No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Biotin Ingredients & Drug Interactions

by Nature's Bounty

Tablet Or Pill Category: Vitamin
No known interaction
The interaction bottom line No known interaction

Biotin is a dietary supplement by Nature's Bounty with 1 active ingredient. Its ingredients are commonly taken for hair growth and thinning hair, brittle nails, skin health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Biotin by Nature's Bounty

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: biotin. Biotin is a B vitamin your body uses to support hair, skin, and nail health, and it plays a role in how your cells convert food into energy.

The tablet also contains several inactive ingredients — calcium carbonate, dicalcium phosphate, microcrystalline cellulose, silicon dioxide, vegetable magnesium stearate, cross-linked cellulose gum, and cellulose gum — which are binders, fillers, and stabilizers used to form and preserve the tablet.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Biotin's overall clinical evidence instead.

Strong

Strong clinical evidence supports Biotin for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Biotin deficiency — rated "Likely Effective" (Natural Medicines).

Biotin is likely effective for biotin deficiency — the state where you don't get enough of this vitamin from food or your body can't absorb it well. For other uses, the evidence is weaker: it's rated possibly ineffective for multiple sclerosis and seborrheic dermatitis (a scalp condition), and there isn't enough reliable evidence to rate it for alopecia areata (patchy hair loss).

If you're taking biotin for hair, skin, or nails in the absence of a deficiency, talk with your doctor about whether the evidence supports it for your situation.

The evidence, ingredient by ingredient Biotin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Biotin is generally well tolerated, even at fairly high doses, because your body excretes excess amounts in your urine. High-dose biotin has rarely been linked to mild diarrhea — a small number of trial participants taking 300 mg daily reported this.

One case report describes a woman who developed a rare chest and heart lining inflammation after taking 10 mg biotin and other supplements together, but whether biotin was the cause remains unclear, and no similar cases have been reported since. Amounts from food and standard prenatal vitamins are appropriate; if you're considering a high-dose supplement, check with your doctor first.

Side effects, ingredient by ingredient Biotin

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we checked in this product. You're not at risk for biotin affecting how your medications work.

The bottom line

Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. No medication interactions are currently documented, and safety information is well characterized.

Biotin by Nature's Bounty is a straightforward B-vitamin supplement with no documented drug interactions. It's likely effective for biotin deficiency and is generally well tolerated.

If you're taking it for hair, skin, or nails without a known deficiency, talk with your doctor about whether the evidence supports that use for you. You don't need to worry about it conflicting with medications, but your pharmacist or doctor can confirm it fits your overall health plan.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 23, 2016.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Biotin, straight from the product label.

Brand Nature's Bounty
Barcode (UPC) 074312001055
Net contents 100 Tablet(s)
Market status On market
Date entered into DSLD Dec 23, 2016
DSLD ID 67560
Product type Vitamin
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Biotin by Nature's Bounty, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
UPC/BARCODE
074312001055
IngredientAmount% DV
Biotin1000 mcg333%

Other ingredients: Calcium Carbonate, Dicalcium Phosphate, Microcrystalline Cellulose, Silicon Dioxide, Vegetable Magnesium Stearate, cross linked Cellulose Gum, Cellulose Gum

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

WARNING: If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Keep out of reach of children.

not use if seal under cap is broken or missing.

Storage

Store at room temperature.

General Statements

Nutrition Questions or Comments? Call 1-800-433-2990 Mon. - Sat. 9 AM - 7 PM ET For educational health tips and savings join our e-newsletter, visit www.NaturesBounty.com

B

Coated for easy swallowing

Seals/Symbols

Guaranteed Quality Laboratory Tested

General

H3 7961 00A B7961

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

DIRECTIONS: For adults, take one (1) tablet daily, preferably with a meal.

Formulation

No Artificial Color, Flavor or Sweetener, No Preservatives, No Sugar, No Starch, No Milk, No Lactose, No Soy, No Gluten, No Wheat, No Yeast, No Fish. Sodium Free.

Suitable for Vegetarians

Brand IP Statement(s)

2016 Nature’s Bounty, Inc.

See for yourself

Biotin by Nature's Bounty label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Biotin by Nature's Bounty

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Amounts shown are per serving.

Biotin

No known
interactions
1000 mcg per serving Form: D-Biotin

Biotin (vitamin B7) is a water-soluble vitamin your body needs to turn food into energy and to support healthy hair, skin, and nails. Most people get...

Biotin monograph & interactions

Other (inactive) ingredients: Calcium Carbonate, Dicalcium Phosphate, Microcrystalline Cellulose, Silicon Dioxide, Vegetable Magnesium Stearate, Cross linked Cellulose Gum, Cellulose Gum. These complete the product’s ingredient list but are not active constituents.

Interaction report

Biotin by Nature's Bounty Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Biotin. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Biotin, from the product label.

Nature's Bounty

See all Nature's Bounty products
Name
Nature's Bounty, Inc.
City
Bohemia
State
NY
ZipCode
11716
Phone Number
1-800-433-2990
Web Address
www.NaturesBounty.com
Pharmacist Counseling Corner

Biotin by Nature's Bounty: Common Questions

Does Biotin by Nature's Bounty interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Biotin. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Biotin contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is biotin safe to take while I'm pregnant or breastfeeding?
Yes — biotin is rated likely safe during pregnancy and lactation. Normal dietary amounts and standard prenatal vitamins that contain biotin are appropriate. If you're considering a high-dose supplement beyond what's in prenatal vitamins, check with your doctor or midwife first.
What side effects should I watch for?
Biotin is generally very well tolerated. High-dose biotin (300 mg daily) has rarely caused mild diarrhea in a small number of people. One isolated case report described chest and heart lining inflammation in an older woman, but it's unclear whether biotin was responsible, and no similar cases have been reported.
Does biotin actually help with hair loss or thinning?
The evidence doesn't establish that biotin helps alopecia areata (patchy hair loss). For biotin deficiency — a lack of this vitamin — it is likely effective. If you're taking biotin for general hair health without a diagnosed deficiency, talk with your doctor about what the science supports.
Can I take this with my other supplements or medications?
No documented interactions are on file for biotin and medications. That said, absence of documented interactions isn't a guarantee none exist. Run your exact medication and supplement list through the checker on this page, or ask your pharmacist to review your full regimen.
Why would someone take biotin if they don't have a deficiency?
Many people take biotin hoping it will improve hair, skin, or nail appearance. The evidence for those uses is weak or not yet established in our data. If that's your reason, your doctor can help you decide whether it's worth trying based on your specific situation.
Is this product safe at high doses?
Biotin is well tolerated at high doses because your body removes excess through urine. That said, if you're thinking about taking a high-dose supplement, check with your doctor first — normal dietary and standard prenatal amounts are appropriate, but high-dose products warrant a conversation.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Biotin is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Biotin label
Go deeper

The Full Monographs Behind Biotin’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Biotin's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Biotin 4 references
  1. Debourdeau PM, Djezzar S, Estival JL, et al. Life-threatening eosinophilic pleuropericardial effusion related to vitamins B5 and H. Ann Pharmacother 2001;35:424-6. DOI
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  3. Mock DM, Quirk JG, Mock NI. Marginal biotin deficiency during normal pregnancy. Am J Clin Nutr 2002;75:295-9. PubMed
  4. Sedel F, Papeix C, Bellanger A, Touitou V, Lebrun-Frenay C, Galanaud D, et al. High doses of biotin in chronic progressive multiple sclerosis: a pilot study.Mult Scler Relat Disord. 2015;4(2):159-69. doi: 10.1016/j.msard.2015.01.005. PubMed

See these in context on the Biotin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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