Glucomannan Gold 700 mg Ingredients & Drug Interactions
by NutriGold
What is this page for?
First and foremost: checking Glucomannan Gold 700 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Glucomannan Gold 700 mg is a dietary supplement by NutriGold with 2 active ingredients. Its ingredients are commonly taken for constipation, diarrhea, high cholesterol.Based on those ingredients, 2,025 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Dietary Fiber, Konjac Glucomannan. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Glucomannan Gold 700 mg by NutriGold
Ask about any prescription or over-the-counter medication and we check it for interactions with Glucomannan Gold 700 mg by NutriGold — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Glucomannan Gold 700 mg by NutriGold
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This supplement contains one active ingredient: konjac glucomannan, a soluble fiber derived from the konjac plant. It works by absorbing water in your digestive tract and forming a thick, gel-like material that bulks up stool and slows digestion.
The capsule also contains plant cellulose as an inactive ingredient.
Does it work?
Strong evidence
Glucomannan is possibly effective for constipation, diabetes, and high cholesterol (hyperlipidemia) based on available evidence. For high blood pressure, the evidence isn't reliable enough to rate it either way.
Keep in mind that 'possibly effective' means the science supports it to some degree, but more research may be needed to know how well it works for your particular situation.
How safe is it?
Well-documented data
When taken with plenty of water, glucomannan is generally well tolerated. Most side effects are digestive—abdominal pain, bloating, constipation, diarrhea, gas, nausea, and vomiting—especially if you take more than 3 grams daily.
Rare but serious risks include choking or blockage of your food pipe or gut, mainly if you swallow it dry or without enough liquid. There isn't enough safety data to know whether glucomannan is safe in pregnancy, and little is known about its safety while breastfeeding.
Talk with your doctor or pharmacist before using it if you're pregnant or nursing.
Meds to double-check
Moderate interaction found
Before taking Glucomannan Gold 700 mg, check with your pharmacist or doctor about any oral medications you're on. Glucomannan may lower how much of your drug your body absorbs, which could make it less effective.
Take your medications at least 2 hours away from this supplement to reduce that risk.
The bottom line
Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Glucomannan works best if you have constipation, are managing blood sugar, or want to help lower cholesterol, and you have room in your routine to dose it carefully apart from your other medications. The main catch is that it can reduce how well your body absorbs drugs taken by mouth, so spacing matters.
If you take any oral medications—especially diabetes drugs, blood pressure pills, or thyroid medication—check with your pharmacist before you start, and always take it with plenty of water to avoid blockage.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 23, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Glucomannan Gold 700 mg, straight from the product label.
| Brand | NutriGold |
|---|---|
| Barcode (UPC) | 859447002562 |
| Net contents | 120 Vegan Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Apr 23, 2024 |
| DSLD ID | 309171 |
| Product type | Fiber And Other Nutrients |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Glucomannan Gold 700 mg by NutriGold, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Total Carbohydrates | 1 Gram(s) | 1% |
| Dietary Fiber | 1 Gram(s) | 4% |
| Konjac Glucomannan | 1400 mg | -- |
Other ingredients: Plant Cellulose
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
Non-GMO verified, Tru-ID certified, fiber dense konjac root from Japan, processed without chemical additives for exceptional purity.
Fiber-rich konjac root
Ko Kosher Service
Formulation
Non-GMO verified, Tru-ID certified, fiber dense konjac root from Japan, processed without chemical additives for exceptional purity.
Health benefits: Supports healthy weight and digestive, heart, glucose, and gut health.
Manufactured without magnesium stearate, stearic acid, silicon dioxide, or chemical preservatives.
TRU-ID Certified Japanese source
Certified Vegan vegan.org
Non GMO Project Verified nongmoproject.org
General Statements
To learn more about this product, scan QR code or visit nutrigold.com/item/256
FDA Statement of Identity
Dietary Supplement
Seals/Symbols
Certified Vegan vegan.org Certified Authentic TRU-ID Non GMO Project Verified nongmoproject.org Ko Kosher Service
Suggested/Recommended/Usage/Directions
Suggested use: As a dietary supplement, adults take one 1 to 2 capsules up to 3 times daily, preferably 30 minutes before meals with 12 oz. of water, or as directed by a healthcare professional.
Precautions
Caution: Please consult a healthcare professional before taking this supplement if you are pregnant, breastfeeding, or taking any medications.
Keep out of reach of children.
Storage
Store in original container away from moisture and direct sunlight.
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Glucomannan Gold 700 mg by NutriGold label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Glucomannan Gold 700 mg by NutriGold
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Dietary Fiber
Interacts with2,025 drugs
Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. I...
Dietary Fiber monograph & interactionsKonjac Glucomannan
Interacts with2,022 drugs
Glucomannan is a soluble fiber from the konjac root that swells into a gel in your stomach, which may help with mild weight loss, constipation, and mo...
Konjac Glucomannan monograph & interactionsOther (inactive) ingredients: Plant Cellulose. These complete the product’s ingredient list but are not active constituents.
Glucomannan Gold 700 mg by NutriGold Drug Interactions
HelloPharmacist Interaction Report
Glucomannan Gold 700 mg by NutriGold can interact with oral medications through its main ingredient, konjac glucomannan.
Because glucomannan is viscous and bulks up in your digestive tract, it may slow or reduce how well your body absorbs drugs taken by mouth. A small study in healthy volunteers showed that glucomannan taken with glyburide (a diabetes medication) lowered the drug's blood levels.
Read the full breakdown — every affected drug type, severity by severity
The concern spans a very broad category: essentially any oral medication could theoretically be affected. Altogether, these interactions span 2,023 individual medications.
This doesn't mean you'll have a problem with every drug you take, but it does mean the timing and spacing matter.
To be safe, take your medications at least 2 hours apart from this supplement—either take your drugs first and wait before adding glucomannan, or reverse the order. If you take any prescription or over-the-counter medication by mouth, run it through the search tool on this page or talk with your pharmacist before starting this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Glucomannan Gold 700 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Glucomannan Gold 700 mg interact with 2,025 drugs. Click any drug to see the details.
2 of the 2 ingredients in Glucomannan Gold 700 mg interact with drugs. Each result below shows which ingredient is responsible. Dietary Fiber Konjac Glucomannan
"phentolamineOraVerse, Rogitine, Ryzumvi
How "phentolamine interacts with Glucomannan Gold 700 mg — through 2 ingredients. Tap an ingredient for the detail:
Konjac GlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Konjac Glucomannan + "phentolamine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + "phentolamine interaction6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Glucomannan Gold 700 mg — through 2 ingredients. Tap an ingredient for the detail:
Konjac GlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Konjac Glucomannan + 6-mercaptopurine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + 6-mercaptopurine interactionAbacavirZiagen
How Abacavir interacts with Glucomannan Gold 700 mg — through 2 ingredients. Tap an ingredient for the detail:
Konjac GlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Konjac Glucomannan + Abacavir interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Abacavir interactionAbacavir Sulfate, Dolutegravir, LamivudineTriumeq
How Abacavir Sulfate, Dolutegravir, Lamivudine interacts with Glucomannan Gold 700 mg — through 2 ingredients. Tap an ingredient for the detail:
Konjac GlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Konjac Glucomannan + Abacavir Sulfate, Dolutegravir, Lamivudine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Abacavir Sulfate, Dolutegravir, Lamivudine interactionAbacavir, LamivudineEpzicom
How Abacavir, Lamivudine interacts with Glucomannan Gold 700 mg — through 2 ingredients. Tap an ingredient for the detail:
Konjac GlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Konjac Glucomannan + Abacavir, Lamivudine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Abacavir, Lamivudine interactionAbciximabReoPro
How Abciximab interacts with Glucomannan Gold 700 mg — through 2 ingredients. Tap an ingredient for the detail:
Konjac GlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Konjac Glucomannan + Abciximab interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Glucomannan Gold 700 mg — through 2 ingredients. Tap an ingredient for the detail:
Konjac GlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Konjac Glucomannan + Abemaciclib interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Glucomannan Gold 700 mg — through 2 ingredients. Tap an ingredient for the detail:
Konjac GlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Konjac Glucomannan + Abiraterone interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Glucomannan Gold 700 mg — through 2 ingredients. Tap an ingredient for the detail:
Konjac GlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Konjac Glucomannan + Abiraterone Acetate interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Glucomannan Gold 700 mg — through 2 ingredients. Tap an ingredient for the detail:
Konjac GlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Konjac Glucomannan + Abrocitinib interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Glucomannan Gold 700 mg — through 2 ingredients. Tap an ingredient for the detail:
