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Dietary supplement

Ayur-Sida Cordifolia Ingredients & Drug Interactions

by Douglas Laboratories

Ayur-Sida Cordifolia label
See full label image
Capsule Category: Botanical
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Ayur-Sida Cordifolia against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Ayur-Sida Cordifolia is a dietary supplement by Douglas Laboratories with 1 active ingredient. Its ingredients are commonly taken for weight loss and energy, asthma and breathing problems, joint and muscle pain.Based on those ingredients, 445 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Sida cordifolia Linn. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Ayur-Sida Cordifolia by Douglas Laboratories

Ask about any prescription or over-the-counter medication and we check it for interactions with Ayur-Sida Cordifolia by Douglas Laboratories — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Ayur-Sida Cordifolia by Douglas Laboratories

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Ayur-Sida Cordifolia contains one active ingredient: sida cordifolia Linn, an herb that provides ephedrine, a stimulant compound. The product also contains inactive ingredients — gelatin, cellulose, and vegetable stearate — which serve as capsule material and fillers.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Sida Cordifolia product and its label doesn't state a use — see Sida Cordifolia's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The product facts we hold do not include any effectiveness ratings for sida cordifolia. We cannot tell you from our data whether this supplement is effective for any condition.

The evidence, ingredient by ingredient Sida Cordifolia

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

This is important: sida cordifolia contains ephedrine, a stimulant linked to serious heart and blood pressure risks, and it's banned in many products for that reason. The herb has been associated with a wide range of adverse effects — from dizziness, restlessness, insomnia, and headache to severe cardiovascular problems like heart palpitations, irregular heartbeats, heart attack, stroke, and sudden cardiac death.

Long-term or high-dose use may also lead to dependence and tolerance. The safety data advises against use during pregnancy and while breastfeeding.

Ephedrine can pass into breast milk and harm a nursing baby, and stimulant exposure in pregnancy carries documented risks.

Side effects, ingredient by ingredient Sida Cordifolia

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Sida Cordifolia.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: diabetes medications; heart-rhythm medications.
  • For scale: 445 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, check with your doctor or pharmacist if you take any QT interval-prolonging drugs (heart rhythm medications), stimulants, caffeine or theophylline, diabetes medications, dexamethasone, MAOIs (a type of antidepressant), or ergot derivatives (migraine treatments). The first three categories carry Major-severity risks and require particular caution.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Major medication interactions have been identified, and safety information is well characterized.

This product is not for most people — ephedrine's cardiovascular risks are well-established and serious. If you have any heart condition, high blood pressure, diabetes, or take any medications, especially stimulants, heart rhythm drugs, or antidepressants, do not use this without talking to your doctor or pharmacist first.

Anyone who is pregnant or breastfeeding should avoid it entirely. Talk with your own healthcare provider before considering this supplement.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 1, 2012.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Ayur-Sida Cordifolia, straight from the product label.

Brand Douglas Laboratories
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD Jun 1, 2012
DSLD ID 9025
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Ayur-Sida Cordifolia by Douglas Laboratories, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
IngredientAmount% DV
Sida cordifolia Linn100 mg--

Other ingredients: Gelatin, Cellulose, Vegetable Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Tamper resistant package, do not use if outer seal is missing.

KEEP OUT OF REACH OF CHILDREN.

General

Formula #7680

FDA Statement of Identity

A Dietary Supplement

Formulation

This product contains NO yeast, wheat gluten, soy protein, milk/dairy, corn, sodium, sugar, starch, artificial coloring, preservatives or flavoring.

Suggested/Recommended/Usage/Directions

Suggested Usage: As a dietary supplement, adults take 1 capsule daily or as directed by your healthcare professional.

