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Dietary supplement

Ashitaba 20:1 Concentrated Extract Ingredients & Drug Interactions

by Samsara Herbs

Ashitaba 20:1 Concentrated Extract label
See full label image
Powder Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Ashitaba 20:1 Concentrated Extract against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Ashitaba 20:1 Concentrated Extract is a dietary supplement by Samsara Herbs with 1 active ingredient. Its ingredients are commonly taken for general wellness and longevity, antioxidant support, heart and cholesterol health.Based on those ingredients, 186 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Ashitaba. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Ashitaba 20:1 Concentrated Extract by Samsara Herbs

Ask about any prescription or over-the-counter medication and we check it for interactions with Ashitaba 20:1 Concentrated Extract by Samsara Herbs — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Ashitaba 20:1 Concentrated Extract by Samsara Herbs

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: ashitaba extract in a concentrated 20:1 form, meaning the powder is made from 20 parts of the plant reduced to 1 part. There are no inactive ingredients listed.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Ashitaba product and its label doesn't state a use — see Ashitaba's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The data we hold shows only one effectiveness claim for ashitaba: alcohol-related liver disease. That evidence rating is insufficient — meaning we don't have enough reliable studies to know whether it actually works for that condition.

If you're considering this supplement for another use, the evidence we have on file doesn't cover it.

The evidence, ingredient by ingredient Ashitaba

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Ashitaba used as a food has been generally well tolerated, but concentrated supplement safety hasn't been studied well enough to confirm it's safe across the board. The safety data advises against using this concentrated supplement during pregnancy and while breastfeeding — there isn't enough information to know whether it could affect you or your baby, so it's best to skip it during those times.

Side effects, ingredient by ingredient Ashitaba

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Ashitaba.
  • The most serious interaction on file is rated Moderate.
  • For scale: 186 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, double-check any medications that are broken down by the liver enzyme CYP1A2 (drug substrates). These are processed more slowly when ashitaba is present, raising the risk of side effects.

Use the medication search tool on this page to see if any of your drugs fall into that group.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and some safety-information gaps remain.

If you're not pregnant or breastfeeding and you want to try ashitaba as a supplement, check your medications first — especially anything your liver processes. Bring the interaction checker results to your pharmacist, since we know this product *could* slow how your body clears certain drugs, even though it hasn't been proven to cause problems in real patients yet.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Ashitaba 20:1 Concentrated Extract, straight from the product label.

Brand Samsara Herbs
Barcode (UPC) X000WDRJ4V
Net contents 16 Ounce(s); 1 Pound(s); 454 Gram(s)
Market status On market
Date entered into DSLD Nov 22, 2024
DSLD ID 319934
Product type Botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Ashitaba 20:1 Concentrated Extract by Samsara Herbs, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2680 Milligram(s)
Maximum serving Sizes:
2680 Milligram(s)
Servings per container
171
UPC/BARCODE
X000WDRJ4V
IngredientAmount% DV
Ashitaba2680 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Full Spectrum

Full Spectrum herbal extracts are made by concentrating the herb into an extract form, while maintaining all of its original compounds. The ideal choice for those wanting a more potent version of a complete herbal powder.

Proudly Manufactured in Utah, USA, in a 3rd party audited cGMP facility for Samsara Herbs Inc.

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

GMP Good Manufacturing Practice USA Tested 3rd party USA tested

General Statements

About us At Samsara Herbs, we believe that all positive change in the world must first begin with positive change from within. We invite you to tap into your own infinite power through the use of our potent herbal extracts! We seek out only quality herbs from our trusted sources from around the world for use in our herbal extracts. Samsara Herbs, dedicated to empowering your life force!

Formula

Description Ashitaba is a native to Hachijo Jima, a small volcanic island off the coast of Japan. Young Ashitaba leaves and stems, as well as the plant’s roots, have been an integral part of the diet of the island's residents, who are known to have one of the longest life expectancies on the plant. These residents have referred to Ashitaba as the "longevity herb.”

Suggested/Recommended/Usage/Directions

Our water soluble herbal extracts are best mixed in juice or a smoothie, although mixing in water is perfectly fine if you can tolerate the taste.

Suggested Use: Take 1 Scoop 1-3 times per day or as recommended by your health care professional.

Storage

Storage Cool dry place, out of direct sunlight.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Precautions

Caution: If you have a medical condition, are pregnant or taking medications, consult your hearth care professional before using this product.

Keep out of reach of children.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Ashitaba 20:1 Concentrated Extract by Samsara Herbs label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Ashitaba 20:1 Concentrated Extract label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Ashitaba 20:1 Concentrated Extract by Samsara Herbs

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2680 Milligram(s) Dosage formPowder Servings per container171 Amounts shown are per serving.

Ashitaba

Interacts with
186 drugs
2680 mg per serving

Ashitaba is a leafy plant from Japan that is eaten as a vegetable and taken as a supplement for general health, antioxidant, and heart benefits. Most...

Ashitaba monograph & interactions
Interaction report

Ashitaba 20:1 Concentrated Extract by Samsara Herbs Drug Interactions

Want to check YOUR meds against Ashitaba 20:1 Concentrated Extract?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
186Drugs
186 Moderate

Ingredients driving the most interactions

Ashitaba 186

Individual Drug Interactions

The ingredients in Ashitaba 20:1 Concentrated Extract interact with 186 drugs. Click any drug to see the details.

1 of the 1 ingredient in Ashitaba 20:1 Concentrated Extract interact with drugs. Each result below shows which ingredient is responsible. Ashitaba

Each ingredient & the kinds of drugs it affects

For each ingredient in Ashitaba 20:1 Concentrated Extract with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Ashitaba1 drug type · 186 drugs

Cytochrome P450 1A2 (Cyp1A2) Substrates

In vitro research shows that ashitaba extract inhibits cytochrome P450 (CYP) 1A2. Theoretically, concomitant use of ashitaba with CYP1A2 substrates might decrease the clearance of these substrates and increase the risk for adverse effects. However, this interaction has yet to be reported in humans. Until more is known, use with caution.

Likelihood Possible Evidence D
Ashitaba full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Ashitaba 20:1 Concentrated Extract, from the product label.

Samsara Herbs

See all Samsara Herbs products
Name
Samsara Herbs Inc.
Street Address
PO Box 160215
City
Clearfield
State
Utah
ZipCode
84016
Phone Number
1-844-972-6727
Web Address
www.SamsaraHerbs.com
Pharmacist Counseling Corner

Ashitaba 20:1 Concentrated Extract by Samsara Herbs: Common Questions

Does Ashitaba 20:1 Concentrated Extract by Samsara Herbs interact with any medications?
Yes. Based on its ingredients, Ashitaba 20:1 Concentrated Extract has a known interaction with 186 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Ashitaba 20:1 Concentrated Extract contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is ashitaba safe while I'm pregnant or breastfeeding?
The safety data advises against this concentrated supplement during pregnancy and breastfeeding because there isn't enough information to know whether it's safe for you or your baby. Talk with your pharmacist or doctor about your options if you're considering it.
What is ashitaba supposed to do?
The only effectiveness claim we have data for is alcohol-related liver disease, but that evidence is too limited to say whether ashitaba actually works for it. We don't have reliable evidence for other uses.
Has ashitaba extract been studied for safety?
Ashitaba used as food has been generally well tolerated, but concentrated supplement safety hasn't been well studied. That's why the pregnancy and breastfeeding cautions are in place — we just don't have enough data yet.
Can ashitaba really interact with 186 medications?
Ashitaba slows down a liver enzyme (CYP1A2) that breaks down a large number of different drugs. That's why 186 medications could theoretically be affected. The important thing is to check your specific medications using the tool on this page, not to assume all 186 apply to you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Ashitaba 20:1 Concentrated Extract is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Ashitaba 20:1 Concentrated Extract label
Go deeper

The Full Monographs Behind Ashitaba 20:1 Concentrated Extract’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Ashitaba

Interacts with 186 drugs

Ashitaba is a leafy plant from Japan that is eaten as a vegetable and taken as a supplement for general health, antioxidant, and heart benefits. Most of the supporting research comes from la...

Read the full Ashitaba monograph →
Sources

Sources & How We Checked

Ashitaba 20:1 Concentrated Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Ashitaba 2 references
  1. Kwon D, Yoon S, Carter O, Bailey GS, Dashwood RH. Antioxidant and antigenotoxic activities of Angelica keiskei, Oenanthe javanica and Brassica oleracea in the Salmonella mutagenicity assay and in HCT116 human colon cancer cells. Biofactors. 2006;26(4):231
  2. Noh HM, Ahn EM, Yun JM, Cho BL, Paek YJ. Angelica keiskei Koidzumi extracts improve some markers of liver function in habitual alcohol drinkers: a randomized double-blind clinical trial. J Med Food. 2015;18(2):166-72.

See these in context on the Ashitaba monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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