No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Bittersweet 450 mg Ingredients & Drug Interactions

by TerraVita Premium Collection

Bittersweet 450 mg label
See full label image
Capsule Category: Botanical
No known interaction
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Bittersweet 450 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line No known interaction

Bittersweet 450 mg is a dietary supplement by TerraVita Premium Collection with 1 active ingredient. Its ingredients are commonly taken for skin conditions like eczema and warts, inflammation and joint discomfort, muscle spasms.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

Jump to a section

HelloPharmacist Scorecard of Bittersweet 450 mg by TerraVita Premium Collection

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: bittersweet nightshade at 450 mg per capsule. The capsules themselves are made with gelatin and water as inactive ingredients.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Bittersweet Nightshade product and its label doesn't state a use — see Bittersweet Nightshade's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for bittersweet nightshade doesn't establish that it works for any of the conditions it's been studied for — acne, eczema (atopic dermatitis), wound healing, and warts all have insufficient reliable evidence to rate. In other words, we don't have solid proof that it helps with these issues.

The evidence, ingredient by ingredient Bittersweet Nightshade

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Bittersweet nightshade contains toxic alkaloids and is not considered safe to take by mouth without medical supervision. The safety data we hold advises against its use.

When taken orally, the leaves and berries may cause serious and rare adverse effects including convulsions, gastrointestinal bleeding, circulatory depression, respiratory depression, and other symptoms like headache, speech difficulties, dilated pupils, and diarrhea. The pregnancy and lactation data rate bittersweet nightshade as likely unsafe in both situations.

Side effects, ingredient by ingredient Bittersweet Nightshade

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for this ingredient. However, because bittersweet nightshade carries toxicity concerns, you should still discuss this product with your pharmacist or doctor before starting it, especially if you take any medications.

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. No medication interactions are currently documented, and safety information is well characterized.

We can't recommend this product. Bittersweet nightshade carries real toxicity risks and lacks the safety data to support its use without medical supervision.

The evidence for its effectiveness is also insufficient. If you're interested in it for a specific skin or wound concern, talk with your pharmacist or doctor about safer, better-studied options.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 21, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Bittersweet 450 mg, straight from the product label.

Brand TerraVita Premium Collection
Barcode (UPC) 064435137588
Net contents 100 Capsule(s)
Market status On market
Date entered into DSLD Feb 21, 2023
DSLD ID 286678
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Bittersweet 450 mg by TerraVita Premium Collection, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
100
UPC/BARCODE
064435137588
IngredientAmount% DV
Bittersweet450 mg--

Other ingredients: Gelatin, Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

A Dietary Supplement

Brand IP Statement(s)

Copyright 2005 TerraVita - Distributed by ZooScape LLC, All Rights Reserved.

Suggested/Recommended/Usage/Directions

Directions Take 1 capsule 3 times daily, with meals.

General Statements

TerraVita is an exclusive line of premium natural products that use the finest, purest and most potent ingredients in the world. TerraVita's hallmarks are the highest possible standards of purity, potency, stability and freshness. All products are prepared with the greatest quality control, from raw materials through the entire manufacturing process, right up to the moment your product is sealed for freshness and shipped to you.

Please recycle!

FDA Disclaimer Statement

Statements not evaluated by FDA. Product not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Bittersweet 450 mg by TerraVita Premium Collection label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Bittersweet 450 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Bittersweet 450 mg by TerraVita Premium Collection

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container100 Amounts shown are per serving.

Bittersweet

No known
interactions
450 mg per serving

Bittersweet nightshade is a traditional herb with toxic compounds, especially in its berries, and there is very little reliable human evidence that it...

Bittersweet monograph & interactions

Other (inactive) ingredients: Gelatin, Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Bittersweet 450 mg by TerraVita Premium Collection Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Bittersweet 450 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Bittersweet 450 mg, from the product label.

TerraVita Premium Collection

See all TerraVita Premium Collection products
Name
TerraVita Fine Whole Herbs
City
Brampton
State
Ontario
Pharmacist Counseling Corner

Bittersweet 450 mg by TerraVita Premium Collection: Common Questions

Does Bittersweet 450 mg by TerraVita Premium Collection interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Bittersweet 450 mg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Bittersweet 450 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is bittersweet nightshade safe to take?
No. The safety data advises against it — the plant contains toxic alkaloids and is generally considered unsafe to take by mouth without medical supervision. There isn't reliable safety information available.
What are the side effects?
Serious adverse effects are rare but possible when taken orally, and can include convulsions, gastrointestinal bleeding, circulatory and respiratory depression, headache, speech difficulties, dilated pupils, diarrhea, and other symptoms. There's limited information about adverse effects from the stem specifically in medicinal amounts.
Can I take it if I'm pregnant or breastfeeding?
No. The data rates bittersweet nightshade as likely unsafe during both pregnancy and lactation.
Does it actually work for acne or eczema?
The evidence doesn't establish that it does. Acne, eczema (atopic dermatitis), wound healing, and warts all have insufficient reliable evidence to rate — meaning we don't have solid proof it helps with any of these issues.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Bittersweet 450 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Bittersweet 450 mg label
Go deeper

The Full Monographs Behind Bittersweet 450 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Bittersweet Nightshade

Bittersweet nightshade is a traditional herb with toxic compounds, especially in its berries, and there is very little reliable human evidence that it works for any health condition. Because...

Read the full Bittersweet Nightshade monograph →
Sources

Sources & How We Checked

Bittersweet 450 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 1 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bittersweet Nightshade 1 reference
  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.

See these in context on the Bittersweet Nightshade monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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