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Dietary supplement

Beef Liver Ingredients & Drug Interactions

by Smidge

Beef Liver label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Minor
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Beef Liver against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Minor

Beef Liver is a dietary supplement by Smidge with 1 active ingredient. Its ingredients are commonly taken for anemia and low iron, vitamin b12 support, general energy and fatigue.Based on those ingredients, 3 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Beef Liver, Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Beef Liver by Smidge

Ask about any prescription or over-the-counter medication and we check it for interactions with Beef Liver by Smidge — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Beef Liver by Smidge

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Smidge Beef Liver contains one active ingredient: beef liver powder. It's a whole-food concentrate — essentially dehydrated liver from cattle — packaged in a gelatin capsule.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Liver Extract product and its label doesn't state a use — see Liver Extract's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence we hold rates this product possibly ineffective for chronic fatigue syndrome. For hepatitis C, there isn't enough reliable evidence to say whether it works or not.

If you're considering it for either of those conditions, talk with your doctor about whether it makes sense for you.

The evidence, ingredient by ingredient Liver Extract

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

No adverse reactions have been reported in the data we hold, but a thorough safety evaluation hasn't been done. The bigger concern is that liver extract delivers very high levels of vitamin A and iron, which can be problematic in large or long-term doses.

There's also a theoretical risk of contamination — liver comes from slaughterhouses and may come from sick animals, and in countries where BSE (bovine spongiform encephalopathy, or mad cow disease) has been documented, there's a small theoretical risk of contaminated tissue. No cases of BSE transfer to humans from liver extract have been reported, but the risk isn't zero.

During pregnancy, liver products carry a caution because of their very high vitamin A content, which may harm a developing baby — avoid unless your doctor specifically advises otherwise. Safety during breastfeeding hasn't been well studied, so check with your doctor before using.

Side effects, ingredient by ingredient Liver Extract

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Liver Extract.
  • The most serious interaction on file is rated Minor.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 3 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Double-check this product if you take warfarin (Coumadin) — the vitamin K in beef liver could theoretically reduce how well it works — or if you're on iron supplements or iron-containing medications, which could boost your total iron intake. Both interactions are rated Minor, but they haven't been fully studied in people.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Only minor medication interactions are documented, and safety information is well characterized.

Beef liver is generally well tolerated in food amounts for healthy adults, but this supplement delivers concentrated levels of vitamin A and iron. If you take warfarin or iron supplements, you'll want to check those interactions first.

Pregnant people should avoid it unless their doctor says otherwise. Talk to your pharmacist before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Beef Liver, straight from the product label.

Brand Smidge
Barcode (UPC) 850019902099
Net contents 120 Capsule(s)
Market status On market
Date entered into DSLD Sep 25, 2025
DSLD ID 337905
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), No Allergies, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Beef Liver by Smidge, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
4 Capsule(s)
Maximum serving Sizes:
4 Capsule(s)
Servings per container
30
UPC/BARCODE
850019902099
IngredientAmount% DV
Beef Liver, Powder2400 mg--

Other ingredients: Gelatin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Smidge Always start with a Smidge.

Suggested/Recommended/Usage/Directions

Suggested use: Take 4 capsules at once, per day, or as directed by a practitioner.

Formula

Smidge Beef Liver capsules deliver all the nutrients of fresh-cooked liver, without the unpleasant taste. Our full-fat beef liver comes from grass-fed cattle of New Zealand and contains no additives or fillers.

Formulation

Our full-fat beef liver comes from grass-fed cattle of New Zealand and contains no additives or fillers. Excluding capsule ingredients. Free of the following common allergens: milk/casein, eggs, fish, shellfish, tree nuts, peanuts, wheat, gluten, sesame, and soybeans. No artificial colors, flavors, or preservatives.

Grass Fed, Pasture Raised Freeze Dried, Never Heated

No Fillers

Product of New Zealand.

Smidge supplements are guaranteed clean and potent.

Storage

Storage: Store in a cool, dry place.

Precautions

Do not use if the safety seal is broken or missing.

Keep out of reach of children.

FDA Disclaimer Statement

This product is not intended to diagnose, treat, cure or prevent disease.

General Statements

Small Batch Supplements

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Beef Liver by Smidge label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Beef Liver label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Beef Liver by Smidge

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size4 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Beef Liver, Powder

Interacts with
3 drugs
2400 mg per serving

Liver extract is a dried or concentrated form of animal liver that is naturally rich in iron, vitamin B12, vitamin A, and other nutrients. It was once...

