Interactions on record — worth a quick check against your medications. Based on 4 of 9 ingredients. Check your meds →
Dietary supplement

Women's Suprema Probiotic Ingredients & Drug Interactions

by Vitabase

Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Women's Suprema Probiotic is a dietary supplement by Vitabase with 9 active ingredients. Its ingredients are commonly taken for digestive and gut health, prebiotic to support good bacteria, constipation relief.Based on those ingredients, 302 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bifidobacterium breve Bb-03, Lactobacilli acidophilus La-14, FiberAid. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Women's Suprema Probiotic by Vitabase

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 9 active ingredients.
  • “Prebiotic Blend” is a proprietary blend — the label gives one combined amount (50 mg) without saying how much of each component you get.
  • “Proprietary Bifidobacterium Blend” is a proprietary blend — the label doesn't break down how much of each component you get.
  • “Proprietary Lactobacilli Blend” is a proprietary blend — the label doesn't break down how much of each component you get.

Women's Suprema Probiotic contains 9 active ingredients: live bacterial strains (probiotics) and a prebiotic blend to feed them. The probiotics include Lactobacillus acidophilus, Bifidobacterium breve, Bifidobacterium animalis lactis, and several others.

The prebiotic blend contains fructooligosaccharides and FiberAid (larch arabinogalactan) — these are carbohydrates that act as food for the beneficial bacteria. The capsule also holds inactive ingredients: cellulose, water, magnesium stearate, and calcium silicate.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: support urinary tract and vaginal health.
  • We looked for evidence on: Bacterial vaginosis, Urinary tract infections (UTIs), Vaginal candidiasis, Urogenital flora, Vaginal microbiome balance.
  • The strongest evidence on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Bacterial vaginosis (Natural Medicines).
  • Also on file: Lactobacillus Acidophilus is rated "Insufficient Reliable Evidence To Rate" for Urinary tract infections (UTIs), Vaginal candidiasis.

The evidence for this product's benefits is mixed and limited. Lactobacillus acidophilus is possibly effective for irritable bowel syndrome, antibiotic-associated diarrhea, and bacterial vaginosis, but the data aren't strong.

Bifidobacterium breve and the other strains have either insufficient evidence or show no real benefit for the conditions studied. Fructooligosaccharides and larch arabinogalactan have not been reliably studied for the health claims often made about probiotics and prebiotics — we hold insufficient evidence for most of their uses.

This doesn't mean they don't work; it means the science isn't settled yet.

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lactobacillus acidophilus is generally well tolerated in healthy adults and children. Bifidobacterium breve is also generally well tolerated but warrants caution in people who are very ill or immunocompromised — there have been rare cases of serious infection in critically ill patients and preterm infants.

Gastrointestinal side effects like bloating, flatulence, and abdominal pain can occur with probiotics and prebiotics, though they're usually mild and uncommon. Fructooligosaccharides and larch arabinogalactan may cause gas and bloating, especially at higher doses.

No pregnancy or breastfeeding safety data are on file for any of these ingredients, so talk with your doctor or pharmacist before use if you're pregnant or nursing.

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 4 matched ingredients can interact with medications — Lactobacillus Acidophilus, Larch Arabinogalactan, Bifidobacterium Breve.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs.
  • For scale: 302 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your medications before starting if you take antibiotic drugs or immunosuppressant drugs (used after transplants or for autoimmune diseases). Antibiotics could reduce this supplement's effectiveness, while immunosuppressants might be affected by the larch arabinogalactan in the prebiotic blend.

If you take either type, separate the timing with your pharmacist's help.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product is a multi-strain probiotic with prebiotic fiber aimed at digestive and immune support. It's generally well tolerated in healthy people, but if you take antibiotics, immunosuppressants, or have a weakened immune system, check with your pharmacist first.

Pregnant or nursing? Talk to your provider before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 9 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 22, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Women's Suprema Probiotic, straight from the product label.

Brand Vitabase
Net contents 30 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Aug 22, 2025
DSLD ID 329284
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult Female (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Women's Suprema Probiotic by Vitabase, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
30
IngredientAmount% DV
Bifidobacterium animalis lactis BL-040 NP--
Lactobacilli acidophilus La-140 NP--
Bifidobacterium breve Bb-030 NP--
Fructooligosaccharides0 NP--
Prebiotic Blend50 mg--
FiberAid0 NP--
Lactobacilli plantarum Lp-1150 NP--
Lactobacilli salivarius Ls-330 NP--
Proprietary Bifidobacterium Blend0 NP--
Proprietary Lactobacilli Blend0 NP--
Lactobacilli casei LC-110 NP--
Lactobacilli animalis lactis LL-230 NP--

Other ingredients: Cellulose, Water, Magnesium Stearate, Calcium Silicate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Our probiotic strains are stabilized using a patented poly matrix system (patent #6,653,062) that provides 50 billion microorganisms through expiration date when stored at room temperature.

Formula

Our probiotic strains are stabilized using a patented poly matrix system (patent #6,653,062) that provides 50 billion microorganisms through expiration date when stored at room temperature. Each Bio-Enhanced, Acid Resistant Strain (BEARS) has been specifically designed to survive stomach acid secretions during digestion eliminating the need for enteric coating. Our proprietary blend formula features the most dominant species of microorganisms (Lactobacilli) that nourish and support the vaginal and urinary organs. 50 billion viable cells

Formulation

Support urinary track & vaginal health Survives stomach acid

Storage

Shelf stable

FDA Statement of Identity

Dietary Supplement

Precautions

This product may contain trace amounts of dairy protein.

See for yourself

Women's Suprema Probiotic by Vitabase label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Women's Suprema Probiotic by Vitabase

These are the 9 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Prebiotic Blend

50 mg per serving

Proprietary Bifidobacterium Blend

0 NP per serving

Proprietary Lactobacilli Blend

0 NP per serving
  • Lactobacilli acidophilus La-14
  • › Lactobacilli plantarum Lp-115
  • › Lactobacilli salivarius Ls-33
  • › Lactobacilli casei LC-11
  • › Lactobacilli animalis lactis LL-23

Other (inactive) ingredients: Cellulose, Water, Magnesium Stearate, Calcium Silicate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Women's Suprema Probiotic by Vitabase Drug Interactions

Want to check YOUR meds against Women's Suprema Probiotic?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
302Drugs
302 Moderate

Ingredients driving the most interactions

FiberAid 121

Each ingredient & the kinds of drugs it affects

For each ingredient in Women's Suprema Probiotic with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Bifidobacterium breve Bb-031 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B. breve.
Since B. breve preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. breve preparations by at least 2 hours.

Likelihood Probable Evidence D

Lactobacilli acidophilus La-141 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.

Likelihood Probable Evidence D

FiberAid1 drug type · 121 drugs

Immunosuppressants

Theoretically, larch arabinogalactan might interfere with immunosuppression therapy due to immunostimulant effects. Immunosuppressant drugs include azathioprine (Imuran), basiliximab (Simulect), cyclosporine (Neoral, Sandimmune), daclizumab (Zenapax), muromonab-CD3 (OKT3, Orthoclone OKT3), mycophenolate (CellCept), tacrolimus (FK506, Prograf), sirolimus (Rapamune), prednisone (Deltasone, Orasone), corticosteroids (glucocorticoids), and other drugs.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Women's Suprema Probiotic, from the product label.

Vitabase

See all Vitabase products
Name
Vitabase
Pharmacist Counseling Corner

Women's Suprema Probiotic by Vitabase: Common Questions

Does Women's Suprema Probiotic by Vitabase interact with any medications?
Yes. Based on its ingredients, Women's Suprema Probiotic has a known interaction with 302 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Women's Suprema Probiotic contains 9 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this with antibiotics?
The live bacteria in this supplement could be killed by antibiotics, making both less effective. Talk to your pharmacist about spacing them out — usually you'll want to take them several hours apart.
What are probiotics and why are they in here?
Probiotics are live beneficial bacteria meant to support your gut health. This product contains multiple strains like Lactobacillus and Bifidobacterium, along with prebiotics (food for those bacteria) to help them survive and work.
Can I take this if I'm on an immunosuppressant?
The larch arabinogalactan in this supplement might interfere with immunosuppressant medications. Check with your doctor before using it, especially if you take drugs like cyclosporine or tacrolimus.
Will this cause side effects?
Bloating, gas, and mild abdominal discomfort can happen, especially when you first start — these are usually mild and often go away. In rare cases, serious infection has been reported in very ill or premature infants.
Is it safe in pregnancy or while breastfeeding?
We don't have safety data for any of these ingredients during pregnancy or breastfeeding. Talk with your doctor or pharmacist for personalized advice before using.
Does this actually work?
The evidence is limited. Lactobacillus acidophilus is possibly effective for a few conditions like irritable bowel syndrome and antibiotic-associated diarrhea, but for most uses the science isn't solid yet.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Women's Suprema Probiotic is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Women's Suprema Probiotic label
Sources

Sources & How We Checked

Women's Suprema Probiotic's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 38 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lactobacillus Acidophilus 15 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
  3. Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
  4. Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
  5. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  6. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
  7. Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
  10. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  11. Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
  12. Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
  13. Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
  14. Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
  15. Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.

See these in context on the Lactobacillus Acidophilus monograph →

Bifidobacterium Breve 9 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
  3. Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
  4. Ohishi A, Takahashi S, Ito Y, et al. Bifidobacterium septicemia associated with postoperative probiotic therapy in a neonate with omphalocele. J Pediatr. 2010;156(4):679-81. PubMed
  5. Sakurai Y, Watanabe T, Miura Y, et al. Clinical and bacteriologic characteristics of six cases of Bifidobacterium breve bacteremia due to probiotic administration in the neonatal intensive care unit. Pediatr Infect Dis J 2022;41(1):62-65. PubMed
  6. Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed
  7. Wakabayashi Y, Nakayama S, Yamamoto A, et al. First case of necrotizing fasciitis and bacteremia caused by Bifidobacteriumbreve. Anaerobe 2022;76:102613.
  8. Takeda Y, Ota K, Kondo A, et al. A case of necrotizing fasciitis caused by Bifidobacterium breve. IDCases 2022;31:e01667. PubMed
  9. Suwantarat N, Romagnoli M, Wakefield T, Carroll KC. Ventriculoperitoneal shunt infection caused by Bifidobacterium breve. Anaerobe 2014;28:1-3. PubMed

See these in context on the Bifidobacterium Breve monograph →

Fructo-oligosaccharides (fos) 6 references
  1. Briet F, et al. Symptomatic response to varying levels of fructo-oligosaccharides consumed occasionally or regularly. Eur J Clin Nutr 1995;49:501-7.
  2. Bouhnik Y, Vahedi K, Achour L, et al. Short-chain fructo-oligosaccharide administration dose-dependently increases fecal bifidobacteria in healthy humans. J Nutr 1999;129:113-6. PubMed
  3. Cummings JH, Macfarlane GT, Englyst HN. Prebiotic digestion and fermentation. Am J Clin Nutr 2001;73:415S-420S. PubMed
  4. Souza DDS, Tahan S, Weber TK, Araujo-Filho HB, de Morais MB. Randomized, double-blind, placebo-controlled parallel clinical trial assessing the effect of fructooligosaccharides in infants with constipation. Nutrients. 2018;10(11). pii: E1602. PubMed
  5. Andermann TM, Fouladi F, Tamburini FB, et al. A Fructo-Oligosaccharide Prebiotic Is Well Tolerated in Adults Undergoing Allogeneic Hematopoietic Stem Cell Transplantation: A Phase I Dose-Escalation Trial. Transplant Cell Ther 2021;27(11):932. PubMed
  6. Dou Y, Yu X, Luo Y, Chen B, Ma D, Zhu J. Effect of Fructooligosaccharides Supplementation on the Gut Microbiota in Human: A Systematic Review and Meta-Analysis. Nutrients 2022;14(16):3298. PubMed

See these in context on the Fructo-oligosaccharides (fos) monograph →

Larch Arabinogalactan 8 references
  1. D'Adamo P. Larch arabinogalactan. J Naturopath Med 1996;6:33-7.
  2. Kelly GS. Larch arabinogalactan: Clinical relevance of a novel immune-enhancing polysaccharide. Alt Med Rev 1999;4:96-103.
  3. Marett R, Slavin JL. No long-term benefits of supplementation with arabinogalactan on serum lipids and glucose. J Am Diet Assoc 2004;104:636-9.
  4. Robinson RR, Feirtag J, Slavin JL. Effects of dietary arabinogalactan on gastrointestinal and blood parameters in healthy human subjects. J Am Coll Nutr 2001;20:279-85. PubMed
  5. Udani JK, Singh BB, Barrett ML, Singh VJ. Proprietary arabinogalactan extract increases antibody response to the pneumonia vaccine: a randomized, double-blind, placebo-controlled, pilot study in healthy volunteers. Nutr J 2010;9:32. PubMed
  6. Grube B, Stier H, Riede L, Gruenwald J. Tolerability of a proprietary larch arabinogalactan extract: a randomized, double-blind, placebo-controlled clinical trial in healthy subjects. Food Nutr Sci 2012;3:1533-8. DOI
  7. Dion C, Chappuis E, Ripoll C. Does larch arabinogalactan enhance immune function? A review of mechanistic and clinical trials. Nutr Metab (Lond) 2016;13:28. PubMed
  8. Riede L, Grube B, Gruenwald J. Larch arabinogalactan effects on reducing incidence of upper respiratory tract infections. Curr Med Res Opin 2013;29(3):251-8.

See these in context on the Larch Arabinogalactan monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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