Interactions on record — worth a quick check against your medications. Based on 1 of 3 ingredients. Check your meds →
Dietary supplement

Bladder Restore Ingredients & Drug Interactions

by Ancestral Supplements

Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Minor
The interaction bottom line Most serious interaction: Minor

Bladder Restore is a dietary supplement by Ancestral Supplements with 3 active ingredients. Its ingredients are commonly taken for anemia and low iron, vitamin b12 support, general energy and fatigue.Based on those ingredients, 3 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Liver. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Bladder Restore by Ancestral Supplements

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Bladder Restore has 3 active ingredients: liver extract, kidney, and bladder. These are organ tissues intended to support bladder and urinary function — a practice rooted in traditional nutrition.

The product also contains gelatin as an inactive ingredient (the capsule material).

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: bladder and kidney support.
  • We looked for evidence on: urinary tract health, bladder function, kidney function.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

The evidence for liver extract in this product is limited. For chronic fatigue syndrome, liver extract rates as possibly ineffective.

For hepatitis C, there isn't enough reliable evidence to rate whether it works. The effectiveness of the kidney and bladder ingredients is not established in the data we hold.

The evidence, ingredient by ingredient Liver Extract

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

No adverse reactions have been formally reported, but a thorough safety study hasn't been done either. The bigger concern is source quality: liver extract comes from raw animal liver from slaughterhouses, and there's a theoretical risk of contamination from sick animals.

There's also concern about bovine spongiform encephalopathy (BSE) if the liver comes from countries where it's been reported — though no human cases from contaminated liver extract have been documented. Liver extract can deliver very high levels of vitamin A and iron, which matters if you're taking other sources of these nutrients or have conditions like iron overload.

Pregnant people should avoid this product unless their doctor advises otherwise, because high vitamin A can harm a developing baby.

Side effects, ingredient by ingredient Liver Extract

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Liver Extract.
  • The most serious interaction on file is rated Minor.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 3 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before starting Bladder Restore, double-check if you take warfarin (a blood thinner) or iron supplements or iron-containing medications. Both have minor interactions with the liver extract in this product.

Use the medication checker on this page to verify your specific drugs.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Only minor medication interactions are documented, and safety information is well characterized.

This product is for people interested in organ-based nutrition for bladder support. If you take warfarin or iron supplements, check with your pharmacist first — the liver extract can interfere with both.

Pregnant people and anyone with iron-overload conditions should talk to their doctor before using it. Source quality is also worth discussing with your pharmacist.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Bladder Restore, straight from the product label.

Brand Ancestral Supplements
Barcode (UPC) 850024798076
Net contents 180 Capsule(s)
Market status On market
Date entered into DSLD Oct 24, 2022
DSLD ID 275572
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Bladder Restore by Ancestral Supplements, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
6 Capsule(s)
Maximum serving Sizes:
6 Capsule(s)
Servings per container
30
UPC/BARCODE
850024798076
IngredientAmount% DV
Liver1000 mg--
Kidney1000 mg--
Bladder1000 mg--

Other ingredients: Gelatin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

For most of human history, we consumed the whole animal (nose-to-tail) with deep respect and profound purpose. For instance, Native Americans and early ancestral healers believed that eating the organs from a healthy animal would strengthen and support the health of the corresponding organ of the individual - also known as "like supports like." The traditional way of treating a person with a weak heart was to feed the person the heart of a healthy animal. Since we've abandoned these ways, the modern world has left us malnourished with an epidemic of declining health. The solution is to find ways to recreate our ancestral environment (sleep, nourishment, movement, sunshine, etc). It's time we honor our ancestors by putting back in, what the modern world has left out (to return our people back to strength, health and happiness). We walk our talk and we offer a one-of-a-kind "guided" experience. Learn more at www.ancestralsupplement.com Brian Johnson "Liver King"

One small batch at a time

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formula

Bladder with kidney and liver

180 capsules 500mg EA

Formulation

Pasture-raised in New Zealand & Australia Grass-fed & grass-finished

Hormone, pesticides & GMO free Absolutely no fillers (or) flow agents

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested use: 6 capsules daily or as directed by a healthcare professional

See for yourself

Bladder Restore by Ancestral Supplements label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Bladder Restore by Ancestral Supplements

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size6 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Liver

Interacts with
3 drugs
1000 mg per serving Form: Bovine

Liver extract is a dried or concentrated form of animal liver that is naturally rich in iron, vitamin B12, vitamin A, and other nutrients. It was once...

Liver monograph & interactions

Kidney

1000 mg per serving Form: Bovine

Bladder

1000 mg per serving Form: Bovine

Other (inactive) ingredients: Gelatin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Bladder Restore by Ancestral Supplements Drug Interactions

Want to check YOUR meds against Bladder Restore?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
3Drugs
3 Minor

Ingredients driving the most interactions

Liver 3

Each ingredient & the kinds of drugs it affects

For each ingredient in Bladder Restore with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Liver2 drug types · 3 drugs

Iron

Liver extract can contain heme iron. Taking liver extract with iron-containing medications or supplements may increase total iron intake and could increase the risk of gastrointestinal adverse effects or excessive iron accumulation. The risk is greater with high doses, prolonged use, or in individuals with hemochromatosis or another iron-overload disorder. Review the iron content of the liver extract and the total elemental iron dose. Avoid unnecessary duplicate iron supplementation and consider monitoring ferritin and transferrin saturation when clinically appropriate.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Liver extract products may contain small and variable amounts of vitamin K. Theoretically, starting, stopping, or substantially changing the amount of liver extract used could reduce the anticoagulant effect of warfarin and lower the INR. However, this interaction has not been directly studied or reported in humans, and the vitamin K content of liver extract products is generally not standardized. Consider monitoring the INR after a meaningful change in liver extract use.

Likelihood Possible Evidence C
The maker

Brand information

Manufacturer and brand details for Bladder Restore, from the product label.

Ancestral Supplements

See all Ancestral Supplements products
Name
Ancestral Supplements, LLC
City
Willis
State
TX
ZipCode
77318
Web Address
www.ancestralsupplements.com
Pharmacist Counseling Corner

Bladder Restore by Ancestral Supplements: Common Questions

Does Bladder Restore by Ancestral Supplements interact with any medications?
Yes. Based on its ingredients, Bladder Restore has a known interaction with 3 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Bladder Restore contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is liver extract safe during pregnancy?
No. Liver extract can contain very high levels of vitamin A, which may harm a developing baby. The safety data advises against it unless your doctor specifically says otherwise.
Can I take this if I have hemochromatosis or another iron-overload condition?
You should check with your doctor first. Liver extract contains heme iron, and adding it to your intake could increase the risk of excessive iron buildup in your body, especially with long-term use.
What are these organ ingredients supposed to do?
They're intended to support bladder and urinary function based on the idea that consuming organ tissues supports those organs — a traditional nutrition approach. However, we don't have established evidence that the kidney and bladder ingredients in this product are effective.
Have there been any reported side effects?
No adverse reactions have been formally reported. However, a full safety study hasn't been completed, and there are concerns about potential contamination from the liver extract's animal source.
Is this safe for long-term use?
Safety hasn't been well studied for extended use. Because liver extract can deliver high levels of vitamin A and iron, talk with your doctor before using it long-term, especially if you take other supplements or have conditions involving iron or vitamin A.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Bladder Restore label
Sources

Sources & How We Checked

Bladder Restore's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Liver Extract 4 references
  1. Lewis CJ. Letter to reiterate certain public health and safety concerns to firms manufacturing or importing dietary supplements that contain specific bovine tissues. FDA. Available at: www.cfsan.fda.gov/~dms/dspltr05.html.
  2. Kaslow JE, Rucker L, Onishi R. Liver extract-folic acid-cyanocobalamin vs placebo for chronic fatigue syndrome. Arch Intern Med 1989;149:2501-3. DOI
  3. Ebinuma, H., Saito, H., Tada, S., Masuda, T., Kamiya, T., Nishida, J., Yoshioka, M., and Ishii, H. Additive therapeutic effects of the liver extract preparation mixture adelavin-9 on interferon-beta treatment for chronic hepatitis C. Hepatogastroenterolog
  4. Saito, H., Ebinuma, H., Tada, S., Tsunematsu, S., Atsukawa, K., Masuda, T., Tsuchiya, M., and Ishii, H. Enhancing effect of the liver extract and flavin adenin dinucleotide mixture on anti-viral efficacy of interferon in patients with chronic hepatitis C. PubMed

See these in context on the Liver Extract monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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