Branched Chain Amino Acid Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Branched Chain Amino Acid against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Branched Chain Amino Acid is a dietary supplement by Douglas Laboratories with 4 active ingredients. Its ingredients are commonly taken for general amino acid/protein support, muscle and tissue health, immune support.Based on those ingredients, 3 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are L-Threonine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Branched Chain Amino Acid by Douglas Laboratories
Ask about any prescription or over-the-counter medication and we check it for interactions with Branched Chain Amino Acid by Douglas Laboratories — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Branched Chain Amino Acid by Douglas Laboratories
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains 4 active ingredients: three branched-chain amino acids (L-Leucine, L-Isoleucine, and L-Valine) and L-Threonine, all delivered in capsule form. The inactive ingredients are gelatin, cellulose, vegetable stearate, and silica — these are standard fillers and binders that hold the capsule together.
Does it work?
Couldn't assess
The evidence for these ingredients is limited. L-Threonine has been studied for several neurological conditions: it's rated possibly ineffective for ALS (Lou Gehrig's disease), and there isn't enough reliable evidence to rate it for multiple sclerosis, familial spastic paraparesis, or spasticity.
We don't have effectiveness data on file for the other three amino acids in this product.
How safe is it?
Well-documented data
Threonine from food is fine, but supplements at higher doses haven't been well studied. The main side effects reported are headache and mild stomach upset, including diarrhea, gas, or constipation in some people.
For pregnancy and breastfeeding, food amounts of threonine are normal, but supplement use at higher doses hasn't been well studied — talk with your doctor or pharmacist before taking this if you're pregnant or nursing. We don't have safety data on file for L-Leucine, L-Isoleucine, or L-Valine.
Meds to double-check
Major interaction found
Check your medications against our tool if you're on an NMDA antagonist — threonine may reduce how well it works. We couldn't check the other three amino acids in this product, so if you're on any medication, it's worth a full review with your pharmacist.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Major medication interactions have been identified, and safety information is well characterized.
This is a branched-chain amino acid blend with one ingredient that may interact with NMDA antagonist medications. If you're on any prescription drugs, check them against our tool first.
Talk with your pharmacist about whether this is right for your situation, especially if you're pregnant, nursing, or taking neurological medications.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2012.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Branched Chain Amino Acid, straight from the product label.
| Brand | Douglas Laboratories |
|---|---|
| Barcode (UPC) | 310539036686 |
| Net contents | 120 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Feb 23, 2012 |
| DSLD ID | 5380 |
| Product type | Amino Acid/protein |
| Supplement form | Capsule |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Branched Chain Amino Acid by Douglas Laboratories, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| L-Leucine | 300 mg | -- |
| L-Isoleucine | 150 mg | -- |
| L-Valine | 150 mg | -- |
| L-Threonine | 10 mg | -- |
Other ingredients: Gelatin, Cellulose, Vegetable Stearate, Silica
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested Usage: As a dietary supplement, adults take 1-4 capsules daily or as directed by your healthcare professional.
Precautions
KEEP OUT OF REACH OF CHILDREN.
Tamper resistant package, do not use if outer seal is missing.
Storage
For optimal storage conditions, store in a cool, dry place. (59(0)-77(0)F/15(0)-25(0)C) (35-65% relative humidity)
General Statements
A Dietary Supplement
General
Formula #200903
Formulation
This product contains NO yeast, wheat gluten, soy protein, milk/dairy, corn, sodium, sugar, starch, artificial coloring, preservatives or flavoring.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Branched Chain Amino Acid by Douglas Laboratories label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Branched Chain Amino Acid by Douglas Laboratories
These are the 4 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container120 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
L-Leucine
L-Isoleucine
L-Valine
L-Threonine
Interacts with3 drugs
Threonine is an essential amino acid your body needs but cannot make, so you must get it from food or supplements. Most people get plenty from a norma...
L-Threonine monograph & interactionsOther (inactive) ingredients: Gelatin, Cellulose, Vegetable Stearate, Silica. These complete the product’s ingredient list but are not active constituents.
Branched Chain Amino Acid by Douglas Laboratories Drug Interactions
HelloPharmacist Interaction Report
Branched Chain Amino Acid by Douglas Laboratories contains one ingredient with a documented interaction: L-Threonine.
It may theoretically decrease the effects of NMDA antagonists (a class of medications that block a specific type of brain receptor). Threonine raises levels of glycine in the central nervous system, and glycine enhances how these receptors work, which could potentially reduce how well the medication performs.
Read the full breakdown — every affected drug type, severity by severity
The other three active ingredients — L-Leucine, L-Isoleucine, and L-Valine — we were unable to check for interactions because we hold no interaction data for them.
Altogether, these interactions span 3 individual medications. Before you start this supplement, especially if you're on any prescription medication, run it through the interaction checker on this page with your exact drug names.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Branched Chain Amino Acid?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Branched Chain Amino Acid interact with 3 drugs. Click any drug to see the details.
1 of the 4 ingredients in Branched Chain Amino Acid interact with drugs. Each result below shows which ingredient is responsible. L-Threonine
MemantineEbixa
How Memantine interacts with Branched Chain Amino Acid — through 1 ingredient. Tap an ingredient for the detail:
L-threonineNmda Antagonists Major
Interaction Summary
Theoretically, threonine might decrease the effects of NMDA antagonists.
Read the full L-threonine + Memantine interactionMemantine HydrochlorideNamenda
How Memantine Hydrochloride interacts with Branched Chain Amino Acid — through 1 ingredient. Tap an ingredient for the detail:
L-threonineNmda Antagonists Major
Interaction Summary
Theoretically, threonine might decrease the effects of NMDA antagonists.
Read the full L-threonine + Memantine Hydrochloride interactionMemantine, DonepezilNamzaric
How Memantine, Donepezil interacts with Branched Chain Amino Acid — through 1 ingredient. Tap an ingredient for the detail:
L-threonineNmda Antagonists Major
Interaction Summary
Theoretically, threonine might decrease the effects of NMDA antagonists.
Read the full L-threonine + Memantine, Donepezil interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Branched Chain Amino Acid with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
L-Threonine
Nmda Antagonists
Theoretically, threonine might decrease the effects of NMDA antagonists.
Threonine increases central nervous system (CNS) glycine levels. Glycine seems to bind a site on NMDA receptors and enhance the activity of the receptors.
Brand information
Manufacturer and brand details for Branched Chain Amino Acid, from the product label.
Douglas Laboratories
See all Douglas Laboratories products- Name
- Douglas Laboratories
- Street Address
- 600 Boyce Road
- City
- Pittsburgh
- State
- PA
- ZipCode
- 15205
- Phone Number
- 1.800.245.4440
- Web Address
- www.douglaslabs.com
Branched Chain Amino Acid by Douglas Laboratories: Common Questions
Does Branched Chain Amino Acid by Douglas Laboratories interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is threonine safe to take as a supplement?
Can I take this if I'm pregnant or breastfeeding?
What are branched-chain amino acids, and what do they do?
Does this product work for multiple sclerosis or spasticity?
What inactive ingredients are in this?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Branched Chain Amino Acid is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Branched Chain Amino Acid’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Branched Chain Amino Acid's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 4 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Threonine 4 references
- Tandan R, Bromberg MB, Forshew D, et al. A controlled trial of amino acid therapy in amyotrophic lateral sclerosis: I. Clinical, functional, and maximum isometric torque data. Neurology 1996;47:1220-6. PubMed
- Lee A, Patterson V. A double blind study of L-threonine in patients with spinal spasticity. Acta Neurol Scand 1993;88:334-8. PubMed
- Blin O, Pouget J, Aubrespy G, et al. A double-blind placebo controlled trial of L-threonine in amyotrophic lateral sclerosis. J Neurol 1992;239:79-81.
- Roufs JB. L-threonine as a symptomatic treatment for amyotrophic lateral sclerosis (ALS). Med Hypotheses 1991;34:20-3. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC