Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Brocco Immune Ingredients & Drug Interactions

by Protocol For Life Balance

Brocco Immune label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Brocco Immune against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Brocco Immune is a dietary supplement by Protocol For Life Balance with 1 active ingredient. Its ingredients are commonly taken for general nutrition and antioxidant support, heart and digestive health, detoxification support.Based on those ingredients, 187 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are sgs(TM)-100. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Brocco Immune by Protocol For Life Balance

Ask about any prescription or over-the-counter medication and we check it for interactions with Brocco Immune by Protocol For Life Balance — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Brocco Immune by Protocol For Life Balance

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Brocco Immune contains one active ingredient: SGS(TM)-100, a broccoli extract. This concentrated form is designed to deliver the plant's bioactive compounds in capsule form.

The product also contains inactive ingredients — cellulose, magnesium stearate, and silica — which are standard capsule fillers and binders.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: cellular integrity and detoxification support.
  • We looked for evidence on: Colorectal cancer, Gastric cancer, Breast cancer, Prostate cancer, Bladder cancer, cellular protection — and 1 related terms.
  • The strongest evidence on file: Broccoli is rated "Possibly Effective" for Colorectal cancer (Natural Medicines).
  • Also on file: Broccoli is rated "Insufficient Reliable Evidence To Rate" for Bladder cancer, Breast cancer, Gastric cancer, Prostate cancer.

The evidence for broccoli in cancer prevention is mixed. For colorectal cancer, broccoli is rated possibly effective — the research suggests a potential benefit, but more study is needed to be certain.

For bladder, breast, and gastric cancers, as well as fibromyalgia, the evidence we hold is insufficient to rate whether it works. If you're considering this product for a specific health condition, talk it over with your doctor about what the current science actually supports.

The evidence, ingredient by ingredient Broccoli

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Broccoli as a food is well tolerated and safe for most people in normal amounts. However, concentrated broccoli supplements like this one are less studied, and the safety data we hold advises caution — the concentrated extracts haven't been as thoroughly tested as the food itself.

Some people have reported loose stools, diarrhea, stomach pain, and cramping after taking broccoli seed and sprout extracts, especially at higher doses. Pregnancy and lactation are rated likely safe, though the concentrated supplement form is less established than eating broccoli as food.

Side effects, ingredient by ingredient Broccoli

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Broccoli.
  • The most serious interaction on file is rated Moderate.
  • For scale: 187 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Brocco Immune, check with your doctor or pharmacist if you take any drugs broken down by CYP2A6 or CYP1A2 liver enzymes — these include medications for heart rhythm, blood pressure, cancer, and certain mental health conditions. The broccoli extract could lower how well those drugs work by speeding up how your body clears them.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This is a single-ingredient broccoli extract meant to support immune function, though the evidence for that specific claim isn't in the data we hold. It's generally well tolerated, but because it can speed up how your liver processes certain medications — potentially making them less effective — you'll want to check your exact prescriptions before starting.

If you're pregnant, breastfeeding, or have liver or kidney issues, talk with your doctor or pharmacist first to make sure it's right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2012.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Brocco Immune, straight from the product label.

Brand Protocol For Life Balance
Barcode (UPC) 707359130630
Net contents 60 Vcap(s)(R)
Market status On market
Date entered into DSLD Jul 25, 2012
DSLD ID 10554
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Brocco Immune by Protocol For Life Balance, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Vegetarian Capsule(s)
Maximum serving Sizes:
1 Vegetarian Capsule(s)
UPC/BARCODE
707359130630
IngredientAmount% DV
sgs(TM)-100300 mg--

Other ingredients: Cellulose, Cellulose, Magnesium Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

- Chemoprotective Compound - Detoxification - Supports Cellular Integrity 10% of profits donated for health research

Made in the U.S.A.

Please Recycle.

