Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Osha Root Rocky Mountain Throat Syrup Ingredients & Drug Interactions

by Herbs, Etc.

Osha Root Rocky Mountain Throat Syrup label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Osha Root Rocky Mountain Throat Syrup against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Osha Root Rocky Mountain Throat Syrup is a dietary supplement by Herbs, Etc. with 1 active ingredient. Its ingredients are commonly taken for cough and sore throat, respiratory infections and colds, immune support.Based on those ingredients, 715 medications have a known interaction with it, the most serious rated moderate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Osha Root Rocky Mountain Throat Syrup by Herbs, Etc.

Ask about any prescription or over-the-counter medication and we check it for interactions with Osha Root Rocky Mountain Throat Syrup by Herbs, Etc. — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Osha Root Rocky Mountain Throat Syrup by Herbs, Etc.

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 5 active ingredients.
  • “Proprietary Extract Blend Ingredients” is a proprietary blend — the label gives one combined amount (10 mL) without saying how much of each component you get.
  • “Osha extract” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.

This liquid throat syrup contains five active herbal extracts. Black Cherry extract, White Pine extract, Spikenard extract, Balsam Poplar extract, and Bloodroot extract make up the formula, along with Osha extract (which itself is broken down into its own component ingredients).

The product also contains inactive ingredients — evaporated cane juice, purified water, vegetable glycerine, and U.S. Pharmacopoeial Alcohol — as a sweetener, solvent, and preservative base.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Respiratory health and throat comfort.
  • We looked for evidence on: Cough, Sore throat, Bronchitis, Respiratory infections.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

The evidence we hold doesn't establish how well this product works for sore throat or cough. We do have effectiveness ratings for Bloodroot extract alone, which is listed as possibly effective for dental plaque and gingivitis (gum inflammation), though the data on its use for periodontitis (deeper gum disease) is insufficient.

Since Bloodroot is only one of five ingredients in this syrup, those ratings don't tell us whether the formula as a whole will help your throat.

The evidence, ingredient by ingredient Osha

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Black Cherry extract in this product contains cyanide-forming compounds. Small amounts in commercial products are generally considered acceptable, but large doses can cause cyanide toxicity — a serious, potentially fatal condition.

Bloodroot is potentially toxic and corrosive; the safety data advises against using it for self-treatment. If you swallow large amounts of this syrup or use it long-term, talk to your pharmacist or doctor first.

Do not use this product during pregnancy or while breastfeeding — Black Cherry is likely unsafe in pregnancy, and Bloodroot is likely unsafe in pregnancy and possibly unsafe while nursing.

Side effects, ingredient by ingredient Osha

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 3 matched ingredients can interact with medications — American Spikenard, Wild Cherry.
  • The most serious interaction on file is rated Moderate.
  • For scale: 716 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this syrup, check whether you take any medications metabolized by the enzyme CYP3A4 — Black Cherry extract may increase their levels (Moderate severity). Examples include certain cholesterol drugs (lovastatin), antifungals (ketoconazole, itraconazole), and many others.

Use our medication checker below with your exact drugs to be sure.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This is a multi-ingredient herbal syrup with no proven effectiveness data in our records. It carries a moderate theoretical interaction risk with hundreds of common medications (especially those broken down by CYP3A4) and contains two ingredients — Black Cherry and Bloodroot — with significant safety warnings.

Check your medications with our tool before use, and talk to your pharmacist if you're pregnant, nursing, or planning long-term use.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 21, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Osha Root Rocky Mountain Throat Syrup, straight from the product label.

Brand Herbs, Etc.
Barcode (UPC) 765704125045
Net contents 4 Fluid Ounce(s); 118 mL
Market status On market
Date entered into DSLD Nov 21, 2018
DSLD ID 182969
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Children 4 or More Years of Age, Adult (18 - 50 Years), Gluten Free, Children more than 1 but less than 4
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Osha Root Rocky Mountain Throat Syrup by Herbs, Etc., sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.5 tsp
Maximum serving Sizes:
2 tsp
Servings per container
12
UPC/BARCODE
765704125045
IngredientAmount% DV
Calories20 Calorie(s)--
Proprietary Extract Blend Ingredients10 mL--
Osha extract0 NP--
White Pine extract0 NP--
Black Cherry extract0 NP--
Spikenard extract0 NP--
Balsam Poplar extract0 NP--
Bloodroot extract0 NP--

Other ingredients: Evaporated cane juice, purified Water, Vegetable Glycerine, U.S. Pharmacopoeial Alcohol

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Sinuses Throat Lungs Superb respiratory support In the great Southwest, the Native American and Hispanic cultures consider Osha root the must-have herb to maintain respiratory health.

