No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Blood Root Vanilla Flavor Ingredients & Drug Interactions

by TerraVita

Liquid Category: Botanical
No known interaction
The interaction bottom line No known interaction

Blood Root Vanilla Flavor is a dietary supplement by TerraVita with 1 active ingredient. Its ingredients are commonly taken for skin growths, moles, and warts (topical), dental plaque and gum health, sore throat and cough (traditional).We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Blood Root Vanilla Flavor by TerraVita

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product has one active ingredient: a bloodroot glycerite liquid extract. Bloodroot is a plant extract that's been studied for use against dental plaque and gingivitis.

The inactive ingredients are glycerin and vanilla flavor.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: dental plaque and gum health.
  • We looked for evidence on: Dental plaque, Gingivitis, Periodontitis, oral health, periodontal health.
  • The strongest evidence on file: Bloodroot is rated "Possibly Effective" for Dental plaque (Natural Medicines).
  • Also on file: Bloodroot is rated "Possibly Effective" for Gingivitis.
  • Also on file: Bloodroot is rated "Insufficient Reliable Evidence To Rate" for Periodontitis.

Bloodroot has possibly effective evidence for reducing dental plaque and gingivitis. For periodontitis (gum disease affecting the bone underneath), there isn't enough reliable evidence yet to rate how well it works.

The evidence, ingredient by ingredient Bloodroot

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Here's where you need to pay close attention. Bloodroot is potentially toxic and corrosive, and we don't recommend it for self-treatment.

When taken by mouth in appropriate doses short-term, it's generally well tolerated — but nausea, vomiting, and central nervous system depression (drowsiness, sedation) have been reported. Higher doses can cause dangerously low blood pressure, shock, and even coma.

Long-term use of bloodroot toothpaste or mouthwash has been tied to mouth sores, taste changes, and staining of your tongue, teeth, and fillings. On skin, fresh bloodroot causes irritation or contact dermatitis; topical salves have caused severe pain, burning, skin erosion, and permanent scarring in people who've applied them for days at a time.

During pregnancy, bloodroot is likely unsafe because of potential toxicity and unestablished safety. While breastfeeding, there isn't enough safety data — avoid it.

Talk with your doctor or pharmacist before use.

Side effects, ingredient by ingredient Bloodroot

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. However, the serious safety profile of bloodroot itself — toxicity, corrosiveness, and risk of central nervous system depression at higher doses — means you should discuss this product with your pharmacist or doctor before starting it, regardless of your medications.

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Bloodroot has some evidence for dental plaque and gingivitis, but it carries real toxicity risks. We don't recommend self-treatment with it.

If you're considering this product, talk with your dentist or pharmacist first — the safety concerns outweigh the modest effectiveness data, and there are safer alternatives for your gums.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 13, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Blood Root Vanilla Flavor, straight from the product label.

Brand TerraVita
Barcode (UPC) 064435171551
Net contents 1 Fluid Ounce(s); 30 mL
Market status On market
Date entered into DSLD Dec 13, 2022
DSLD ID 281659
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Blood Root Vanilla Flavor by TerraVita, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
25 Drop(s)
Maximum serving Sizes:
40 Drop(s)
Servings per container
227
UPC/BARCODE
064435171551
IngredientAmount% DV
Bloodroot Glycerite Liquid Extract0.13 mL--

Other ingredients: Glycerin, Vanilla Flavor

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Copyright 2006 TerraVita - Distributed by ZooScape LLC, All Rights Reserved.

Formula

Glycerite liquid extract (1:5) Vanilla flavored

Formulation

Alcohol free

Suggested/Recommended/Usage/Directions

Suggested Use: Take 25-40 drops of extract in a small amount of warm water 3-4 times daily. Shake well before using.

Precautions

Keep away from children.

Do not use if safety seal around cap is broken or missing.

See for yourself

Blood Root Vanilla Flavor by TerraVita label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Blood Root Vanilla Flavor by TerraVita

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size25 Drop(s) Dosage formLiquid Servings per container227 Amounts shown are per serving.

Bloodroot Glycerite Liquid Extract

No known
interactions
0.13 mL per serving

Bloodroot is a North American plant whose red root sap contains potent alkaloids that are corrosive to skin and tissue. It has a long folk history, bu...

Bloodroot Glycerite Liquid Extract monograph & interactions

Other (inactive) ingredients: Glycerin, Vanilla Flavor. These complete the product’s ingredient list but are not active constituents.

Interaction report

Blood Root Vanilla Flavor by TerraVita Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Blood Root Vanilla Flavor. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Blood Root Vanilla Flavor, from the product label.

TerraVita

See all TerraVita products
Name
ZooScape LLC
Phone Number
844-449-0444
Web Address
www.ZooScape.com
Pharmacist Counseling Corner

Blood Root Vanilla Flavor by TerraVita: Common Questions

Does Blood Root Vanilla Flavor by TerraVita interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Blood Root Vanilla Flavor. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Blood Root Vanilla Flavor contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is bloodroot safe to use?
Bloodroot is potentially toxic and corrosive. When used by mouth in the right dose short-term, it's generally well tolerated, but nausea, vomiting, and drowsiness can happen. Higher doses carry serious risks including dangerously low blood pressure, shock, and coma. Long-term use in toothpastes or mouthwashes has caused mouth sores, taste changes, and tooth staining. We don't recommend it for self-treatment. Talk with your pharmacist or dentist.
Can I use this product while pregnant?
No. Bloodroot is likely unsafe during pregnancy because of potential toxicity and unestablished safety. Avoid it and talk with your doctor about safer options for your dental health.
Can I use this while breastfeeding?
The safety data advises against it. There isn't enough data on bloodroot's safety while breastfeeding, and there's potential for toxicity. Talk with your doctor or pharmacist about what's safe for you and your baby.
Does bloodroot actually work for gum disease?
There's possibly effective evidence that it helps with dental plaque and gingivitis. For periodontitis — deeper gum disease — there isn't enough reliable evidence yet to say how well it works.
What happens if I use too much bloodroot?
Higher doses can cause nausea, vomiting, central nervous system depression, dangerously low blood pressure, shock, and coma. This is why we don't recommend self-treatment with bloodroot — it has a narrow safety window.
Can I use this product if I have skin issues?
Don't apply bloodroot to your skin. Fresh bloodroot causes irritation and contact dermatitis. Topical bloodroot salves have caused severe pain, burning, skin erosion, and permanent scarring, especially when applied for several days in a row.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Blood Root Vanilla Flavor is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Blood Root Vanilla Flavor label
Go deeper

The Full Monographs Behind Blood Root Vanilla Flavor’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Blood Root Vanilla Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 17 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bloodroot 17 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  3. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  4. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  5. Tenenbaum, H., Dahan, M., and Soell, M. Effectiveness of a sanguinarine regimen after scaling and root planing. J Periodontol. 1999;70(3):307-311. PubMed
  6. Eversole, L. R., Eversole, G. M., and Kopcik, J. Sanguinaria-associated oral leukoplakia: comparison with other benign and dysplastic leukoplakic lesions. Oral Surg.Oral Med.Oral Pathol.Oral Radiol.Endod. 2000;89(4):455-464. PubMed
  7. Allen, C. L., Loudon, J., and Mascarenhas, A. K. Sanguinaria-related leukoplakia: epidemiologic and clinicopathologic features of a recently described entity. Gen.Dent. 2001;49(6):608-614.
  8. Kopczyk, R. A., Abrams, H., Brown, A. T., Matheny, J. L., and Kaplan, A. L. Clinical and microbiological effects of a sanguinaria-containing mouthrinse and dentifrice with and without fluoride during 6 months of use. J.Periodontol. 1991;62(10):617-622. PubMed
  9. Harper, D. S., Mueller, L. J., Fine, J. B., Gordon, J., and Laster, L. L. Clinical efficacy of a dentifrice and oral rinse containing sanguinaria extract and zinc chloride during 6 months of use. J.Periodontol. 1990;61(6):352-358. PubMed
  10. Kuftinec, M. M., Mueller-Joseph, L. J., and Kopczyk, R. A. Sanguinaria toothpaste and oral rinse regimen clinical efficacy in short- and long-term trials. J.Can.Dent.Assoc. 1990;56(7 Suppl):31-33.
  11. Frankos, V. H., Brusick, D. J., Johnson, E. M., Maibach, H. I., Munro, I., Squire, R. A., and Weil, C. S. Safety of Sanguinaria extract as used in commercial toothpaste and oral rinse products. J.Can.Dent.Assoc. 1990;56(7 Suppl):41-47.
  12. Cullinan, M. P., Powell, R. N., Faddy, M. J., and Seymour, G. J. Efficacy of a dentifrice and oral rinse containing sanguinaria extract in conjunction with initial periodontal therapy. Aust.Dent.J. 1997;42(1):47-51. PubMed
  13. Affleck, A. G. and Varma, S. A case of do-it-yourself Mohs' surgery using bloodroot obtained from the internet. Br.J Dermatol 2007;157(5):1078-1079. PubMed
  14. Cienki JJ, Zaret L. An Internet misadventure: bloodroot salve toxicity. J Altern Complement Med. 2010;16(10):1125-7. PubMed
  15. Hou JL, Brewer JD. Black salve and bloodroot extract in dermatologic conditions. Cutis. 2015;95(6):309-11.
  16. Schilling LM, Saedi N. Bloodroot paste: what dermatologists and patients need to know. Dermatol Surg 2016;42(10):1223-4. PubMed
  17. Schlichte MJ, Downing CP, Ramirez-Fort M, Gordon R, Tyring S. Bloodroot associated eschar. Dermatol Online J 2014;20(7). DOI

See these in context on the Bloodroot monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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