Berry Immune Booster Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Berry Immune Booster against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Berry Immune Booster is a dietary supplement by Mountain Meadow Kids with 4 active ingredients. Its ingredients are commonly taken for common cold, flu and respiratory infections, immune support.Based on those ingredients, 973 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Echinacea purpurea, Aronia, Elderberry. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Berry Immune Booster by Mountain Meadow Kids
Ask about any prescription or over-the-counter medication and we check it for interactions with Berry Immune Booster by Mountain Meadow Kids — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Berry Immune Booster by Mountain Meadow Kids
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Berry Immune Booster contains 4 ingredients total: a proprietary blend plus three active herbs — two types of echinacea (purpurea and angustifolia), elderberry, and aronia (also called chokeberry). The product is a liquid, made with glycerin and distilled water as inactive ingredients.
Echinacea has been traditionally used for immune support, elderberry is used similarly, and aronia is included for its antioxidant profile.
Does it work?
Not established
The evidence for what these ingredients actually do isn't established in our data. For both echinacea species, we hold ratings of insufficient reliable evidence for anxiety, athletic performance, ADHD, burns, chronic fatigue syndrome, and migraine headache.
Elderberry and aronia also show insufficient evidence for conditions like respiratory tract infections, cardiovascular disease, cognitive function, and others. In fact, aronia carries a rating of possibly ineffective for cardiovascular disease.
This doesn't mean the product doesn't work — it means the clinical studies we have aren't conclusive enough to make a claim either way.
How safe is it?
Well-documented data
Echinacea is generally well tolerated short-term, though some people report abdominal pain, constipation, diarrhea, heartburn, nausea, vomiting, or rashes. Rare but serious adverse effects include severe allergic reactions and hepatitis; people sensitive to ragweed or related plants (chrysanthemums, marigolds, daisies) are at higher risk for allergic reactions, including potentially severe ones like anaphylaxis.
Properly prepared elderberry seems well tolerated, but raw or unripe berries, seeds, leaves, and bark can be toxic. Safety data advises against using elderberry during pregnancy or while breastfeeding.
Aronia is well tolerated as a food, but supplement safety isn't well studied — about 14–53% of people in small studies reported gastrointestinal side effects like constipation, diarrhea, nausea, or stomach cramps when taking it as a concentrated juice.
Meds to double-check
Moderate interaction found
Check before taking if you're on drugs processed by your liver (cytochrome P450 3A4 or 1A2 substrates — ask your pharmacist which ones you take), immune-suppressing medications, blood thinners (anticoagulants or antiplatelet drugs like aspirin), diabetes medications, or caffeine-containing products. Echinacea may also interact with the cancer drug etoposide and HIV medications like lopinavir/ritonavir, and aronia may interact with the cancer drug trabectedin.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.
This product may appeal to parents looking for herbal immune support, but the evidence for whether it actually works isn't established in our data. If you take any prescription medications — especially blood thinners, diabetes drugs, immune-suppressing drugs, or drugs metabolized by your liver — talk with your pharmacist or doctor before starting.
People with ragweed allergies should be cautious due to echinacea's allergy risk. Avoid during pregnancy or breastfeeding.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 4 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 24, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Berry Immune Booster, straight from the product label.
| Brand | Mountain Meadow Kids |
|---|---|
| Barcode (UPC) | 813086016397 |
| Net contents | 2 Fluid Ounce(s); 60 mL |
| Market status | On market |
| Date entered into DSLD | Apr 24, 2025 |
| DSLD ID | 327810 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Children (All), Pregnant Women, Infants/Baby (0 - 1 Year) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Berry Immune Booster by Mountain Meadow Kids, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Blend | 1.25 mL | -- |
| Echinacea purpurea | 0 NP | -- |
| Echinacea angustifolia | 0 NP | -- |
| Elderberry | 0 NP | -- |
| Aronia | 0 NP | -- |
Other ingredients: Glycerin, Water, Distilled
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
1 dropperful=approx. 1/8 tsp.
The MMH Three-Leaf Promise: Our high-standards produce nothing less than pure, safe, and effective herbal products. You will always feel that we care - through our products, our service, and our understanding. We deliver on time.
FDA Disclaimer Statement
These statements have not evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Formula
Natural berry extracts
Formulation
Immune system support
Alcohol free GF (Gluten Free)
Vegan
Natural immune support Support a healthy immune system Use for year-round support
Alcohol-free
FDA Statement of Identity
Herbal Dietary Supplement
Seals/Symbols
Made in Montana USA
Suggested/Recommended/Usage/Directions
Suggested use: 5 drops - 1/4 tsp. Take 1-3 times daily or as needed. See catalog for dosage information. Shake well.
Precautions
Caution: If you are pregnant, nursing, have a medical condition, or are taking a prescription, consult your health care provider before using this product.
Keep out of reach of children.
Storage
Store in a cool, dry place out of sunlight.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Berry Immune Booster by Mountain Meadow Kids label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Berry Immune Booster by Mountain Meadow Kids
These are the 4 active ingredients this product is made of. Select any to open its full monograph.