Broccoli and Broccoli Seeds are important sources of chemoprotective sulfur compounds, such as Glucoraphanin, that support the body's natural detoxification mechanisms. sgs(TM)-100 (Sulforaphane Glucosinolate) is a potent activator of the body's immune defense system through its effect on Phase 2 enzymes.

Peel Here for more information

It is widely recognized that broccoli and broccoli seeds can offer multiple health properties including vitamin C, beta-carotene, and fiber. Broccoli is also rich in phytochemicals, particularly glucoraphanin. Glucoraphanin is also found in other cruciferous vegetables, such as kale, turnip greens, cabbage, cauliflower, and Brussels sprouts. Cruciferous vegetables have long been associated with antioxidant and cellular protection. When broccoli and broccoli sprouts are consumed, glucoraphanin is converted to sulforaphane. It is quickly absorbed and metabolized, and finally excreted in the urine. In this process, it produces the formation of a variety of detoxifying and antioxidant peptides and proteins. Extensive scientific studies have demonstrated that sulforaphane is a potent inducer of phase 2 detoxifying enzymes. In addition, Sulforaphane is also able to boost the level of thioredoxin, an enzyme that protects retinal cells of the eye against various types of oxidative attack. For more information on sgs(TM), please visit www.yoursgsmed.com.

Guaranteed Quality This is an FDA-regulated dietary supplement that is produced in an FDA- and third party-inspected facility. We are certified for producing dietary supplements and USDA Organic products using Good Manufacturing Practices (GMP). All ingredients are quality tested to meet or exceed specifications. Our quality team goes above and beyond standard quality control to ensure the safety and efficacy of this supplement. We utilize advanced analytical and microbiological testing methods, with capabilities that are state-of-the-art and exceed basic lab requirements.

FDA Statement of Identity

A Dietary Supplement

Formulation

Vegetarian Formula

Contains no sugar, salt, starch, yeast, wheat, gluten, corn, soy, milk, egg, shellfish or preservatives.

Vegetarian/Vegan Product.

Seals/Symbols

GMP

Brand IP Statement(s)

sgs(TM) is produced under US patents 5,725,895; 5,968,505; 5,968,567; 6,177,122; 6,242,018; 6,521,818 and other US and international patents licensed from Brassica Protection Products LLC. Process patents pending to C S Health. sgs(TM)-100 is a trademark of C S Health. Vcaps(R) is a registered trademark of Capsugel.

Storage

Store in a cool, dry place.

General

CODE P3063 V2

Suggested/Recommended/Usage/Directions

SUGGESTED USAGE: As a dietary supplement, take 1 Vcap(R) daily, preferably with food.

Formula

Brocco Immune(TM) contains sgs(TM)-100 Broccoli Concentrate from seed.

Brocco Immune(TM) contains broccoli concentrate from broccoli seeds.

This product contains an Ageless(R) anti-oxygen packet to enhance protection during storage.

FDA Disclaimer Statement

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

Precautions

Do Not Eat Freshness Packet. Keep in Bottle.

Cautions and Interactions There are no known drug interactions.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Brocco Immune by Protocol For Life Balance label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Brocco Immune label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Brocco Immune by Protocol For Life Balance

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Vegetarian Capsule(s) Dosage formCapsule Amounts shown are per serving.

Sgs(TM)-100

Interacts with
187 drugs
300 mg per serving Form: Glucoraphanin

Broccoli is a nutritious cruciferous vegetable rich in fiber, vitamins, and plant compounds like sulforaphane that have drawn scientific interest for...

Sgs(TM)-100 monograph & interactions

Other (inactive) ingredients: Cellulose, Cellulose, Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Brocco Immune by Protocol For Life Balance Drug Interactions

Want to check YOUR meds against Brocco Immune?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
187Drugs
187 Moderate

Ingredients driving the most interactions

sgs(TM)-100 187

Individual Drug Interactions

The ingredients in Brocco Immune interact with 187 drugs. Click any drug to see the details.