Konjac GlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Konjac Glucomannan + Acalabrutinib interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acalabrutinib interactionAcamprosateCampral
How Acamprosate interacts with Glucomannan Gold 700 mg — through 2 ingredients. Tap an ingredient for the detail:
Konjac GlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Konjac Glucomannan + Acamprosate interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acamprosate interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Glucomannan Gold 700 mg — through 2 ingredients. Tap an ingredient for the detail:
Konjac GlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Konjac Glucomannan + Acarbose interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Glucomannan Gold 700 mg — through 2 ingredients. Tap an ingredient for the detail:
Konjac GlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Konjac Glucomannan + Acebutolol interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Glucomannan Gold 700 mg — through 2 ingredients. Tap an ingredient for the detail:
Konjac GlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Konjac Glucomannan + Acenocoumarol interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acenocoumarol interactionAcepromazineAtravet
How Acepromazine interacts with Glucomannan Gold 700 mg — through 2 ingredients. Tap an ingredient for the detail:
Konjac GlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Konjac Glucomannan + Acepromazine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acepromazine interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Glucomannan Gold 700 mg — through 2 ingredients. Tap an ingredient for the detail:
Konjac GlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Konjac Glucomannan + Acetaminophen interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Glucomannan Gold 700 mg — through 2 ingredients. Tap an ingredient for the detail:
Konjac GlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Konjac Glucomannan + Acetaminophen, Aspirin interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Glucomannan Gold 700 mg — through 2 ingredients. Tap an ingredient for the detail:
Konjac GlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Konjac Glucomannan + Acetaminophen, Aspirin, Caffeine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Glucomannan Gold 700 mg — through 2 ingredients. Tap an ingredient for the detail:
Konjac GlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Konjac Glucomannan + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Glucomannan Gold 700 mg — through 2 ingredients. Tap an ingredient for the detail:
Konjac GlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Konjac Glucomannan + Acetaminophen, Butalbital interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Glucomannan Gold 700 mg — through 2 ingredients. Tap an ingredient for the detail:
Konjac GlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Konjac Glucomannan + Acetaminophen, Butalbital, Caffeine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Glucomannan Gold 700 mg — through 2 ingredients. Tap an ingredient for the detail:
Konjac GlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Konjac Glucomannan + Acetaminophen, Butalbital, Caffeine, Codeine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Glucomannan Gold 700 mg — through 2 ingredients. Tap an ingredient for the detail:
Konjac GlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Konjac Glucomannan + Acetaminophen, Butalbital, Codeine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Glucomannan Gold 700 mg — through 2 ingredients. Tap an ingredient for the detail:
Konjac GlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Konjac Glucomannan + Acetaminophen, Butalbital, Codeine Phosphate interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Glucomannan Gold 700 mg — through 2 ingredients. Tap an ingredient for the detail:
Konjac GlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Konjac Glucomannan + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Glucomannan Gold 700 mg — through 2 ingredients. Tap an ingredient for the detail:
Konjac GlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Konjac Glucomannan + Acetaminophen, Caffeine, Codeine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Glucomannan Gold 700 mg — through 2 ingredients. Tap an ingredient for the detail:
Konjac GlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Konjac Glucomannan + Acetaminophen, Caffeine, Codeine, Salicylamide interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Glucomannan Gold 700 mg — through 2 ingredients. Tap an ingredient for the detail:
Konjac GlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Konjac Glucomannan + Acetaminophen, Caffeine, Dihydrocodeine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Glucomannan Gold 700 mg — through 2 ingredients. Tap an ingredient for the detail:
Konjac GlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Konjac Glucomannan + Acetaminophen, Caffeine, Isometheptene interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetaminophen, Caffeine, Isometheptene interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Glucomannan Gold 700 mg with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Dietary Fiber
Carbamazepine (Tegretol)
Theoretically, black psyllium might reduce the effects of carbamazepine and increase the risk for convulsions.
Theoretically, black psyllium might reduce carbamazepine absorption. A preliminary study using blond psyllium reported decreased carbamazepine bioavailability due to binding of the drug to psyllium, as well as reduction of available fluid in the gut for dissolution of the drug. This interaction may also occur with black psyllium.
Lithium
Theoretically, taking black psyllium at the same time as lithium might reduce lithium absorption.
The fiber in black psyllium might reduce lithium absorption and plasma levels. Some case reports describe a reduction in plasma lithium levels with concomitant administration of blond psyllium. This was reversed when psyllium was stopped. This interaction may also occur with black psyllium.
Metformin (Glucophage)
Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Animal research shows that concurrent consumption of blond psyllium with metformin slows and increases the absorption of metformin. This interaction may also occur with black psyllium. To avoid changes in absorption, take psyllium 30-60 minutes after metformin.
Olanzapine (Zyprexa)
Theoretically, taking black psyllium at the same time as olanzapine might reduce olanzapine absorption.
The fiber in black psyllium might decrease the absorption of olanzapine. A single case report describes a reduction in the effectiveness of olanzapine when it was concomitantly administered with an unspecified type of psyllium 3 grams orally twice daily. This effect was reversed when psyllium was stopped.
Digoxin (Lanoxin)
Theoretically, taking black psyllium at the same time as digoxin might reduce digoxin absorption and decrease digoxin levels.
Psyllium might bind digoxin in the gut. However, some clinical evidence suggests that psyllium does not impact digoxin absorption.
Ethinyl Estradiol
Theoretically, taking black psyllium at the same time as ethinyl estradiol might alter levels of estradiol.
Concurrent use of blond psyllium with ethinyl estradiol results in a slight increase in the extent of ethinyl estradiol absorption and a slower rate of absorption. This is unlikely to be clinically significant.
Oral Drugs
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Psyllium seems to have variable effects on drug absorption. To avoid changes in absorption, take psyllium 30-60 minutes after oral medications. Animal research shows that blond psyllium delays and increases the absorption of metformin and ethinyl estradiol. Case reports and animal research suggest that blond psyllium might reduce absorption of lithium, digoxin, olanzapine, and carbamazepine. Finally, some pharmacokinetic studies show that psyllium does not affect the absorption of levothyroxine or warfarin. Although many of these studies evaluated blond psyllium, the fiber content in black psyllium may have similar effects.
Konjac Glucomannan
Oral Drugs
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Due to its viscosity and bulking effects, there is concern that glucomannan can decrease the absorption of oral drugs. A small clinical study in healthy volunteers shows that taking glyburide 2.5 mg plus glucomannan 3.9 grams with breakfast reduces plasma levels of glyburide when compared with breakfast and glyburide alone. In addition, animal research demonstrates this effect on amoxicillin, but shows increased absorption of metronidazole. This mouse model also demonstrates that metronidazole elimination is prolonged, but amoxicillin elimination is enhanced by 38%; glucomannan may also affect the distribution of some drugs. To avoid changes in absorption, take glucomannan 30-60 minutes after taking oral drugs.
Brand information
Manufacturer and brand details for Glucomannan Gold 700 mg, from the product label.
NutriGold
- Name
- NutriGold Inc.
- City
- Orem
- State
- UT
- ZipCode
- 84057
- Phone Number
- 800-476-3542
- Web Address
- www.nutrigold.com
Glucomannan Gold 700 mg by NutriGold: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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The Full Monographs Behind Glucomannan Gold 700 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Black Psyllium
Interacts with 2,025 drugsBlack psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. It is best known and most studied for rel...
Read the full Black Psyllium monograph → Herb & supplement monographGlucomannan
Interacts with 2,022 drugsGlucomannan is a soluble fiber from the konjac root that swells into a gel in your stomach, which may help with mild weight loss, constipation, and modestly lowering cholesterol. It is gener...
Read the full Glucomannan monograph →Sources & How We Checked
Glucomannan Gold 700 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 33 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Black Psyllium 18 references
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Covington TR, et al. Handbook of Nonprescription Drugs. 11th ed. Washington, DC: American Pharmaceutical Association, 1996.
- Etman M. Effect of a bulk forming laxative on the bioavailablility of carbamazepine in man. Drug Dev Ind Pharm 1995;21:1901-6.
- Perlman BB. Interaction between lithium salts and ispaghula husk. Lancet 1990;335:416.
- Vaswani SK, Hamilton RG, Valentine MD, Adkinson NF. Psyllium laxative-induced anaphylaxis, asthma, and rhinitis. Allergy 1996;51:266-8. PubMed
- Lantner RR, Espiritu BR, Zumerchik P, Tobin MC. Anaphylaxis following ingestion of a psyllium-containing cereal. JAMA 1990;264:2534-6. DOI
- Kaplan MJ. Anaphylactic reaction to "Heartwise." N Engl J Med 1990;323:1072-3. DOI
- Nordstrom M, Melander A, Robertsson E, Steen B. Influence of wheat bran and of a bulk-forming ispaghula cathartic on the bioavailability of digoxin in geriatric in-patients. Drug Nutr Interact 1987;5:67-9..
- Robinson DS, Benjamin DM, McCormack JJ. Interaction of warfarin and nonsystemic gastrointestinal drugs. Clin Pharmacol Ther 1971;12:491-5. PubMed
- Garcia JJ, Fernandez N, Diez MJ, et al. Influence of two dietary fibers in the oral bioavailability and other pharmacokinetic parameters of ethinyloestradiol. Contraception 2000;62:253-7. PubMed
- Fernandez N, Lopez C, Díez R, et al. Drug interactions with the dietary fiber Plantago ovata husk. Expert Opin Drug Metab Toxicol 2012;8(11):1377-86.
- Semen plantaginis in: WHO Monographs on Selected Medicinal Plants, volume 1. World Health Organization, Geneva, 1999. Available at http://apps.who.int/medicinedocs/en/d/Js2200e/. Accessed November 26, 1026.
- Code of Federal Regulations, Title 21 (21CFR 101.17). Food labeling warning, notice, and safe handling statements. Available at www.ecfr.gov/cgi-bin/text-idx?SID=20f647d3b74161501f46564b915b4048&mc=true&node=se21.2.101_117&rgn=div8. Accessed December 3, 2
- Code of Federal Regulations, Title 21 (21CFR 201.319). Specific labeling requirements - water-soluble gums, hydrophilic gums, and hydrophilic mucilloids. Available at www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=201.319. Accessed Dece
- Diez R, Garcia JJ, Diez MJ, Sierra M, Sahagun AM, Fernandez N. Influence of Plantago ovata husk (dietary fiber) on the bioavailability and other pharmacokinetic parameters of metformin in diabetic rabbits. BMC Complement Altern Med. 2017 Jun 7;17(1):298. PubMed
- Chiu AC, Sherman SI. Effects of pharmacological fiber supplements on levothyroxine absorption. Thyroid. 1998;8(8):667-71. PubMed
- Merrick C, Madden CA, Capurso NA. A Case of Blunted Orally Disintegrating Olanzapine Effect Due to Coadministered Psyllium. J Clin Psychiatry 2021;82(2):20cr13633. PubMed
Glucomannan 15 references
- Henry DA, Mitchell AS, Aylward J, et al. Glucomannan and risk of oesophageal obstruction. Br Med J 1986;292:591-2. PubMed
- Shima K, Tanaka A, Ikegami H, et al. Effect of dietary fiber, glucomannan, on absorption of sulfonylurea in man. Horm Metab Res 1983;15:1-3. PubMed
- Villaverde, A. F., Benlloch, S., Berenguer, M., Miguel, Rayon J., Pina, R., and Berenguer, J. Acute hepatitis of cholestatic type possibly associated with the use of glucomannan (amorphophalus konjac). J Hepatol. 2004;41(6):1061-1062. PubMed
- Yoshida, M., Vanstone, C. A., Parsons, W. D., Zawistowski, J., and Jones, P. J. Effect of plant sterols and glucomannan on lipids in individuals with and without type II diabetes. Eur.J Clin Nutr. 2006;60(4):529-537. PubMed
- Wood, R. J., Fernandez, M. L., Sharman, M. J., Silvestre, R., Greene, C. M., Zern, T. L., Shrestha, S., Judelson, D. A., Gomez, A. L., Kraemer, W. J., and Volek, J. S. Effects of a carbohydrate-restricted diet with and without supplemental soluble fiber
- Vanderbeek, P. B., Fasano, C., O'Malley, G., and Hornstein, J. Esophageal obstruction from a hygroscopic pharmacobezoar containing glucomannan. Clin Toxicol.(Phila) 2007;45(1):80-82. PubMed
- Bernstein, J. A., Crandall, M. S., and Floyd, R. Respiratory sensitization of a food manufacturing worker to konjac glucomannan. J Asthma 2007;44(8):675-680. PubMed
- Shichijo, K., Kobayashi, Y., Fueki, R., Shimoyama, K., and Masaya, M. [2 cases of konjac bronchial asthma found outside the "konnyaku" producing district]. Arerugi 1969;18(2):97-100.
- Carabin IG, Lyon MR, Wood S, et al. Supplementation of the diet with the functional fiber PolyGlycoplex is well tolerated by healthy subjects in a clinical trial. Nutr J 2009;8:9. PubMed
- Lyon MR, Reichert RG. The effect of a novel viscous polysaccharide along with lifestyle changes on short-term weight loss and associated risk factors in overweight and obese adults: an observational retrospective clinical program analysis. Altern Med Rev
- Lyon M, Wood S, Pelletier X, et al. Effects of a 3-month supplementation with a novel soluble highly viscous polysaccharide on anthropometry and blood lipids in nondieting overweight or obese adults. J Hum Nutr Diet 2011;24(4):351-9. PubMed
- Han Y, Zhang L, Liu XQ, Zhao ZJ, Lv LX. Effect of glucomannan on functional constipation in children: a systematic review and meta-analysis of randomised controlled trials. Asia Pac J Clin Nutr 2017;26(3):471-7.
- Health Canada Safety Alert. Health Canada Advises Canadians that natural health products containing glucomannan may cause serious choking if used with insufficient fluid. January 29, 2010. Alert # RA-110003825. https://healthycanadians.gc.ca/recall-alert-
- Mortensen A, Aguilar F, Crebelli, et al. EFSA Panel on Food Additives and Nutrient Sources added to Food. Re-evaluation of konjac gum (E 425 i) and konjac glucomannan (E425 ii) as food additives. EFSA Journal 2017;15(6):4864.
- Zhang Y, Aldamarany WAS, Song G, et al. Influence of konjac glucomannan and its derivatives on the oral pharmacokinetics of antimicrobial agent in antibiotics cocktails: Keep vigilant on dietary fiber supplement. Int J Biol Macromol 2023;251:126306. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC