Yohimbe Bark Mint Flavor Ingredients & Drug Interactions
by TerraVita
What is this page for?
First and foremost: checking Yohimbe Bark Mint Flavor against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Yohimbe Bark Mint Flavor is a dietary supplement by TerraVita with 1 active ingredient. Its ingredients are commonly taken for erectile dysfunction, low sex drive, sexual performance.Based on those ingredients, 1,125 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Yohimbe Bark Glycerite Liquid Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Yohimbe Bark Mint Flavor by TerraVita
Ask about any prescription or over-the-counter medication and we check it for interactions with Yohimbe Bark Mint Flavor by TerraVita — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Yohimbe Bark Mint Flavor by TerraVita
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: yohimbe bark glycerite liquid extract. Yohimbine is the main active compound in yohimbe bark; it works as an alpha-2 adrenergic antagonist and has sympathomimetic properties (meaning it stimulates your nervous system in a way similar to adrenaline).
The product also contains glycerin and mint flavor as inactive ingredients that help with taste and preservation.
Does it work?
Insufficient evidence
The evidence for yohimbe bark is limited across the conditions it's marketed for. According to the data we hold, the evidence to rate its effectiveness for obesity, orthostatic hypotension (dizziness when standing), antidepressant-induced sexual dysfunction, and fatigue is insufficient.
That means the research available doesn't establish clear benefit for any of these uses—it's not that yohimbe doesn't work, just that strong evidence isn't available in the data we track.
How safe is it?
Well-documented data
Yohimbe can cause serious heart and blood pressure effects, and the amount of active ingredients in supplements is unpredictable from one batch to the next—that's a real safety concern. The most commonly reported side effects linked to yohimbine include anxiety, agitation, sweating, diarrhea, flushing, headache, high blood pressure, increased urination, nausea, rapid heartbeat, tremors, dizziness, and vomiting.
In rare cases, severe high blood pressure (hypertensive crisis) has been reported. You should avoid yohimbe during pregnancy—it may affect the uterus and is considered unsafe.
Avoid it while breastfeeding as well because safety hasn't been established.
Meds to double-check
Major interaction found
Before taking yohimbe, check with your pharmacist if you're on monoamine oxidase inhibitors (MAOIs)—this is a Major severity interaction. Also double-check blood pressure medications, tricyclic antidepressants, stimulant drugs, phenothiazines (antipsychotics), or any medications processed through your liver's CYP2D6 and CYP3A4 enzyme systems, as these carry Moderate severity interactions with yohimbe.
The bottom line
Scorecard at a glanceFully disclosed formula with insufficient evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.
Yohimbe is a potent herbal supplement with documented interactions affecting 1,113 individual medications across multiple drug types and serious potential side effects tied to heart function and blood pressure. If you take any prescription medication—especially blood pressure drugs, MAOIs, antidepressants, or stimulants—you need to check with your pharmacist before starting this product.
It's not appropriate during pregnancy or breastfeeding.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2022.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Yohimbe Bark Mint Flavor, straight from the product label.
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Yohimbe Bark Mint Flavor by TerraVita, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Yohimbe Bark Glycerite Liquid Extract | 0.13 mL | -- |
Other ingredients: Glycerin, Mint Flavor
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)
Copyright 2018 TerraVita - Distributed by ZooScape LLC, All Rights Reserved.
Formula
Glycerite liquid extract (1:5) Mint flavored
Formulation
Alcohol free
Suggested/Recommended/Usage/Directions
Suggested Use: Take 25-40 drops of extract in a small amount of warm water 3-4 times daily. Shake well before using.
Precautions
Keep away from children.
Do not use if safety seal around cap is broken or missing.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Yohimbe Bark Mint Flavor by TerraVita label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Yohimbe Bark Mint Flavor by TerraVita
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size25 Drop(s) Dosage formLiquid Servings per container227 Amounts shown are per serving.
Yohimbe Bark Glycerite Liquid Extract
Interacts with1,125 drugs
Yohimbe is a West African tree bark that contains yohimbine, a compound mainly promoted for erectile dysfunction and as an aphrodisiac. A prescription...