Storage

For optimal storage conditions, store in a cool, dry place. (59(0)-77(0)F/15(0)-25(0)C) (35-65% relative humidity)

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Ayur-Sida Cordifolia by Douglas Laboratories label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Ayur-Sida Cordifolia label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Ayur-Sida Cordifolia by Douglas Laboratories

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Sida cordifolia Linn

Interacts with
445 drugs
100 mg per serving Form: Alkaloids

Sida cordifolia (bala or country mallow) is a traditional Ayurvedic plant that naturally contains ephedrine, a powerful stimulant. Because of this, ma...

Sida cordifolia Linn monograph & interactions

Other (inactive) ingredients: Gelatin, Cellulose, Vegetable Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Ayur-Sida Cordifolia by Douglas Laboratories Drug Interactions

Want to check YOUR meds against Ayur-Sida Cordifolia?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
445Drugs
337 Major 108 Moderate

Ingredients driving the most interactions

Sida cordifolia Linn 445

Individual Drug Interactions

The ingredients in Ayur-Sida Cordifolia interact with 445 drugs. Click any drug to see the details.

1 of the 1 ingredient in Ayur-Sida Cordifolia interact with drugs. Each result below shows which ingredient is responsible. Sida cordifolia Linn

Each ingredient & the kinds of drugs it affects

For each ingredient in Ayur-Sida Cordifolia with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Sida cordifolia Linn7 drug types · 445 drugs

Methylxanthines

Theoretically, Sida cordifolia might increase the risk of serious adverse effects when taken with methylxanthines.
Sida cordifolia contains ephedrine. Use of ephedrine-containing herbs with caffeine or other methylxanthines such as theophylline might increase the risk of stimulatory adverse effects. Some clinical research and case reports suggest that using ephedrine with caffeine might increase the risk of serious life-threatening or debilitating adverse effects such as hypertension, myocardial infarction (MI), stroke, seizures, and death.

Likelihood Probable Evidence D
Qt Interval-Prolonging Drugs

Theoretically, Sida cordifolia might increase the risk of additive QT interval prolongation when taken with QT interval-prolonging drugs.
Sida cordifolia contains ephedrine. Clinical research shows that ephedrine from another herb, ephedra, can prolong the QT interval.

Likelihood Probable Evidence B
Stimulant Drugs

Theoretically, Sida cordifolia might increase the risk of adverse cardiovascular effects when taken with stimulant drugs.
Sida cordifolia contains ephedrine. Drugs with CNS stimulant properties, such as phenylpropanolamine, pseudoephedrine, and diethylpropion, and many others can increase the risk of hypertension and adverse cardiovascular effects when taken with ephedrine.

Likelihood Probable Evidence D
Antidiabetes Drugs

Theoretically, Sida cordifolia might reduce the effectiveness of antidiabetes drugs.
Sida cordifolia contains ephedrine. Clinical research shows that ephedrine can increase blood glucose levels.

Likelihood Probable Evidence B
Dexamethasone (Decadron)

Theoretically, Sida cordifolia might reduce the effectiveness of dexamethasone.
Sida cordifolia contains ephedrine. Clinical research shows that ephedrine can increase the clearance rate of dexamethasone.

Likelihood Possible Evidence B
Ergot Derivatives

Theoretically, Sida cordifolia might increase the risk of additive hypertension when taken with ergot derivatives.
Sida cordifolia contains ephedrine, which can cause vasoconstriction. This can lead to significant elevations in blood pressure when taken with ergot derivatives.

Likelihood Probable Evidence B
Monoamine Oxidase Inhibitors (Maois)

Theoretically, Sida cordifolia might increase the risk of hypertension when taken with MAOIs.
Sida cordifolia contains ephedrine. Clinical research shows that ephedrine can increase blood pressure.

Likelihood Probable Evidence B
Sida cordifolia Linn full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Ayur-Sida Cordifolia, from the product label.

Douglas Laboratories

See all Douglas Laboratories products
Name
Douglas Laboratories
Street Address
600 Boyce Road
City
Pittsburgh
State
PA
ZipCode
15205
Web Address
www.douglaslabs.com
Pharmacist Counseling Corner

Ayur-Sida Cordifolia by Douglas Laboratories: Common Questions

Does Ayur-Sida Cordifolia by Douglas Laboratories interact with any medications?
Yes. Based on its ingredients, Ayur-Sida Cordifolia has a known interaction with 445 medications, including 337 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Ayur-Sida Cordifolia contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is sida cordifolia, and what is it supposed to do?
Sida cordifolia is a plant that contains ephedrine, a stimulant compound. We don't have effectiveness data in our files for what this supplement is claimed to do, so I can't tell you whether it works for its intended purpose.
What side effects could I get from taking this?
Ephedrine-containing products have been linked to dizziness, restlessness, irritability, insomnia, headache, anxiety, and personality changes. More seriously, they can cause heart palpitations, irregular heartbeats, high blood pressure, heart attack, stroke, and even sudden cardiac death. Long-term use may also lead to dependence.
Can I take this while pregnant or breastfeeding?
No — the safety data advises against it during both pregnancy and breastfeeding. Ephedrine can harm a developing baby and passes into breast milk where it can harm a nursing infant.
Why is this product considered risky?
Sida cordifolia contains ephedrine, a stimulant that's been linked to serious cardiovascular problems — heart attacks, strokes, and sudden cardiac death — and it's been banned in many products because of these risks. It also interacts with a very large number of medications.
What inactive ingredients are in this?
The capsule contains gelatin, cellulose, and vegetable stearate. These are fillers and capsule materials, not active ingredients.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Ayur-Sida Cordifolia label
Go deeper

The Full Monographs Behind Ayur-Sida Cordifolia’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Sida Cordifolia

Interacts with 445 drugs

Sida cordifolia (bala or country mallow) is a traditional Ayurvedic plant that naturally contains ephedrine, a powerful stimulant. Because of this, many supplements containing it have been b...

Read the full Sida Cordifolia monograph →
Sources

Sources & How We Checked

Ayur-Sida Cordifolia's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 29 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Sida Cordifolia 29 references
  1. Okada S, Rohan PJ, Miller FW, et al. Myopathies following ingestion of special nutritional products. Arthritis Rheum 1996;39:349.
  2. Zaacks SM, Klein L, Tan CD, et al. Hypersensitivity myocarditis associated with ephedra use. J Toxicol Clin Toxicol 1999;37:485-9. PubMed
  3. Powell T, Hsu FF, Turk J, Hruska K. Ma-huang strikes again: ephedrine nephrolithiasis. Am J Kidney Dis 1998;32:153-9. PubMed
  4. Theoharides TC. Sudden death of a healthy college student related to ephedrine toxicity from a ma-huang containing drink. J Clin Psychopharmacol 1997;17:437-9. PubMed
  5. Vahedi K, Domingo V, Amarenco P, Bousser MG. Ischemic stroke in a sportsman who consumed MaHuang extract and creatine monohydrate for bodybuilding. J Neurol Neurosurg Psychiatr 2000;68:112-3.
  6. Doyle H, Kargin M. Herbal stimulant containing ephedrine has also caused psychosis. BMJ 1996;313:756. PubMed
  7. For Dieter, Nearly the Ultimate Loss. The Washington Post. Available at: http://www.washingtonpost.com/archive/politics/2000/03/19/for-dieter-nearly-the-ultimate-loss/c0f07474-489d-4f44-bc17-1f1367c956ae/ (Accessed 19 March 2000).
  8. FDA Takes Aim at Ephedra. The Washington Post. Available at: http://www.washingtonpost.com/archive/politics/2000/03/19/fda-takes-aim-at-ephedra/4ce534a7-d291-44ec-88a8-38e97ff27e3b/ (Accessed 19 March 2000).
  9. FDA. Proposed rule: dietary supplements containing ephedrine alkaloids. Available at: www.verity.fda.gov (Accessed 25 January 2000).
  10. Boozer CN, Nasser JA, Heymsfield SB, et al. An herbal supplement containing Ma Huang-Guarana for weight loss: a randomized, double-blind trial. Int J Obes Relat Metab Disord 2001;25:316-24. PubMed
  11. Anon. Sida Cordifolia. Metro Marketing, Inc. Available at: http://metromkt.net/viable/1sidacor.shtml (Accessed 9 March 2000).
  12. Gurley BJ, Gardner SF, Hubbard MA. Content versus label claims in ephedra-containing dietary supplements. Am J Health Syst Pharm 2000;57:963-9. PubMed
  13. White LM, Gardner SF, Gurley BJ, et al. Pharmacokinetics and Cardiovascular Effects of Ma-Huang (Ephedra sinica) in Normotensive Adults. J Clin Pharmacol 1997;37:116-22.
  14. Haller CA, Benowitz NL. Adverse cardiovascular and central nervous system events associated with dietary supplements containing ephedra alkaloids. N Engl J Med 2000;343:1833-8. PubMed
  15. Leikin JB, Klein L. Ephedra causes myocarditis. Clin Toxicol 2000;38:353-4.
  16. Jacobs KM, Hirsch KA. Psychiatric complications of Ma-huang. Psychosomatics 2000;41:58-62. PubMed
  17. Dulloo AG. Herbal simulation of ephedrine and caffeine in treatment of obesity. Int J Obes Relat Metab Disord 2002;26:590-2. PubMed
  18. Samenuk D, Link MS, Homoud MK, et al. Adverse cardiovascular events temporally associated with ma huang, an herbal source of ephedrine. Mayo Clin Proc 2002;77:12-6. PubMed
  19. Boozer CN, Daly PA, Homel P, et al. Herbal ephedra/caffeine for weight loss: a 6-month randomized safety and efficacy trial. Int J Obes Relat Metab Disord 2002;26:593-604. PubMed
  20. Morgenstern LB, Viscoli CM, Kernan WN, et al. Use of Ephedra-containing products and risk for hemorrhagic stroke. Neurology 2003;60:132-5. .
  21. Kalman D, Incledon T, Gaunaurd I, et al. An acute clinical trial evaluating the cardiovascular effects of an herbal ephedra-caffeine weight loss product in healthy overweight adults. Int J Obes 2002;26:1363-66.. PubMed
  22. Kockler DR, McCarthy MW, Lawson CL. Seizure activity and unresponsiveness after hydroxycut ingestion. Pharmacotherapy 2001;21:647-51.. PubMed
  23. Yates KM, O'Connor A, Horsley CA. "Herbal Ecstasy": a case series of adverse reactions. N Z Med J 2000;113:315-7..
  24. Walton R, Manos GH. Psychosis related to ephedra-containing herbal supplement use. South Med J 2003;96:718-20.. PubMed
  25. Jenkins DJ, Wesson V, Wolever TM, et al. Wholemeal versus wholegrain breads: proportion of whole or cracked grain and the glycaemic response. BMJ 1988;297:958-60. PubMed
  26. McBride BF, Karapanos AK, Krudysz A, et al. Electrocardiographic and hemodynamic effects of a multicomponent dietary supplement containing ephedra and caffeine: a randomized controlled trial. JAMA 2004;291:216-21. PubMed
  27. Brooks SM, Sholiton LJ, Werk EE Jr, Altenau P. The effects of ephedrine and theophylline on dexamethasone metabolism in bronchial asthma. J Clin Pharmacol 1977;17:308-18. PubMed
  28. Gardner SF, Franks AM, Gurley BJ, et al. Effect of a multicomponent, ephedra-containing dietary supplement (Metabolife 356) on Holter monitoring and hemostatic parameters in healthy volunteers. Am J Cardiol 2003;91:1510-3, A9. PubMed
  29. Haller CA, Jacob P 3rd, Benowitz NL. Enhanced stimulant and metabolic effects of combined ephedrine and caffeine. Clin Pharmacol Ther 2004;75:259-73.

See these in context on the Sida Cordifolia monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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