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Dietary supplement

Biotin Ingredients & Drug Interactions

by Global Healing Center

Capsule Category: Other Combinations
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Biotin is a dietary supplement by Global Healing Center with 2 active ingredients. Its ingredients are commonly taken for general wellness and energy, gut health, antioxidant support.Based on those ingredients, 257 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Fulvic Acid. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Biotin by Global Healing Center

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product has 2 active ingredients: fulvic acid and biotin. Fulvic acid is an organic compound derived from soil and plant matter; biotin is a B vitamin your body needs for healthy hair, skin, and nails, and it plays a role in metabolism.

The capsule itself is vegetarian, and the formulation includes organic gum acacia as a binder.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: support healthy skin, hair, and nails.
  • We looked for evidence on: Alopecia areata, Atopic dermatitis (eczema), Biotin deficiency, Brittle nails, Seborrheic dermatitis, hair loss — and 3 related terms.
  • The strongest evidence on file: Biotin is rated "Likely Effective" for Biotin deficiency (Natural Medicines).
  • Also on file: Biotin is rated "Possibly Ineffective" for Seborrheic dermatitis.
  • Also on file: Biotin is rated "Insufficient Reliable Evidence To Rate" for Alopecia areata, Brittle nails.

Biotin is likely effective for treating biotin deficiency, which is rare but can happen with certain medications or malabsorption issues. For other conditions listed—alopecia areata, multiple sclerosis, and seborrheic dermatitis—the evidence we hold rates biotin as possibly ineffective or shows insufficient data to make a reliable claim.

For fulvic acid, the evidence we hold is insufficient to establish it works for respiratory infections, lead toxicity, eczema, fatigue, or hay fever.

The evidence, ingredient by ingredient Fulvic Acid Biotin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 1 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Biotin is generally well tolerated, even at higher doses, because your body excretes excess amounts in urine. High-dose biotin has rarely caused mild diarrhea, and one unconfirmed case involved an unusual inflammatory reaction, though it's unclear if biotin was the cause.

Fulvic acid appears well tolerated in the short term, but high-quality human safety data is limited. Common side effects from oral fulvic acid include diarrhea, headache, and sore throat; a rare serious effect called Kashin-Beck bone disease has been noted.

Fulvic acid is not advised during pregnancy or breastfeeding due to insufficient safety information. For biotin, normal dietary and supplement amounts are appropriate during pregnancy and lactation, but discuss high-dose supplements with your doctor first.

Side effects, ingredient by ingredient Fulvic Acid Biotin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Fulvic Acid.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs.
  • For scale: 257 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you take blood thinners or antiplatelet drugs (like warfarin or aspirin), immune-suppressing medications, or thyroid hormone replacement. Fulvic acid may reduce how well these work.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product may appeal to people with biotin deficiency or those seeking general hair and skin support, but the fulvic acid component carries meaningful interactions with blood thinners, immune suppressants, and thyroid medications. If you take any of those drug types, or if you're pregnant or breastfeeding, talk with your doctor or pharmacist before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 24, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Biotin, straight from the product label.

Brand Global Healing Center
Barcode (UPC) 769173635883
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Jul 24, 2019
DSLD ID 204477
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Biotin by Global Healing Center, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
769173635883
IngredientAmount% DV
Fulvic Acid10 mg--
Biotin2500 mcg8333%

Other ingredients: Vegetarian Capsule, organic Gum Acacia

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use Take one capsule daily, preferably with food, or as recommended by your healthcare practitioner.

Formula

Our biotin is extracted from certified organic sesbania herb along with the natural co-factors and co-nutrients in the plant. It is an essential vitamin that helps support healthy skin, hair, and nails.

Biotin from natural Sesbania extract

Formulation

Our biotin is extracted from certified organic sesbania herb along with the natural co-factors and co-nutrients in the plant.

GMO Free

Vegan

Gluten Free

Precautions

Warning: Keep out of reach of children.

Consult your healthcare provider if pregnant, nursing or for any additional concerns.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General Statements

Since 1998

FDA Statement of Identity

All Natural Dietary Supplement

Seals/Symbols

GMO Free

Vegan

Gluten Free

No Animal Testing

Brand IP Statement(s)

Oregen-Bio is a registered trademark of Orgenetic, Incorporated.

See for yourself

Biotin by Global Healing Center label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Biotin by Global Healing Center

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Fulvic Acid

Interacts with
257 drugs
10 mg per serving

Fulvic acid is a natural compound formed when plants and microbes break down in soil, and it is sold as a supplement for energy, gut, and overall well...

Fulvic Acid monograph & interactions

Biotin

No known
interactions
2500 mcg per serving Form: organic Sesbania extract

Biotin (vitamin B7) is a water-soluble vitamin your body needs to turn food into energy and to support healthy hair, skin, and nails. Most people get...

Biotin monograph & interactions

Other (inactive) ingredients: Vegetarian Capsule, Organic Gum Acacia. These complete the product’s ingredient list but are not active constituents.

Interaction report

Biotin by Global Healing Center Drug Interactions

Want to check YOUR meds against Biotin?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
257Drugs
257 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Biotin with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Fulvic Acid3 drug types · 257 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, taking fulvic acid may decrease the effectiveness of anticoagulant and antiplatelet drugs.
In vitro evidence shows that fulvic acid, formed from the oxidation and polymerization of protocatechuic acid, can shorten prothrombin time in human plasma, increasing the risk of clot formation.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, taking fulvic acid might decrease the effects of immunosuppressive therapy.
Animal research shows that fulvic acid stimulates immune function.

Likelihood Possible Evidence D
Thyroid Hormone

Theoretically, taking fulvic acid with thyroid hormone therapy might interfere with the ability to normalize thyroid function.
Animal research shows that fulvic acid increases the plasma level of thyroid-stimulating hormone (TSH) and decreases the thyroxine (T4):triiodothyronine (T3) ratio.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Biotin, from the product label.

Global Healing Center

See all Global Healing Center products
Name
Global Healing Center, LP.
City
Houston
State
Texas
ZipCode
77018
Phone Number
1.800.476.0016
Web Address
www.globalhealingcenter.com
Pharmacist Counseling Corner

Biotin by Global Healing Center: Common Questions

Does Biotin by Global Healing Center interact with any medications?
Yes. Based on its ingredients, Biotin has a known interaction with 257 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Biotin contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is biotin safe during pregnancy?
Yes—biotin from food and prenatal vitamins is considered likely safe during pregnancy. But if you're taking a high-dose supplement like this one, discuss it with your doctor first to make sure the dose is right for you.
Will this help my hair or skin?
Biotin does work for biotin deficiency, which can affect hair and skin health. For other skin or hair concerns, the evidence we hold doesn't show biotin is effective. If that's why you're interested, talk with your doctor about whether you might have an actual biotin deficiency.
What is fulvic acid, and why is it in here?
Fulvic acid is an organic compound from decomposed plant and soil matter. It's included in this product, but the evidence we hold shows insufficient data to confirm it works for the conditions listed on the label—respiratory infections, lead exposure, eczema, fatigue, or hay fever.
What side effects should I watch for?
Fulvic acid may cause diarrhea, headache, or sore throat in some people. Biotin rarely causes mild diarrhea at high doses. If you develop any unusual symptoms, stop and tell your doctor.
Is this safe to take long-term?
Biotin is generally safe long-term. Fulvic acid appears tolerated in the short term, but good long-term safety data in humans is limited, so check with your doctor before using it for an extended period.
Can I take this if I'm breastfeeding?
Biotin in normal amounts is likely safe while breastfeeding, but the fulvic acid component lacks enough safety information, so the guidance is to avoid it. Talk with your doctor or pharmacist about whether this product is right for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Biotin is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Biotin label
Sources

Sources & How We Checked

Biotin's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 7 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Fulvic Acid 3 references
  1. Lu, FJ. Arsenic as a promoter in the effect of humic substances on plasma prothrombin time in vitro. Thromb Res 6-15-1990;58(6):537-541. PubMed
  2. Vucskits, AV, Hullar, I, Bersenyi, A, Andrasofszky, E, Kulcsar, M, Szabo, J. Effect of fulvic and humic acids on performance, immune response and thyroid function in rats. J Anim Physiol Anim Nutr (Berl) 2010;94(6):721-728. PubMed
  3. Gandy JJ, Meeding JP, Snyman JR, et al. Phase 1 clinical study of the acute and subacute safety and proof-of-concept efficacy of carbohydrate-derived fulvic acid. Clin Pharmacol. 2012;4:7-11. PubMed

See these in context on the Fulvic Acid monograph →

Biotin 4 references
  1. Debourdeau PM, Djezzar S, Estival JL, et al. Life-threatening eosinophilic pleuropericardial effusion related to vitamins B5 and H. Ann Pharmacother 2001;35:424-6. DOI
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  3. Mock DM, Quirk JG, Mock NI. Marginal biotin deficiency during normal pregnancy. Am J Clin Nutr 2002;75:295-9. PubMed
  4. Sedel F, Papeix C, Bellanger A, Touitou V, Lebrun-Frenay C, Galanaud D, et al. High doses of biotin in chronic progressive multiple sclerosis: a pilot study.Mult Scler Relat Disord. 2015;4(2):159-69. doi: 10.1016/j.msard.2015.01.005. PubMed

See these in context on the Biotin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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