Rocky Mountain Throat Syrup provides a protective coating that soothes and comforts tissues. It thins and liquefies thick mucus. This formula gently dilates the bronchioles and promotes sinus, throat, and lung health. Once you experience the benefits of Rocky Mountain Throat Syrup, you'll always make sure it's in your medicine cabinet.

Vibrant health begins with Herbs, Etc. True wellbeing starts when you choose to be responsible for your health. As you take your healthcare into your own hands, you become connected to your body and better able to listen to its needs. Herbs have to the ability to make significant shifts in your health. They are pivotal players in the healing process. The gift of medicinal herbs is their ability to restore and maintain vibrant health. Since 1969, Herbs, Etc. has been harnessing the healing power of nature to create safe and effective natural medicines. Join us on this great journey to health. facebook.com/herbsect Learn about Herbs, Etc.

Herbal medicine Professional strength Protective coating comforts the throat Soothing syrup with a deliciously powerful taste

Formula

Rocky Mountain Throat Syrup, featuring Osha root, has been cherished Herbs, Etc.'s formula for over 40 years.

General

ORRMTS032017

Brand IP Statement(s)

2017 Herbs, Etc., Inc.

Solutions you trust

FDA Statement of Identity

Herbal Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: Adults and children 12 years and over: 2 teaspoons every three hours. Children 5 to under 12 years of age: 1 teaspoon every three hours. Children 2 to under 5 years of age: 1/2 teaspoon every three hours. Children under 2 years of age: Ask your healthcare provider.

Precautions

Caution: Do not use during pregnancy.

Formulation

Gluten free

FDA Disclaimer Statement

This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Osha Root Rocky Mountain Throat Syrup by Herbs, Etc. label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Osha Root Rocky Mountain Throat Syrup label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Osha Root Rocky Mountain Throat Syrup by Herbs, Etc.

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.5 tsp Dosage formLiquid Servings per container12 Amounts shown are per serving.

Proprietary Extract Blend Ingredients

10 mL per serving

Other (inactive) ingredients: Evaporated cane juice, Purified Water, Vegetable Glycerine, U.S. Pharmacopoeial Alcohol. These complete the product’s ingredient list but are not active constituents.

Interaction report

Osha Root Rocky Mountain Throat Syrup by Herbs, Etc. Drug Interactions

Want to check YOUR meds against Osha Root Rocky Mountain Throat Syrup?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
715Drugs
643 Moderate 72 Minor

Ingredients driving the most interactions

Individual Drug Interactions

The ingredients in Osha Root Rocky Mountain Throat Syrup interact with 715 drugs. Click any drug to see the details.

0 of the 1 ingredient in Osha Root Rocky Mountain Throat Syrup interact with drugs. Each result below shows which ingredient is responsible.

Each ingredient & the kinds of drugs it affects

For each ingredient in Osha Root Rocky Mountain Throat Syrup with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

The maker

Brand information

Manufacturer and brand details for Osha Root Rocky Mountain Throat Syrup, from the product label.

Herbs, Etc.

See all Herbs, Etc. products
Name
Herbs, Etc., Inc.
Street Address
1340 Rufina Circle
City
Sante Fe
State
NM
ZipCode
87507
Web Address
www.herbsetc.com
Pharmacist Counseling Corner

Osha Root Rocky Mountain Throat Syrup by Herbs, Etc.: Common Questions

Does Osha Root Rocky Mountain Throat Syrup by Herbs, Etc. interact with any medications?
Yes. Based on its ingredients, Osha Root Rocky Mountain Throat Syrup has a known interaction with 715 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Osha Root Rocky Mountain Throat Syrup contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while I'm pregnant?
No — the safety data advises against it. Black Cherry extract is likely unsafe in pregnancy, and Bloodroot extract (also in this formula) is likely unsafe as well. Talk to your doctor or pharmacist before using any herbal product during pregnancy.
Is it safe to breastfeed while using this syrup?
The safety data advises against it. Black Cherry extract has not been adequately studied, and Bloodroot is possibly unsafe while breastfeeding. There isn't enough data to know it's safe, so discuss it with your pharmacist or doctor if you're nursing.
What's Bloodroot, and why is it in here?
Bloodroot is a plant extract we have data for; in our records, it's been tested for dental plaque and gingivitis (gum inflammation). However, the safety notes flag it as potentially toxic and not recommended for self-treatment, and the adverse effects include nausea, vomiting, and at high doses, serious complications like low blood pressure and loss of consciousness.
How much of this syrup is safe to take?
The product label should tell you the recommended dose. Because Black Cherry and Bloodroot both contain compounds that can be harmful in large amounts, don't exceed the directions on the bottle, and avoid long-term daily use without checking with your pharmacist first.
What's the Alcohol content in this?
The formula includes U.S. Pharmacopoeial Alcohol as part of the liquid base. The exact percentage isn't listed in the product facts we have, so check the label for the alcohol content if that matters to you.
Will this actually help my sore throat?
We don't have effectiveness data for this specific formula. The only ingredient we have effectiveness ratings for — Bloodroot — was tested for gum health, not sore throat. You'd want to talk with your pharmacist about whether this product is the right choice for your symptoms.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Osha Root Rocky Mountain Throat Syrup is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Osha Root Rocky Mountain Throat Syrup label
Go deeper