Beef Liver, Powder monograph & interactions

Other (inactive) ingredients: Gelatin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Beef Liver by Smidge Drug Interactions

Want to check YOUR meds against Beef Liver?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
3Drugs
3 Minor

Ingredients driving the most interactions

Beef Liver, Powder 3

Individual Drug Interactions

The ingredients in Beef Liver interact with 3 drugs. Click any drug to see the details.

1 of the 1 ingredient in Beef Liver interact with drugs. Each result below shows which ingredient is responsible. Beef Liver, Powder

Each ingredient & the kinds of drugs it affects

For each ingredient in Beef Liver with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Beef Liver, Powder2 drug types · 3 drugs

Iron

Liver extract can contain heme iron. Taking liver extract with iron-containing medications or supplements may increase total iron intake and could increase the risk of gastrointestinal adverse effects or excessive iron accumulation. The risk is greater with high doses, prolonged use, or in individuals with hemochromatosis or another iron-overload disorder. Review the iron content of the liver extract and the total elemental iron dose. Avoid unnecessary duplicate iron supplementation and consider monitoring ferritin and transferrin saturation when clinically appropriate.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Liver extract products may contain small and variable amounts of vitamin K. Theoretically, starting, stopping, or substantially changing the amount of liver extract used could reduce the anticoagulant effect of warfarin and lower the INR. However, this interaction has not been directly studied or reported in humans, and the vitamin K content of liver extract products is generally not standardized. Consider monitoring the INR after a meaningful change in liver extract use.

Likelihood Possible Evidence C
Beef Liver, Powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Beef Liver, from the product label.

Smidge

See all Smidge products
Name
Organic 3, Inc.
Street Address
26677 W. 12 Mile Rd.
City
Southfield
State
MI
ZipCode
48034
Phone Number
888-524-6585
Web Address
www.GetSmidge.com
Pharmacist Counseling Corner

Beef Liver by Smidge: Common Questions

Does Beef Liver by Smidge interact with any medications?
Yes. Based on its ingredients, Beef Liver has a known interaction with 3 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Beef Liver contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant?
Liver products contain very high levels of vitamin A, which can harm a developing baby. The data advises against use during pregnancy unless your doctor tells you otherwise. Talk with your doctor or pharmacist about what's right for you.
What is beef liver powder and why would I take it?
It's dehydrated, powdered liver from cattle — a whole-food concentrate. People use it for various reasons, though the evidence we hold rates it possibly ineffective for chronic fatigue syndrome and shows insufficient evidence for hepatitis C.
Are there any reported side effects?
No adverse reactions have been reported in our data. However, a complete safety evaluation hasn't been done, and the product does deliver high amounts of vitamin A and iron, which can cause problems at high or prolonged doses.
Does this contain any other ingredients besides beef liver?
The capsule itself is made of gelatin, but that's an inactive ingredient. The only active ingredient is beef liver powder.
Should I worry about BSE (mad cow disease) from this product?
Liver extract comes from cattle and there's a theoretical risk in countries where BSE has been reported. However, no cases of BSE transfer to humans from liver extract products have ever been documented. Still, if you want to be cautious, you can look for products sourced from countries without BSE.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Beef Liver is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Beef Liver label
Go deeper

The Full Monographs Behind Beef Liver’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Liver Extract

Interacts with 3 drugs

Liver extract is a dried or concentrated form of animal liver that is naturally rich in iron, vitamin B12, vitamin A, and other nutrients. It was once used to treat certain anemias before pu...

Read the full Liver Extract monograph →
Sources

Sources & How We Checked

Beef Liver's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Liver Extract 4 references
  1. Lewis CJ. Letter to reiterate certain public health and safety concerns to firms manufacturing or importing dietary supplements that contain specific bovine tissues. FDA. Available at: www.cfsan.fda.gov/~dms/dspltr05.html.
  2. Kaslow JE, Rucker L, Onishi R. Liver extract-folic acid-cyanocobalamin vs placebo for chronic fatigue syndrome. Arch Intern Med 1989;149:2501-3. DOI
  3. Ebinuma, H., Saito, H., Tada, S., Masuda, T., Kamiya, T., Nishida, J., Yoshioka, M., and Ishii, H. Additive therapeutic effects of the liver extract preparation mixture adelavin-9 on interferon-beta treatment for chronic hepatitis C. Hepatogastroenterolog
  4. Saito, H., Ebinuma, H., Tada, S., Tsunematsu, S., Atsukawa, K., Masuda, T., Tsuchiya, M., and Ishii, H. Enhancing effect of the liver extract and flavin adenin dinucleotide mixture on anti-viral efficacy of interferon in patients with chronic hepatitis C. PubMed

See these in context on the Liver Extract monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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