B-12 Gold 2,400 mcg Ingredients & Drug Interactions
by NutriGold
What is this page for?
First and foremost: checking B-12 Gold 2,400 mcg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
B-12 Gold 2,400 mcg is a dietary supplement by NutriGold with 2 active ingredients. Its ingredients are commonly taken for treating or preventing b12 deficiency, pernicious anemia, low energy and fatigue.Based on those ingredients, 1,125 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Vitamin B12. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against B-12 Gold 2,400 mcg by NutriGold
Ask about any prescription or over-the-counter medication and we check it for interactions with B-12 Gold 2,400 mcg by NutriGold — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of B-12 Gold 2,400 mcg by NutriGold
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
B-12 Gold contains 13 active ingredients: Blueberry, Strawberry, Raspberry, Tomato, Kale, Parsley, Apple, Beet, Spinach, Green Cabbage, Vitamin B12, Broccoli, and organic Carrot. The star ingredient is Vitamin B12 at 2,400 micrograms — a dose well above the daily recommendation and useful for people with B12 deficiency or those taking metformin (which lowers B12).
The rest are fruit, vegetable, and herb extracts. The product also contains one inactive ingredient: a vegan capsule.
Does it work?
Leans against
Vitamin B12 is effective for treating B12 deficiency and managing related conditions. The evidence for the other 12 ingredients is much weaker.
Beet shows possibly effective evidence for athletic performance and exercise soreness; Broccoli is possibly effective for colorectal cancer; Carrot is possibly effective for vitamin A deficiency. For most other uses in this product — cardiovascular health, blood sugar control, cognitive function, cancer prevention — the evidence is insufficient to rate.
Several ingredients (like Blueberry, Apple, and Spinach) are marked possibly ineffective for specific conditions (hypertension, diarrhea, COPD). In short, you're buying this primarily for the B12; the vegetable blend is a nutritious bonus without proven therapeutic benefit.
How safe is it?
Well-documented data
Most ingredients are generally well tolerated as food. Vitamin B12 is very safe with no upper limit — your body excretes excess in urine.
However, some cautions apply. Freeze-dried Blueberry and Strawberry can cause gastrointestinal upset (nausea, diarrhea, constipation) in a meaningful number of people — one trial saw 26% of participants on freeze-dried blueberries drop out in week one due to GI complaints.
Parsley in large amounts carries serious rare risks (hemolytic anemia, thrombocytopenia) and is likely unsafe in pregnancy. Apple seeds contain cyanide and should not be consumed in quantity.
Beet can cause red or black stools (harmless) but theoretically kidney damage in very large doses. Carrot in excess has caused tooth decay in infants.
For pregnancy and breastfeeding, most ingredients are rated likely safe at normal food amounts, but concentrated supplement forms lack safety data — discuss with your provider before use during these periods.
Meds to double-check
Major interaction found
Before starting B-12 Gold, check whether you take blood thinners (anticoagulants) or antiplatelets like warfarin, aspirin, or clopidogrel — Strawberry and Parsley may increase bleeding risk. Check antihypertensive (blood pressure) and antidiabetes drugs, as multiple ingredients theoretically affect blood glucose and BP control.
Check any drugs metabolized by liver enzymes (CYP1A2, CYP2A6, CYP3A4), especially those listed for Cabbage, Beet, and Broccoli — enzyme induction could reduce drug levels. Check blood thinners again for Spinach and Cabbage's vitamin K content, which interferes with warfarin.
Check if you take Metformin — Vitamin B12 works with it, but Metformin can lower your B12. Ask your pharmacist to run your exact medications through our interaction checker on this page.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with graded evidence leaning against its stated purpose. Major medication interactions have been identified, and safety information is well characterized.
B-12 Gold is useful if you need B12 supplementation — the dose is solid and well-tolerated. The vegetable blend adds nutrition but no proven therapeutic benefit.
The real concern is its interactions with blood thinners, blood pressure meds, diabetes drugs, and liver-metabolized medications — if you take any prescription, check your list with our tool before starting. Avoid this product if you're pregnant and taking parsley concerns you, and know that some people experience GI upset from the freeze-dried fruit ingredients.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 12 of 13 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2022.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about B-12 Gold 2,400 mcg, straight from the product label.
| Brand | NutriGold |
|---|---|
| Barcode (UPC) | 859447002791 |
| Net contents | 60 Vegan Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Oct 24, 2022 |
| DSLD ID | 275769 |
| Product type | Botanical With Nutrients |
| Supplement form | Capsule |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for B-12 Gold 2,400 mcg by NutriGold, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Blueberry | 0 NP | -- |
| Strawberry | 0 NP | -- |
| Raspberry | 0 NP | -- |
| Tomato | 0 NP | -- |
| Kale | 0 NP | -- |
| Parsley | 0 NP | -- |
| Apple | 0 NP | -- |
| Beet | 0 NP | -- |
| Spinach | 0 NP | -- |
| Green Cabbage | 0 NP | -- |
| Vitamin B12 | 2400 mcg | 100000% |
| Organic Food Blend | 400 mg | -- |
| Broccoli | 0 NP | -- |
| organic Carrot | 0 NP | -- |
Other ingredients: Vegan capsule
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
Non-GMO verified, biologically-active B-12 complex formulated with organic fruit & veggie blend.
Methyl + Adenosyl
Ko Kosher (Kosher Service)
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Formulation
Health benefits: Supports cellular energy, cognitive health, and overall emotional wellness.
Verified free of corn, egg, gluten, milk, peanut, shellfish, and soy allergens by an independent lab. Manufactured without magnesium stearate, stearic acid, silicon dioxide, or chemical preservatives.
The B-12 in this product is sensitive to degradation.
Gluten-free Soy-free
Certified Vegan Vegan.org
Non-GMO verified, biologically-active B-12 complex formulated with organic fruit & veggie blend.
Highly bioactive complex
Precautions
Caution: Please consult a healthcare professional before taking this supplement if you are pregnant, breastfeeding, taking any medications, or planning a medical procedure.
Keep out of reach of children.
Storage
Store in original container away from moisture and direct sunlight.
Suggested/Recommended/Usage/Directions
Once opened, please consume product within 90 days.
Suggested use: As a dietary supplement, adults take 1 capsule daily, or as directed by a healthcare professional.
General Statements
To learn more about this product, scan QR code or visit nutrigold.com/item/279
Seals/Symbols
Certified Vegan Vegan.org Non GMO Project Verified nongmoproject.org Ko Kosher (Kosher Service)
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
B-12 Gold 2,400 mcg by NutriGold label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in B-12 Gold 2,400 mcg by NutriGold
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Vitamin B12
Interacts with20 drugs
Vitamin B12 (cobalamin) is an essential nutrient your body needs to make red blood cells, keep nerves healthy, and support DNA. Supplements are very h...
Vitamin B12 monograph & interactionsOrganic Food Blend
No knowninteractions
Organic food is grown and processed without most synthetic pesticides, fertilizers, antibiotics, or genetic engineering. Choosing organic can lower yo...
Organic Food Blend monograph & interactions- › Blueberry
- › Strawberry
- › Raspberry
- › Tomato
- › Kale
- › Parsley
- › Apple
- › Beet
- › Spinach
- › Green Cabbage
- › Broccoli
- › Organic Carrot
Other (inactive) ingredients: Vegan capsule. These complete the product’s ingredient list but are not active constituents.
B-12 Gold 2,400 mcg by NutriGold Drug Interactions
HelloPharmacist Interaction Report
B-12 Gold 2,400 mcg by NutriGold contains 13 ingredients, several of which interact with medications.
The most serious interaction comes from Apple, which significantly decreases absorption and blood levels of organic anion-transporting polypeptide substrates (OATP) — a Major severity finding. This means drugs like fexofenadine, atenolol, and aliskiren become less effective when taken with this product.
Read the full breakdown — every affected drug type, severity by severity
Multiple ingredients carry Moderate-severity interactions with blood thinners and blood pressure medications. Strawberry and Parsley both may increase bleeding risk with anticoagulants or antiplatelets (aspirin, warfarin, clopidogrel).
Parsley also interacts with antidiabetes drugs, diuretics, and warfarin specifically through its vitamin K content. Spinach contains vitamin K as well, which can interfere with warfarin.
Cabbage, Green Cabbage, Beet, and Broccoli all interact with drugs metabolized by liver enzymes (cytochrome P450), potentially reducing their effectiveness or raising their levels depending on the specific enzyme and drug. Apple juice also theoretically interferes with antihypertensive and antidiabetes drugs.
Blueberry carries Minor-severity interactions with antidiabetes drugs and certain pain relievers.
Additionally, we could not check Raspberry because interaction data is not on file for it. Altogether, these interactions span 1,110 individual medications.
Use the search tool on this page to check your exact prescriptions before starting this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against B-12 Gold 2,400 mcg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in B-12 Gold 2,400 mcg interact with 1,125 drugs. Click any drug to see the details.
1 of the 2 ingredients in B-12 Gold 2,400 mcg interact with drugs. Each result below shows which ingredient is responsible. Vitamin B12
AtorvastatinAtorvaliq
How Atorvastatin interacts with B-12 Gold 2,400 mcg — through 3 ingredients. Tap an ingredient for the detail:
AppleOrganic Anion-transporting Polypeptide Substrates (oatp) Major
Interaction Summary
Concomitant consumption of apple juice can significantly decrease oral absorption and blood levels of OATP substrates.
Read the full Apple + Atorvastatin interactionBeetCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet + Atorvastatin interactionGreen CabbageGlucuronidated Drugs Moderate
Interaction Summary
Theoretically, cabbage might increase clearance and decrease the effects of drugs metabolized through glucuronide conjugation.
Read the full Green Cabbage + Atorvastatin interactionAtorvastatin CalciumLipitor
How Atorvastatin Calcium interacts with B-12 Gold 2,400 mcg — through 3 ingredients. Tap an ingredient for the detail:
AppleOrganic Anion-transporting Polypeptide Substrates (oatp) Major
Interaction Summary
Concomitant consumption of apple juice can significantly decrease oral absorption and blood levels of OATP substrates.
Read the full Apple + Atorvastatin Calcium interactionGreen CabbageGlucuronidated Drugs Moderate
Interaction Summary
Theoretically, cabbage might increase clearance and decrease the effects of drugs metabolized through glucuronide conjugation.
Read the full Green Cabbage + Atorvastatin Calcium interactionBeetCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet + Atorvastatin Calcium interactionBosentanTracleer
How Bosentan interacts with B-12 Gold 2,400 mcg — through 2 ingredients. Tap an ingredient for the detail:
AppleOrganic Anion-transporting Polypeptide Substrates (oatp), Antihypertensive Drugs Major
Interaction Summary
Concomitant consumption of apple juice can significantly decrease oral absorption and blood levels of OATP substrates.
Read the full Apple + Bosentan interactionBeetCytochrome P450 3a4 (cyp3a4) Substrates, Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet + Bosentan interactionBrincidofovirTembexa
How Brincidofovir interacts with B-12 Gold 2,400 mcg — through 1 ingredient. Tap an ingredient for the detail:
AppleOrganic Anion-transporting Polypeptide Substrates (oatp) Major
Interaction Summary
Concomitant consumption of apple juice can significantly decrease oral absorption and blood levels of OATP substrates.
Read the full Apple + Brincidofovir interactionCeliprololCelicard
How Celiprolol interacts with B-12 Gold 2,400 mcg — through 3 ingredients. Tap an ingredient for the detail:
AppleOrganic Anion-transporting Polypeptide Substrates (oatp), Antihypertensive Drugs Major
Interaction Summary
Concomitant consumption of apple juice can significantly decrease oral absorption and blood levels of OATP substrates.
Read the full Apple + Celiprolol interactionStrawberryP-glycoprotein Substrates Moderate
Interaction Summary
In vitro research suggests that strawberry extract can inhibit p-glycoprotein efflux.
Read the full Strawberry + Celiprolol interactionBeetAntihypertensive Drugs Minor
Interaction Summary
Beet and beetroot contain nitrates, which can cause vasodilation, potentially leading to lower blood pressure.
Read the full Beet + Celiprolol interactionCerivastatin SodiumBaycol
How Cerivastatin Sodium interacts with B-12 Gold 2,400 mcg — through 1 ingredient. Tap an ingredient for the detail:
AppleOrganic Anion-transporting Polypeptide Substrates (oatp) Major
Interaction Summary
Concomitant consumption of apple juice can significantly decrease oral absorption and blood levels of OATP substrates.
Read the full Apple + Cerivastatin Sodium interactionCinoxacinCinobac
How Cinoxacin interacts with B-12 Gold 2,400 mcg — through 1 ingredient. Tap an ingredient for the detail:
AppleOrganic Anion-transporting Polypeptide Substrates (oatp) Major
Interaction Summary
Concomitant consumption of apple juice can significantly decrease oral absorption and blood levels of OATP substrates.
Read the full Apple + Cinoxacin interactionCiprofloxacinCiloxan, Cipro, Cipro IV, Cipro XR, Ciprobay, Otiprio
How Ciprofloxacin interacts with B-12 Gold 2,400 mcg — through 1 ingredient. Tap an ingredient for the detail:
AppleOrganic Anion-transporting Polypeptide Substrates (oatp) Major
Interaction Summary
Concomitant consumption of apple juice can significantly decrease oral absorption and blood levels of OATP substrates.
Read the full Apple + Ciprofloxacin interactionCiprofloxacin, HydrocortisoneCipro HC Otic
How Ciprofloxacin, Hydrocortisone interacts with B-12 Gold 2,400 mcg — through 1 ingredient. Tap an ingredient for the detail:
AppleOrganic Anion-transporting Polypeptide Substrates (oatp) Major
Interaction Summary
Concomitant consumption of apple juice can significantly decrease oral absorption and blood levels of OATP substrates.
Read the full Apple + Ciprofloxacin, Hydrocortisone interactionClinafloxacinClinafloxacin
How Clinafloxacin interacts with B-12 Gold 2,400 mcg — through 1 ingredient. Tap an ingredient for the detail:
AppleOrganic Anion-transporting Polypeptide Substrates (oatp) Major
Interaction Summary
Concomitant consumption of apple juice can significantly decrease oral absorption and blood levels of OATP substrates.
Read the full Apple + Clinafloxacin interactionEnoxacinPenetrex
How Enoxacin interacts with B-12 Gold 2,400 mcg — through 1 ingredient. Tap an ingredient for the detail:
AppleOrganic Anion-transporting Polypeptide Substrates (oatp) Major
Interaction Summary
Concomitant consumption of apple juice can significantly decrease oral absorption and blood levels of OATP substrates.
Read the full Apple + Enoxacin interactionEtoposideEtopophos, VePesid, VP16
How Etoposide interacts with B-12 Gold 2,400 mcg — through 3 ingredients. Tap an ingredient for the detail:
AppleOrganic Anion-transporting Polypeptide Substrates (oatp) Major
Interaction Summary
Concomitant consumption of apple juice can significantly decrease oral absorption and blood levels of OATP substrates.
Read the full Apple + Etoposide interactionBeetCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet + Etoposide interactionStrawberryP-glycoprotein Substrates Moderate
Interaction Summary
In vitro research suggests that strawberry extract can inhibit p-glycoprotein efflux.
Read the full Strawberry + Etoposide interactionEzetimibe, AtorvastatinLiptruzet
How Ezetimibe, Atorvastatin interacts with B-12 Gold 2,400 mcg — through 3 ingredients. Tap an ingredient for the detail:
AppleOrganic Anion-transporting Polypeptide Substrates (oatp) Major
Interaction Summary
Concomitant consumption of apple juice can significantly decrease oral absorption and blood levels of OATP substrates.
Read the full Apple + Ezetimibe, Atorvastatin interactionGreen CabbageGlucuronidated Drugs Moderate
Interaction Summary
Theoretically, cabbage might increase clearance and decrease the effects of drugs metabolized through glucuronide conjugation.
Read the full Green Cabbage + Ezetimibe, Atorvastatin interactionBeetCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet + Ezetimibe, Atorvastatin interactionFexofenadineAllegra
How Fexofenadine interacts with B-12 Gold 2,400 mcg — through 3 ingredients. Tap an ingredient for the detail:
AppleOrganic Anion-transporting Polypeptide Substrates (oatp), Fexofenadine (allegra) Major
Interaction Summary
Concomitant consumption of apple juice can significantly decrease oral absorption and blood levels of OATP substrates.
Read the full Apple + Fexofenadine interactionStrawberryP-glycoprotein Substrates Moderate
Interaction Summary
In vitro research suggests that strawberry extract can inhibit p-glycoprotein efflux.
Read the full Strawberry + Fexofenadine interactionBeetCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet + Fexofenadine interactionFexofenadine, PseudoephedrineAllegra D
How Fexofenadine, Pseudoephedrine interacts with B-12 Gold 2,400 mcg — through 3 ingredients. Tap an ingredient for the detail:
AppleOrganic Anion-transporting Polypeptide Substrates (oatp), Fexofenadine (allegra) Major
Interaction Summary
Concomitant consumption of apple juice can significantly decrease oral absorption and blood levels of OATP substrates.
Read the full Apple + Fexofenadine, Pseudoephedrine interactionBeetCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet + Fexofenadine, Pseudoephedrine interactionStrawberryP-glycoprotein Substrates Moderate
Interaction Summary
In vitro research suggests that strawberry extract can inhibit p-glycoprotein efflux.
Read the full Strawberry + Fexofenadine, Pseudoephedrine interactionFluvastatinLescol, Lescol XL
How Fluvastatin interacts with B-12 Gold 2,400 mcg — through 1 ingredient. Tap an ingredient for the detail:
AppleOrganic Anion-transporting Polypeptide Substrates (oatp) Major
Interaction Summary
Concomitant consumption of apple juice can significantly decrease oral absorption and blood levels of OATP substrates.
Read the full Apple + Fluvastatin interactionGatifloxacinTequin, Tequin Injection
How Gatifloxacin interacts with B-12 Gold 2,400 mcg — through 1 ingredient. Tap an ingredient for the detail:
AppleOrganic Anion-transporting Polypeptide Substrates (oatp) Major
Interaction Summary
Concomitant consumption of apple juice can significantly decrease oral absorption and blood levels of OATP substrates.
Read the full Apple + Gatifloxacin interactionGemifloxacinFactive
How Gemifloxacin interacts with B-12 Gold 2,400 mcg — through 1 ingredient. Tap an ingredient for the detail:
AppleOrganic Anion-transporting Polypeptide Substrates (oatp) Major
Interaction Summary
Concomitant consumption of apple juice can significantly decrease oral absorption and blood levels of OATP substrates.
Read the full Apple + Gemifloxacin interactionGlyburideAlbert Glyburide, Diabeta, Glycron, Glynase, Glynase PresTab, Micronase +1 more
How Glyburide interacts with B-12 Gold 2,400 mcg — through 5 ingredients. Tap an ingredient for the detail:
AppleOrganic Anion-transporting Polypeptide Substrates (oatp), Antidiabetes Drugs Major
Interaction Summary
Concomitant consumption of apple juice can significantly decrease oral absorption and blood levels of OATP substrates.
Read the full Apple + Glyburide interactionSpinachAntidiabetes Drugs Moderate
Interaction Summary
There are claims that spinach leaves have hypoglycemic effects.
Read the full Spinach + Glyburide interactionParsleyAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, parsley might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Parsley + Glyburide interactionGreen CabbageAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, cabbage might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Green Cabbage + Glyburide interactionBlueberryAntidiabetes Drugs Minor
Interaction Summary
Theoretically, blueberries or blueberry leaf extracts might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Blueberry + Glyburide interactionGlyburide, MetforminGlucovance
How Glyburide, Metformin interacts with B-12 Gold 2,400 mcg — through 6 ingredients. Tap an ingredient for the detail:
AppleOrganic Anion-transporting Polypeptide Substrates (oatp), Antidiabetes Drugs Major
Interaction Summary
Concomitant consumption of apple juice can significantly decrease oral absorption and blood levels of OATP substrates.
