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Dietary supplement

Astaxanthin Capsules Ingredients & Drug Interactions

by Higher Nature Aeterna Gold

Astaxanthin Capsules label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Astaxanthin Capsules against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Astaxanthin Capsules is a dietary supplement by Higher Nature Aeterna Gold with 1 active ingredient. Its ingredients are commonly taken for antioxidant support, skin health and aging, eye health.Based on those ingredients, 671 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are AstaPure Pure Astaxanthin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Astaxanthin Capsules by Higher Nature Aeterna Gold

Ask about any prescription or over-the-counter medication and we check it for interactions with Astaxanthin Capsules by Higher Nature Aeterna Gold — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Astaxanthin Capsules by Higher Nature Aeterna Gold

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: AstaPure Pure Astaxanthin, a carotenoid (a type of plant pigment with antioxidant properties). The inactive ingredients are extra virgin olive oil, glycerol, carrageenan, sodium carbonate, D-alpha-tocopherol, and a capsule shell.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Astaxanthin's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Targets visible signs of aging; protects skin.
  • We looked for evidence on: Aging skin, Sunburn, Skin elasticity, Skin hydration, Photoaging.
  • The closest evidence on file: Astaxanthin is rated "Insufficient Reliable Evidence To Rate" for Aging skin (Natural Medicines).
  • Also on file: Astaxanthin is rated "Insufficient Reliable Evidence To Rate" for Sunburn.

The evidence for astaxanthin isn't established in our data for the uses listed — age-related cognitive decline, macular degeneration, aging skin, Alzheimer disease, athletic performance, and carpal tunnel syndrome all show insufficient reliable evidence to rate. That doesn't mean it doesn't work; it means the research so far isn't solid enough to make a claim.

If you're considering it for one of these reasons, talk with your doctor about what the current science actually supports.

The evidence, ingredient by ingredient Astaxanthin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Astaxanthin is generally well tolerated in studies, though long-term safety data are limited. The most common side effects are abdominal pain, diarrhea, and red or reddish-colored stool — the color change is just the pigment and not harmful.

At the standard dose (around 6 mg daily), these are mild; at much higher doses (40 mg daily), some people have reported severe stomach pain. There isn't enough safety data to know whether astaxanthin is safe in pregnancy or while breastfeeding.

The data advises against it during both. If you're pregnant, breastfeeding, or planning to become pregnant, talk with your doctor or pharmacist about whether this is right for you.

Side effects, ingredient by ingredient Astaxanthin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Astaxanthin.
  • The most serious interaction on file is rated Moderate.
  • For scale: 672 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your pharmacist before taking this if you use any drugs metabolized by the CYP3A4 or CYP2B6 enzymes in your liver — that's a broad list that includes common medications. This effect hasn't been proven in humans yet, only in lab studies, but it's worth confirming your specific prescriptions won't be affected.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Astaxanthin is one to check before you start if you take any regular medications, especially those your body clears through the liver. It's generally well tolerated at standard doses, but long-term safety data are sparse, and pregnancy and breastfeeding are not recommended based on current information.

Have a conversation with your own pharmacist or doctor about your medications and situation before adding it.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 24, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Astaxanthin Capsules, straight from the product label.

Brand Higher Nature Aeterna Gold
Barcode (UPC) 5031013106477
Net contents 30 Capsule(s)
Market status On market
Date entered into DSLD Jun 24, 2020
DSLD ID 223308
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Astaxanthin Capsules by Higher Nature Aeterna Gold, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
UPC/BARCODE
5031013106477
IngredientAmount% DV
AstaPure Pure Astaxanthin4 mg--

Other ingredients: extra virgin Olive Oil, Capsule, Glycerol, Carrageenan, Sodium Carbonate, Astaxanthin, D-Alpha-Tocopherol

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Free From: Artificial colours, flavourings or preservatives, dairy products, gluten, lactose, sugar, wheat, yeast.

Suitable for vegetarians and vegans.

Targets the visible signs of ageing Protects your skin from within Perfect partner to collagen For supple, hydrated skin

General Statements

This product is not tested on animals.

Beauty from within Nature's beauty secret One month's supply

Brand IP Statement(s)

AstaPure is a registered trademark.

FDA Statement of Identity

Food Supplement

Suggested/Recommended/Usage/Directions

Directions: Adults, take 1 capsule a day, with a meal. Do not exceed recommended daily intake.

Precautions

Food supplements should not be used as a substitute for a varied and balanced diet and healthy lifestyle.

Store in a cool, dry place out of reach of children.

Storage

Store in a cool, dry place out of reach of children.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Astaxanthin Capsules by Higher Nature Aeterna Gold label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Astaxanthin Capsules label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Astaxanthin Capsules by Higher Nature Aeterna Gold

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

AstaPure Pure Astaxanthin

Interacts with
671 drugs
4 mg per serving Form: Haematococcus pluvialis

Astaxanthin is a reddish carotenoid pigment with strong antioxidant activity in the lab, and it is widely promoted for skin, eye, heart, and exercise...