Serving size0.25 tsp Dosage formLiquid Servings per container48 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Blend
Other (inactive) ingredients: Glycerin, Water, Distilled. These complete the product’s ingredient list but are not active constituents.
Berry Immune Booster by Mountain Meadow Kids Drug Interactions
HelloPharmacist Interaction Report
Berry Immune Booster by Mountain Meadow Kids contains echinacea and aronia (chokeberry), both of which interact with multiple medications.
The most serious interaction is with echinacea's effect on drugs processed by your liver's enzyme systems. These enzymes (cytochrome P450) break down many medications — echinacea can both speed up and slow down this process, which may make your drugs less effective or cause them to build up to unsafe levels.
Both echinacea species in this product also have moderate interactions with drugs that suppress your immune system; since echinacea stimulates immunity, it could interfere with how these medications work.
Read the full breakdown — every affected drug type, severity by severity
The product's echinacea can also increase caffeine levels by about 30%, which might cause jitteriness or sleep problems if you drink coffee or take caffeine-containing medications. Additionally, aronia (chokeberry) may increase bleeding risk if you take blood thinners (anticoagulants) or blood-thinning pain relievers (antiplatelet drugs), and may affect blood sugar levels if you're on diabetes medications.
Theoretically, aronia could also increase levels of certain cancer drugs.
Echinacea has minor interactions with blood thinners like warfarin and some HIV medications, though the clinical significance isn't always clear. Altogether, these interactions span 959 individual medications.
Before you start this product, check your exact medications with the tool on this page — especially if you take any prescription drugs, blood thinners, diabetes medications, or immune-suppressing drugs.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Berry Immune Booster?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Berry Immune Booster interact with 973 drugs. Click any drug to see the details.
3 of the 4 ingredients in Berry Immune Booster interact with drugs. Each result below shows which ingredient is responsible. Echinacea purpurea Aronia Elderberry
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Berry Immune Booster — through 2 ingredients. Tap an ingredient for the detail:
Echinacea AngustifoliaImmunosuppressants Moderate
Interaction Summary
Echinacea has immunostimulant activity which may interfere with immunosuppressant therapy.
Read the full Echinacea Angustifolia + 6-mercaptopurine interactionElderberryImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry + 6-mercaptopurine interactionAdo-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Berry Immune Booster — through 2 ingredients. Tap an ingredient for the detail:
Echinacea AngustifoliaCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Echinacea may induce hepatic CYP3A4 and inhibit intestinal CYP3A4.
Read the full Echinacea Angustifolia + Ado-trastuzumab Emtansine interactionAroniaCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, chokeberry might increase levels of drugs metabolized by CYP3A4.
Read the full Aronia + Ado-trastuzumab Emtansine interactionAbciximabReoPro
How Abciximab interacts with Berry Immune Booster — through 1 ingredient. Tap an ingredient for the detail:
AroniaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chokeberry might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aronia + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Berry Immune Booster — through 2 ingredients. Tap an ingredient for the detail:
AroniaCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, chokeberry might increase levels of drugs metabolized by CYP3A4.
Read the full Aronia + Abemaciclib interactionEchinacea AngustifoliaCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Echinacea may induce hepatic CYP3A4 and inhibit intestinal CYP3A4.
Read the full Echinacea Angustifolia + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Berry Immune Booster — through 2 ingredients. Tap an ingredient for the detail:
AroniaCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, chokeberry might increase levels of drugs metabolized by CYP3A4.
Read the full Aronia + Abiraterone interactionEchinacea AngustifoliaCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Echinacea may induce hepatic CYP3A4 and inhibit intestinal CYP3A4.
Read the full Echinacea Angustifolia + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Berry Immune Booster — through 2 ingredients. Tap an ingredient for the detail:
AroniaCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, chokeberry might increase levels of drugs metabolized by CYP3A4.
Read the full Aronia + Abiraterone Acetate interactionEchinacea AngustifoliaCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Echinacea may induce hepatic CYP3A4 and inhibit intestinal CYP3A4.
Read the full Echinacea Angustifolia + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Berry Immune Booster — through 3 ingredients. Tap an ingredient for the detail:
Echinacea AngustifoliaImmunosuppressants Moderate
Interaction Summary
Echinacea has immunostimulant activity which may interfere with immunosuppressant therapy.
Read the full Echinacea Angustifolia + Abrocitinib interactionElderberryImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry + Abrocitinib interactionAroniaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chokeberry might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aronia + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Berry Immune Booster — through 2 ingredients. Tap an ingredient for the detail:
Echinacea AngustifoliaCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Echinacea may induce hepatic CYP3A4 and inhibit intestinal CYP3A4.
Read the full Echinacea Angustifolia + Acalabrutinib interactionAroniaCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, chokeberry might increase levels of drugs metabolized by CYP3A4.
