Interactions on record — worth a quick check against your medications. Based on 5 of 6 ingredients. Check your meds →
Dietary supplement

Bilberry Supreme Ingredients & Drug Interactions

by Maxi Health

Bilberry Supreme label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Bilberry Supreme against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Bilberry Supreme is a dietary supplement by Maxi Health with 6 active ingredients. Its ingredients are commonly taken for vitamin c source, digestive support, flavoring and aromatherapy.Based on those ingredients, 276 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bilberry extract, Zeaxanthin, Eyebright, Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Bilberry Supreme by Maxi Health

Ask about any prescription or over-the-counter medication and we check it for interactions with Bilberry Supreme by Maxi Health — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Bilberry Supreme by Maxi Health

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Oct 1, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 6 of its 6 active ingredients.
  • “Lemon Bioflavonoid Complex” is a proprietary blend — the label gives one combined amount (100 mg) without saying how much of each component you get.
  • “Bilberry extract” is listed as a grouped ingredient — the label gives one combined amount (50 mg) without saying how much of each component you get.

Bilberry Supreme contains 6 active ingredients chosen for eye health. Lutein and zeaxanthin are carotenoids (plant pigments) that deposit in the retina and are the main compounds studied for vision support.

Eyebright powder, lemon bioflavonoid complex, bilberry extract, and anthocyanidins contribute additional antioxidant compounds. The product also includes inactive ingredients — cellulose, microcrystalline cellulose, magnesium stearate, and Enzymax — which serve as capsule materials and flow agents.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: eye and vision health.
  • We looked for evidence on: Age-related macular degeneration (AMD), Asthenopia (eye strain), Cataracts, Conjunctivitis, Dry eye, Myopia — and 4 related terms.
  • The strongest evidence on file: Lutein is rated "Possibly Effective" for Age-related macular degeneration (AMD) (Natural Medicines).
  • Also on file: Lutein is rated "Possibly Effective" for Cataracts.
  • Also on file: Zeaxanthin is rated "Possibly Effective" for Age-related macular degeneration (AMD).

The evidence varies by ingredient and condition. Lutein and zeaxanthin both carry a "Possibly Effective" rating for age-related macular degeneration (AMD) — the most common reason people use products like this.

Lutein also rates "Possibly Effective" for cataracts. For the other conditions listed in our data — retinitis pigmentosa, retinopathy of prematurity, bronchopulmonary dysplasia, and age-related cognitive decline — the evidence is insufficient to rate them, or the ingredient is rated ineffective.

Eyebright shows insufficient evidence for allergic rhinitis, cancer, cold, cough, sore throat, and sinus infection. We could not establish effectiveness ratings for anthocyanidins, total bioflavonoids, lemon bioflavonoid complex, bilberry extract, or PureWay-C from the data we hold.

The evidence, ingredient by ingredient Lemon Bilberry Lutein Zeaxanthin Eyebright

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lutein and zeaxanthin are generally well tolerated at typical supplement doses. Lutein at up to 20 mg daily has not caused adverse effects in trials.

Eyebright, however, has been reported to cause confusion, headache, nausea, constipation, cough, shortness of breath, and nasal congestion when taken by mouth. Regarding pregnancy and breastfeeding, lutein and zeaxanthin are both rated "Likely Safe," though the facts note there is not enough data on concentrated supplement doses during pregnancy and breastfeeding — talk with your doctor or pharmacist for personalized advice.

Eyebright should be avoided during pregnancy and breastfeeding because safety has not been established.

Side effects, ingredient by ingredient Lemon Bilberry Lutein Zeaxanthin Eyebright

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 3 matched ingredients can interact with medications — Eyebright, Zeaxanthin.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you take antidiabetes drugs (including insulin and other glucose-lowering medications). Zeaxanthin and eyebright may theoretically increase the risk of low blood sugar.

No other medication types show documented interactions with the ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Bilberry Supreme is aimed at supporting eye health, particularly for age-related macular degeneration, and its two main ingredients carry modest supporting evidence. If you take antidiabetes medications, you'll need to check with your doctor or pharmacist before starting, because zeaxanthin and eyebright may lower blood sugar.

Eyebright also carries a caution about potential side effects like nausea and headache. Overall, run your current medications through the interaction checker on this page and discuss the product with your own healthcare provider.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Bilberry Supreme, straight from the product label.

Brand Maxi Health
Barcode (UPC) 753406088065
Net contents 60 Maxicap(s)
Market status On market
Date entered into DSLD Jul 25, 2024
DSLD ID 304157
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Bilberry Supreme by Maxi Health, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Maxicap(s)
Maximum serving Sizes:
1 Maxicap(s)
Servings per container
40
UPC/BARCODE
753406088065
IngredientAmount% DV
Lemon Bioflavonoid Complex100 mg--
Anthocyanidins12.5 mg--
Bilberry extract50 mg--
Total Bioflavonoids50 mg--
Lutein5 mg--
Zeaxanthin300 mcg--
PureWay-C300 mg500%
Eyebright, Powder50 mg--

Other ingredients: Cellulose, Microcrystalline Cellulose, Magnesium Stearate, Enzymax

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: Take one (1) Maxicap twice daily, or as directed.

Precautions

If pregnant or nursing, consult your healthcare practitioner before using any dietary supplement.

Keep out of reach of children.

Storage

Keep tightly closed in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formulation

Vegetarian

Vision Support

This product was manufactured in a GMP Certified facility.

This product contains no animal products, wheat, gluten, sugar, salt, yeast, milk, artificial flavors, colorings or preservatives.

Formula

Certified Kosher

Eye Support Formula with Lutein PureWay-C

OU (Kosher)

Enzymax

General Statements

Doctor formulated

See goodness in the world

Seals/Symbols

UK (Rav Shmuel Dovid Krausz (Udvarer Rav)) (Kosher) BDZ Edah Charedis - Orthodox Council of Jerusalem (Kosher) OU (Kosher)

Manufactured in a certified GMP facility

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

MaxiHealth True to total wellness

FloraGLO is a registered trademark of Kemin Foods, LC. Enzymax, a vital digestive enzyme complex, is a registered trademark of Maxi Health Research LLC. PureWay-C is a registered trademark of Innovation Laboratories, Inc.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Bilberry Supreme by Maxi Health label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Bilberry Supreme label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Bilberry Supreme by Maxi Health

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Maxicap(s) Dosage formCapsule Servings per container40 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Lemon Bioflavonoid Complex

Interacts with
1 drug
100 mg per serving

Lemon is a common citrus fruit that is a good source of vitamin C and citric acid, and it is widely used in food, drinks, and home remedies. While it...

Lemon Bioflavonoid Complex monograph & interactions
  • › Total Bioflavonoids

Bilberry extract

Interacts with
275 drugs
50 mg per serving

Bilberry is a blueberry-like fruit rich in antioxidant plant compounds called anthocyanins, and it has a long history of traditional use for eye healt...

Bilberry extract monograph & interactions
  • › Anthocyanidins

Lutein

No known
interactions
5 mg per serving Form: FloraGLO Lutein

Lutein is a plant-based antioxidant pigment that concentrates in the eye, and the best evidence suggests it (often combined with zeaxanthin) may help...

Lutein monograph & interactions

Zeaxanthin

Interacts with
86 drugs
300 mcg per serving Form: FloraGLO Lutein

Zeaxanthin is a carotenoid pigment that, along with lutein, concentrates in the macula of the eye and may help support long-term eye health. The stron...

Zeaxanthin monograph & interactions

PureWay-C

300 mg per serving Form: Ascorbic Acid, Lipid Metabolites, Vegetable Waxes

Eyebright, Powder

Interacts with
86 drugs
50 mg per serving Form: Euphrasia officinalis, Powder

Eyebright is a traditional herb long used for minor eye irritation, redness, and allergy symptoms, but high-quality human studies are very limited. Th...

Eyebright, Powder monograph & interactions

Other (inactive) ingredients: Cellulose, Microcrystalline Cellulose, Magnesium Stearate, Enzymax. These complete the product’s ingredient list but are not active constituents.

Interaction report

Bilberry Supreme by Maxi Health Drug Interactions

Want to check YOUR meds against Bilberry Supreme?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
276Drugs
275 Moderate 1 Minor

Ingredients driving the most interactions

Bilberry extract 275
Zeaxanthin 86
Eyebright, Powder 86
Lemon Bioflavonoid Complex 1

Individual Drug Interactions

The ingredients in Bilberry Supreme interact with 276 drugs. Click any drug to see the details.

