No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Benfotiamine Ingredients & Drug Interactions

by Seeking Health

Capsule Category: Vitamin
No known interaction
The interaction bottom line No known interaction

Benfotiamine is a dietary supplement by Seeking Health with 1 active ingredient. Its ingredients are commonly taken for diabetic nerve pain (neuropathy), supporting healthy nerve function, thiamine deficiency.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Benfotiamine by Seeking Health

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: benfotiamine, a fat-soluble form of thiamine (vitamin B1). The capsule shell and the fillers inside — cellulose, L-leucine, and silicon dioxide — are inactive ingredients that help deliver the benfotiamine.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: vitamin B1 supplement with high bioavailability.
  • We looked for evidence on: Diabetic neuropathy, Peripheral neuropathy, thiamine deficiency, nerve damage.
  • The strongest evidence on file: Benfotiamine is rated "Possibly Effective" for Diabetic neuropathy (Natural Medicines).
  • Also on file: Benfotiamine is rated "Insufficient Reliable Evidence To Rate" for Peripheral neuropathy.

Benfotiamine has possibly effective evidence for diabetic neuropathy (nerve damage from high blood sugar). For diabetic kidney disease (nephropathy), the evidence suggests it's possibly ineffective.

For alcohol use disorder, Alzheimer disease, and peripheral neuropathy, we don't have enough reliable evidence yet to say whether it works or doesn't. If you're considering it for diabetic nerve pain, talk with your doctor about whether the evidence fits your situation.

The evidence, ingredient by ingredient Benfotiamine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Benfotiamine is generally well tolerated in short-term studies, but long-term safety hasn't been fully established. The most common reported side effects in trials were mild — a small number of participants reported allergic skin reactions or slight stomach discomfort, and these occurred at rates no different from placebo.

There isn't enough safety information during pregnancy, so avoid it unless your doctor advises otherwise. Safety while breastfeeding has not been well studied, so caution is advised if you're nursing — talk with your doctor or pharmacist before taking it.

Side effects, ingredient by ingredient Benfotiamine

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we checked. Before starting, use the medication search tool on this page to confirm your own prescriptions, and ask your doctor or pharmacist if you have any questions.

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Benfotiamine may be worth considering if you have diabetic nerve pain and want to explore a possibly effective option alongside your doctor's care plan. If you're pregnant, planning to become pregnant, or breastfeeding, check with your doctor first — the safety data isn't solid enough to say it's okay on your own.

No medication interactions are documented for this ingredient, but run your specific drugs through the tool below and confirm with your pharmacist before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 23, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Benfotiamine, straight from the product label.

Brand Seeking Health
Barcode (UPC) 828054149861
Net contents 60 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Mar 23, 2018
DSLD ID 174370
Product type Vitamin
Supplement form Capsule
Dietary claims / uses Nutrient, All Other
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Benfotiamine by Seeking Health, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
828054149861
IngredientAmount% DV
Benfotiamine150 mg10000%

Other ingredients: Vegetarian Capsule, Cellulose, L-Leucine, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Benfotiamine is a lipid-soluble derivative of vitamin B1 (thiamine) with high bioavailability. It is better absorbed than water-soluble forms of thiamine and has an estimated bioavailability of up to 3.6 times as high as compared to thiamine hydrochloride, making benfotiamine especially useful for people with absorption difficulties.

This product was made in a GMP and ISO 9001:2008 registered facility.

Physician formulated

Precautions

Do not use if shrinkwrap is broken or missing.

Keep out of reach of children.

Storage

Store in a cool, dry place (59(0)F-85(0)F) away from direct light.

FDA Statement of Identity

Vitamin B1 Supplement

Formula

Vitamin B1 Supplement

Formulation

Does Not Contain: Milk/casien, eggs, fish, shellfish, tree nuts, peanuts, wheat/gluten, yeast, and soybeans. Contains no artificial colors, flavors, or preservatives.

Suggested/Recommended/Usage/Directions

Suggested Use: 1 capsule daily with food or as directed by your health care professional.

See for yourself

Benfotiamine by Seeking Health label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Benfotiamine by Seeking Health

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Benfotiamine

No known
interactions
150 mg per serving

Benfotiamine is a man-made, fat-soluble form of vitamin B1 (thiamine) that the body may absorb more easily than regular thiamine. It is mostly studied...

Benfotiamine monograph & interactions

Other (inactive) ingredients: Vegetarian Capsule, Cellulose, L-Leucine, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Benfotiamine by Seeking Health Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Benfotiamine. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Benfotiamine, from the product label.

Seeking Health

See all Seeking Health products
Name
Seeking Health
Street Address
3140 Mercer Ave
City
Bellingham
State
WA
ZipCode
98225
Phone Number
(800) 547-9812
Web Address
www.seekinghealth.com
Pharmacist Counseling Corner

Benfotiamine by Seeking Health: Common Questions

Does Benfotiamine by Seeking Health interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Benfotiamine. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Benfotiamine contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is benfotiamine, and how is it different from regular B1?
Benfotiamine is a fat-soluble form of thiamine (vitamin B1), which means your body may absorb it more easily than standard B1 supplements. It's designed to help with nerve-related issues, particularly in people with diabetes.
Will this help my diabetic nerve pain?
Benfotiamine has possibly effective evidence for diabetic neuropathy (nerve damage from high blood sugar). That means some evidence supports it, but it's not definitive — talk with your doctor about whether it's a good fit for your specific situation.
What side effects might I experience?
In clinical trials, a small number of people reported mild allergic skin reactions or slight stomach discomfort. Overall, side effects occurred at rates no different from placebo, so it's generally well tolerated in the short term.
Is it safe to take while I'm pregnant or breastfeeding?
There isn't enough safety information during pregnancy, so avoid it unless your doctor advises otherwise. Safety while breastfeeding also hasn't been well studied — talk with your doctor or pharmacist before taking it if you're nursing.
Does benfotiamine interact with any of my medications?
No interactions are documented in our data for benfotiamine. That said, use the medication checker on this page to confirm your specific drugs, and ask your pharmacist if you have any concerns.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Benfotiamine is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Benfotiamine label
Go deeper

The Full Monographs Behind Benfotiamine’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Benfotiamine's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 1 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Benfotiamine 1 reference
  1. Stracke H, Gaus W, Achenbach U, Federlin K, Bretzel RG. Benfotiamine in diabetic polyneuropathy (BENDIP): results of a randomised, double blind, placebo-controlled clinical study. Exp Clin Endocrinol Diabetes 2008;116(10):600-5. PubMed

See these in context on the Benfotiamine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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