Read the full Aronia + Acalabrutinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Berry Immune Booster — through 1 ingredient. Tap an ingredient for the detail:
AroniaAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chokeberry might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Aronia + Acarbose interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Berry Immune Booster — through 1 ingredient. Tap an ingredient for the detail:
AroniaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chokeberry might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aronia + Acenocoumarol interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Berry Immune Booster — through 1 ingredient. Tap an ingredient for the detail:
Echinacea AngustifoliaCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Echinacea might inhibit the metabolism of CYP1A2 and increase plasma levels of some drugs.
Read the full Echinacea Angustifolia + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Berry Immune Booster — through 2 ingredients. Tap an ingredient for the detail:
Echinacea AngustifoliaCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Echinacea might inhibit the metabolism of CYP1A2 and increase plasma levels of some drugs.
Read the full Echinacea Angustifolia + Acetaminophen, Aspirin interactionAroniaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chokeberry might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aronia + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Berry Immune Booster — through 2 ingredients. Tap an ingredient for the detail:
AroniaAnticoagulant/antiplatelet Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, chokeberry might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aronia + Acetaminophen, Aspirin, Caffeine interactionEchinacea AngustifoliaCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Echinacea might inhibit the metabolism of CYP1A2 and increase plasma levels of some drugs.
Read the full Echinacea Angustifolia + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Berry Immune Booster — through 1 ingredient. Tap an ingredient for the detail:
Echinacea AngustifoliaCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Echinacea might inhibit the metabolism of CYP1A2 and increase plasma levels of some drugs.
Read the full Echinacea Angustifolia + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Berry Immune Booster — through 1 ingredient. Tap an ingredient for the detail:
Echinacea AngustifoliaCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Echinacea might inhibit the metabolism of CYP1A2 and increase plasma levels of some drugs.
Read the full Echinacea Angustifolia + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Berry Immune Booster — through 2 ingredients. Tap an ingredient for the detail:
Echinacea AngustifoliaCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Echinacea might inhibit the metabolism of CYP1A2 and increase plasma levels of some drugs.
Read the full Echinacea Angustifolia + Acetaminophen, Butalbital, Caffeine interactionAroniaCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, chokeberry might increase levels of drugs metabolized by CYP3A4.
Read the full Aronia + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Berry Immune Booster — through 2 ingredients. Tap an ingredient for the detail:
Echinacea AngustifoliaCaffeine, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Echinacea can increase plasma levels of caffeine by inhibiting its metabolism.
Read the full Echinacea Angustifolia + Acetaminophen, Butalbital, Caffeine, Codeine interactionAroniaCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, chokeberry might increase levels of drugs metabolized by CYP3A4.
Read the full Aronia + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Berry Immune Booster — through 1 ingredient. Tap an ingredient for the detail:
Echinacea AngustifoliaCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Echinacea might inhibit the metabolism of CYP1A2 and increase plasma levels of some drugs.
Read the full Echinacea Angustifolia + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Berry Immune Booster — through 1 ingredient. Tap an ingredient for the detail:
Echinacea AngustifoliaCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Echinacea might inhibit the metabolism of CYP1A2 and increase plasma levels of some drugs.
Read the full Echinacea Angustifolia + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Berry Immune Booster — through 2 ingredients. Tap an ingredient for the detail:
Echinacea AngustifoliaCytochrome P450 1a2 (cyp1a2) Substrates, Caffeine +1 Moderate
Interaction Summary
Echinacea might inhibit the metabolism of CYP1A2 and increase plasma levels of some drugs.
Read the full Echinacea Angustifolia + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAroniaCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, chokeberry might increase levels of drugs metabolized by CYP3A4.
Read the full Aronia + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Berry Immune Booster — through 2 ingredients. Tap an ingredient for the detail:
Echinacea AngustifoliaCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Echinacea may induce hepatic CYP3A4 and inhibit intestinal CYP3A4.
Read the full Echinacea Angustifolia + Acetaminophen, Caffeine, Codeine interactionAroniaCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, chokeberry might increase levels of drugs metabolized by CYP3A4.
Read the full Aronia + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Berry Immune Booster — through 2 ingredients. Tap an ingredient for the detail:
Echinacea AngustifoliaCaffeine, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Echinacea can increase plasma levels of caffeine by inhibiting its metabolism.
Read the full Echinacea Angustifolia + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAroniaCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, chokeberry might increase levels of drugs metabolized by CYP3A4.
Read the full Aronia + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Berry Immune Booster — through 2 ingredients. Tap an ingredient for the detail:
Echinacea AngustifoliaCytochrome P450 1a2 (cyp1a2) Substrates, Caffeine +1 Moderate
Interaction Summary
Echinacea might inhibit the metabolism of CYP1A2 and increase plasma levels of some drugs.
Read the full Echinacea Angustifolia + Acetaminophen, Caffeine, Dihydrocodeine interactionAroniaCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, chokeberry might increase levels of drugs metabolized by CYP3A4.
Read the full Aronia + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Berry Immune Booster — through 2 ingredients. Tap an ingredient for the detail:
Echinacea AngustifoliaCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Echinacea may induce hepatic CYP3A4 and inhibit intestinal CYP3A4.
Read the full Echinacea Angustifolia + Acetaminophen, Caffeine, Isometheptene interactionAroniaCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, chokeberry might increase levels of drugs metabolized by CYP3A4.