AstaPure Pure Astaxanthin monograph & interactions

Other (inactive) ingredients: Extra virgin Olive Oil, Capsule, Glycerol, Carrageenan, Sodium Carbonate, Astaxanthin, D-Alpha-Tocopherol. These complete the product’s ingredient list but are not active constituents.

Interaction report

Astaxanthin Capsules by Higher Nature Aeterna Gold Drug Interactions

Want to check YOUR meds against Astaxanthin Capsules?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
671Drugs
671 Moderate

Ingredients driving the most interactions

AstaPure Pure Astaxanthin 671

Individual Drug Interactions

The ingredients in Astaxanthin Capsules interact with 671 drugs. Click any drug to see the details.

1 of the 1 ingredient in Astaxanthin Capsules interact with drugs. Each result below shows which ingredient is responsible. AstaPure Pure Astaxanthin

Each ingredient & the kinds of drugs it affects

For each ingredient in Astaxanthin Capsules with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

AstaPure Pure Astaxanthin2 drug types · 671 drugs

Cytochrome P450 2B6 (Cyp2B6) Substrates

Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP2B6.
In vitro research shows that astaxanthin induces cytochrome CYP2B6 enzyme activity in human hepatocytes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP3A4.
In vitro research shows that astaxanthin induces CYP3A4 enzyme activity in human hepatocytes. This effect has not been reported in humans.

Likelihood Possible Evidence D
AstaPure Pure Astaxanthin full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Astaxanthin Capsules, from the product label.

Higher Nature Aeterna Gold

See all Higher Nature Aeterna Gold products
Name
Higher Nature Ltd
City
Burwash Common TN19 7LX
State
East Sussex
Web Address
highernature.com
Pharmacist Counseling Corner

Astaxanthin Capsules by Higher Nature Aeterna Gold: Common Questions

Does Astaxanthin Capsules by Higher Nature Aeterna Gold interact with any medications?
Yes. Based on its ingredients, Astaxanthin Capsules has a known interaction with 671 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Astaxanthin Capsules contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is astaxanthin and where does it come from?
Astaxanthin is a reddish pigment from plants called a carotenoid. It has antioxidant properties — meaning it may help protect cells from damage — but the research into what it actually does for human health is still developing.
Will this cause red-colored stool?
Yes, it can. Red or reddish stool is one of the most common side effects and is just the astaxanthin pigment passing through your digestive system. It's not dangerous, just a cosmetic change you might notice.
Is astaxanthin safe to take while I'm pregnant or breastfeeding?
The safety data aren't there to say it's okay, so it's best to avoid it during pregnancy and while breastfeeding. If you're in either situation, talk with your doctor or pharmacist about whether it's right for you.
What conditions does astaxanthin actually help with?
We don't have solid evidence in our data for any of the uses listed — including cognitive decline, macular degeneration, or aging skin. That's not a yes or no; it just means the research isn't strong enough to make a claim yet.
What are the side effects I should expect?
Most people tolerate it well. The most common side effects are abdominal discomfort, diarrhea, and red stool. At standard doses these are usually mild, though some people on much higher doses have reported severe stomach pain.
How many active ingredients are in this capsule?
Just one: astaxanthin. The rest are inactive ingredients like olive oil, glycerol, and the capsule shell itself.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Astaxanthin Capsules is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Astaxanthin Capsules label
Go deeper

The Full Monographs Behind Astaxanthin Capsules’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Astaxanthin

Interacts with 671 drugs

Astaxanthin is a reddish carotenoid pigment with strong antioxidant activity in the lab, and it is widely promoted for skin, eye, heart, and exercise benefits. Early human studies are promis...

Read the full Astaxanthin monograph →
Sources

Sources & How We Checked

Astaxanthin Capsules's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Astaxanthin 3 references
  1. Kupcinskas L, Lafolie P, Lignell A, et al. Efficacy of the natural antioxidant astaxanthin in the treatment of functional dyspepsia in patients with or without Helicobacter pylori infection: A prospective, randomized, double blind, and placebo-controlled
  2. Kistler, A., Liechti, H., Pichard, L., Wolz, E., Oesterhelt, G., Hayes, A., and Maurel, P. Metabolism and CYP-inducer properties of astaxanthin in man and primary human hepatocytes. Arch.Toxicol. 2002;75(11-12):665-675. PubMed
  3. Choi HD, Youn YK, Shin WG. Positive effects of astaxanthin on lipid profiles and oxidative stress in overweight subjects. Plant Foods Hum Nutr. 2011;66:363-369. PubMed

See these in context on the Astaxanthin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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