The Full Monographs Behind Osha Root Rocky Mountain Throat Syrup’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Osha

Osha is a root from a wild mountain plant native to the western United States and Mexico, traditionally used by Native American and Hispanic communities for coughs, colds, and sore throats....

Read the full Osha monograph →
Sources

Sources & How We Checked

Osha Root Rocky Mountain Throat Syrup's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 24 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Osha 2 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.

See these in context on the Osha monograph →

Wild Cherry 4 references
  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  2. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  3. Budzinski JW, Foster BC, Vandenhoek S, Arnason JT. An in vitro evaluation of human cytochrome P450 3A4 inhibition by selected commercial herbal extracts and tinctures. Phytomedicine 2000;7:273-82. PubMed
  4. Pentore, R., Venneri, A., and Nichelli, P. Accidental choke-cherry poisoning: early symptoms and neurological sequelae of an unusual case of cyanide intoxication. Ital.J Neurol.Sci. 1996;17(3):233-235. PubMed

See these in context on the Wild Cherry monograph →

American Spikenard 1 reference
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.

See these in context on the American Spikenard monograph →

Bloodroot 17 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  3. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  4. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  5. Tenenbaum, H., Dahan, M., and Soell, M. Effectiveness of a sanguinarine regimen after scaling and root planing. J Periodontol. 1999;70(3):307-311. PubMed
  6. Eversole, L. R., Eversole, G. M., and Kopcik, J. Sanguinaria-associated oral leukoplakia: comparison with other benign and dysplastic leukoplakic lesions. Oral Surg.Oral Med.Oral Pathol.Oral Radiol.Endod. 2000;89(4):455-464. PubMed
  7. Allen, C. L., Loudon, J., and Mascarenhas, A. K. Sanguinaria-related leukoplakia: epidemiologic and clinicopathologic features of a recently described entity. Gen.Dent. 2001;49(6):608-614.
  8. Kopczyk, R. A., Abrams, H., Brown, A. T., Matheny, J. L., and Kaplan, A. L. Clinical and microbiological effects of a sanguinaria-containing mouthrinse and dentifrice with and without fluoride during 6 months of use. J.Periodontol. 1991;62(10):617-622. PubMed
  9. Harper, D. S., Mueller, L. J., Fine, J. B., Gordon, J., and Laster, L. L. Clinical efficacy of a dentifrice and oral rinse containing sanguinaria extract and zinc chloride during 6 months of use. J.Periodontol. 1990;61(6):352-358. PubMed
  10. Kuftinec, M. M., Mueller-Joseph, L. J., and Kopczyk, R. A. Sanguinaria toothpaste and oral rinse regimen clinical efficacy in short- and long-term trials. J.Can.Dent.Assoc. 1990;56(7 Suppl):31-33.
  11. Frankos, V. H., Brusick, D. J., Johnson, E. M., Maibach, H. I., Munro, I., Squire, R. A., and Weil, C. S. Safety of Sanguinaria extract as used in commercial toothpaste and oral rinse products. J.Can.Dent.Assoc. 1990;56(7 Suppl):41-47.
  12. Cullinan, M. P., Powell, R. N., Faddy, M. J., and Seymour, G. J. Efficacy of a dentifrice and oral rinse containing sanguinaria extract in conjunction with initial periodontal therapy. Aust.Dent.J. 1997;42(1):47-51. PubMed
  13. Affleck, A. G. and Varma, S. A case of do-it-yourself Mohs' surgery using bloodroot obtained from the internet. Br.J Dermatol 2007;157(5):1078-1079. PubMed
  14. Cienki JJ, Zaret L. An Internet misadventure: bloodroot salve toxicity. J Altern Complement Med. 2010;16(10):1125-7. PubMed
  15. Hou JL, Brewer JD. Black salve and bloodroot extract in dermatologic conditions. Cutis. 2015;95(6):309-11.
  16. Schilling LM, Saedi N. Bloodroot paste: what dermatologists and patients need to know. Dermatol Surg 2016;42(10):1223-4. PubMed
  17. Schlichte MJ, Downing CP, Ramirez-Fort M, Gordon R, Tyring S. Bloodroot associated eschar. Dermatol Online J 2014;20(7). DOI

See these in context on the Bloodroot monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team