Etoposide

Generic name: Pronounced as (e toe poe' side)
Brand names
  • Vepesid
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Medical Content Reviewed By HelloPharmacist Staff

Last Revised - 10/15/2017

Etoposide can cause a severe decrease in the number of blood cells in your bone marrow. Your doctor will order laboratory tests regularly before and during your treatment. A decrease in the number of blood cells in your body may cause certain symptoms and may increase the risk that you will develop a serious infection or bleeding. If you experience any of the following symptoms, call your doctor immediately: fever, sore throat, ongoing cough and congestion, or other signs of infection; unusual bleeding or bruising; bloody or black, tarry stools; bloody vomit; or vomiting blood or brown material that resembles coffee grounds.

Etoposide is used in combination with other medications to treat a certain type of lung cancer (small cell lung cancer; SCLC). Etoposide is in a class of medications known as podophyllotoxin derivatives. It works by slowing or stopping the growth of cancer cells in your body.

Etoposide comes as a capsule to take by mouth. It is usually taken once a day for 4 or 5 days in a row. This cycle may be repeated once every 3 to 4 weeks, depending on your response to the medication. The length of treatment depends on the types of drugs you are taking, how well your body responds to them, and the type of cancer you have. Take etoposide at around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take etoposide exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Etoposide is also sometimes used to treat certain types of ovarian cancer (cancer that begins in the female reproductive organs where eggs are formed). Talk to your doctor about the risks of using this medication for your condition.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before taking etoposide,

  • tell your doctor and pharmacist if you are allergic to etoposide, any other medications, or any of the ingredients in etoposide capsules. Ask your pharmacist for a list of the ingredients.

  • tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: cisplatin (Platinol), cyclosporine (Gengraf, Neoral, Sandimmune). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Many other medications may also interact with etoposide, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.

  • tell your doctor if you have or have ever had kidney disease.

  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. You should not become pregnant or breast-feed while you are taking etoposide. If you become pregnant while taking etoposide, call your doctor. Etoposide may harm the fetus.

Unless your doctor tells you otherwise, continue your normal diet.

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

  • Etoposide may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

    • nausea

    • vomiting

    • sores in the mouth and throat

    • stomach pain

    • diarrhea

    • constipation

    • loss of appetite or weight

    • unusual tiredness or weakness

    • pale skin

    • fainting

    • dizziness

    • hair loss

    • pain, burning, or tingling in the hands or feet

    • eye pain

    • vision problems

  • Some side effects can be serious. If you experience any of these symptoms or those listed in the IMPORTANT WARNING section, stop taking etoposide and call your doctor immediately or get emergency medical treatment:

    • rash

    • hives

    • itching

    • difficulty breathing or swallowing

    • fast, irregular, or pounding heartbeat

    • seizures

    • yellowing of the skin or eyes

  • Etopside may increase the risk that you will develop other cancers. Talk to your doctor about the risks of taking this medication.

  • Etoposide may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

  • If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, in the refrigerator, tightly closed, and out of reach of children. Do not freeze.

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Keep all appointments with your doctor and the laboratory. Your doctor will order certain tests to check your body's response to etoposide.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

