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Dietary supplement

Benfotiamine-V 150 mg Ingredients & Drug Interactions

by Benfotiamine.Net, Inc.

Capsule Category: Vitamin
Most serious interaction: Minor
The interaction bottom line Most serious interaction: Minor

Benfotiamine-V 150 mg is a dietary supplement by Benfotiamine.Net, Inc. with 1 active ingredient. Its ingredients are commonly taken for preventing or treating thiamine deficiency, beriberi, wernicke-korsakoff syndrome (alcohol-related).Based on those ingredients, 3 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Thiamine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Benfotiamine-V 150 mg by Benfotiamine.Net, Inc.

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Partial disclosure
Ingredient Transparency · database check
Partial

Most active ingredients list an amount, but at least one is hidden in a blend or missing.

Why this rating?
  • The label discloses an exact amount for 1 of its 2 active ingredients.
  • “Thiamine” is listed as a grouped ingredient — the label gives one combined amount (103 mg) without saying how much of each component you get.

Benfotiamine-V contains 2 active ingredients: thiamine, benfotiamine, and S-benzoylithiamine-O-monophosphate — all forms of thiamine (vitamin B1) designed to support nerve health. The product also contains inactive ingredients (microcrystalline cellulose, stearic acid, and hydroxypropyl methylcellulose), which are fillers and binders that help form and stabilize the capsule.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Nerve function and oxidative stress support.
  • We looked for evidence on: Thiamine deficiency, Diabetic neuropathy, Peripheral neuropathy, Wernicke-Korsakoff syndrome (WKS), Alcohol use disorder, neuropathic pain — and 1 related terms.
  • The strongest evidence on file: Benfotiamine is rated "Possibly Effective" for Diabetic neuropathy (Natural Medicines).
  • Also on file: Benfotiamine is rated "Insufficient Reliable Evidence To Rate" for Alcohol use disorder, Peripheral neuropathy.

Benfotiamine is possibly effective for diabetic neuropathy (nerve damage from diabetes). It's rated possibly ineffective for diabetic nephropathy (kidney damage from diabetes).

For alcohol use disorder, Alzheimer disease, and peripheral neuropathy (nerve damage in the limbs), the evidence isn't established enough to rate it one way or the other. The data on S-benzoylithiamine-O-monophosphate shows the same effectiveness profile.

The evidence, ingredient by ingredient Thiamine Benfotiamine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Both benfotiamine and S-benzoylithiamine-O-monophosphate are generally well tolerated in studies, but long-term safety hasn't been fully studied. In a clinical trial of patients taking 300–600 mg daily for 6 weeks, a small number reported allergic skin reactions and slight stomach discomfort — rates no different from placebo.

There isn't enough safety information to use this product during pregnancy unless your doctor advises it. Safety while breastfeeding hasn't been well studied, so caution is advised; talk with your doctor or pharmacist.

Side effects, ingredient by ingredient Thiamine Benfotiamine

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. Still, talk with your doctor or pharmacist about your specific medications before you start.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glancePartially disclosed formula with some supporting evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Benfotiamine-V may be worth considering if you have diabetic nerve damage and want to try a possibly effective option. If you're pregnant, breastfeeding, or have long-term safety concerns, check with your doctor or pharmacist first.

No interactions are documented for the ingredients we could verify, but bring your full medication list to your pharmacist to be sure.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 21, 2012.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Benfotiamine-V 150 mg, straight from the product label.

Brand Benfotiamine.Net, Inc.
Barcode (UPC) 689076771528
Net contents 120 Vegetarian/Vegan Capsule(s)
Market status On market
Date entered into DSLD Nov 21, 2012
DSLD ID 15637
Product type Vitamin
Supplement form Capsule
Dietary claims / uses Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Benfotiamine-V 150 mg by Benfotiamine.Net, Inc., sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
4 Capsule(s)
Servings per container
120
UPC/BARCODE
689076771528
IngredientAmount% DV
Thiamine103 mg6875%
Benfotiamine150 mg--
S-benzoylithiamine-O-monophosphate0 NP--

Other ingredients: Microcrystalline Cellulose, Stearic Acid, Hydroxypropyl Methylcellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Benfotiamine, a lipid-soluble form of thiamine, dramatically boosts AGE-fighting thiamine pyrophosphate (TPP) and the cell-shielding activity of the enzyme transketolase in your body.

Benfotiamine

Encapsulated in an FDA-approved facility in the United States.

Toll Free: 1-888-493-8014 Online: http://www.benfotiamine.net

Suggested/Recommended/Usage/Directions

Recommended Use: Adults should take 1~4 servings per day or as directed by a medical practitioner.