Read the full Apple + Glyburide, Metformin interactionGreen CabbageAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, cabbage might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Green Cabbage + Glyburide, Metformin interactionSpinachAntidiabetes Drugs Moderate
Interaction Summary
There are claims that spinach leaves have hypoglycemic effects.
Read the full Spinach + Glyburide, Metformin interactionParsleyAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, parsley might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Parsley + Glyburide, Metformin interactionBlueberryAntidiabetes Drugs Minor
Interaction Summary
Theoretically, blueberries or blueberry leaf extracts might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Blueberry + Glyburide, Metformin interactionVitamin B12Metformin (glucophage) Minor
Interaction Summary
Metformin, a common medication used to manage type 2 diabetes, has been associated with lower vitamin B12 levels in some individuals.
Read the full Vitamin B12 + Glyburide, Metformin interactionGrepafloxacinRaxar
How Grepafloxacin interacts with B-12 Gold 2,400 mcg — through 5 ingredients. Tap an ingredient for the detail:
AppleOrganic Anion-transporting Polypeptide Substrates (oatp) Major
Interaction Summary
Concomitant consumption of apple juice can significantly decrease oral absorption and blood levels of OATP substrates.
Read the full Apple + Grepafloxacin interactionParsleyCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, parsley might increase serum levels of CYP1A2 substrates.
Read the full Parsley + Grepafloxacin interactionGreen CabbageCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, cabbage might decrease levels of drugs metabolized by CYP1A2.
Read the full Green Cabbage + Grepafloxacin interactionBroccoliCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP1A2.
Read the full Broccoli + Grepafloxacin interactionBeetCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, beet might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Beet + Grepafloxacin interactionIrinotecanCamptosar, Onivyde
How Irinotecan interacts with B-12 Gold 2,400 mcg — through 3 ingredients. Tap an ingredient for the detail:
AppleOrganic Anion-transporting Polypeptide Substrates (oatp) Major
Interaction Summary
Concomitant consumption of apple juice can significantly decrease oral absorption and blood levels of OATP substrates.
Read the full Apple + Irinotecan interactionGreen CabbageGlucuronidated Drugs Moderate
Interaction Summary
Theoretically, cabbage might increase clearance and decrease the effects of drugs metabolized through glucuronide conjugation.
Read the full Green Cabbage + Irinotecan interactionBeetCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet + Irinotecan interactionIrinotecan Hydrochloride
How Irinotecan Hydrochloride interacts with B-12 Gold 2,400 mcg — through 3 ingredients. Tap an ingredient for the detail:
AppleOrganic Anion-transporting Polypeptide Substrates (oatp) Major
Interaction Summary
Concomitant consumption of apple juice can significantly decrease oral absorption and blood levels of OATP substrates.
Read the full Apple + Irinotecan Hydrochloride interactionGreen CabbageGlucuronidated Drugs Moderate
Interaction Summary
Theoretically, cabbage might increase clearance and decrease the effects of drugs metabolized through glucuronide conjugation.
Read the full Green Cabbage + Irinotecan Hydrochloride interactionBeetCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet + Irinotecan Hydrochloride interactionIsoniazid, Pyrazinamide, RifampinRifater
How Isoniazid, Pyrazinamide, Rifampin interacts with B-12 Gold 2,400 mcg — through 1 ingredient. Tap an ingredient for the detail:
AppleOrganic Anion-transporting Polypeptide Substrates (oatp) Major
Interaction Summary
Concomitant consumption of apple juice can significantly decrease oral absorption and blood levels of OATP substrates.
Read the full Apple + Isoniazid, Pyrazinamide, Rifampin interactionIsoniazid, RifampinRifamate
How Isoniazid, Rifampin interacts with B-12 Gold 2,400 mcg — through 1 ingredient. Tap an ingredient for the detail:
AppleOrganic Anion-transporting Polypeptide Substrates (oatp) Major
Interaction Summary
Concomitant consumption of apple juice can significantly decrease oral absorption and blood levels of OATP substrates.
Read the full Apple + Isoniazid, Rifampin interactionLevofloxacinLeva-pak, Levaquin, Levaquin Injection
How Levofloxacin interacts with B-12 Gold 2,400 mcg — through 1 ingredient. Tap an ingredient for the detail:
AppleOrganic Anion-transporting Polypeptide Substrates (oatp) Major
Interaction Summary
Concomitant consumption of apple juice can significantly decrease oral absorption and blood levels of OATP substrates.
Read the full Apple + Levofloxacin interactionLevofloxacin (ophthalmic)Levofloxacin
How Levofloxacin (ophthalmic) interacts with B-12 Gold 2,400 mcg — through 1 ingredient. Tap an ingredient for the detail:
AppleOrganic Anion-transporting Polypeptide Substrates (oatp) Major
Interaction Summary
Concomitant consumption of apple juice can significantly decrease oral absorption and blood levels of OATP substrates.
Read the full Apple + Levofloxacin (ophthalmic) interactionLomefloxacinMaxaquin
How Lomefloxacin interacts with B-12 Gold 2,400 mcg — through 1 ingredient. Tap an ingredient for the detail:
AppleOrganic Anion-transporting Polypeptide Substrates (oatp) Major
Interaction Summary
Concomitant consumption of apple juice can significantly decrease oral absorption and blood levels of OATP substrates.
Read the full Apple + Lomefloxacin interactionLovastatinAltocor, Mevacor
How Lovastatin interacts with B-12 Gold 2,400 mcg — through 3 ingredients. Tap an ingredient for the detail:
AppleOrganic Anion-transporting Polypeptide Substrates (oatp) Major
Interaction Summary
Concomitant consumption of apple juice can significantly decrease oral absorption and blood levels of OATP substrates.
Read the full Apple + Lovastatin interactionBeetCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet + Lovastatin interactionGreen CabbageGlucuronidated Drugs Moderate
Interaction Summary
Theoretically, cabbage might increase clearance and decrease the effects of drugs metabolized through glucuronide conjugation.
Read the full Green Cabbage + Lovastatin interactionMethotrexateOtrexup, Rasuvo, Reditrex, Rheumatrex
How Methotrexate interacts with B-12 Gold 2,400 mcg — through 1 ingredient. Tap an ingredient for the detail:
AppleOrganic Anion-transporting Polypeptide Substrates (oatp) Major
Interaction Summary
Concomitant consumption of apple juice can significantly decrease oral absorption and blood levels of OATP substrates.
Read the full Apple + Methotrexate interactionEach ingredient & the kinds of drugs it affects
For each ingredient in B-12 Gold 2,400 mcg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Vitamin B12
Metformin (Glucophage)
Metformin, a common medication used to manage type 2 diabetes, has been associated with lower vitamin B12 levels in some individuals. Prolonged use of metformin can interfere with the absorption of B12 in the digestive system, potentially leading to a deficiency in this essential vitamin.
Brand information
Manufacturer and brand details for B-12 Gold 2,400 mcg, from the product label.
NutriGold
- Name
- NutriGold Inc.
- City
- Orem
- State
- UT
- ZipCode
- 84057
- Phone Number
- (800) 476-3542
- Web Address
- www.nutrigold.com
B-12 Gold 2,400 mcg by NutriGold: Common Questions
Does B-12 Gold 2,400 mcg by NutriGold interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is B-12 Gold safe for me if I'm pregnant or breastfeeding?
Will the freeze-dried fruits in this product cause side effects?
Does B-12 Gold actually work, or is it just the vegetables?
Can I take this with my blood thinner (warfarin or aspirin)?
What if I'm taking metformin for diabetes?
Is there any ingredient in this product I should avoid?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if B-12 Gold 2,400 mcg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind B-12 Gold 2,400 mcg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Vitamin B12
Interacts with 20 drugsVitamin B12 (cobalamin) is an essential nutrient your body needs to make red blood cells, keep nerves healthy, and support DNA. Supplements are very helpful for people who are deficient — su...
Read the full Vitamin B12 monograph → Herb & supplement monographOrganic Food
Organic food is grown and processed without most synthetic pesticides, fertilizers, antibiotics, or genetic engineering. Choosing organic can lower your exposure to certain pesticide residue...
Read the full Organic Food monograph → Herb & supplement monographBlueberry
Interacts with 88 drugsBlueberries are a nutritious fruit rich in antioxidants called anthocyanins, and eating them as part of a balanced diet is healthy and safe for most people. Concentrated supplements are mark...
Read the full Blueberry monograph → Herb & supplement monographStrawberry
Interacts with 316 drugsStrawberry is a popular, nutrient-rich fruit that supplies vitamin C, fiber, and antioxidant plant compounds. Eating strawberries as part of a balanced diet is healthy for most people, but c...
Read the full Strawberry monograph → Herb & supplement monographTomato
Tomato is a common food rich in vitamins, potassium, and the antioxidant lycopene, and eating it as part of a balanced diet is healthy for most people. Concentrated tomato or lycopene supple...
Read the full Tomato monograph → Herb & supplement monographKale
Kale is a nutrient-dense leafy green vegetable that is rich in vitamins, minerals, fiber, and antioxidants. Eaten as a normal food it is very healthy for most people, but it is a whole food...
Read the full Kale monograph → Herb & supplement monographParsley
Interacts with 443 drugsParsley is a popular culinary herb that is safe to eat in normal food amounts and is a good source of vitamins K and C. It is traditionally used as a diuretic and for digestion, but solid hu...
Read the full Parsley monograph → Herb & supplement monographApple
Interacts with 300 drugsApples are a nutritious whole food that provides fiber, vitamins, and antioxidant plant compounds, and eating them regularly fits well into a healthy diet. While research suggests apples may...
Read the full Apple monograph → Herb & supplement monographBeet
Interacts with 861 drugsBeet, especially beetroot juice, is a nitrate-rich food that may modestly lower blood pressure and slightly improve exercise performance in some people. It is generally safe as a food, but s...
Read the full Beet monograph → Herb & supplement monographSpinach
Interacts with 88 drugsSpinach is a nutrient-dense leafy green that is a healthy part of a balanced diet, providing vitamins, minerals, fiber, and antioxidants. While it is very safe as a food, concentrated supple...
Read the full Spinach monograph → Herb & supplement monographCabbage
Interacts with 325 drugsCabbage is a nutritious, low-calorie vegetable that is safe to eat as food and is sometimes applied to the skin as a leaf wrap for breast engorgement or sore joints. Most medicinal claims ar...
Read the full Cabbage monograph → Herb & supplement monographBroccoli
Interacts with 187 drugsBroccoli is a nutritious cruciferous vegetable rich in fiber, vitamins, and plant compounds like sulforaphane that have drawn scientific interest for health benefits. Eating broccoli as food...
Read the full Broccoli monograph → Herb & supplement monographCarrot
Carrot is a common food vegetable that is a rich source of beta-carotene (which the body turns into vitamin A) and other nutrients. Eating carrots is safe and nutritious for most people, but...
Read the full Carrot monograph →Sources & How We Checked
B-12 Gold 2,400 mcg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 165 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Blueberry 7 references
- Cignarella A, Nastasi M, Cavalli E, Puglisi L. Novel lipid-lowering properties of Vaccinium myrtillus L. leaves, a traditional antidiabetic treatment, in several models of rat dyslipidaemia: a comparison with ciprofibrate. Thromb Res 1996;84:311-22. PubMed
- Wang SY, Lin HS. Antioxidant activity in fruits and leaves of blackberry, raspberry, and strawberry varies with cultivar and developmental stage. J Agric Food Chem 2000;48:140-6.. PubMed
- Martineau, L. C., Couture, A., Spoor, D., Benhaddou-Andaloussi, A., Harris, C., Meddah, B., Leduc, C., Burt, A., Vuong, T., Mai, Le P., Prentki, M., Bennett, S. A., Arnason, J. T., and Haddad, P. S. Anti-diabetic properties of the Canadian lowbush bluebe
- Vuong, T., Martineau, L. C., Ramassamy, C., Matar, C., and Haddad, P. S. Fermented Canadian lowbush blueberry juice stimulates glucose uptake and AMP-activated protein kinase in insulin-sensitive cultured muscle cells and adipocytes. Can J Physiol Pharma
- Hanley MJ, Masse G, Harmatz JS, Cancalon PF, Dolnikowski GG, Court MH, Greenblatt DJ. Effect of blueberry juice on clearance of buspirone and flurbiprofen in human volunteers. Br J Clin Pharmacol. 2013 Apr;75(4):1041-52. PubMed
- Basu A, Du M, Leyva MJ, et al. Blueberries decrease cardiovascular risk factors in obese men and women with metabolic syndrome. J Nutr 2010;140(9):1582-7. PubMed
- Basu A, Feng D, Planinic P, Ebersole JL, Lyons TJ, Alexander JM. Dietary blueberry and soluble fiber supplementation reduces risk of gestational diabetes in women with obesity in a randomized controlled trial. J Nutr 2021;151(5):1128-38. PubMed
Strawberry 18 references
- Grattan CE, Harman RR. Contact urticaria to strawberry. Contact Dermatitis 1985;13:191-2. . PubMed
- Dutta-Roy, A. K., Crosbie, L., and Gordon, M. J. Effects of tomato extract on human platelet aggregation in vitro. Platelets. 2001;12(4):218-227. PubMed
- Van Gelder, J., Deferme, S., Naesens, L., De Clercq, E., van den, Mooter G., Kinget, R., and Augustijns, P. Intestinal absorption enhancement of the ester prodrug tenofovir disoproxil fumarate through modulation of the biochemical barrier by defined este
- Deferme, S., Van Gelder, J., and Augustijns, P. Inhibitory effect of fruit extracts on P-glycoprotein-related efflux carriers: an in-vitro screening. J Pharm Pharmacol 2002;54(9):1213-1219.