4 of the 6 ingredients in Bilberry Supreme interact with drugs. Each result below shows which ingredient is responsible. Bilberry extract Zeaxanthin Eyebright, Powder Lemon Bioflavonoid Complex

Each ingredient & the kinds of drugs it affects

For each ingredient in Bilberry Supreme with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Bilberry extract4 drug types · 275 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, bilberry fruit extract might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro, animal, and clinical research suggest that anthocyanidin extracts from bilberry can inhibit platelet aggregation.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, bilberry leaf or fruit extract may increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research suggests that bilberry leaf extract might have blood glucose-lowering activity. Also, one small clinical trial in patients with type 2 diabetes shows that taking bilberry fruit extract 470 mg as a single dose prior to an oral glucose tolerance test lowers plasma glucose levels when compared with placebo.

Likelihood Possible Evidence D
Cytochrome P450 2E1 (Cyp2E1) Substrates

Theoretically, bilberry fruit extract might decrease levels of drugs metabolized by CYP2E1.
Animal research shows that exposure to small concentrations of bilberry extract in drinking water for around one month increased CYP2E1 activity by 31%. However, exposure over a 2-month period did not increase CYP2E1 activity. This effect has not been reported in humans.

Likelihood Possible Evidence D
Erlotinib (Tarceva)

Theoretically, bilberry fruit extract might reduce the efficacy of erlotinib.
In vitro research suggests that bilberry fruit extract and its constituents, delphinidin and delphinidin-3-O-glucoside, inhibit the activity of erlotinib. This interaction has not been reported in humans.

Likelihood Possible Evidence D
Bilberry extract full monograph & interactions

Zeaxanthin1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking zeaxanthin with antidiabetes drugs might increase the risk of hypoglycemia.
In an animal diabetic model, zeaxanthin has hypoglycemic effects. However, population research has found that increasing intake of dietary zeaxanthin plus lutein does not decrease the risk of developing type 2 diabetes.

Likelihood Possible Evidence D
Zeaxanthin full monograph & interactions

Eyebright, Powder1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, eyebright might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research suggests that eyebright lowers blood glucose levels.

Likelihood Possible Evidence D
Eyebright, Powder full monograph & interactions

Lemon Bioflavonoid Complex1 drug type · 1 drug

Itraconazole (Sporanox)

Theoretically, taking itraconazole capsules or tablets with a beverage containing lemon might increase the levels and clinical effects of itraconazole.
In one case report, dissolving itraconazole tablets in a small amount of specific beverages containing lemon prior to administration increased the level of itraconazole in a lung transplant patient. In this case, the increased bioavailability was desirable and was likely due to improved tablet dissolution in the acidic beverage.

Likelihood Possible Evidence D
Lemon Bioflavonoid Complex full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Bilberry Supreme, from the product label.

Maxi Health

See all Maxi Health products
Name
Maxi Health
City
Brooklyn
State
N.Y.
Phone Number
800-544-6294
Web Address
www.maxihealth.com
Pharmacist Counseling Corner

Bilberry Supreme by Maxi Health: Common Questions

Does Bilberry Supreme by Maxi Health interact with any medications?
Yes. Based on its ingredients, Bilberry Supreme has a known interaction with 276 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Bilberry Supreme contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while I'm pregnant or breastfeeding?
Lutein and zeaxanthin are both rated "Likely Safe" in pregnancy and lactation, but there isn't enough data on concentrated supplement doses — the safety facts recommend caution. Eyebright, however, should be avoided during pregnancy and breastfeeding because safety has not been established. Talk with your doctor or pharmacist about whether this product is right for you.
What does lutein actually do?
Lutein is a carotenoid — a natural plant pigment — that deposits in your retina. It's been studied most for age-related macular degeneration and cataracts, where it rates "Possibly Effective" in our data. You get some lutein from leafy greens and eggs, and this supplement provides a concentrated dose.
Are there any side effects I should know about?
Lutein and zeaxanthin are generally well tolerated. Eyebright, however, has been reported to cause confusion, headache, nausea, constipation, cough, shortness of breath, and nasal congestion when taken by mouth. If you notice any of these, stop and talk with your pharmacist.
Does this product have fillers?
Yes, it includes inactive ingredients: cellulose, microcrystalline cellulose, magnesium stearate, and Enzymax, which are standard capsule materials and flow agents.
Will this work for dry eyes or eye strain?
The evidence we hold shows lutein and zeaxanthin are "Possibly Effective" for age-related macular degeneration and cataracts. We don't have effectiveness data for dry eyes or eye strain in our monographs, so talk with your eye doctor about whether this product fits your specific needs.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Bilberry Supreme is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Bilberry Supreme label
Go deeper