1 of the 1 ingredient in Brocco Immune interact with drugs. Each result below shows which ingredient is responsible. sgs(TM)-100

Each ingredient & the kinds of drugs it affects

For each ingredient in Brocco Immune with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

sgs(TM)-1002 drug types · 187 drugs

Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP1A2.
Pharmacokinetic research in humans shows that eating 500 grams of fresh broccoli daily for 6-12 days can increase CYP1A2 activity by 10% to 200%. Induction of CYP1A2 activity by broccoli is attributed to its glucosinolate constituents.

Likelihood Possible Evidence B
Cytochrome P450 2A6 (Cyp2A6) Substrates

Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP2A6.
Pharmacokinetic research in humans shows that eating 500 grams of broccoli daily for 6 days increases CYP2A6 activity by 135% to 550%. Induction of CYP2A6 activity is attributed to its glucosinolate constituents.

Likelihood Possible Evidence B
sgs(TM)-100 full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Brocco Immune, from the product label.

Protocol For Life Balance

See all Protocol For Life Balance products
Name
NHG
Street Address
P.O. Box 2203
City
Sparks
State
NV
ZipCode
89431
Web Address
www.protocolforlife.com
Pharmacist Counseling Corner

Brocco Immune by Protocol For Life Balance: Common Questions

Does Brocco Immune by Protocol For Life Balance interact with any medications?
Yes. Based on its ingredients, Brocco Immune has a known interaction with 187 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Brocco Immune contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help my immune system?
The data we hold rates broccoli possibly effective for colorectal cancer prevention, but doesn't establish its effects on general immune function. If you're taking it for immunity specifically, talk with your doctor about whether the evidence supports its use for your situation.
Is concentrated broccoli extract as safe as eating broccoli at dinner?
Broccoli as food is safe for most people, but concentrated supplements are less studied. The safety data we hold advises caution with these extracts. Some people report loose stools, diarrhea, and stomach cramping, especially at higher doses.
Can I take this while I'm pregnant or breastfeeding?
Broccoli in this form is rated likely safe for pregnancy and lactation. That said, concentrated supplements are less established than food, so it's worth confirming with your doctor or pharmacist before you start.
What's SGS(TM)-100?
SGS(TM)-100 is a broccoli extract — the active ingredient in this product. It's designed to concentrate the compounds found in fresh broccoli into capsule form.
Why should I be careful about my other medications?
Broccoli extract can speed up your liver's ability to break down certain drugs, which may make those medications less effective. That's why it's important to check your exact prescriptions with your pharmacist or doctor before you start.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Brocco Immune is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Brocco Immune label
Go deeper

The Full Monographs Behind Brocco Immune’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Broccoli

Interacts with 187 drugs

Broccoli is a nutritious cruciferous vegetable rich in fiber, vitamins, and plant compounds like sulforaphane that have drawn scientific interest for health benefits. Eating broccoli as food...

Read the full Broccoli monograph →
Sources

Sources & How We Checked

Brocco Immune's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Broccoli 5 references
  1. Kristal AR, Lampe JW. Brassica vegetables and prostate cancer risk: a review of the epidemiological evidence. Nutr Cancer 2002;42:1-9. PubMed
  2. Chakrabarti A, Prais L, Foulds IS. Allergic contact dermatitis to broccoli. Br J Dermatol 2003;148:172-3. PubMed
  3. Hakooz, N. and Hamdan, I. Effects of dietary broccoli on human in vivo caffeine metabolism: a pilot study on a group of Jordanian volunteers. Curr Drug Metab 2007;8(1):9-15. PubMed
  4. Kall MA, Vang O, Clausen J. Effects of dietary broccoli on human drug metabolising activity. Cancer Lett. 1997;114(1-2):169-70. PubMed
  5. Bauman JE, Hsu CH, Centuori S, et al. Randomized Crossover Trial Evaluating Detoxification of Tobacco Carcinogens by Broccoli Seed and Sprout Extract in Current Smokers. Cancers (Basel). 2022;14(9):2129. Published 2022 Apr 24. PubMed

See these in context on the Broccoli monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team