Yohimbe Bark Glycerite Liquid Extract monograph & interactionsOther (inactive) ingredients: Glycerin, Mint Flavor. These complete the product’s ingredient list but are not active constituents.
Yohimbe Bark Mint Flavor by TerraVita Drug Interactions
HelloPharmacist Interaction Report
Yohimbe Bark Mint Flavor by TerraVita contains yohimbe bark, which has documented interactions with a number of medications—most notably monoamine oxidase inhibitors (MAOIs).
Using yohimbe with MAOIs can cause additive effects and raise serious safety concerns; this is a Major severity interaction. The product also interacts moderately with blood pressure medications, certain antidepressants (tricyclic antidepressants), stimulant drugs, and several other drug types processed by your liver's enzyme systems.
Read the full breakdown — every affected drug type, severity by severity
Yohimbe may reduce how well blood pressure medications work because its active compound (yohimbine) can raise your blood pressure. It also interacts moderately with tricyclic antidepressants—clinical research shows yohimbine can trigger severe anxiety, agitation, and tremor in people taking these drugs.
Stimulant medications (including some decongestants and ADD drugs) could have additive effects when combined with yohimbe, as could phenothiazines (older antipsychotic drugs). Additionally, certain drugs processed through your liver's CYP2D6 and CYP3A4 pathways may be affected—yohimbine can inhibit these enzymes or have its own levels raised by other enzyme inhibitors.
Although we have no documented interactions with other ingredients in this product beyond yohimbe bark, you should run your exact medications through the search tool on this page before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Yohimbe Bark Mint Flavor?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Yohimbe Bark Mint Flavor interact with 1,125 drugs. Click any drug to see the details.
1 of the 1 ingredient in Yohimbe Bark Mint Flavor interact with drugs. Each result below shows which ingredient is responsible. Yohimbe Bark Glycerite Liquid Extract
AmphetamineAdensys XR-ODT, Adzenys ER, Dyanavel XR, Mydayis
How Amphetamine interacts with Yohimbe Bark Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Yohimbe Bark Glycerite Liquid ExtractCytochrome P450 2d6 (cyp2d6) Substrates, Stimulant Drugs +1 Major
Interaction Summary
Theoretically, yohimbe might increase the levels and adverse effects of CYP2D6 substrates.
Read the full Yohimbe Bark Glycerite Liquid Extract + Amphetamine interactionIsocarboxazidMarplan
How Isocarboxazid interacts with Yohimbe Bark Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Yohimbe Bark Glycerite Liquid ExtractMonoamine Oxidase Inhibitors (maois) Major
Interaction Summary
Concomitant use of MAOIs with yohimbe can result in additive effects.
Read the full Yohimbe Bark Glycerite Liquid Extract + Isocarboxazid interactionMoclobemideManerix, Moclobemide
How Moclobemide interacts with Yohimbe Bark Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Yohimbe Bark Glycerite Liquid ExtractCytochrome P450 2d6 (cyp2d6) Inhibitors, Monoamine Oxidase Inhibitors (maois) Major
Interaction Summary
CYP2D6 inhibitors may increase the levels and adverse effects of yohimbine, a constituent of yohimbe.
Read the full Yohimbe Bark Glycerite Liquid Extract + Moclobemide interactionOzanimod HydrochlorideZeposia
How Ozanimod Hydrochloride interacts with Yohimbe Bark Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Yohimbe Bark Glycerite Liquid ExtractMonoamine Oxidase Inhibitors (maois) Major
Interaction Summary
Concomitant use of MAOIs with yohimbe can result in additive effects.
Read the full Yohimbe Bark Glycerite Liquid Extract + Ozanimod Hydrochloride interactionPhenelzine SulfateNardil
How Phenelzine Sulfate interacts with Yohimbe Bark Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Yohimbe Bark Glycerite Liquid ExtractMonoamine Oxidase Inhibitors (maois) Major
Interaction Summary
Concomitant use of MAOIs with yohimbe can result in additive effects.
Read the full Yohimbe Bark Glycerite Liquid Extract + Phenelzine Sulfate interactionRasagilineAzilect
How Rasagiline interacts with Yohimbe Bark Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Yohimbe Bark Glycerite Liquid ExtractMonoamine Oxidase Inhibitors (maois), Cytochrome P450 1a2 (cyp1a2) Substrates Major
Interaction Summary
Concomitant use of MAOIs with yohimbe can result in additive effects.
Read the full Yohimbe Bark Glycerite Liquid Extract + Rasagiline interactionSafinamide MesylateXadago
How Safinamide Mesylate interacts with Yohimbe Bark Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Yohimbe Bark Glycerite Liquid ExtractMonoamine Oxidase Inhibitors (maois) Major
Interaction Summary
Concomitant use of MAOIs with yohimbe can result in additive effects.
Read the full Yohimbe Bark Glycerite Liquid Extract + Safinamide Mesylate interactionSelegilineCarbex, Eldepryl, Emsam, Zelapar
How Selegiline interacts with Yohimbe Bark Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Yohimbe Bark Glycerite Liquid ExtractMonoamine Oxidase Inhibitors (maois) Major
Interaction Summary
Concomitant use of MAOIs with yohimbe can result in additive effects.
Read the full Yohimbe Bark Glycerite Liquid Extract + Selegiline interactionTranylcypromineParnate
How Tranylcypromine interacts with Yohimbe Bark Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Yohimbe Bark Glycerite Liquid ExtractMonoamine Oxidase Inhibitors (maois) Major
Interaction Summary
Concomitant use of MAOIs with yohimbe can result in additive effects.
Read the full Yohimbe Bark Glycerite Liquid Extract + Tranylcypromine interactionAbametapirXeglyze
How Abametapir interacts with Yohimbe Bark Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Yohimbe Bark Glycerite Liquid ExtractCytochrome P450 3a4 (cyp3a4) Inhibitors Moderate
Interaction Summary
Theoretically, CYP3A4 inhibitors might increase the levels and adverse effects of yohimbine, a constituent of yohimbe bark.
Read the full Yohimbe Bark Glycerite Liquid Extract + Abametapir interactionAbiraterone
How Abiraterone interacts with Yohimbe Bark Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Yohimbe Bark Glycerite Liquid ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 3a4 (cyp3a4) Inhibitors +1 Moderate
Interaction Summary
Theoretically, yohimbe might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Yohimbe Bark Glycerite Liquid Extract + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Yohimbe Bark Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Yohimbe Bark Glycerite Liquid ExtractCytochrome P450 2d6 (cyp2d6) Inhibitors, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
CYP2D6 inhibitors may increase the levels and adverse effects of yohimbine, a constituent of yohimbe.
Read the full Yohimbe Bark Glycerite Liquid Extract + Abiraterone Acetate interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Yohimbe Bark Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Yohimbe Bark Glycerite Liquid ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, yohimbe might reduce the effects of antihypertensive drugs.
Read the full Yohimbe Bark Glycerite Liquid Extract + Acebutolol interactionAcepromazineAtravet
How Acepromazine interacts with Yohimbe Bark Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Yohimbe Bark Glycerite Liquid ExtractPhenothiazines Moderate
Interaction Summary
Theoretically, using yohimbine with phenothiazines might have additive effects.
Read the full Yohimbe Bark Glycerite Liquid Extract + Acepromazine interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Yohimbe Bark Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Yohimbe Bark Glycerite Liquid ExtractAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates +2 Moderate
Interaction Summary
Theoretically, combining yohimbe bark with antiplatelet or anticoagulant drugs might have additive effects; however, this has not been reported in clinical research.
Read the full Yohimbe Bark Glycerite Liquid Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Yohimbe Bark Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Yohimbe Bark Glycerite Liquid ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Stimulant Drugs Moderate
Interaction Summary
Theoretically, yohimbe might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Yohimbe Bark Glycerite Liquid Extract + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Yohimbe Bark Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Yohimbe Bark Glycerite Liquid ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, yohimbe might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Yohimbe Bark Glycerite Liquid Extract + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Yohimbe Bark Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Yohimbe Bark Glycerite Liquid ExtractStimulant Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates +2 Moderate
Interaction Summary
Theoretically, taking yohimbe with stimulant drugs can have additive effects.
Read the full Yohimbe Bark Glycerite Liquid Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Yohimbe Bark Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Yohimbe Bark Glycerite Liquid ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, yohimbe might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Yohimbe Bark Glycerite Liquid Extract + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Yohimbe Bark Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Yohimbe Bark Glycerite Liquid ExtractCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, yohimbe might increase the levels and adverse effects of CYP2D6 substrates.
Read the full Yohimbe Bark Glycerite Liquid Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Yohimbe Bark Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Yohimbe Bark Glycerite Liquid ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +3 Moderate
Interaction Summary
Theoretically, yohimbe might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Yohimbe Bark Glycerite Liquid Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Yohimbe Bark Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Yohimbe Bark Glycerite Liquid ExtractCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +2 Moderate
Interaction Summary
Theoretically, yohimbe might increase the levels and adverse effects of CYP2D6 substrates.
Read the full Yohimbe Bark Glycerite Liquid Extract + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Yohimbe Bark Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Yohimbe Bark Glycerite Liquid ExtractStimulant Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates +2 Moderate
Interaction Summary
Theoretically, taking yohimbe with stimulant drugs can have additive effects.
Read the full Yohimbe Bark Glycerite Liquid Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Yohimbe Bark Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Yohimbe Bark Glycerite Liquid ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +2 Moderate
Interaction Summary
Theoretically, yohimbe might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Yohimbe Bark Glycerite Liquid Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Yohimbe Bark Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Yohimbe Bark Glycerite Liquid ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, yohimbe might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Yohimbe Bark Glycerite Liquid Extract + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Yohimbe Bark Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Yohimbe Bark Glycerite Liquid ExtractStimulant Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, taking yohimbe with stimulant drugs can have additive effects.
Read the full Yohimbe Bark Glycerite Liquid Extract + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Yohimbe Bark Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Yohimbe Bark Glycerite Liquid ExtractCytochrome P450 2d6 (cyp2d6) Inhibitors, Cytochrome P450 2d6 (cyp2d6) Substrates +2 Moderate
Interaction Summary
CYP2D6 inhibitors may increase the levels and adverse effects of yohimbine, a constituent of yohimbe.
Read the full Yohimbe Bark Glycerite Liquid Extract + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Yohimbe Bark Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Yohimbe Bark Glycerite Liquid ExtractStimulant Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates +3 Moderate
Interaction Summary
Theoretically, taking yohimbe with stimulant drugs can have additive effects.
Read the full Yohimbe Bark Glycerite Liquid Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Yohimbe Bark Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Yohimbe Bark Glycerite Liquid ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2d6 (cyp2d6) Inhibitors +2 Moderate
Interaction Summary
Theoretically, yohimbe might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Yohimbe Bark Glycerite Liquid Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Yohimbe Bark Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Yohimbe Bark Glycerite Liquid ExtractCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 2d6 (cyp2d6) Inhibitors +2 Moderate
Interaction Summary
Theoretically, yohimbe might increase the levels and adverse effects of CYP2D6 substrates.
Read the full Yohimbe Bark Glycerite Liquid Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Yohimbe Bark Mint Flavor with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Yohimbe Bark Glycerite Liquid Extract
Monoamine Oxidase Inhibitors (Maois)
Concomitant use of MAOIs with yohimbe can result in additive effects.
Yohimbine, a constituent of yohimbe, has MAO inhibitory effects. At high doses, yohimbine is a non-selective inhibitor of MAO.
Antihypertensive Drugs
Theoretically, yohimbe might reduce the effects of antihypertensive drugs.
Yohimbine, a constituent of yohimbe, is an alpha-2 adrenoceptor antagonist and has been reported to increase blood pressure in clinical research. Theoretically, concomitant use of yohimbe and antihypertensive drugs can interfere with blood pressure control.
Clonidine (Catapres)
Theoretically, yohimbe might precipitate clonidine withdrawal.
Chronic clonidine use can downregulate alpha-2 adrenoreceptors. Animal research and one human case report suggest that concomitant administration of yohimbine, an alpha-2 adrenoceptor antagonist, may precipitate clonidine withdrawal and lead to sympathomimetic toxicity, including hypertensive crisis.