Read the full Aronia + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Berry Immune Booster — through 2 ingredients. Tap an ingredient for the detail:
Echinacea AngustifoliaCaffeine, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Echinacea can increase plasma levels of caffeine by inhibiting its metabolism.
Read the full Echinacea Angustifolia + Acetaminophen, Caffeine, Pyrilamine interactionAroniaCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, chokeberry might increase levels of drugs metabolized by CYP3A4.
Read the full Aronia + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Berry Immune Booster — through 2 ingredients. Tap an ingredient for the detail:
Echinacea AngustifoliaCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Echinacea might inhibit the metabolism of CYP1A2 and increase plasma levels of some drugs.
Read the full Echinacea Angustifolia + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAroniaCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, chokeberry might increase levels of drugs metabolized by CYP3A4.
Read the full Aronia + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Berry Immune Booster — through 2 ingredients. Tap an ingredient for the detail:
AroniaCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, chokeberry might increase levels of drugs metabolized by CYP3A4.
Read the full Aronia + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionEchinacea AngustifoliaCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Echinacea might inhibit the metabolism of CYP1A2 and increase plasma levels of some drugs.
Read the full Echinacea Angustifolia + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Berry Immune Booster — through 2 ingredients. Tap an ingredient for the detail:
Echinacea AngustifoliaCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Echinacea might inhibit the metabolism of CYP1A2 and increase plasma levels of some drugs.
Read the full Echinacea Angustifolia + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAroniaCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, chokeberry might increase levels of drugs metabolized by CYP3A4.
Read the full Aronia + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Berry Immune Booster — through 2 ingredients. Tap an ingredient for the detail:
Echinacea AngustifoliaCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Echinacea may induce hepatic CYP3A4 and inhibit intestinal CYP3A4.
Read the full Echinacea Angustifolia + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAroniaCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, chokeberry might increase levels of drugs metabolized by CYP3A4.
Read the full Aronia + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Berry Immune Booster — through 2 ingredients. Tap an ingredient for the detail:
Echinacea AngustifoliaCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Echinacea may induce hepatic CYP3A4 and inhibit intestinal CYP3A4.
Read the full Echinacea Angustifolia + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAroniaCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, chokeberry might increase levels of drugs metabolized by CYP3A4.
Read the full Aronia + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Berry Immune Booster with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Echinacea purpurea
Caffeine
Echinacea can increase plasma levels of caffeine by inhibiting its metabolism.
Echinacea seems to increase plasma concentrations of caffeine by around 30%. This is likely due to inhibition of cytochrome P450 1A2 (CYP1A2) by echinacea.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Echinacea might inhibit the metabolism of CYP1A2 and increase plasma levels of some drugs.
Echinacea appears to inhibit CYP1A2 enzymes in humans. Additionally, echinacea seems to increase plasma concentrations of caffeine, a CYP1A2 substrate, by around 30%. Theoretically, echinacea might increase levels of other drugs metabolized by CYP1A2.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Echinacea may induce hepatic CYP3A4 and inhibit intestinal CYP3A4. This may increase or decrease levels of drugs metabolized by CYP3A4.
Several clinical trials have shown that taking echinacea for up to one month does not significantly affect the metabolism of various CYP3A4 substrates, including midazolam, docetaxel, etravirine, lopinavir-ritonavir, and darunavir-ritonavir. However, other clinical research shows that echinacea may increase the clearance of midazolam, suggesting that echinacea might induce CYP3A4. The discrepancy is thought to be due to differing effects of echinacea on intestinal versus hepatic CYP3A4 enzymes. Echinacea appears to induce hepatic CYP3A4 but inhibit intestinal CYP3A4. In some cases, these effects might cancel each other out, but in others, drug levels may be increased or decreased depending on the level of effect at hepatic and intestinal sites. The effect of echinacea on CYP3A4 activity may differ depending on the CYP3A4 substrate.
Etoposide (Vepesid)
Echinacea may increase levels of etoposide.
In one report, concomitant use of etoposide and echinacea was associated with more severe thrombocytopenia than the use of etoposide alone, suggesting inhibition of etoposide metabolism. Etoposide is a cytochrome P450 3A4 (CYP3A4) substrate. Echinacea has variable effects on CYP3A4, but some studies have reported inhibition of the enzyme.
Immunosuppressants
Echinacea has immunostimulant activity which may interfere with immunosuppressant therapy.
Theoretically, echinacea may interfere with immunosuppressant therapy because of its immunostimulant activity.
Darunavir (Prezista)
Theoretically, echinacea may interfere with the metabolism of darunavir; however, a small clinical study found no effect.
Darunavir is metabolized by cytochrome P450 3A4 (CYP3A4) and is administered with the CYP3A4 inhibitor ritonavir to increase its plasma concentrations. Echinacea has variable effects on CYP3A4, but administration of an E. purpurea root extract (Arkocapsulas Echinacea, Arkopharma) 500 mg four times daily for 14 days did not affect darunavir/ritonavir pharmacokinetics in 15 HIV-infected patients.
Dayquil Severe
Echinacea is reported to have varying effects on a number of Cytochrome P450 metabolizing enzymes in the liver, including CYP1A2 and CYP3A4, which play a role in acetaminophen and dextromethorphan metabolism (both contained in DayQuil Severe), respectively. Studies have reported both enzyme inhibition and induction, making it difficult to predict clinically significant drug interactions with reliability. Specific drug interaction studies reporting definitive results are rare, and potential drug interactions involving echinacea should likely be taken on a case-by-case basis. Based on what we know about how acetaminophen and dextromethorphan are metabolized, the risk of a clinically significant interaction between echinacea and DayQuil Severe is low.
Docetaxel (Taxotere)
Theoretically, echinacea may interfere with the metabolism of docetaxel; however, a small clinical study found no effect.
Docetaxel is metabolized by cytochrome P450 3A4 (CYP3A4). Echinacea has variable effects on CYP3A4, but taking E. purpurea whole plant extract (Echinaforce, A. Vogel Biopharma AG) 20 drops three times daily for 2 weeks did not alter the pharmacokinetics of docetaxel in one clinical study.
Etravirine (Intelence)
Theoretically, echinacea may interfere with the metabolism of etravirine; however, a small clinical study found no effect.
Etravirine is metabolized by cytochrome P450 3A4 (CYP3A4). Echinacea has variable effects on CYP3A4, but taking E. purpurea root extract (Arkocapsulas Echinacea, Arkopharma) 500 mg three times daily for 14 days did not alter the pharmacokinetics of etravirine in HIV-infected patients.
Lopinavir/Ritonavir (Kaletra)
Theoretically, echinacea may interfere with the metabolism of lopinavir; however, a small clinical study found no effect.
Lopinavir is metabolized by cytochrome P450 3A4 (CYP3A4) and is administered with the CYP3A4 inhibitor ritonavir to increase its plasma concentrations. Echinacea has variable effects on CYP3A4, but taking E. purpurea (Echinamide, Natural Factors Nutritional Products, Inc.) 500 mg three times daily for 14 days did not alter the pharmacokinetics of lopinavir/ritonavir in healthy volunteers.
Midazolam (Versed)
Theoretically, echinacea may increase the metabolism of intravenous midazolam.
Echinacea induces hepatic CYP3A4 and might decrease plasma levels of midazolam by about 20%, reducing the effectiveness of intravenous midazolam. Echinacea also appears to inhibit intestinal CYP3A4, which could theoretically increase the bioavailability of oral midazolam. This may cancel out the decrease in availability caused by induction of hepatic CYP3A4, such that overall plasma levels after oral administration of midazolam are not affected by echinacea.
Warfarin (Coumadin)
Echinacea seems to increase the clearance of warfarin, although the effect may not be clinically significant.
Preliminary clinical research in healthy male volunteers suggests that taking echinacea increases the clearance of the active S-isomer of warfarin after a single dose of warfarin, but there was not a clinically significant effect on the INR.
Aronia
Anticoagulant/Antiplatelet Drugs
Theoretically, chokeberry might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Clinical and in vitro research suggests that chokeberry extract can temporarily inhibit platelet aggregation and decrease clot formation.
Antidiabetes Drugs
Theoretically, chokeberry might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Some clinical research shows that chokeberry decreases levels of blood glucose in some patients with diabetes. However, other clinical research suggests that chokeberry has no significant effect on blood glucose levels.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, chokeberry might increase levels of drugs metabolized by CYP3A4.
In vitro research shows that chokeberry inhibits CYP3A4. In humans, there is one case report of a drug interaction with trabectedin, a CYP3A4 substrate, which is hypothesized to have been caused by chokeberry inhibition of CYP3A4.
Trabectedin (Yondelis)
Theoretically, chokeberry might increase the effects and adverse effects of trabectedin.
In one case report, a patient drinking chokeberry juice developed rhabdomyolysis induced by trabectedin, a cytochrome P450 3A4 (CYP3A4) substrate. It is possible that inhibition of CYP3A4 by chokeberry juice might have inhibited the metabolism of trabectedin and increased trabectedin levels in this patient.
Elderberry
Immunosuppressants
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Elderberry has immunostimulant activity, increasing the production of cytokines, including interleukin and tumor necrosis factor.
Pazopanib (Votrient)
Theoretically, elderberry might interact with pazopanib, potentially increasing the risk of adverse effects.
Brand information
Manufacturer and brand details for Berry Immune Booster, from the product label.
Mountain Meadow Kids
See all Mountain Meadow Kids products- Name
- Mountain Meadow Herbs, Inc.
- Street Address
- 1019 Hard Rock Rd
- City
- Somers
- State
- MT
- ZipCode
- 59932
- Phone Number
- 888.528.8615
- Web Address
- www.mmherbs.com
Berry Immune Booster by Mountain Meadow Kids: Common Questions
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Berry Immune Booster’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Echinacea
Interacts with 816 drugsEchinacea is a popular herb taken to help prevent or shorten the common cold, but study results are mixed and the overall benefit appears small at best. It is generally well tolerated for sh...
Read the full Echinacea monograph → Herb & supplement monographElderberry
Interacts with 121 drugsElderberry is a popular herbal supplement, mainly taken to help with colds and flu. Some small studies suggest it may modestly shorten cold or flu symptoms, but the evidence is limited and n...
Read the full Elderberry monograph → Herb & supplement monographChokeberry
Interacts with 811 drugsChokeberry (aronia) is a dark berry rich in antioxidants called polyphenols, and it's widely eaten as juice, jam, and supplements. Early research hints it may support heart health, blood pre...
Read the full Chokeberry monograph →Sources & How We Checked
Berry Immune Booster's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 65 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Echinacea 51 references
- Mullins RJ. Echinacea-associated anaphylaxis. Med J Aust 1998;168:170-1. PubMed
- Mullins RJ. Allergic reactions to Echinacea. J Allergy Clin Immunol 2000;104:S340-341 (Abstract 1003).
- Chavez ML, Chavez PI. Echinacea. Hosp Pharm 1998;33:180-8.
- Grimm W, Muller HH. A randomized controlled trial of the effect of fluid extract of Echinacea purpurea on the incidence and severity of colds and respiratory infections. Am J Med 1999;106:138-43. PubMed
- Taylor JA, Weber W, Standish L, et al. Efficacy and safety of echinacea in treating upper respiratory tract infections in children: a randomized controlled trial. JAMA 2003;290:2824-30.. PubMed
- Luettig B, Steinmuller C, Gifford GE, et al. Macrophage activation by the polysaccharide arabinogalactan isolated from plant cell cultures of Echinacea purpurea. J Natl Cancer Inst 1989;81:669-75. PubMed
- Stimpel M, Proksch A, Wagner H, et al. Macrophage activation and induction of macrophage cytotoxicity by purified polysaccharide fractions from the plant Echinacea purpurea. Infect Immun 1984;46:845-9. PubMed
- Budzinski JW, Foster BC, Vandenhoek S, Arnason JT. An in vitro evaluation of human cytochrome P450 3A4 inhibition by selected commercial herbal extracts and tinctures. Phytomedicine 2000;7:273-82. PubMed
- Gallo M, Sarkar M, Au W, et al. Pregnancy outcome following gestational exposure to echinacea: A prospective controlled study. Arch Intern Med 2000;160:3141-3. PubMed
- Soon SL, Crawford RI. Recurrent erythema nodosum associated with echinacea herbal therapy. J Am Acad Dermatol 2001;44:298-9. PubMed
- Mullins RJ, Heddle R. Adverse reactions associated with echinacea: the Australian experience. Ann Allergy Asthma Immunol 2002;88:42-51. PubMed
- Logan JL, Ahmed J. Critical hypokalemic renal tubular acidosis due to Sjogren's syndrome: association with the purported immune stimulant echinacea. Clin Rheumatol 2003;22:158-9.
- Schulten B, Bulitta M, Ballering-Bruhl B, et al. Efficacy of Echinacea purpurea in patients with a common cold. A placebo-controlled, randomised, double-blind clinical trial. Arzneimittelforschung 2001;51:563-8.. PubMed
- Yale SH, Glurich I. Analysis of the inhibitory potential of Ginkgo biloba, Echinacea purpurea, and Serenoa repens on the metabolic activity of cytochrome P450 3A4, 2D6, and 2C9. J Altern Complement Med 2005;11:433-9.
- Yale SH, Liu K. Echinacea purpurea therapy for the treatment of the common cold: a randomized, double-blind, placebo-controlled clinical trial. Arch Intern Med 2004;164:1237-41. PubMed
- Gorski JC, Huang S, Zaheer NA, et al. The effect of echinacea (Echinacea purpurea root) on cytochrome P450 activity in vivo.Clin Pharmacol Ther 2003;73 (Abstract PDII-A-8):P94. PubMed
- Lee AN, Werth VP. Activation of autoimmunity following use of immunostimulatory herbal supplements. Arch Dermatol 2004;140:723-7. PubMed
- Goel V, Lovlin R, Barton R, et al. Efficacy of a standardized echinacea preparation (Echinilin) for the treatment of the common cold: a randomized, double-blind, placebo-controlled trial. J Clin Pharm Ther 2004;29:75-83.
- Barrett B. Medicinal properties of Echinacea: a critical review. Phytomedicine 2003;10:66-86. PubMed
- Huntley AL, Thompson Coon J, Ernst E. The safety of herbal medicinal products derived from Echinacea species: a systematic review. Drug Saf 2005;28:387-400. PubMed
- Turner RB, Bauer R, Woelkart K, et al. An evaluation of Echinacea angustifolia in experimental rhinovirus infections. N Engl J Med 2005;353:341-8.
- Gurley BJ, Gardner SF, Hubbard MA, et al. In vivo assessment of botanical supplementation on human cytochrome P450 phenotypes: Citrus aurantium, Echinacea purpurea, milk thistle, and saw palmetto. Clin Pharmacol Ther 2004;76:428-40. .
- Perri D, Dugoua JJ, Mills E, Koren G. Safety and efficacy of echinacea (Echinacea augustafolia, e. purpurea and e. pallida) during pregnancy and lactation. Can J Clin Pharmacol 2006;13:e262-7.
- Kocaman O, Hulagu S, Senturk O. Echinacea-induced severe acute hepatitis with features of cholestatic autoimmune hepatitis. Eur J Intern Med 2008;19:148. PubMed
- Barrett B, Brown R, Rakel D. et al. Echinacea for treating the common cold: a randomized trial. Ann Intern Med 2010;153:769-77. PubMed
- Press Release: Echinacea herbal products should not be used in children under 12 years old. Medicines and Healthcare Products Regulatory Agency (UK). August 20, 2012. Available at: www.mhra.gov.uk/NewsCentre/Pressreleases/CON180627. (Accessed 21 October
- Barrett B, Brown R, Rakel D, Rabago D, et al. Placebo effects and the common cold: a randomized controlled trial. Ann.Fam.Med 2011;9:312-22. PubMed
- Haller J, Freund, TF, Pelczer, KG, et al. The anxiolytic potential and psychotropic side effects of an echinacea preparation in laboratory animals and healthy volunteers. Phytother.Res. 2013;27:54-61.
- Grbic J, Wexler I, Celenti R, et al. A phase II trial of a transmucosal herbal patch for the treatment of gingivitis. J Am Dent.Assoc. 2011;142:1168-75. PubMed
- Schapowal A, Berger D, Klein P, et al. Echinacea/sage or chlorhexidine/lidocaine for treating acute sore throats: a randomized double-blind trial. Eur.J Med Res 9-1-2009;14:406-12. PubMed
- Bossaer JB and Odle BL. Probable etoposide interaction with Echinacea. J.Diet.Suppl 2012;9:90-5.
- Abdul MI, Jiang X, Williams KM, et al. Pharmacokinetic and pharmacodynamic interactions of echinacea and policosanol with warfarin in healthy subjects. Br J Clin.Pharmacol. 2010;69:508-15. PubMed
- Kemp, D. E. and Franco, K. N. Possible leukopenia associated with long-term use of echinacea. J Am Board Fam.Pract. 2002;15(5):417-419.
- Liatsos, G., Elefsiniotis, I., Todorova, R., and Moulakakis, A. Severe thrombotic thrombocytopenic purpura (TTP) induced or exacerbated by the immunostimulatory herb Echinacea. Am J Hematol. 2006;81(3):224.
- Penzak, S. R., Robertson, S. M., Hunt, J. D., Chairez, C., Malati, C. Y., Alfaro, R. M., Stevenson, J. M., and Kovacs, J. A. Echinacea purpurea significantly induces cytochrome P450 3A activity but does not alter lopinavir-ritonavir exposure in healthy s
- Maskatia, Z. K. and Baker, K. Hypereosinophilia associated with echinacea use. South.Med J 2010;103(11):1173-1174. PubMed
- Parnham MJ. Benefit-risk assessment of the squeezed sap of the purple coneflower (Echinacea purpurea) for long-term oral immunostimulation. Phytomed 1996;3:95-102. PubMed
- Schroder-Aasen T, Molden G, Nilsen OG. In vitro inhibition of CYP3A4 by the multiherbal commercial product Sambucus Force and its main constituents Echinacea purpurea and Sambucus nigra. Phytother Res 2012;26(11):1606-13.
- Moltó J, Valle M, Miranda C, et al. Herb-drug interaction between Echinacea purpurea and darunavir-ritonavir in HIV-infected patients. Antimicrob Agents Chemother 2011;55(1):326-30.
- Goey AK, Meijerman I, Rosing H, et al. The effect of Echinacea purpurea on the pharmacokinetics of docetaxel. Br J Clin Pharmacol 2013;76(3):467-74.
- Moltó J, Valle M, Miranda C, et al. Herb-drug interaction between Echinacea purpurea and etravirine in HIV-infected patients. Antimicrob Agents Chemother 2012;56(10):5328-31. PubMed
- Lawrenson JA, Walls T, Day AS. Echinacea-induced acute liver failure in a child. J Paediatr Child Health 2014;50(10):841.
- Hansen TS, Nilsen OG. In vitro CYP3A4 metabolism: inhibition by Echinacea purpurea and choice of substrate for the evaluation of herbal inhibition. Basic Clin Pharmacol Toxicol 2008;103:445-9.
- Gabranis I, Koufakis T1, Papakrivos I, Batala S. Echinacea-associated acute cholestatic hepatitis. J Postgrad Med. 2015;61(3):211-2. PubMed
- Jalloh MA, Gregory PJ, Hein D, et al. Dietary supplement interactions with antiretrovirals: a systematic review. Int J STD AIDS. 2017 Jan;28(1):4-15. PubMed
- Karsch-Völk M, Barrett B, Kiefer D, Bauer R, Ardjomand-Woelkart K, Linde K. Echinacea for preventing and treating the common cold. Cochrane Database Syst Rev.2014;(2):CD000530. doi: 10.1002/14651858.CD000530.pub3. PubMed
- Hoban CL, Byard RW, Musgrave IF. Analysis of spontaneous adverse drug reactions to echinacea, valerian, black cohosh and ginkgo in Australia from 2000 to 2015. J Integr Med. 2019;17(5):338-343. PubMed
- Ogal M, Johnston SL, Klein P, Schoop R. Echinacea reduces antibiotic usage in children through respiratory tract infection prevention: a randomized, blinded, controlled clinical trial. Eur J Med Res. 2021 Apr 8;26(1):33. PubMed
- Lopresti AL, Smith SJ. An investigation into the anxiety-relieving and mood-enhancing effects of Echinacea angustifolia (EP107 ™): A randomised, double-blind, placebo-controlled study. J Affect Disord 2021;293:229-237.
- Weishaupt R, Buchkov A, Kolev E, Klein P, Schoop R. Reduction of viral load in patients with acute sore throats: Results from an observational clinical trial with Echinacea / Salvia lozenges [published online ahead of print, 2023 Mar 8]. Complement Med Re
- Sumer J, Keckeis K, Scanferla G, et al. Novel Echinacea formulations for the treatment of acute respiratory tract infections in adults-A randomized blinded controlled trial. Front Med (Lausanne) 2023;10:948787. PubMed
Elderberry 6 references
- Barak V, Halperin T, Kalickman I. The effect of Sambucol, a black elderberry-based, natural product, on the production of human cytokines: I. Inflammatory cytokines. Eur Cytokine Netw 2001;12:290-6..
- Elderberry (Sambucus species). The Poison Plant Patch, Novia Scotia Museum, 2007. Available at: http://museum.gov.ns.ca/poison/?section=species&id=117 (Accessed 16 October 2009).
- European elder. Canadian Poisonous Plants Information System. Available at: http://www.cbif.gc.ca/pls/pp/ppack.jump?p_null=all&p_psn=121&p_type=all&p_sci=comm&p_x=px (Accessed 16 October 2009).
- Raus K, Pleschka S, Klein P, Schoop R, Fisher P. Effect of an echinacea-based hot drink versus oseltamivir in Influenza treatment: a randomized, double-blind, double-dummy, multicenter, noninferiority clinical trial. . Curr Ther Res Clin Exp. 2015;20;77:6 PubMed
- Ramachandran A, Antala D, Pudasainee P, Panginikkod S, Gupta H. A Plausible Association Between the Use of Elderberry and Autoimmune Hepatitis. Cureus 2022;14(4):e24250. PubMed
- Agarwal N, Mangla A. Elderberry interaction with pazopanib in a patient with soft-tissue sarcoma: A case report and literature review. Mol Clin Oncol 2024;20(5):36. PubMed
Chokeberry 8 references
- Sikora J, Broncel M, Markowicz M, Chalubinski M, Wojdan K, Mikiciuk-Olasik E. Short-term supplementation with Aronia melanocarpa extract improves platelet aggregation, clotting, and fibrinolysis in patients with metabolic syndrome. Eur J Nutr. 2012 Aug;51 PubMed
- Simeonov SB, Botushanov NP, Karahanian EB, Pavlova MB, Husianitis HK, Troev DM. Effects of Aronia melanocarpa juice as part of the dietary regimen in patients with diabetes mellitus. Folia Med (Plovdiv). 2002;44(3):20-3.
- Savikin K, Menkovic N, Zdunic G, Pljevljakusic D, Spasic S, Kardum N, Konic-Ristic A. Dietary supplementation with polyphenol-rich chokeberry juice improves skin morphology in cellulite. J Med Food. 2014 May;17(5):582-7. PubMed
- Bräunlich M, Christensen H, Johannesen S, Slimestad R, Wangensteen H, Malterud KE, Barsett H. In vitro inhibition of cytochrome P450 3A4 by Aronia melanocarpa constituents. Planta Med. 2013 Jan;79(2):137-41. PubMed
- Strippoli S, Lorusso V, Albano A, Guida M. Herbal-drug interaction induced rhabdomyolysis in a liposarcoma patient receiving trabectedin. BMC Complement Altern Med. 2013 Jul 30;13:199. PubMed
- Ryszawa N, Kawczynska-Drózdz A, Pryjma J, Czesnikiewicz-Guzik M, Adamek-Guzik T, Naruszewicz M, Korbut R, Guzik TJ. Effects of novel plant antioxidants on platelet superoxide production and aggregation in atherosclerosis. J Physiol Pharmacol. 2006 Dec;57(
- Milutinovic M, Velickovic Radovanovic R, Savikin K, et al. Chokeberry juice supplementation in type 2 diabetic patients - impact on health status. J Appl Biomed 2019;17(4):218-224. PubMed
- Lackner S, Sconocchia T, Ziegler T, et al. Immunomodulatory effects of aronia juice polyphenols-results of a randomized placebo-controlled human intervention study and cell culture experiments. Antioxidants (Basel) 2022;11(7):1283. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC