No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 3 of 10 ingredients. Check your meds →
Dietary supplement

BioCore Optimum Complete Ingredients & Drug Interactions

by Swanson

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

BioCore Optimum Complete is a dietary supplement by Swanson with 10 active ingredients. Its ingredients are commonly taken for digestive support, bloating and gas, fat digestion.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of BioCore Optimum Complete by Swanson

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 10 active ingredients.
  • “BioCore Optimum Complete” is listed as a grouped ingredient — the label gives one combined amount (220 mg) without saying how much of each component you get.

BioCore Optimum Complete contains 10 active digestive enzymes. Lipase helps break down fats, lactase breaks down the milk sugar lactose, and protease breaks down proteins.

The product also includes amylase (for carbohydrates), alpha-galactosidase, glucoamylase, invertase, acid maltase, and peptidase—all designed to support different stages of digestion. The inactive ingredients are rice bran, hypromellose, dextrin, maltodextrin, and medium chain triglyceride.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: assists breaking down foods more efficiently.
  • We looked for evidence on: Lactose intolerance, Dyspepsia, indigestion, malabsorption.
  • The strongest evidence on file: Lactase is rated "Effective" for Lactose intolerance (Natural Medicines).
  • Also on file: Lipase is rated "Insufficient Reliable Evidence To Rate" for Dyspepsia.

Lactase in this product is rated effective for lactose intolerance—the evidence supports its use if you have trouble digesting dairy. For the other enzymes—lipase, protease, and the rest—the evidence isn't established in the data we hold.

Lipase and protease show insufficient reliable evidence for inflammatory bowel disease, dyspepsia, and other conditions we track; the remaining ingredients have no effectiveness ratings on file. That doesn't mean they don't work, just that the clinical evidence we have access to doesn't support specific claims yet.

The evidence, ingredient by ingredient Lipase Lactase Proteolytic Enzymes (proteases)

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lipase and lactase are generally well tolerated. Protease may cause digestive upset or allergic reactions in some people and should be avoided in pregnancy unless prescribed by your doctor; breastfeeding safety hasn't been well studied, so check with your healthcare provider first.

Lipase has little safety data in pregnancy—use only if your doctor advises it—and breastfeeding safety hasn't been well studied either. Lactase is likely safe in pregnancy but warrants a quick check with your doctor before regular use; limited data exists for breastfeeding, but since it acts only in the gut, ask your pharmacist or doctor first.

One case of allergic reaction (contact dermatitis and allergic rhinitis) to lactase has been reported in a worker exposed to powdered lactase powder.

Side effects, ingredient by ingredient Lipase Lactase Proteolytic Enzymes (proteases)

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 3 matched ingredients has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. We were unable to verify amylase, alpha-galactosidase, glucoamylase, invertase, acid maltase, and peptidase for drug interactions, so check your specific medications using the tool on this page, and mention this product to your pharmacist or doctor if you take any prescriptions regularly.

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

This enzyme blend works best if you need lactase for lactose intolerance; for the other enzymes, the evidence isn't clear yet. If you're pregnant or breastfeeding, or if you have a serious digestive condition, talk with your doctor or pharmacist about whether it's right for you before starting.

Because we couldn't check all the ingredients for drug interactions, search your medications on this page to be sure.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 10 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 16, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about BioCore Optimum Complete, straight from the product label.

Brand Swanson
Barcode (UPC) 087614024455
Net contents 90 Veggie Cap(s)
Market status On market
Date entered into DSLD Jun 16, 2022
DSLD ID 265057
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for BioCore Optimum Complete by Swanson, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Veggie Capsule(s)
Maximum serving Sizes:
1 Veggie Capsule(s)
Servings per container
90
UPC/BARCODE
087614024455
IngredientAmount% DV
Lipase0 NP--
Lactase0 NP--
BioCore Optimum Complete220 mg--
Amylase0 NP--
Protease0 NP--
Alpha-Galactosidase0 NP--
Glucoamylase0 NP--
Protease0 NP--
Invertase0 NP--
Acid Maltase0 NP--
Peptidase0 NP--

Other ingredients: Rice Bran, Hypromellose, Dextrin, Maltodextrin, Medium Chain Triglyceride

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

swanson.com or call 1-800-437-4148

Science-Backed Quality Since 1969

Formulation

Digestive enzyme derived from plant sources Assists in breaking down foods more efficiently

Digestive Health Comprehensive Enzyme Formula

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take one veggie capsule with water immediately before each meal.

Brand IP Statement(s)

BioCore Optimum Complete is a registered trademark of Deerland Probiotics & Enzymes, Inc.

Precautions

Warning: For adults only.

Consult your healthcare provider before using this or any product if you are pregnant or nursing, taking medication or have a medical condition.

Keep out of reach of children.

Do not use if seal is broken.

May contain tree nut (coconut).

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Dietary Supplement

See for yourself

BioCore Optimum Complete by Swanson label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in BioCore Optimum Complete by Swanson

These are the 10 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Veggie Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

BioCore Optimum Complete

220 mg per serving
  • › Lipase
  • › Lactase
  • › Amylase
  • › Protease
  • › Alpha-Galactosidase
  • › Glucoamylase
  • › Protease
  • › Invertase
  • › Acid Maltase
  • › Peptidase

Other (inactive) ingredients: Rice Bran, Hypromellose, Dextrin, Maltodextrin, Medium Chain Triglyceride. These complete the product’s ingredient list but are not active constituents.

Interaction report

BioCore Optimum Complete by Swanson Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in BioCore Optimum Complete. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for BioCore Optimum Complete, from the product label.

Swanson

See all Swanson products
Name
Swanson Health Products
City
Fargo
State
ND
ZipCode
58104
Phone Number
1-800-437-4148
Web Address
swanson.com
Pharmacist Counseling Corner

BioCore Optimum Complete by Swanson: Common Questions

Does BioCore Optimum Complete by Swanson interact with any medications?
We do not currently list a known interaction for the mapped ingredients in BioCore Optimum Complete. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
BioCore Optimum Complete contains 10 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does lactase in this product actually work for lactose intolerance?
Yes—lactase is rated effective for lactose intolerance. It breaks down the milk sugar your body has trouble digesting, so it can help if dairy upsets your stomach.
Is it safe to take this while pregnant?
The safety data varies by ingredient. Lactase is likely safe in pregnancy, but check with your doctor before regular use. Lipase has little safety data in pregnancy—use only if your doctor advises it. Protease should be avoided in pregnancy unless prescribed. Talk with your doctor before starting.
Can I take this while breastfeeding?
Lactase acts only in the gut and is likely safe, but ask your doctor or pharmacist first. Lipase and protease have limited breastfeeding safety data, so check with your healthcare provider before using either regularly.
What are the side effects I should watch for?
No adverse effects have been widely reported in adults. Protease may cause digestive upset or allergic reactions in some people. One case of allergic reaction (contact dermatitis and allergic nose/eye symptoms) to lactase has been reported in a worker exposed to powdered lactase.
Is this safe if I have a digestive condition like IBS or Crohn's disease?
Lipase and the other enzymes in this product should be used only under medical guidance if you have a serious digestive condition. Talk with your doctor before starting.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if BioCore Optimum Complete is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

BioCore Optimum Complete label
Sources

Sources & How We Checked

BioCore Optimum Complete's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lipase 1 reference
  1. Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed

See these in context on the Lipase monograph →

Lactase 1 reference
  1. Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed

See these in context on the Lactase monograph →

Proteolytic Enzymes (proteases) 3 references
  1. Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
  2. Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
  3. Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed

See these in context on the Proteolytic Enzymes (proteases) monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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