Cytochrome P450 2D6 (Cyp2D6) Inhibitors
CYP2D6 inhibitors may increase the levels and adverse effects of yohimbine, a constituent of yohimbe.
In vitro and clinical research shows that the yohimbe bark constituent, yohimbine, is metabolized by CYP2D6 isoenzymes. Paroxetine, a cytochrome P450 (CYP) 2D6 inhibitor, increases the maximum serum concentration of yohimbine and reduces the clearance of yohimbine compared to yohimbine alone in patients who are extensive CYP2D6 metabolizers..
Cytochrome P450 2D6 (Cyp2D6) Substrates
Theoretically, yohimbe might increase the levels and adverse effects of CYP2D6 substrates.
In vitro research suggests that yohimbine, a constituent of yohimbe bark, inhibits CYP2D6 enzyme activity.
Cytochrome P450 3A4 (Cyp3A4) Inhibitors
Theoretically, CYP3A4 inhibitors might increase the levels and adverse effects of yohimbine, a constituent of yohimbe bark.
In vitro and clinical research shows that the yohimbe bark constituent, yohimbine, is metabolized by CYP3A4 enzymes. Theoretically, drugs that inhibit CYP3A4 might increase the levels and adverse effects of yohimbine.
Paroxetine (Paxil)
Paroxetine decreases the clearance of yohimbine and may increase its effects.
Paroxetine, a cytochrome P450 (CYP) 2D6 inhibitor, increases the maximum serum concentration of yohimbine by about 350% and reduces the clearance of yohimbine by about 80% compared to yohimbine alone in patients who are extensive CYP2D6 metabolizers. No significant changes in pharmacokinetic parameters of yohimbine were observed with coadministration of paroxetine in patients who are poor CYP2D6 metabolizers.
Phenothiazines
Theoretically, using yohimbine with phenothiazines might have additive effects.
Yohimbine, a constituent of yohimbe, has alpha-2 adrenergic antagonist effects. Theoretically, combining it with phenothiazines can cause additive alpha-2 adrenergic antagonism.
Stimulant Drugs
Theoretically, taking yohimbe with stimulant drugs can have additive effects.
Yohimbine, a constituent of yohimbe, has sympathomimetic effects and increases blood pressure in a dose-dependent manner. Theoretically, taking yohimbe with stimulant drugs can have additive stimulant and hypertensive effects.
Tricyclic Antidepressants (Tcas)
Theoretically, taking yohimbe with TCAs can increase adverse effects.
A small clinical study in patients taking TCAs for at least 4 weeks shows that receiving doses of intravenous yohimbine 2.5-20 mg daily for up to 7 days precipitates severe anxiety, agitation, and tremor. The effects of yohimbe bark itself are unclear; oral yohimbe bark contains 0.6% to 1.38% yohimbine, but it is unclear how much is absorbed.
Anticoagulant/Antiplatelet Drugs
Theoretically, combining yohimbe bark with antiplatelet or anticoagulant drugs might have additive effects; however, this has not been reported in clinical research.
Research in healthy adults shows that taking yohimbine, a constituent of yohimbe bark, in doses of 8 mg or more, seems to inhibit platelet aggregation in vitro by binding to the alpha-2 adrenoceptor. The effects of yohimbe bark itself are unclear; yohimbe bark contains 0.6% to 1.38% yohimbine, but it is unclear how much is absorbed.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, yohimbe might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that yohimbe extract induces CYP1A2 enzymes.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, yohimbe might decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that yohimbe extract induces CYP3A4 enzymes.
Brand information
Manufacturer and brand details for Yohimbe Bark Mint Flavor, from the product label.
TerraVita
See all TerraVita products- Name
- ZooScape LLC
- Phone Number
- 844-449-0444
- Web Address
- www.ZooScape.com
Yohimbe Bark Mint Flavor by TerraVita: Common Questions
Does Yohimbe Bark Mint Flavor by TerraVita interact with any medications?
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Yohimbe Bark Mint Flavor’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Yohimbe Bark Mint Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 66 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Yohimbe 66 references
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC