Branched Chain Amino Acids Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Branched Chain Amino Acids against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Branched Chain Amino Acids is a dietary supplement by Douglas Laboratories with 4 active ingredients. Its ingredients are commonly taken for general amino acid/protein support, muscle and tissue health, immune support.Based on those ingredients, 3 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are L-Threonine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Branched Chain Amino Acids by Douglas Laboratories
Ask about any prescription or over-the-counter medication and we check it for interactions with Branched Chain Amino Acids by Douglas Laboratories — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Branched Chain Amino Acids by Douglas Laboratories
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains 4 branched chain amino acids: L-Leucine, L-Isoleucine, L-Valine, and L-Threonine. These are amino acids your body uses to build and repair muscle and other tissues.
The capsule also contains inactive ingredients — cellulose, gelatin, and vegetable stearate — that help form and deliver the capsule.
Does it work?
Couldn't assess
The evidence for threonine alone in treating muscle and nerve conditions is limited or mixed. For ALS (Lou Gehrig's disease), the data we hold suggests it's possibly ineffective.
For multiple sclerosis, familial spastic paraparesis, and spasticity, we don't have enough reliable evidence to rate whether it works. The data we hold does not include effectiveness ratings for the other three amino acids in this product.
How safe is it?
Well-documented data
Threonine from food is well tolerated, but supplement safety at higher doses hasn't been well studied. Some people taking threonine supplements have reported headache and minor stomach upset, including diarrhea, gas, or constipation.
The safety data advises against threonine supplements in pregnancy and breastfeeding unless a clinician advises otherwise, since supplement use at these times hasn't been well studied. Talk with your pharmacist or doctor if you're pregnant, planning to become pregnant, or breastfeeding.
Meds to double-check
Major interaction found
Check any NMDA antagonists you may be taking before you add this product — threonine may reduce their effectiveness. We could not check three of the four ingredients in this supplement, so discuss your full medication list with your pharmacist.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Major medication interactions have been identified, and safety information is well characterized.
This is a branched chain amino acid blend — useful for people who want to support muscle and tissue repair. Anyone taking NMDA antagonists should check their exact medication with your pharmacist first.
If you're pregnant, breastfeeding, or taking any prescription drugs, have that conversation before you start.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 1, 2012.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Branched Chain Amino Acids, straight from the product label.
| Brand | Douglas Laboratories |
|---|---|
| Barcode (UPC) | 310539003299 |
| Net contents | 100 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Jun 1, 2012 |
| DSLD ID | 8825 |
| Product type | Amino Acid/protein |
| Supplement form | Capsule |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years), Dairy Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Branched Chain Amino Acids by Douglas Laboratories, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| L-Leucine | 150 mg | -- |
| L-Isoleucine | 150 mg | -- |
| L-Valine | 150 mg | -- |
| L-Threonine | 10 mg | -- |
Other ingredients: Cellulose, Gelatin, Vegetable Stearate
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
This product contains NO yeast, wheat gluten, soy protein, milk/dairy, corn, sodium, sugar, starch, artificial coloring, preservatives or flavoring.
Suggested/Recommended/Usage/Directions
Suggested Usage: As a dietary supplement, adults take 1 capsule daily or as directed by your healthcare professional.
Precautions
KEEP OUT OF REACH OF CHILDREN.
Tamper resistant package, do not use if outer seal is missing.
Storage
For optimal storage conditions, store in a cool, dry place. (59(0)-77(0)F/15(0)-25(0)C) (35-65% relative humidity)
General
Formula #7488
FDA Statement of Identity
A Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Branched Chain Amino Acids by Douglas Laboratories label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Branched Chain Amino Acids by Douglas Laboratories
These are the 4 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container100 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
L-Leucine
L-Isoleucine
L-Valine
L-Threonine
Interacts with3 drugs
Threonine is an essential amino acid your body needs but cannot make, so you must get it from food or supplements. Most people get plenty from a norma...
L-Threonine monograph & interactionsOther (inactive) ingredients: Cellulose, Gelatin, Vegetable Stearate. These complete the product’s ingredient list but are not active constituents.
Branched Chain Amino Acids by Douglas Laboratories Drug Interactions
HelloPharmacist Interaction Report
Branched Chain Amino Acids by Douglas Laboratories contains one ingredient we have data for: L-Threonine.
Threonine may decrease the effects of NMDA antagonists (a class of medications used for certain neurological conditions). This happens because threonine raises glycine levels in the brain, and glycine enhances how NMDA receptors work — essentially countering what these drugs are meant to do.
Read the full breakdown — every affected drug type, severity by severity
The other three active ingredients — L-Leucine, L-Isoleucine, and L-Valine — we could not check; we hold no interaction data for them. Altogether, these interactions span 3 individual medications.
If you take any NMDA antagonist or other prescription medication, use the search tool below to check your exact drugs before you start. Your pharmacist can also walk you through whether this product and your medications will work safely together.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Branched Chain Amino Acids?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Branched Chain Amino Acids interact with 3 drugs. Click any drug to see the details.
1 of the 4 ingredients in Branched Chain Amino Acids interact with drugs. Each result below shows which ingredient is responsible. L-Threonine
MemantineEbixa
How Memantine interacts with Branched Chain Amino Acids — through 1 ingredient. Tap an ingredient for the detail:
L-threonineNmda Antagonists Major
Interaction Summary
Theoretically, threonine might decrease the effects of NMDA antagonists.
Read the full L-threonine + Memantine interactionMemantine HydrochlorideNamenda
How Memantine Hydrochloride interacts with Branched Chain Amino Acids — through 1 ingredient. Tap an ingredient for the detail:
L-threonineNmda Antagonists Major
Interaction Summary
Theoretically, threonine might decrease the effects of NMDA antagonists.
Read the full L-threonine + Memantine Hydrochloride interactionMemantine, DonepezilNamzaric
How Memantine, Donepezil interacts with Branched Chain Amino Acids — through 1 ingredient. Tap an ingredient for the detail:
L-threonineNmda Antagonists Major
Interaction Summary
Theoretically, threonine might decrease the effects of NMDA antagonists.
Read the full L-threonine + Memantine, Donepezil interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Branched Chain Amino Acids with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
L-Threonine
Nmda Antagonists
Theoretically, threonine might decrease the effects of NMDA antagonists.
Threonine increases central nervous system (CNS) glycine levels. Glycine seems to bind a site on NMDA receptors and enhance the activity of the receptors.
Brand information
Manufacturer and brand details for Branched Chain Amino Acids, from the product label.
Douglas Laboratories
See all Douglas Laboratories products- Name
- Douglas Laboratories
- Street Address
- 600 Boyce Road
- City
- Pittsburgh
- State
- PA
- ZipCode
- 15205
- Phone Number
- 1.800.245.4440
- Web Address
- www.douglaslabs.com
Branched Chain Amino Acids by Douglas Laboratories: Common Questions
Does Branched Chain Amino Acids by Douglas Laboratories interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What are branched chain amino acids, and what do they do?
Does threonine help with ALS or multiple sclerosis?
What side effects has threonine caused?
Can I take this if I'm pregnant or breastfeeding?
What's in the capsule besides the amino acids?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Branched Chain Amino Acids is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Branched Chain Amino Acids’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Branched Chain Amino Acids's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 4 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Threonine 4 references
- Tandan R, Bromberg MB, Forshew D, et al. A controlled trial of amino acid therapy in amyotrophic lateral sclerosis: I. Clinical, functional, and maximum isometric torque data. Neurology 1996;47:1220-6. PubMed
- Lee A, Patterson V. A double blind study of L-threonine in patients with spinal spasticity. Acta Neurol Scand 1993;88:334-8. PubMed
- Blin O, Pouget J, Aubrespy G, et al. A double-blind placebo controlled trial of L-threonine in amyotrophic lateral sclerosis. J Neurol 1992;239:79-81.
- Roufs JB. L-threonine as a symptomatic treatment for amyotrophic lateral sclerosis (ALS). Med Hypotheses 1991;34:20-3. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC