of amoxicillin when taken concomitantly.

Likelihood Possible Evidence D
Carbamazepine (Tegretol)

Theoretically, Indian long pepper might increase blood levels of carbamazepine.
A small pharmacokinetic study in patients taking carbamazepine 300 mg or 500 mg twice daily shows that a single 20 mg dose of purified piperine, which is a constituent of Indian long pepper, increases carbamazepine levels. Piperine may increase absorption by increasing blood flow to the GI tract, increasing the surface area of the small intestine, or by cytochrome P450 3A4 (CYP3A4) inhibition in the gut wall. Absorption was significantly increased by 7-10 mcg/mL/hour. The time to eliminate carbamazepine was also increased by 4-8 hours. Although carbamazepine levels were increased, this did not appear to increase side effects.

Likelihood Possible Evidence B
Cefotaxime (Claforan)

Theoretically, Indian long pepper might increase the effects and adverse effects of cefotaxime.
Animal research shows that piperine, a constituent of Indian long pepper, increases the plasma levels of cefotaxime when taken concomitantly.

Likelihood Possible Evidence D
Bhavana Dravya: Pippali full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Detoxhills, from the product label.

Herbal Hills

See all Herbal Hills products
Name
Isha Agro Developers Pvt. Ltd.
Street Address
55-A/B, Lonavala Co-op. Indl. Est. Ltd.
City
Nangargaon, Lonavala, Taluka-Maval, Dist. Pune,
State
Maharashtra
ZipCode
410401
Web Address
0091 22 2868 6868
Pharmacist Counseling Corner

Detoxhills by Herbal Hills: Common Questions

Does Detoxhills by Herbal Hills interact with any medications?
Yes. Based on its ingredients, Detoxhills has a known interaction with 896 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Detoxhills contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Detoxhills if I'm pregnant or breastfeeding?
No — medicinal amounts of Pippali, one of this product's ingredients, are not well studied in pregnancy and are traditionally discouraged. During breastfeeding, there isn't enough safety information for medicinal doses. Talk with your doctor or pharmacist about whether this product is right for you.
What does Triphala Churna do in this formula?
Triphala Churna is a traditional Ayurvedic blend of three herbs, but we don't have effectiveness data on file for the conditions this product targets. It's included as part of the traditional formula, but evidence for how well it works in Detoxhills isn't established.
Is Pippali the same as black pepper?
No — Pippali is Indian long pepper, a different plant from black pepper, though both contain piperine. Pippali is used in Ayurvedic medicine and here acts as a processing agent, but it can interact with quite a few medications.
Why can't you check the other ingredients for interactions?
We simply don't have interaction data on file for Haritaki, Bahava magaj, Nishottar Ghana, Triphala Churna, or Trikatu Ghana. That doesn't mean they don't interact — just that we haven't checked them. If any of them are important to you, ask your pharmacist.
Does this product have fillers or additives?
Yes — the tablet contains xanthan gum, maize starch, silicon dioxide, and magnesium stearate to bind and stabilize the formula.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Detoxhills is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Detoxhills label
Go deeper

The Full Monographs Behind Detoxhills’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Indian Long Pepper

Interacts with 896 drugs

Indian long pepper (pippali) is a spice long used in Ayurvedic medicine and is best known for its piperine content, which may increase how well the body absorbs certain other substances. Mod...

Read the full Indian Long Pepper monograph →
Sources

Sources & How We Checked

Detoxhills's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Indian Long Pepper 12 references
  1. Bano G, Amla V, Raina RK, et al. The effect of piperine on pharmacokinetics of phenytoin in healthy volunteers. Planta Med 1987;53:568-9. PubMed
  2. Bano G, et al. Effect of piperine on bioavailability and pharmacokinetics of propranolol and theophylline in healthy volunteers. Eur J Clin Pharmacol 1991;41;615-7. PubMed
  3. Bhardwaj RK, Glaeser H, Becquemont L, et al. Piperine, a major constituent of black pepper, inhibits human P-glycoprotein and CYP3A4. J Pharmacol Exp Ther 2002;302:645-50. PubMed
  4. Pattanaik S, Hota D, Prabhakar S, et al. Pharmacokinetic interaction of a single dose of piperine with steady-state carbamazepine in epilepsy patients. Phytother Res 2009;23:1281-6.
  5. Kasibhatta, R. and Naidu, M. U. Influence of piperine on the pharmacokinetics of nevirapine under fasting conditions: a randomised, crossover, placebo-controlled study. Drugs R.D. 2007;8(6):383-391. PubMed
  6. Mujumdar, A. M., Dhuley, J. N., Deshmukh, V. K., Raman, P. H., Thorat, S. L., and Naik, S. R. Effect of piperine on pentobarbitone induced hypnosis in rats. Indian J Exp.Biol. 1990;28(5):486-487.
  7. Panda, S. and Kar, A. Piperine lowers the serum concentrations of thyroid hormones, glucose and hepatic 5'D activity in adult male mice. Horm.Metab Res. 2003;35(9):523-526. PubMed
  8. Hiwale, A. R., Dhuley, J. N., and Naik, S. R. Effect of co-administration of piperine on pharmacokinetics of beta-lactam antibiotics in rats. Indian J Exp.Biol. 2002;40(3):277-281.
  9. Han, Y., Chin Tan, T. M., and Lim, L. Y. In vitro and in vivo evaluation of the effects of piperine on P-gp function and expression. Toxicol.Appl.Pharmacol. 8-1-2008;230(3):283-289. PubMed
  10. Sharma, P., Varma, M. V., Chawla, H. P., and Panchagnula, R. In situ and in vivo efficacy of peroral absorption enhancers in rats and correlation to in vitro mechanistic studies. Farmaco 2005;60(11-12):874-883. PubMed
  11. Zutshi, R. K., Singh, R., Zutshi, U., Johri, R. K., and Atal, C. K. Influence of piperine on rifampicin blood levels in patients of pulmonary tuberculosis. J Assoc.Physicians India 1985;33(3):223-224.
  12. Yadav V, Krishnan A, Vohora D. A systematic review on Piper longum L.: Bridging traditional knowledge and pharmacological evidence for future translational research. J Ethnopharmacol. 2020;247:112255. PubMed

See these in context on the Indian Long Pepper monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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