- Naemura, A., Mitani, T., Ijiri, Y., Tamura, Y., Yamashita, T., Okimura, M., and Yamamoto, J. Anti-thrombotic effect of strawberries. Blood Coagul.Fibrinolysis 2005;16(7):501-509. PubMed
- Basu A, Betts NM, Nguyen A, Newman ED, Fu D, Lyons TJ. Freeze-dried strawberries lower serum cholesterol and lipid peroxidation in adults with abdominal adiposity and elevated serum lipids. J Nutr. 2014;144(6):830-7. PubMed
- Feresin RG, Johnson SA, Pourafshar S, et al. Impact of daily strawberry consumption on blood pressure and arterial stiffness in pre- and stage 1-hypertensive postmenopausal women: a randomized controlled trial. Food Funct. 2017;8(11):4139-4149. PubMed
- Moazen S, Amani R, Homayouni Rad A, Shahbazian H, Ahmadi K, Taha Jalali M. Effects of freeze-dried strawberry supplementation on metabolic biomarkers of atherosclerosis in subjects with type 2 diabetes: a randomized double-blind controlled trial. Ann Nutr PubMed
- Schell J, Scofield RH, Barrett JR, et al. Strawberries improve pain and inflammation in obese adults with radiographic evidence of knee osteoarthritis. Nutrients. 2017;9(9):949. PubMed
- Zunino SJ, Parelman MA, Freytag TL, et al. Effects of dietary strawberry powder on blood lipids and inflammatory markers in obese human subjects. Br J Nutr. 2012;108(5):900-9. PubMed
- Amani R, Moazen S, Shahbazian H, Ahmadi K, Jalali MT. Flavonoid-rich beverage effects on lipid profile and blood pressure in diabetic patients. World J Diabetes. 2014;5(6):962-8. PubMed
- Cabrera-Freitag P, Bermejo Becerro A, Abreu Ramírez MG, et al. Allergy to strawberry in children from the Mediterranean area: is it really allergy? J Investig Allergol Clin Immunol 2020;30(4):283-5. PubMed
- Hadi A, Askarpour M, Miraghajani M, Symonds ME, Sheikhi A, Ghaedi E. Effects of strawberry supplementation on cardiovascular risk factors: a comprehensive systematic review and meta-analysis of randomized controlled trials. Food Funct 2019;10(11):6987-98. PubMed
- Gao Q, Qin LQ, Arafa A, Eshak ES, Dong JY. Effects of strawberry intervention on cardiovascular risk factors: a meta-analysis of randomised controlled trials. Br J Nutr 2020;124(3):241-6. PubMed
- Basu A, Izuora K, Hooyman A, Scofield HR, Ebersole JL. Dietary Strawberries Improve Serum Metabolites of Cardiometabolic Risks in Adults with Features of the Metabolic Syndrome in a Randomized Controlled Crossover Trial. Int J Mol Sci 2023;24(3):2051. PubMed
- Huang L, Xiao D, Zhang X, et al. Strawberry Consumption, Cardiometabolic Risk Factors, and Vascular Function: A Randomized Controlled Trial in Adults with Moderate Hypercholesterolemia. J Nutr 2021;151(6):1517-1526. PubMed
- Basu A, Izuora K, Betts NM, et al. Dietary Strawberries Improve Cardiometabolic Risks in Adults with Obesity and Elevated Serum LDL Cholesterol in a Randomized Controlled Crossover Trial. Nutrients 2021;13(5):1421. PubMed
- Wilken MR, Lambert MNT, Christensen CB, Jeppesen PB. Effects of Anthocyanin-rich Berries on the Risk of Metabolic Syndrome: A Systematic Review and Meta-analysis. Rev Diabet Stud 2022;18(1):42-57. PubMed
Tomato 3 references
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Asero R, Mistrello G, Amato S. Airborne allergy to tomato proteins. Allergy. 2010;65(12):1626-7. PubMed
- Friedman M. Tomato Glycoalkaloids: Role in the Plant and in the Diet. J Agric Food Chem. 2002;50(21):5751-80. PubMed
Kale 2 references
Parsley 21 references
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Robbers JE, Tyler VE. Tyler's Herbs of Choice: The Therapeutic Use of Phytomedicinals. New York, NY: The Haworth Herbal Press, 1999.
- Foster S, Tyler VE. Tyler's Honest Herbal, 4th ed., Binghamton, NY: Haworth Herbal Press, 1999. DOI
- Eberhard P, Gall HM, Muller I, Moller R. Dramatic augmentation of a food allergy by acetylsalicylic acid. J Allergy Clin Immunol 2000;105:844 PubMed
- Tunali T, Yarat A, Yanardag R, et al. Effect of parsley (Petroselinum crispum) on the skin of STZ induced diabetic rats. Phytother Res 1999;13:138-41.. DOI
- Chuang CH, Doyle P, Wang JD, et al. Herbal medicines used during the first trimester and major congenital malformations: an analysis of data from a pregnancy cohort study. Drug Saf 2006;29:537-48. PubMed
- Ciganda C, and Laborde A. Herbal infusions used for induced abortion. J Toxicol.Clin Toxicol. 2003;41:235-239. PubMed
- Jakovljevic, V., Raskovic, A., Popovic, M., and Sabo, J. The effect of celery and parsley juices on pharmacodynamic activity of drugs involving cytochrome P450 in their metabolism. Eur.J Drug Metab Pharmacokinet. 2002;27(3):153-156. PubMed
- Kreydiyyeh, S. I. and Usta, J. Diuretic effect and mechanism of action of parsley. J Ethnopharmacol 2002;79(3):353-357. PubMed
- Yanardag, R., Bolkent, S., Tabakoglu-Oguz, A., and Ozsoy-Sacan, O. Effects of Petroselinum crispum extract on pancreatic B cells and blood glucose of streptozotocin-induced diabetic rats. Biol Pharm Bull. 2003;26(8):1206-1210. PubMed
- Bolkent, S., Yanardag, R., Ozsoy-Sacan, O., and Karabulut-Bulan, O. Effects of parsley (Petroselinum crispum) on the liver of diabetic rats: a morphological and biochemical study. Phytother.Res 2004;18(12):996-999.
- Ozsoy-Sacan, O., Yanardag, R., Orak, H., Ozgey, Y., Yarat, A., and Tunali, T. Effects of parsley (Petroselinum crispum) extract versus glibornuride on the liver of streptozotocin-induced diabetic rats. J Ethnopharmacol 3-8-2006;104(1-2):175-181. PubMed
- Peterson, S., Lampe, J. W., Bammler, T. K., Gross-Steinmeyer, K., and Eaton, D. L. Apiaceous vegetable constituents inhibit human cytochrome P-450 1A2 (hCYP1A2) activity and hCYP1A2-mediated mutagenicity of aflatoxin B1. Food Chem.Toxicol. 2006;44(9):147 PubMed
- Gadi, D., Bnouham, M., Aziz, M., Ziyyat, A., Legssyer, A., Legrand, C., Lafeve, F. F., and Mekhfi, H. Parsley extract inhibits in vitro and ex vivo platelet aggregation and prolongs bleeding time in rats. J Ethnopharmacol 8-17-2009;125(1):170-174. PubMed
- Arslan S, Ucar R, Caliskaner AZ. A Cases of Near-fatal Anaphylaxis: Parsley "Over-use" as an Herbal Remedy. Med Arch. 2014;68(6):426-7.
- Foti C, Cassano N, Mistrello G, Amato S, Romita P, Vena GA. Contact urticaria to raw arugula and parsley. Ann Allergy Asthma Immunol. 2011 May;106(5):447-8. PubMed
- Farzaei MH, Abbasabadi Z, Ardekani MR, Rahimi R, Farzaei F. Parsley: a review of ethnopharmacology, phytochemistry and biological activities. J Tradit Chin Med. 2013;33(6):815-26. PubMed
- Kurtaran M, Koc NS, Aksun MS, Yildirim T, Yilmaz SR, Erdem Y. Petroselinum crispum, a commonly consumed food, affects sirolimus level in a renal transplant recipient: a case report. Ther Adv Drug Saf 2021;12:20420986211009358.
Apple 16 references
- The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
- Bailey DG, Dresser GK, Munoz C, et al. Reduction of fexofenadine bioavailability by fruit juices. Clin Pharmacol Ther 2001;69:P21.
- Rodriguez J, Crespo JF, Lopez-Rubio A, et al. Clinical cross-reactivity among foods of the Rosaceae family. J Allergy Clin Immunol 2000;106:183-189. PubMed
- Greenblatt DJ. Analysis of drug interactions involving fruit beverages and organic anion-transporting polypeptides. J Clin Pharmacol 2009;49:1403-7. PubMed
- Bailey DG. Fruit juice inhibition of uptake transport: a new type of food-drug interaction. Br J Clin Pharmacol 2010;70:645-55. PubMed
- Kamath AV, Yao M, Zhang Y, Chong S. Effect of fruit juices on the oral bioavailability of fexofenadine in rats. J Pharm Sci 2005;94:233-9. PubMed
- Tapaninen T, Neuvonen PJ, Niemi M. Orange and apple juice greatly reduce the plasma concentrations of the OATP2B1 substrate aliskiren. Br J Clin Pharmacol 2011;71:718-26. PubMed
- Jeon H, Jang IJ, Lee S, et al. Apple juice greatly reduces systemic exposure to atenolol. Br J Clin Pharmacol 2012 May 11. doi: 10.1111/j.1365-2125.2012.04324.x. [Epub ahead of print]. PubMed
- Visvanathan, R., Chen, R., Horowitz, M., and Chapman, I. Blood pressure responses in healthy older people to 50 g carbohydrate drinks with differing glycaemic effects. Br J Nutr 2004;92(2):335-340. PubMed
- Asp, N. G., Agardh, C. D., Ahren, B., Dencker, I., Johansson, C. G., Lundquist, I., Nyman, M., Sartor, G., and Schersten, B. Dietary fibre in type II diabetes. Acta Med Scand Suppl 1981;656:47-50. PubMed
- Akamine Y, Miura M, Komori H, et al. Effects of one-time apple juice ingestion on the pharmacokinetics of fexofenadine enantiomers. Eur J Clin Pharmacol. 2014 Sep;70(9):1087-95. PubMed
- Luo J, Imai H, Ohyama T, et al. The Pharmacokinetic Exposure to Fexofenadine is Volume-Dependently Reduced in Healthy Subjects Following Oral Administration With Apple Juice. Clin Transl Sci. 2016 Aug;9(4):201-6. PubMed
- Tsiougkos N, Vovolis V. Repeated anaphylactic episodes to orange and apple. Eur Ann Allergy Clin Immunol. 2013 May;45(3):113-5.
- Rubido S, García-Caballero L, Abeleira MT, Limeres J, García M, Diz P. Effect of chewing an apple on dental plaque removal and on salivary bacterial viability. PLoS One. 2018;13(7):e0199812. PubMed
- Krishnasamy S, Lomer MCE, Marciani L, et al. Processing apples to puree or juice speeds gastric emptying and reduces postprandial intestinal volumes and satiety in healthy adults. J Nutr 2020;150(11):2890-9. PubMed
- Awan S, Abelleira A, Khehra L, Hieber R. Undetectable serum lithium concentrations after coadministration of liquid lithium citrate and apple juice: A case report. Ment Health Clin. 2021;11(1):27-30. PubMed
Beet 14 references
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Clifford T, Berntzen B, Davison GW, et al. Effects of beetroot juice on recovery of muscle function and performance between bouts of repeated sprint exercise. Nutrients 2016;8. pii: E506. PubMed
- Siervo M, Lara J, Ogbonmwan I, Mathers JC. Inorganic nitrate and beetroot juice supplementation reduces blood pressure in adults: a systematic review and meta-analysis. J Nutr 2013;143:818-26. PubMed
- Clifford T, Howatson G, West DJ, Stevenson EJ. Beetroot juice is more beneficial than sodium nitrate for attenuating muscle pain after strenuous eccentric-bias exercise. Appl Physiol Nutr Metab. 2017;42(11):1185-1191. PubMed
- Clifford T, Bell O, West DJ, Howatson G, Stevenson EJ. The effects of beetroot juice supplementation on indices of muscle damage following eccentric exercise. Eur J Appl Physiol. 2016;116(2):353-62. PubMed
- Wylie LJ, Kelly J, Bailey SJ, et al. Beetroot juice and exercise: pharmacodynamic and dose-response relationships. J Appl Physiol (1985). 2013;115(3):325-36. PubMed
- Garnacho-Castaño MV, Palau-Salvà G, Cuenca E, et al. Effects of a single dose of beetroot juice on cycling time trial performance at ventilatory thresholds intensity in male triathletes. J Int Soc Sports Nutr. 2018;15(1):49. PubMed
- Rasica L, Porcelli S, Marzorati M, et al. Ergogenic effects of beetroot juice supplementation during severe-intensity exercise in obese adolescents. Am J Physiol Regul Integr Comp Physiol. 2018;315(3):R453-R460. PubMed
- Henrohn D, Björkstrand K, Lundberg JO, et al. Effects of oral supplementation with nitrate-rich beetroot juice in patients with pulmonary arterial hypertension-results from BEET-PAH, an exploratory randomized, double-blind, placebo-controlled, crosso
- Serra-Payá N, Garnacho-Castaño MV, Sánchez-Nuño S, et al. The relationship between resistance exercise performance and ventilatory efficiency after beetroot juice intake in well-trained athletes. Nutrients 2021;13(4):1094. PubMed
- Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
- Hemmatinafar M, Zaremoayedi L, Koushkie Jahromi M, et al. Effect of Beetroot Juice Supplementation on Muscle Soreness and Performance Recovery after Exercise-Induced Muscle Damage in Female Volleyball Players. Nutrients 2023;15(17):3763. PubMed
- Lim SH, Bae S, Lee HS, Han HK, Choi CI. Effect of Betanin, the Major Pigment of Red Beetroot (Beta vulgaris L.), on the Activity of Recombinant Human Cytochrome P450 Enzymes. Pharmaceuticals (Basel) 2023;16(9):1224. PubMed
- Oscherwitz M, Tamayo RM, Heudebert A, Centor R. A Case of Pseudo-Hematochezia from Beet Supplement Ingestion. Am J Med 2023;136(9):e177-e178. PubMed
Spinach 6 references
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Karlson, B., Leijd, B., and Hellstrom, K. On the influence of vitamin K-rich vegetables and wine on the effectiveness of warfarin treatment. Acta Med Scand. 1986;220(4):347-350. PubMed
- Roller, E., Meller, S., Homey, B., Ruzicka, T., and Neumann, N. J. [Contact dermatitis caused by spinach, hedge mustard and chives]. Hautarzt 2003;54(4):374-375.
- Schuller, A., Morisset, M., Maadi, F., Kolopp Sarda, M. N., Fremont, S., Parisot, L., Kanny, G., and Moneret-Vautrin, D. A. Occupational asthma due to allergy to spinach powder in a pasta factory. Allergy 2005;60(3):408-409. PubMed
- Gustafsson, K., Asp, N. G., Hagander, B., and Nyman, M. Satiety effects of spinach in mixed meals: comparison with other vegetables. Int.J.Food Sci.Nutr. 1995;46(4):327-334. PubMed
- Schreiber, J., Muller, E., Becker, W. M., Zabel, P., Schlaak, M., and Amthor, M. [Spinach powder-induced exogenous allergic alveolitis]. Pneumologie 1998;52(1):61-65.
Cabbage 15 references
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Pantuck EJ, Pantuck CB, Anderson KE, et al. Effect of brussels sprouts and cabbage on drug conjugation. Clin Pharmacol Ther 1984;35:161-9. PubMed
- Roberts KL. A comparison of chilled cabbage leaves and chilled gelpaks in reducing breast engorgement. J Hum Lact 1995;11:17-20. PubMed
- Roberts KL, Reiter M, Schuster D. A comparison of chilled and room temperature cabbage leaves in treating breast engorgement. J Hum Lact 1995;11:191-4. PubMed
- Roberts KL, Reiter M, Schuster D. Effects of cabbage leaf extract on breast engorgement. J Hum Lact 1998;14:231-6. PubMed
- Nikodem VC, Danziger D, Gebka N, et al. Do cabbage leaves prevent breast engorgement? A randomized, controlled study. Birth 1993;20:61-4. PubMed
- Balk JL. Indole-3-carbinol for cancer prevention. Altern Med Alert 2000; 3:105-7.
- He YH, Friesen MD, Ruch RJ, Schut HA. Indole-3-carbinol as a chemopreventive agent in 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) carcinogenesis: inhibition of PhIP-DNA adduct formation, acceleration of PhIP metabolism, and induction of cytoch
- Platel, K. and Srinivasan, K. Plant foods in the management of diabetes mellitus: vegetables as potential hypoglycaemic agents. Nahrung 1997;41(2):68-74. PubMed
- Steinkellner, H., Rabot, S., Freywald, C., Nobis, E., Scharf, G., Chabicovsky, M., Knasmuller, S., and Kassie, F. Effects of cruciferous vegetables and their constituents on drug metabolizing enzymes involved in the bioactivation of DNA-reactive dietary c
- Dolle S, Hompes S, Lange L, Worm M. Cabbage allergy: a rare cause of food-induced anaphylaxis. Acta Derm Venereol 2013;93(4):485-6. PubMed
- Lauche R, Graf N, Cramer H, Al-Abtah J, Dobos G, Saha FJ. Efficacy of cabbage leaf wraps in the treatment of symptomatic osteoarthritis of the knee: a randomized controlled trial. Clin J Pain 2016;32(11):961-71. PubMed
- Lim AR, Song JA, Hur MH, Lee MK, Lee MS. Cabbage compression early breast care on breast engorgement in primiparous women after cesarean birth: a controlled trial. Int J Clin Exp Med 2015;8(11):21335-42.
- Milanesi N, Gola M. Irritant contact dermatitis caused by Savoy cabbage. Contact Dermatitis 2016;74(1):60-1. PubMed
- Saini P, Saini R. Cabbage leaves and breast engorgement. Indian J Public Health 2014;58(4):291-2. PubMed
Vitamin B12 30 references
- Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
- Hartman TJ, Woodson K, Stolzenberg-Solomon R, et al. Association of the B-vitamins pyridoxal 5'-phosphate (B6), B12, and folate with lung cancer risk in older men. Am J Epidemiol 2001;153:688-94.. DOI
- Jansen T, Romiti R, Kreuter A, Altmeyer P. Rosacea fulminans triggered by high-dose vitamins B6 and B12. J Eur Acad Dermatol Venereol 2001;15:484-5..
- Lange H, Suryapranata H, De Luca G, et al. Folate therapy and in-stent restenosis after coronary stenting. N Engl J Med 2004;350:2673-81. PubMed
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