The Full Monographs Behind Bilberry Supreme’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lemon

Interacts with 1 drug

Lemon is a common citrus fruit that is a good source of vitamin C and citric acid, and it is widely used in food, drinks, and home remedies. While it can support hydration and a healthy diet...

Read the full Lemon monograph → Herb & supplement monograph

Bilberry

Interacts with 275 drugs

Bilberry is a blueberry-like fruit rich in antioxidant plant compounds called anthocyanins, and it has a long history of traditional use for eye health, circulation, and mild diarrhea. While...

Read the full Bilberry monograph → Herb & supplement monograph

Lutein

Lutein is a plant-based antioxidant pigment that concentrates in the eye, and the best evidence suggests it (often combined with zeaxanthin) may help slow progression of age-related macular...

Read the full Lutein monograph → Herb & supplement monograph

Zeaxanthin

Interacts with 86 drugs

Zeaxanthin is a carotenoid pigment that, along with lutein, concentrates in the macula of the eye and may help support long-term eye health. The strongest evidence relates to slowing progres...

Read the full Zeaxanthin monograph → Herb & supplement monograph

Eyebright

Interacts with 86 drugs

Eyebright is a traditional herb long used for minor eye irritation, redness, and allergy symptoms, but high-quality human studies are very limited. There is not enough reliable evidence to c...

Read the full Eyebright monograph →
Sources

Sources & How We Checked

Bilberry Supreme's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 26 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lemon 2 references
  1. Ruggenenti P, Caruso MR, Cortinovis M, et al. Fresh lemon juice supplementation for the prevention of recurrent stones in calcium oxalate nephrolithiasis: A pragmatic, prospective, randomised, open, blinded endpoint (PROBE) trial. EClinicalMedicine 2021;4 PubMed
  2. Umemura K, Katada Y, Nakagawa S, et al. Improved absorption of itraconazole tablet by co-administration with lemon beverages in a lung transplant recipient: A case report. J Infect Chemother 2022;28(8):1203-1207. PubMed

See these in context on the Lemon monograph →

Bilberry 14 references
  1. Cignarella A, Nastasi M, Cavalli E, Puglisi L. Novel lipid-lowering properties of Vaccinium myrtillus L. leaves, a traditional antidiabetic treatment, in several models of rat dyslipidaemia: a comparison with ciprofibrate. Thromb Res 1996;84:311-22. PubMed
  2. Morazzoni P, Magistretti MJ. Activity of Myrtocyan, an anthosyanoside complex from Vaccinium myrtillus (VMA), on platelet aggregation and adhesiveness. Fitoterapia 1990;61:13-21.
  3. Erlund, I., Koli, R., Alfthan, G., Marniemi, J., Puukka, P., Mustonen, P., Mattila, P., and Jula, A. Favorable effects of berry consumption on platelet function, blood pressure, and HDL cholesterol. Am J Clin Nutr 2008;87(2):323-331. PubMed
  4. Hawrelak, J. A. and Myers, S. P. Effects of two natural medicine formulations on irritable bowel syndrome symptoms: a pilot study. J Altern Complement Med 2010;16(10):1065-1071. PubMed
  5. Morazzoni P and Magistretti MJ. Effects of Vaccinium myrtillus anthocyanosides on prostacyclin-like activity in rat arterial issue. Fitoterapia 1986;57:11-14.
  6. Pulliero G, Montin S, Bettini V, and et al. Ex vivo study of the inhibitory effects of Vaccinium myrtillus anthocyanosides on human platelet aggregation. Fitoterapia 1989;60:69-75.
  7. Bottecchia D. Preliminary report on the inhibitory effect of vaccinium myrtillus anthocyanosides on platelet aggregation and clot retraction. Fitoterapia 1987;48:3-8.
  8. Fdez, M., Zaragoza, F., and Alvarez, P. In vitro platelet aggregation effects of anthocyanosides of vaccinium myrtilus L. Anales de la Real Academia de Farmacia 1983;49:79-90.
  9. Biedermann L, Mwinyi J, Scharl M, Frei P, Zeitz J, Kullak-Ublick GA, et al. Bilberry ingestion improves disease activity in mild to moderate ulcerative colitis-an open pilot study. 2013 May;7(4):271-9. PubMed
  10. Hoggard N, Cruickshank M, Moar KM, Bestwick C, Holst J, Russell W, et al. A single supplement of a standardized bilberry (Vaccinium myrtillus L.) extract (36% wet weight anthocyanins) modifies glycaemic response in individuals with type 2 diabetes control
  11. Aichinger G, Pahlke G, Nagel LJ, Berger W, Marko D. Bilberry extract, its major phenolic compounds, and soy isoflavone genistein antagonize the cytostatic drug erlotinib in human epithelial cells. Food Funct 2016;7(8):3628-36.
  12. Prokop J, Lněničková K, Cibicek N, et al. Effect of bilberry extract (Vaccinium myrtillus L.) on drug-metabolizing enzymes in rats. Food Chem Toxicol 2019;129:382-90. PubMed
  13. Chan SW, Chu TTW, Choi SW, Benzie IFF, Tomlinson B. Impact of short-term bilberry supplementation on glycemic control, cardiovascular disease risk factors, and antioxidant status in Chinese patients with type 2 diabetes. Phytother Res 2021. Online ahead o PubMed
  14. Bøhn SK, Myhrstad MCW, Thoresen M, et al. Bilberry/red grape juice decreases plasma biomarkers of inflammation and tissue damage in aged men with subjective memory impairment -a randomized clinical trial. BMC Nutr 2021;7(1):75. PubMed

See these in context on the Bilberry monograph →

Lutein 2 references
  1. Brown L, Rimm EB, Seddon JM, et al. A prospective study of carotenoid intake and risk of cataract extraction in US men. Am J Clin Nutr 1999;70:517-24. PubMed
  2. Chasan-Taber L, Willett WC, Seddon JM, et al. A prospective study of carotenoid and vitamin A intakes and risk of cataract extraction in US women. Am J Clin Nutr 1999;70:509-16. PubMed

See these in context on the Lutein monograph →

Zeaxanthin 4 references
  1. Montonen J, Knekt P, Jarvinen R, Reunanen A. Dietary antioxidant intake and risk of type 2 diabetes. Diabetes Care 2004;27:362-6. PubMed
  2. Leermakers ET, Darweesh SK, Baena CP, et al. The effects of lutein on cardiometabolic health across the life course: a systematic review and meta-analysis. Am J Clin Nutr 2016;103(2):481-94. PubMed
  3. Kou L, Du M, Zhang C, Dai Z, Li X, Zhang B. The Hypoglycemic, Hypolipidemic, and Anti-Diabetic Nephritic Activities of Zeaxanthin in Diet-Streptozotocin-Induced Diabetic Sprague Dawley Rats. Appl Biochem Biotechnol 2017;182(3):944-955. PubMed
  4. Xu X, Zhao X, Berde Y, Low YL, Kuchan MJ. Milk and Plasma Lutein and Zeaxanthin Concentrations in Chinese Breast-Feeding Mother-Infant Dyads With Healthy Maternal Fruit and Vegetable Intake. J Am Coll Nutr 2019;38(2):179-184. PubMed

See these in context on the Zeaxanthin monograph →

Eyebright 4 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Wichtl MW. Herbal Drugs and Phytopharmaceuticals. Ed. N.M. Bisset. Stuttgart: Medpharm GmbH Scientific Publishers, 1994.
  3. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  4. Porchezhian, E., Ansari, S. H., and Shreedharan, N. K. Antihyperglycemic activity of Euphrasia officinale leaves. Fitoterapia 2000;71(5):522-526. PubMed

See these in context on the Eyebright monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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