Storage

Store in a cool dry place

Formula

S-benzoylthiamine-O-monophosphate*

FDA Statement of Identity

A Dietary Supplement

FDA Disclaimer Statement

*The FDA has not evaluated this compound. This compound is not intended to diagnose, treat, cure or prevent any disease.

See for yourself

Benfotiamine-V 150 mg by Benfotiamine.Net, Inc. label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Benfotiamine-V 150 mg by Benfotiamine.Net, Inc.

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container120 Amounts shown are per serving.

Thiamine

Interacts with
3 drugs
103 mg per serving

Thiamine (vitamin B1) is an essential nutrient your body needs to turn food into energy and to keep your nerves and heart healthy. Most people get eno...

Thiamine monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Stearic Acid, Hydroxypropyl Methylcellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Benfotiamine-V 150 mg by Benfotiamine.Net, Inc. Drug Interactions

Want to check YOUR meds against Benfotiamine-V 150 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

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3Drugs
3 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Benfotiamine-V 150 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Thiamine1 drug type · 3 drugs

Trimethoprim (Proloprim)

Trimethoprim might increase blood levels of thiamine.
In vitro, animal, and clinical research suggest that trimethoprim inhibits intestinal thiamine transporter ThTR-2, hepatic transporter OCT1, and renal transporters OCT2, MATE1, and MATE2, resulting in paradoxically increased thiamine plasma concentrations.

Likelihood Probable Evidence B
The maker

Brand information

Manufacturer and brand details for Benfotiamine-V 150 mg, from the product label.

Benfotiamine.Net, Inc.

See all Benfotiamine.Net, Inc. products
Name
Benfotiamine.Net, Inc.
Street Address
6586 Hypoluxo Rd., Ste 114
City
Lake Worth
State
FL
ZipCode
33467
Phone Number
1-888-493-8014
Web Address
http://www.benfotiamine.net
Pharmacist Counseling Corner

Benfotiamine-V 150 mg by Benfotiamine.Net, Inc.: Common Questions

Does Benfotiamine-V 150 mg by Benfotiamine.Net, Inc. interact with any medications?
Yes. Based on its ingredients, Benfotiamine-V 150 mg has a known interaction with 3 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Benfotiamine-V 150 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this really help diabetic nerve pain?
Benfotiamine is rated possibly effective for diabetic neuropathy based on available evidence. It's not a guaranteed fix, but some people do find it helpful. Your doctor can advise whether it's right for your situation.
What are the side effects?
In a 6-week clinical trial, a small number of people reported allergic skin reactions or mild stomach discomfort, but the rates were no different from placebo. Most people tolerate it well.
Is it safe if I'm pregnant or nursing?
There isn't enough safety data to know either way. Talk with your doctor or pharmacist about whether this product is right for you during pregnancy or while breastfeeding.
What exactly is benfotiamine?
Benfotiamine and S-benzoylithiamine-O-monophosphate are special forms of thiamine (vitamin B1) that are designed to be absorbed and used by your body more effectively than standard thiamine.
Will this interact with my blood pressure or diabetes medications?
No interactions are documented in our data for either benfotiamine or S-benzoylithiamine-O-monophosphate. Use the medication checker on this page or ask your pharmacist to verify your exact prescriptions.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Benfotiamine-V 150 mg label
Sources

Sources & How We Checked

Benfotiamine-V 150 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 8 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Thiamine 7 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
  3. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  4. Rogovik, A. L., Vohra, S., and Goldman, R. D. Safety considerations and potential interactions of vitamins: should vitamins be considered drugs? Ann.Pharmacother. 2010;44(2):311-324. PubMed
  5. Arruti N, Bernedo N, Audicana MT, Villarreal O, Uriel O, Muñoz D. Systemic allergic dermatitis caused by thiamine after iontophoresis. Contact Dermatitis. 2013 Dec;69(6):375-6. PubMed
  6. Thiamine hydrochloride injection package insert. Lake Zurich, IL: Fresenius Kabi, LLC; September 2019.
  7. Vora B, Wen A, Yee SW, et al. The Effect of Trimethoprim on Thiamine Absorption: A Transporter-Mediated Drug-Nutrient Interaction. Clin Pharmacol Ther 2023;114(2):381-392.

See these in context on the Thiamine monograph →

Benfotiamine 1 reference
  1. Stracke H, Gaus W, Achenbach U, Federlin K, Bretzel RG. Benfotiamine in diabetic polyneuropathy (BENDIP): results of a randomised, double blind, placebo-controlled clinical study. Exp Clin Endocrinol Diabetes 2008;116(10):600-5. PubMed

See these in context on the Benfotiamine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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