No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Beta-Sitosterol Ingredients & Drug Interactions

by Vitabase

Beta-Sitosterol label
See full label image
Capsule Category: Non-nutrient/non-botanical
No known interaction
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Beta-Sitosterol against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line No known interaction

Beta-Sitosterol is a dietary supplement by Vitabase with 1 active ingredient. Its ingredients are commonly taken for high cholesterol, enlarged prostate (bph), heart health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

Jump to a section

HelloPharmacist Scorecard of Beta-Sitosterol by Vitabase

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: Beta-Sitosterol Complex, a plant sterol that your body uses to help manage cholesterol and prostate health. The capsule itself is made from gelatin, with microcrystalline cellulose and magnesium stearate added as inactive ingredients to hold it together and keep it stable.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Prostate health support.
  • We looked for evidence on: Benign prostatic hyperplasia (BPH), Chronic prostatitis and chronic pelvic pain syndrome (CP/CPPS), Prostate function, Urinary flow.
  • The strongest evidence on file: Beta-sitosterol is rated "Likely Effective" for Benign prostatic hyperplasia (BPH) (Natural Medicines).
  • Also on file: Beta-sitosterol is rated "Insufficient Reliable Evidence To Rate" for Chronic prostatitis and chronic pelvic pain syndrome (CP/CPPS).

Beta-sitosterol is likely effective for benign prostatic hyperplasia (BPH) — the non-cancerous enlargement of the prostate that can cause urinary symptoms. For lowering cholesterol in familial hypercholesterolemia (an inherited condition that raises blood cholesterol) and for reducing the risk of coronary heart disease, the evidence shows it's possibly effective.

If you're taking it for prostate symptoms or cholesterol, it may help, but results vary from person to person.

The evidence, ingredient by ingredient Beta-sitosterol

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Beta-sitosterol is generally well tolerated when taken by mouth for short periods. The most common side effects are mild digestive issues — constipation, diarrhea, gas, indigestion, and nausea.

A small number of people have reported reduced appetite. There is one case report of acute inflammation of the pancreas (pancreatitis) that started on the first day of use in a 57-year-old; the symptoms went away when he stopped.

Beta-sitosterol may also worsen acne in some people, especially when taken alone. There isn't enough safety data to know whether it's safe during pregnancy or breastfeeding, so the safety data advises against supplemental use in both.

If you're pregnant, planning pregnancy, or breastfeeding, talk with your doctor or pharmacist before taking this.

Side effects, ingredient by ingredient Beta-sitosterol

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for beta-sitosterol with the medications we could check. Run your own drugs through the tool on this page to confirm, and ask your doctor or pharmacist if you're unsure about any specific medication.

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Vitabase Beta-Sitosterol is a single-ingredient supplement that may help with prostate symptoms or cholesterol management, with mild digestive side effects in some users. If you have a history of pancreatitis, acne, or digestive problems, mention this supplement to your doctor or pharmacist first.

Pregnant or breastfeeding people should skip it unless their healthcare provider says otherwise.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 23, 2012.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Beta-Sitosterol, straight from the product label.

Brand Vitabase
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD Mar 23, 2012
DSLD ID 5494
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult Male (18-50 Years), Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Beta-Sitosterol by Vitabase, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
IngredientAmount% DV
Beta-Sitosterol Complex500 mg--

Other ingredients: Gelatin, Magnesium Stearate, Microcrystalline Cellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to treat, cure, prevent or diagnose any disease.

Seals/Symbols

Vb

General Statements

Formulated to Support Prostate Health

Vitabase uses only high quality ingredients.

FDA Statement of Identity

DIETARY SUPPLEMENT

Precautions

ALLERGEN WARNING: CONTAINS SOY.

KEEP OUT OF REACH OF CHILDREN.

DO NOT USE IF OUTER SEAL IS DAMAGED OR MISSING.

CAUTION: Do not exceed recommended dose.

Pregnant or nursing mothers, children under 18 and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Suggested/Recommended/Usage/Directions

SUGGESTED USE: As a dietary supplement, take one (1) capsule daily or as directed by a health care professional.

Formulation

Contains No Sugar, No Starch, No Yeast, No Artificial Colors, Flavors or Preservatives.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Beta-Sitosterol by Vitabase label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Beta-Sitosterol label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Beta-Sitosterol by Vitabase

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Beta-Sitosterol Complex

No known
interactions
500 mg per serving

Beta-sitosterol is a plant sterol that may modestly lower LDL ('bad') cholesterol and may help ease urinary symptoms from an enlarged prostate. Eviden...

Beta-Sitosterol Complex monograph & interactions

Other (inactive) ingredients: Gelatin, Magnesium Stearate, Microcrystalline Cellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Beta-Sitosterol by Vitabase Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Beta-Sitosterol. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Beta-Sitosterol, from the product label.

Vitabase

See all Vitabase products
Name
Vitabase.com
City
Monroe
State
GA
ZipCode
30656
Pharmacist Counseling Corner

Beta-Sitosterol by Vitabase: Common Questions

Does Beta-Sitosterol by Vitabase interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Beta-Sitosterol. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Beta-Sitosterol contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What does beta-sitosterol actually do?
It's a plant sterol that helps your body manage cholesterol levels and may ease urinary symptoms from an enlarged prostate. Research shows it's likely effective for prostate issues and possibly effective for lowering cholesterol and heart disease risk.
Will this upset my stomach?
It can — constipation, diarrhea, gas, indigestion, and nausea are the most common side effects people report. Most are mild, but if you already have digestive issues, start low and see how you feel.
Can I take this if I'm pregnant or breastfeeding?
The safety data isn't there to say yes, so it's best to avoid it during pregnancy and breastfeeding. Talk with your doctor or pharmacist about whether it's right for you.
Will this make my acne worse?
Beta-sitosterol can worsen acne in some people. If you're prone to breakouts, mention this to your pharmacist or doctor before starting.
How long before I notice a difference?
The facts on file don't say how quickly you might see results, so talk with your doctor or pharmacist about what to expect based on the reason you're taking it.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Beta-Sitosterol is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Beta-Sitosterol label
Go deeper

The Full Monographs Behind Beta-Sitosterol’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Beta-sitosterol

Beta-sitosterol is a plant sterol that may modestly lower LDL ('bad') cholesterol and may help ease urinary symptoms from an enlarged prostate. Evidence is moderate for these uses and weaker...

Read the full Beta-sitosterol monograph →
Sources

Sources & How We Checked

Beta-Sitosterol's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 7 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Beta-sitosterol 7 references
  1. Berges RR, Windeler J, Trampisch HJ, et al. Randomised, placebo-controlled, double-blind clinical trial of beta-sitosterol in patients with benign prostatic hyperplasia. Beta-sitosterol Study Group. Lancet 1995;345:1529-32.
  2. Klippel KF, Hiltl DM, Schipp B. A multicentric, placebo-controlled, double-blind clinical trial of beta-sitosterol (phytosterol) for the treatment of benign prostatic hyperplasia. Br J Urol 1997;80:427-32.
  3. Wilt TJ, MacDonald R, Ishani A. beta-sitosterol for the treatment of benign prostatic hyperplasia: a systematic review. BJU Int 1999;83:976-83. PubMed
  4. Oster P, Schlierf G, Heuck CC, et al. [Sitosterol in familial hyperlipoproteinemia type II. A randomized, double-blind, cross-over study]. Dtsch Med Wochenschr 1976;101:1308-11.
  5. Becker M, Staab D, Von Bergman K. Long-term treatment of severe familial hypercholesterolemia in children: effect of sitosterol and bezafibrate. Pediatrics 1992;89:138-42. DOI
  6. Prager N, Bickett K, French N, Marcovici G. A randomized, double-blind, placebo-controlled trial to determine the effectiveness of botanically derived inhibitors of 5-alpha-reductase in the treatment of androgenetic alopecia. J Altern Complement Med 2002
  7. Lorenze A, Hsueh W, Nasr J. Beta-sitosterol-induced acute pancreatitis: A case report and review of the literature. Cureus. 2020;12(3):e7407. PubMed

See these in context on the Beta-sitosterol monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team