  • VP-16

Drug Interaction
Moxifloxacin Moxifloxacin The metabolism of Etoposide can be decreased when combined with Moxifloxacin.
Insulin Glargine (rDNA origin) Injection Insulin Glargine (rDNA origin) Injection The metabolism of Etoposide can be increased when combined with Insulin glargine.
Leflunomide Leflunomide The risk or severity of adverse effects can be increased when Leflunomide is combined with Etoposide.
Delavirdine Delavirdine The metabolism of Etoposide can be decreased when combined with Delavirdine.
Nevirapine Nevirapine The metabolism of Etoposide can be decreased when combined with Nevirapine.
Atorvastatin Atorvastatin The metabolism of Atorvastatin can be decreased when combined with Etoposide.
Aminophylline Aminophylline The metabolism of Aminophylline can be increased when combined with Etoposide.
Anagrelide Anagrelide The metabolism of Etoposide can be decreased when combined with Anagrelide.
Cilostazol Cilostazol The metabolism of Cilostazol can be decreased when combined with Etoposide.
Clopidogrel Clopidogrel The metabolism of Etoposide can be decreased when combined with Clopidogrel.
Erythromycin and Sulfisoxazole Erythromycin and Sulfisoxazole The serum concentration of Etoposide can be increased when it is combined with Erythromycin.
Estrogen and Progestin (Oral Contraceptives) Estrogen and Progestin (Oral Contraceptives) The metabolism of Etoposide can be decreased when combined with Conjugated estrogens.
Fenofibrate Fenofibrate The metabolism of Fenofibrate can be decreased when combined with Etoposide.
Methylergonovine Methylergonovine The metabolism of Etoposide can be decreased when combined with Methylergometrine.
Mycophenolate Mycophenolate The risk or severity of adverse effects can be increased when Etoposide is combined with Mycophenolic acid.
Paregoric Paregoric The serum concentration of Etoposide can be increased when it is combined with Morphine.
Prednisone Prednisone The risk or severity of adverse effects can be increased when Prednisone is combined with Etoposide.
Ranitidine Ranitidine The metabolism of Ranitidine can be decreased when combined with Etoposide.
Reserpine Reserpine The serum concentration of Etoposide can be increased when it is combined with Reserpine.
Tacrolimus Tacrolimus Tacrolimus may increase the immunosuppressive activities of Etoposide.
Tizanidine Tizanidine The metabolism of Etoposide can be decreased when combined with Tizanidine.
Triamcinolone Triamcinolone The metabolism of Etoposide can be increased when combined with Triamcinolone.
Zolmitriptan Zolmitriptan The metabolism of Etoposide can be decreased when combined with Zolmitriptan.
Doxycycline Injection Doxycycline Injection The metabolism of Etoposide can be decreased when combined with Doxycycline.
Famotidine Injection Famotidine Injection The metabolism of Etoposide can be decreased when combined with Famotidine.
Fluconazole Injection Fluconazole Injection The serum concentration of Etoposide can be increased when it is combined with Fluconazole.
Interferon Beta-1b Injection Interferon Beta-1b Injection The risk or severity of adverse effects can be increased when Interferon beta-1b is combined with Etoposide.
Interferon Gamma-1b Injection Interferon Gamma-1b Injection The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Etoposide.
Levofloxacin Injection Levofloxacin Injection The metabolism of Etoposide can be decreased when combined with Levofloxacin.
Meperidine Injection Meperidine Injection The metabolism of Etoposide can be increased when combined with Meperidine.
Methylprednisolone Injection Methylprednisolone Injection The metabolism of Methylprednisolone can be increased when combined with Etoposide.
Metoclopramide Injection Metoclopramide Injection The metabolism of Metoclopramide can be decreased when combined with Etoposide.
Metronidazole Injection Metronidazole Injection The metabolism of Metronidazole can be decreased when combined with Etoposide.
Morphine Injection Morphine Injection The serum concentration of Etoposide can be increased when it is combined with Morphine.
Zidovudine Injection Zidovudine Injection The metabolism of Etoposide can be increased when combined with Zidovudine.
Cyclosporine Cyclosporine The serum concentration of Etoposide can be increased when it is combined with Cyclosporine.
Ondansetron Ondansetron The metabolism of Etoposide can be decreased when combined with Ondansetron.
Enoxaparin Injection Enoxaparin Injection The risk or severity of bleeding can be increased when Enoxaparin is combined with Etoposide.
Olanzapine Olanzapine The metabolism of Etoposide can be decreased when combined with Olanzapine.
Alosetron Alosetron The metabolism of Etoposide can be decreased when combined with Alosetron.
Dofetilide Dofetilide The metabolism of Dofetilide can be increased when combined with Etoposide.
Hydroxychloroquine Hydroxychloroquine The risk or severity of adverse effects can be increased when Etoposide is combined with Hydroxychloroquine.
Orlistat Orlistat The metabolism of Etoposide can be increased when combined with Orlistat.
Oxcarbazepine Oxcarbazepine The metabolism of Etoposide can be increased when combined with Oxcarbazepine.
Pantoprazole Pantoprazole Pantoprazole may decrease the excretion rate of Etoposide which could result in a higher serum level.
Telmisartan Telmisartan Telmisartan may decrease the excretion rate of Etoposide which could result in a higher serum level.
Temozolomide Temozolomide The risk or severity of adverse effects can be increased when Etoposide is combined with Temozolomide.
Zaleplon Zaleplon The metabolism of Zaleplon can be decreased when combined with Etoposide.
Anakinra Anakinra The metabolism of Etoposide can be increased when combined with Anakinra.
Linezolid Linezolid The risk or severity of adverse effects can be increased when Linezolid is combined with Etoposide.
Pentosan Polysulfate Pentosan Polysulfate The risk or severity of bleeding can be increased when Pentosan polysulfate is combined with Etoposide.
Trimipramine Trimipramine The serum concentration of Trimipramine can be increased when it is combined with Etoposide.
Etanercept Injection Etanercept Injection The metabolism of Etoposide can be increased when combined with Etanercept.
Modafinil Modafinil The metabolism of Etoposide can be increased when combined with Modafinil.
Tenofovir Tenofovir The metabolism of Tenofovir can be decreased when combined with Etoposide.
Sirolimus Sirolimus The metabolism of Sirolimus can be increased when combined with Etoposide.
Dutasteride Dutasteride The metabolism of Dutasteride can be decreased when combined with Etoposide.
Epinephrine Injection Epinephrine Injection The metabolism of Etoposide can be decreased when combined with Epinephrine.
Epirubicin Epirubicin The risk or severity of adverse effects can be increased when Epirubicin is combined with Etoposide.
Eplerenone Eplerenone The metabolism of Etoposide can be decreased when combined with Eplerenone.
Zonisamide Zonisamide The serum concentration of Etoposide can be increased when it is combined with Zonisamide.
Adalimumab Injection Adalimumab Injection The metabolism of Etoposide can be increased when combined with Adalimumab.
Aripiprazole Aripiprazole The metabolism of Aripiprazole can be increased when combined with Etoposide.
Glatiramer Injection Glatiramer Injection The risk or severity of adverse effects can be increased when Etoposide is combined with Glatiramer.
Atazanavir Atazanavir The metabolism of Atazanavir can be decreased when combined with Etoposide.
Mefloquine Mefloquine The metabolism of Etoposide can be decreased when combined with Mefloquine.
Rosuvastatin Rosuvastatin The metabolism of Rosuvastatin can be decreased when combined with Etoposide.
Vardenafil Vardenafil The metabolism of Vardenafil can be decreased when combined with Etoposide.
Alfuzosin Alfuzosin The metabolism of Alfuzosin can be decreased when combined with Etoposide.
Aprepitant Aprepitant The metabolism of Etoposide can be decreased when combined with Aprepitant.
Interferon Beta-1a Subcutaneous Injection Interferon Beta-1a Subcutaneous Injection The metabolism of Etoposide can be decreased when combined with Interferon beta-1a.
Tegaserod Tegaserod The metabolism of Etoposide can be decreased when combined with Tegaserod.
Tadalafil Tadalafil The metabolism of Tadalafil can be decreased when combined with Etoposide.
Frovatriptan Frovatriptan The metabolism of Frovatriptan can be decreased when combined with Etoposide.
Gemifloxacin Gemifloxacin The metabolism of Etoposide can be decreased when combined with Gemifloxacin.
Progesterone Progesterone The metabolism of Etoposide can be increased when combined with Progesterone.
Apomorphine Injection Apomorphine Injection The metabolism of Etoposide can be decreased when combined with Apomorphine.
Darbepoetin Alfa Injection Darbepoetin Alfa Injection The risk or severity of Thrombosis can be increased when Darbepoetin alfa is combined with Etoposide.
Infliximab Injection Infliximab Injection The metabolism of Etoposide can be increased when combined with Infliximab.
Rifaximin Rifaximin The metabolism of Etoposide can be increased when combined with Rifaximin.
Duloxetine Duloxetine The metabolism of Duloxetine can be decreased when combined with Etoposide.
Norethindrone Norethindrone The metabolism of Norethisterone can be decreased when combined with Etoposide.
Bosentan Bosentan The metabolism of Etoposide can be increased when combined with Bosentan.
Cinacalcet Cinacalcet The metabolism of Cinacalcet can be decreased when combined with Etoposide.
Natalizumab Injection Natalizumab Injection The risk or severity of adverse effects can be increased when Etoposide is combined with Natalizumab.
Erlotinib Erlotinib The serum concentration of Erlotinib can be decreased when it is combined with Etoposide.
Eszopiclone Eszopiclone The serum concentration of Eszopiclone can be decreased when it is combined with Etoposide.
Palifermin Palifermin The therapeutic efficacy of Palifermin can be decreased when used in combination with Etoposide.
Voriconazole Voriconazole The metabolism of Etoposide can be decreased when combined with Voriconazole.
Entecavir Entecavir The metabolism of Etoposide can be decreased when combined with Entecavir.
Peginterferon Alfa-2a Injection Peginterferon Alfa-2a Injection The risk or severity of adverse effects can be increased when Peginterferon alfa-2a is combined with Etoposide.
Peginterferon Alfa-2b (PEG-Intron) Peginterferon Alfa-2b (PEG-Intron) The serum concentration of Etoposide can be increased when it is combined with Peginterferon alfa-2b.
Ramelteon Ramelteon The metabolism of Ramelteon can be decreased when combined with Etoposide.
Fentanyl Fentanyl The metabolism of Fentanyl can be decreased when combined with Etoposide.
Deferasirox Deferasirox The serum concentration of Etoposide can be increased when it is combined with Deferasirox.
Phenylephrine Phenylephrine The metabolism of Etoposide can be increased when combined with Phenylephrine.
Tipranavir Tipranavir The serum concentration of Etoposide can be increased when it is combined with Tipranavir.
Felbamate Felbamate The metabolism of Etoposide can be increased when combined with Felbamate.
Ranolazine Ranolazine The metabolism of Etoposide can be increased when combined with Ranolazine.
Abatacept Injection Abatacept Injection The metabolism of Etoposide can be increased when combined with Abatacept.
Rasagiline Rasagiline The metabolism of Rasagiline can be decreased when combined with Etoposide.
Imatinib Imatinib The metabolism of Etoposide can be decreased when combined with Imatinib.
Sitagliptin Sitagliptin The serum concentration of Sitagliptin can be increased when it is combined with Etoposide.
Bevacizumab Injection Bevacizumab Injection The risk or severity of adverse effects can be increased when Bevacizumab is combined with Etoposide.
Gefitinib Gefitinib The metabolism of Etoposide can be decreased when combined with Gefitinib.
Paliperidone Paliperidone The serum concentration of Paliperidone can be increased when it is combined with Etoposide.
Bortezomib Bortezomib The metabolism of Etoposide can be increased when combined with Bortezomib.
Clofarabine Injection Clofarabine Injection The risk or severity of adverse effects can be increased when Clofarabine is combined with Etoposide.
Hepatitis B Vaccine Hepatitis B Vaccine The therapeutic efficacy of Hepatitis B Vaccine (Recombinant) can be decreased when used in combination with Etoposide.
Influenza Vaccine, Inactivated or Recombinant Influenza Vaccine, Inactivated or Recombinant The therapeutic efficacy of Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated) can be decreased when used in combination with Etoposide.
Influenza Vaccine, Live Intranasal Influenza Vaccine, Live Intranasal The risk or severity of infection can be increased when Typhoid Vaccine Live is combined with Etoposide.
Live Shingles (Zoster) Vaccine (ZVL) Live Shingles (Zoster) Vaccine (ZVL) The risk or severity of infection can be increased when Varicella Zoster Vaccine (Live/attenuated) is combined with Etoposide.
Insulin Glulisine (rDNA origin) Injection Insulin Glulisine (rDNA origin) Injection The metabolism of Etoposide can be increased when combined with Insulin glulisine.
Oxaliplatin Injection Oxaliplatin Injection The risk or severity of adverse effects can be increased when Oxaliplatin is combined with Etoposide.
Posaconazole Posaconazole The metabolism of Posaconazole can be decreased when combined with Etoposide.
Primaquine Primaquine The metabolism of Etoposide can be decreased when combined with Primaquine.
Rituximab Injection Rituximab Injection The risk or severity of adverse effects can be increased when Rituximab is combined with Etoposide.
Darunavir Darunavir The serum concentration of Etoposide can be increased when it is combined with Darunavir.
Pemetrexed Injection Pemetrexed Injection The risk or severity of adverse effects can be increased when Pemetrexed is combined with Etoposide.
Retapamulin Retapamulin The metabolism of Retapamulin can be decreased when combined with Etoposide.
Vorinostat Vorinostat The risk or severity of adverse effects can be increased when Etoposide is combined with Vorinostat.
Sorafenib Sorafenib The serum concentration of Etoposide can be increased when it is combined with Sorafenib.
Sunitinib Sunitinib The metabolism of Sunitinib can be increased when combined with Etoposide.
Dronabinol Dronabinol Dronabinol may decrease the excretion rate of Etoposide which could result in a higher serum level.
Lapatinib Lapatinib The serum concentration of Etoposide can be increased when it is combined with Lapatinib.
Dasatinib Dasatinib The metabolism of Dasatinib can be increased when combined with Etoposide.
Mexiletine Mexiletine The metabolism of Etoposide can be decreased when combined with Mexiletine.
Armodafinil Armodafinil The metabolism of Etoposide can be increased when combined with Armodafinil.
Azacitidine Injection Azacitidine Injection The risk or severity of adverse effects can be increased when Etoposide is combined with Azacitidine.
Ivermectin Ivermectin The metabolism of Etoposide can be increased when combined with Ivermectin.
Temsirolimus Temsirolimus The metabolism of Etoposide can be decreased when combined with Temsirolimus.
Nelarabine Injection Nelarabine Injection The risk or severity of adverse effects can be increased when Etoposide is combined with Nelarabine.
Lenalidomide Lenalidomide The risk or severity of adverse effects can be increased when Lenalidomide is combined with Etoposide.
Nilotinib Nilotinib The serum concentration of Nilotinib can be increased when it is combined with Etoposide.
Toremifene Toremifene The serum concentration of Etoposide can be increased when it is combined with Toremifene.
Bexarotene Bexarotene The metabolism of Etoposide can be increased when combined with Bexarotene.
Budesonide Budesonide The metabolism of Etoposide can be increased when combined with Budesonide.
Chloramphenicol Injection Chloramphenicol Injection The metabolism of Etoposide can be decreased when combined with Chloramphenicol.
Decitabine Injection Decitabine Injection The risk or severity of adverse effects can be increased when Etoposide is combined with Decitabine.
Etravirine Etravirine The metabolism of Etoposide can be increased when combined with Etravirine.
Arsenic Trioxide Injection Arsenic Trioxide Injection The risk or severity of adverse effects can be increased when Etoposide is combined with Arsenic trioxide.
Mitoxantrone Injection Mitoxantrone Injection The metabolism of Mitoxantrone can be decreased when combined with Etoposide.
Desvenlafaxine Desvenlafaxine The metabolism of Etoposide can be decreased when combined with Desvenlafaxine.
Tretinoin Tretinoin The metabolism of Etoposide can be decreased when combined with Tretinoin.
Bendamustine Injection Bendamustine Injection The risk or severity of adverse effects can be increased when Etoposide is combined with Bendamustine.
Pilocarpine Pilocarpine The metabolism of Etoposide can be decreased when combined with Pilocarpine.
Flecainide Flecainide The metabolism of Flecainide can be decreased when combined with Etoposide.
Certolizumab Injection Certolizumab Injection The metabolism of Etoposide can be increased when combined with Certolizumab pegol.
Ixabepilone Injection Ixabepilone Injection The metabolism of Ixabepilone can be increased when combined with Etoposide.
Irinotecan Injection Irinotecan Injection The metabolism of Etoposide can be decreased when combined with Irinotecan.
Estramustine Estramustine The risk or severity of adverse effects can be increased when Etoposide is combined with Estramustine.
Praziquantel Praziquantel The metabolism of Praziquantel can be decreased when combined with Etoposide.
Mitotane Mitotane The metabolism of Etoposide can be increased when combined with Mitotane.
Alemtuzumab Injection (Chronic Lymphocytic Leukemia) Alemtuzumab Injection (Chronic Lymphocytic Leukemia) The risk or severity of adverse effects can be increased when Alemtuzumab is combined with Etoposide.
Rufinamide Rufinamide The metabolism of Rufinamide can be increased when combined with Etoposide.
Silodosin Silodosin The serum concentration of Silodosin can be increased when it is combined with Etoposide.
Midazolam Midazolam The serum concentration of Midazolam can be increased when it is combined with Etoposide.
Dexrazoxane Injection Dexrazoxane Injection The risk or severity of adverse effects can be increased when Dexrazoxane is combined with Etoposide.
Eltrombopag Eltrombopag The metabolism of Etoposide can be decreased when combined with Eltrombopag.
Ibritumomab Injection Ibritumomab Injection The risk or severity of adverse effects can be increased when Ibritumomab tiuxetan is combined with Etoposide.
Milnacipran Milnacipran The metabolism of Milnacipran can be increased when combined with Etoposide.
Betaxolol Betaxolol The metabolism of Etoposide can be decreased when combined with Betaxolol.
Iloperidone Iloperidone The metabolism of Iloperidone can be decreased when combined with Etoposide.
Prasugrel Prasugrel The risk or severity of bleeding can be increased when Prasugrel is combined with Etoposide.
Lacosamide Lacosamide The metabolism of Lacosamide can be decreased when combined with Etoposide.
Everolimus Everolimus The metabolism of Etoposide can be increased when combined with Everolimus.
Tolvaptan (low blood sodium) Tolvaptan (low blood sodium) The metabolism of Tolvaptan can be increased when combined with Etoposide.
Dronedarone Dronedarone The serum concentration of Dronedarone can be increased when it is combined with Etoposide.
Pralatrexate Injection Pralatrexate Injection The risk or severity of adverse effects can be increased when Etoposide is combined with Pralatrexate.
Saxagliptin Saxagliptin The metabolism of Saxagliptin can be decreased when combined with Etoposide.
Romidepsin Injection Romidepsin Injection The metabolism of Romidepsin can be decreased when combined with Etoposide.
Topotecan Topotecan The metabolism of Topotecan can be increased when combined with Etoposide.
Golimumab Injection Golimumab Injection The metabolism of Etoposide can be increased when combined with Golimumab.
Pazopanib Pazopanib The metabolism of Pazopanib can be increased when combined with Etoposide.
Asenapine Asenapine The metabolism of Asenapine can be decreased when combined with Etoposide.
Albendazole Albendazole The metabolism of Albendazole can be decreased when combined with Etoposide.
Ulipristal Ulipristal The metabolism of Ulipristal can be increased when combined with Etoposide.
Levonorgestrel Levonorgestrel The metabolism of Levonorgestrel can be decreased when combined with Etoposide.
Denosumab Injection Denosumab Injection The risk or severity of adverse effects can be increased when Denosumab is combined with Etoposide.
Dabigatran Dabigatran The risk or severity of bleeding can be increased when Dabigatran is combined with Etoposide.
Tocilizumab Injection Tocilizumab Injection The metabolism of Etoposide can be increased when combined with Tocilizumab.
Fingolimod Fingolimod Etoposide may increase the immunosuppressive activities of Fingolimod.
Eribulin Injection Eribulin Injection The risk or severity of adverse effects can be increased when Etoposide is combined with Eribulin.
Cabazitaxel Injection Cabazitaxel Injection The metabolism of Cabazitaxel can be decreased when combined with Etoposide.
Acetaminophen Injection Acetaminophen Injection The metabolism of Etoposide can be increased when combined with Acetaminophen.
Denileukin Diftitox Injection Denileukin Diftitox Injection The metabolism of Etoposide can be decreased when combined with Aldesleukin.
Sipuleucel-T Injection Sipuleucel-T Injection The therapeutic efficacy of Sipuleucel-T can be decreased when used in combination with Etoposide.
Belimumab Injection Belimumab Injection The risk or severity of adverse effects can be increased when Etoposide is combined with Belimumab.
Busulfan Injection Busulfan Injection The metabolism of Busulfan can be increased when combined with Etoposide.
Roflumilast Roflumilast Roflumilast may increase the immunosuppressive activities of Etoposide.
Linagliptin Linagliptin The serum concentration of Linagliptin can be increased when it is combined with Etoposide.
Rilpivirine Rilpivirine The metabolism of Etoposide can be decreased when combined with Rilpivirine.
Telaprevir Telaprevir The serum concentration of Etoposide can be increased when it is combined with Glecaprevir.
Cyclophosphamide Injection Cyclophosphamide Injection The metabolism of Etoposide can be increased when combined with Cyclophosphamide.
Abiraterone Abiraterone The serum concentration of Etoposide can be increased when it is combined with Abiraterone.
Rivaroxaban Rivaroxaban The metabolism of Rivaroxaban can be decreased when combined with Etoposide.
Ticagrelor Ticagrelor The serum concentration of Etoposide can be increased when it is combined with Ticagrelor.
Brentuximab Vedotin Injection Brentuximab Vedotin Injection The metabolism of Brentuximab vedotin can be increased when combined with Etoposide.
Ruxolitinib Ruxolitinib The metabolism of Ruxolitinib can be increased when combined with Etoposide.
Vandetanib Vandetanib The metabolism of Etoposide can be increased when combined with Vandetanib.
Clobazam Clobazam The metabolism of Etoposide can be increased when combined with Clobazam.
Vemurafenib Vemurafenib The serum concentration of Etoposide can be increased when it is combined with Vemurafenib.
Vismodegib Vismodegib Vismodegib may decrease the excretion rate of Etoposide which could result in a higher serum level.
Belatacept Injection Belatacept Injection The risk or severity of adverse effects can be increased when Etoposide is combined with Belatacept.
Ivacaftor Ivacaftor The serum concentration of Etoposide can be increased when it is combined with Ivacaftor.
Basiliximab Injection Basiliximab Injection The risk or severity of adverse effects can be increased when Basiliximab is combined with Etoposide.
Axitinib Axitinib The metabolism of Axitinib can be increased when combined with Etoposide.
Crizotinib Crizotinib The metabolism of Crizotinib can be decreased when combined with Etoposide.
Melphalan Injection Melphalan Injection The risk or severity of adverse effects can be increased when Etoposide is combined with Melphalan.
Cabergoline Cabergoline The metabolism of Cabergoline can be increased when combined with Etoposide.
Naloxone Injection Naloxone Injection The metabolism of Etoposide can be decreased when combined with Naloxone.
Ambrisentan Ambrisentan The metabolism of Ambrisentan can be decreased when combined with Etoposide.
Eculizumab Injection Eculizumab Injection The risk or severity of adverse effects can be increased when Etoposide is combined with Eculizumab.
Fondaparinux Injection Fondaparinux Injection The risk or severity of bleeding can be increased when Fondaparinux is combined with Etoposide.
Pertuzumab Injection Pertuzumab Injection The risk or severity of cardiotoxicity can be increased when Etoposide is combined with Pertuzumab.
Carfilzomib Injection Carfilzomib Injection The serum concentration of Carfilzomib can be increased when it is combined with Etoposide.
Iloprost Iloprost The risk or severity of bleeding can be increased when Iloprost is combined with Etoposide.
Enzalutamide Enzalutamide The serum concentration of Etoposide can be increased when it is combined with Enzalutamide.
Mirabegron Mirabegron The serum concentration of Mirabegron can be increased when it is combined with Etoposide.
Regorafenib Regorafenib The serum concentration of Etoposide can be increased when it is combined with Regorafenib.
Bosutinib Bosutinib The metabolism of Bosutinib can be increased when combined with Etoposide.
Corticotropin, Repository Injection Corticotropin, Repository Injection The metabolism of Corticotropin can be increased when combined with Etoposide.
Teriflunomide Teriflunomide The serum concentration of Etoposide can be decreased when it is combined with Teriflunomide.
Icosapent Ethyl Icosapent Ethyl The risk or severity of bleeding can be increased when Icosapent ethyl is combined with Etoposide.
Tofacitinib Tofacitinib Etoposide may increase the immunosuppressive activities of Tofacitinib.
Dimethyl Fumarate Dimethyl Fumarate The risk or severity of adverse effects can be increased when Etoposide is combined with Dimethyl fumarate.
Ponatinib Ponatinib The serum concentration of Ponatinib can be increased when it is combined with Etoposide.
Pomalidomide Pomalidomide The metabolism of Pomalidomide can be increased when combined with Etoposide.
Ado-trastuzumab Emtansine Injection Ado-trastuzumab Emtansine Injection The metabolism of Trastuzumab emtansine can be decreased when combined with Etoposide.
Apixaban Apixaban The metabolism of Apixaban can be decreased when combined with Etoposide.
Canagliflozin Canagliflozin The serum concentration of Canagliflozin can be increased when it is combined with Etoposide.
Dabrafenib Dabrafenib The metabolism of Etoposide can be increased when combined with Dabrafenib.
Trametinib Trametinib The metabolism of Etoposide can be increased when combined with Trametinib.
Dolutegravir Dolutegravir The serum concentration of Dolutegravir can be increased when it is combined with Etoposide.
Afatinib Afatinib The serum concentration of Etoposide can be increased when it is combined with Afatinib.
Levomilnacipran Levomilnacipran The metabolism of Levomilnacipran can be increased when combined with Etoposide.
Vortioxetine Vortioxetine The metabolism of Vortioxetine can be decreased when combined with Etoposide.
Perampanel Perampanel The metabolism of Perampanel can be increased when combined with Etoposide.
Ibrutinib Ibrutinib The metabolism of Ibrutinib can be decreased when combined with Etoposide.
Lomitapide Lomitapide The serum concentration of Etoposide can be increased when it is combined with Lomitapide.
Obinutuzumab Injection Obinutuzumab Injection The risk or severity of adverse effects can be increased when Etoposide is combined with Obinutuzumab.
Simeprevir Simeprevir The serum concentration of Etoposide can be increased when it is combined with Simeprevir.
Sofosbuvir Sofosbuvir The serum concentration of Sofosbuvir can be increased when it is combined with Etoposide.
Dapagliflozin Dapagliflozin The metabolism of Etoposide can be decreased when combined with Dapagliflozin.
Apremilast Apremilast The metabolism of Etoposide can be increased when combined with Apremilast.
Ceritinib Ceritinib The metabolism of Ceritinib can be increased when combined with Etoposide.
Siltuximab Injection Siltuximab Injection The metabolism of Etoposide can be increased when combined with Siltuximab.
Eslicarbazepine Eslicarbazepine The metabolism of Etoposide can be increased when combined with Eslicarbazepine.
Vedolizumab Injection Vedolizumab Injection The risk or severity of adverse effects can be increased when Etoposide is combined with Vedolizumab.
Belinostat Injection Belinostat Injection The risk or severity of adverse effects can be increased when Etoposide is combined with Belinostat.
Idelalisib Idelalisib The metabolism of Idelalisib can be increased when combined with Etoposide.
Testosterone Injection Testosterone Injection The metabolism of Etoposide can be increased when combined with Testosterone.
Oritavancin Injection Oritavancin Injection The metabolism of Etoposide can be increased when combined with Oritavancin.
Vorapaxar Vorapaxar The serum concentration of Etoposide can be increased when it is combined with Vorapaxar.
Suvorexant Suvorexant The serum concentration of Etoposide can be increased when it is combined with Suvorexant.
Edoxaban Edoxaban The serum concentration of Edoxaban can be increased when it is combined with Etoposide.
Peginterferon Beta-1a Injection Peginterferon Beta-1a Injection The risk or severity of adverse effects can be increased when Etoposide is combined with Peginterferon beta-1a.
Olaparib Olaparib The metabolism of Olaparib can be decreased when combined with Etoposide.
Blinatumomab Injection Blinatumomab Injection The risk or severity of adverse effects can be increased when Etoposide is combined with Blinatumomab.
Tasimelteon Tasimelteon The metabolism of Tasimelteon can be decreased when combined with Etoposide.
Lanreotide Injection Lanreotide Injection The metabolism of Etoposide can be decreased when combined with Lanreotide.
Pirfenidone Pirfenidone The risk or severity of adverse effects can be increased when Etoposide is combined with Pirfenidone.
Nintedanib Nintedanib The metabolism of Nintedanib can be decreased when combined with Etoposide.
Secukinumab Injection Secukinumab Injection The metabolism of Etoposide can be increased when combined with Secukinumab.
Risperidone Injection Risperidone Injection The metabolism of Etoposide can be decreased when combined with Risperidone.
Palbociclib Palbociclib The serum concentration of Palbociclib can be increased when it is combined with Etoposide.
Insulin Human Inhalation Insulin Human Inhalation The metabolism of Etoposide can be increased when combined with Insulin human.
Lenvatinib Lenvatinib The metabolism of Lenvatinib can be increased when combined with Etoposide.
Panobinostat Panobinostat The metabolism of Panobinostat can be increased when combined with Etoposide.
Dinutuximab Injection Dinutuximab Injection The risk or severity of adverse effects can be increased when Etoposide is combined with Dinutuximab.
Haloperidol Injection Haloperidol Injection The serum concentration of Etoposide can be increased when it is combined with Haloperidol.
Isavuconazonium Injection Isavuconazonium Injection The serum concentration of Etoposide can be increased when it is combined with Isavuconazonium.
Sonidegib Sonidegib The metabolism of Sonidegib can be increased when combined with Etoposide.
Flibanserin Flibanserin The serum concentration of Etoposide can be increased when it is combined with Flibanserin.
Rolapitant Rolapitant The serum concentration of Etoposide can be increased when it is combined with Rolapitant.
Prednisolone Prednisolone The metabolism of Prednisolone can be increased when combined with Etoposide.
Daclatasvir Daclatasvir The serum concentration of Etoposide can be increased when it is combined with Daclatasvir.
Ziprasidone Injection Ziprasidone Injection The metabolism of Etoposide can be decreased when combined with Ziprasidone.
Insulin Degludec (rDNA Origin) Injection Insulin Degludec (rDNA Origin) Injection The metabolism of Etoposide can be increased when combined with Insulin degludec.
Cobimetinib Cobimetinib The metabolism of Cobimetinib can be increased when combined with Etoposide.
Mepolizumab Injection Mepolizumab Injection The risk or severity of adverse effects can be increased when Etoposide is combined with Mepolizumab.
Trabectedin Injection Trabectedin Injection The metabolism of Trabectedin can be increased when combined with Etoposide.
Osimertinib Osimertinib The serum concentration of Etoposide can be decreased when it is combined with Osimertinib.
Alectinib Alectinib The metabolism of Etoposide can be increased when combined with Alectinib.
Ixazomib Ixazomib The metabolism of Ixazomib can be increased when combined with Etoposide.
Rifapentine Rifapentine The metabolism of Etoposide can be increased when combined with Rifapentine.
Lesinurad Lesinurad The metabolism of Etoposide can be increased when combined with Lesinurad.
Amphotericin B Liposomal Injection Amphotericin B Liposomal Injection The metabolism of Etoposide can be decreased when combined with Amphotericin B.
Dexamethasone Injection Dexamethasone Injection The metabolism of Dexamethasone can be increased when combined with Etoposide.
Defibrotide Injection Defibrotide Injection The risk or severity of bleeding can be increased when Defibrotide is combined with Etoposide.
Ixekizumab Injection Ixekizumab Injection The risk or severity of adverse effects can be increased when Etoposide is combined with Ixekizumab.
Venetoclax Venetoclax The metabolism of Venetoclax can be increased when combined with Etoposide.
Cobicistat Cobicistat The serum concentration of Etoposide can be increased when it is combined with Cobicistat.
Selexipag Selexipag The serum concentration of Selexipag can be increased when it is combined with Etoposide.
Obeticholic Acid Obeticholic Acid The risk or severity of adverse effects can be increased when Obeticholic acid is combined with Etoposide.
Rucaparib Rucaparib The serum concentration of Etoposide can be increased when it is combined with Rucaparib.
Ribociclib Ribociclib The metabolism of Ribociclib can be decreased when combined with Etoposide.
Brodalumab Injection Brodalumab Injection The risk or severity of adverse effects can be increased when Etoposide is combined with Brodalumab.
Brigatinib Brigatinib The metabolism of Etoposide can be increased when combined with Brigatinib.
Doxepin (Insomnia) Doxepin (Insomnia) The metabolism of Doxepin can be decreased when combined with Etoposide.
Deutetrabenazine Deutetrabenazine The metabolism of Deutetrabenazine can be decreased when combined with Etoposide.
Valbenazine Valbenazine The metabolism of Valbenazine can be decreased when combined with Etoposide.
Deflazacort Deflazacort The metabolism of Deflazacort can be increased when combined with Etoposide.
Safinamide Safinamide The metabolism of Etoposide can be decreased when combined with Safinamide.
Ocrelizumab Injection Ocrelizumab Injection Ocrelizumab may increase the immunosuppressive activities of Etoposide.
Sarilumab Injection Sarilumab Injection The metabolism of Sarilumab can be increased when combined with Etoposide.
Midostaurin Midostaurin The metabolism of Etoposide can be increased when combined with Midostaurin.
Neratinib Neratinib The serum concentration of Etoposide can be increased when it is combined with Neratinib.
Guselkumab Injection Guselkumab Injection The risk or severity of adverse effects can be increased when Etoposide is combined with Guselkumab.
Enasidenib Enasidenib The metabolism of Etoposide can be increased when combined with Enasidenib.
Inotuzumab Ozogamicin Injection Inotuzumab Ozogamicin Injection The serum concentration of Inotuzumab ozogamicin can be increased when it is combined with Etoposide.
Aprepitant/Fosaprepitant Injection Aprepitant/Fosaprepitant Injection The metabolism of Fosaprepitant can be increased when combined with Etoposide.
Copanlisib Injection Copanlisib Injection The metabolism of Copanlisib can be increased when combined with Etoposide.
Abemaciclib Abemaciclib The metabolism of Etoposide can be increased when combined with Abemaciclib.
Betrixaban Betrixaban The serum concentration of Betrixaban can be increased when it is combined with Etoposide.
Acalabrutinib Acalabrutinib The metabolism of Etoposide can be increased when combined with Acalabrutinib.
Gemtuzumab Ozogamicin Injection Gemtuzumab Ozogamicin Injection The risk or severity of adverse effects can be increased when Gemtuzumab ozogamicin is combined with Etoposide.
Letermovir Letermovir The metabolism of Etoposide can be decreased when combined with Letermovir.
Ertugliflozin Ertugliflozin The metabolism of Etoposide can be decreased when combined with Ertugliflozin.
Buprenorphine Injection Buprenorphine Injection The metabolism of Etoposide can be decreased when combined with Buprenorphine.
Apalutamide Apalutamide The serum concentration of Etoposide can be decreased when it is combined with Apalutamide.
Penicillamine Penicillamine The risk or severity of adverse effects can be increased when Etoposide is combined with Penicillamine.
Fostamatinib Fostamatinib The metabolism of Etoposide can be decreased when combined with Fostamatinib.
Avatrombopag Avatrombopag Avatrombopag may decrease the excretion rate of Etoposide which could result in a higher serum level.
Baricitinib Baricitinib The metabolism of Baricitinib can be increased when combined with Etoposide.
Lofexidine Lofexidine The metabolism of Lofexidine can be decreased when combined with Etoposide.
Eliglustat Eliglustat The metabolism of Eliglustat can be decreased when combined with Etoposide.
Binimetinib Binimetinib The metabolism of Binimetinib can be decreased when combined with Etoposide.
Ivosidenib Ivosidenib The serum concentration of Ivosidenib can be increased when it is combined with Etoposide.
Lusutrombopag Lusutrombopag The serum concentration of Lusutrombopag can be increased when it is combined with Etoposide.
Elagolix Elagolix The serum concentration of Elagolix can be increased when it is combined with Etoposide.
Doravirine Doravirine The metabolism of Doravirine can be decreased when combined with Etoposide.
Cannabidiol Cannabidiol The metabolism of Etoposide can be decreased when combined with Cannabidiol.
Dacomitinib Dacomitinib The serum concentration of Etoposide can be increased when it is combined with Dacomitinib.
Duvelisib Duvelisib The metabolism of Duvelisib can be decreased when combined with Etoposide.
Omadacycline Omadacycline The serum concentration of Omadacycline can be increased when it is combined with Etoposide.
Sarecycline Sarecycline The serum concentration of Etoposide can be increased when it is combined with Sarecycline.
Stiripentol Stiripentol The metabolism of Etoposide can be decreased when combined with Stiripentol.
Talazoparib Talazoparib The serum concentration of Talazoparib can be increased when it is combined with Etoposide.
Gilteritinib Gilteritinib The metabolism of Etoposide can be decreased when combined with Gilteritinib.
Glasdegib Glasdegib The serum concentration of Glasdegib can be increased when it is combined with Etoposide.
Lorlatinib Lorlatinib The metabolism of Lorlatinib can be decreased when combined with Etoposide.
Larotrectinib Larotrectinib The serum concentration of Larotrectinib can be increased when it is combined with Etoposide.
Methoxy Polyethylene Glycol-Epoetin Beta Injection Methoxy Polyethylene Glycol-Epoetin Beta Injection The risk or severity of Thrombosis can be increased when Methoxy polyethylene glycol-epoetin beta is combined with Etoposide.
Paclitaxel (with albumin) Injection Paclitaxel (with albumin) Injection The metabolism of Paclitaxel can be increased when combined with Etoposide.
Rifamycin Rifamycin The serum concentration of Rifamycin can be increased when it is combined with Etoposide.
Prucalopride Prucalopride The metabolism of Prucalopride can be decreased when combined with Etoposide.
Ravulizumab-cwvz Injection Ravulizumab-cwvz Injection The risk or severity of adverse effects can be increased when Etoposide is combined with Ravulizumab.
Emapalumab-lzsg Injection Emapalumab-lzsg Injection The metabolism of Etoposide can be increased when combined with Emapalumab.
Siponimod Siponimod The metabolism of Siponimod can be increased when combined with Etoposide.
Acyclovir Ophthalmic Acyclovir Ophthalmic The metabolism of Acyclovir can be decreased when combined with Etoposide.
Caplacizumab-yhdp Injection Caplacizumab-yhdp Injection The risk or severity of bleeding can be increased when Caplacizumab is combined with Etoposide.
Erdafitinib Erdafitinib The serum concentration of Etoposide can be increased when it is combined with Erdafitinib.
Risankizumab-rzaa Injection Risankizumab-rzaa Injection The risk or severity of adverse effects can be increased when Etoposide is combined with Risankizumab.
Alpelisib Alpelisib The metabolism of Alpelisib can be increased when combined with Etoposide.
Cladribine Cladribine The risk or severity of adverse effects can be increased when Cladribine is combined with Etoposide.
Darolutamide Darolutamide The serum concentration of Etoposide can be increased when it is combined with Darolutamide.
Triclabendazole Triclabendazole The metabolism of Etoposide can be decreased when combined with Triclabendazole.
Entrectinib Entrectinib The metabolism of Entrectinib can be increased when combined with Etoposide.
Pexidartinib Pexidartinib The metabolism of Etoposide can be increased when combined with Pexidartinib.
Istradefylline Istradefylline The serum concentration of Istradefylline can be increased when it is combined with Etoposide.
Pitolisant Pitolisant The serum concentration of Etoposide can be decreased when it is combined with Pitolisant.
Fedratinib Fedratinib The serum concentration of Etoposide can be increased when it is combined with Fedratinib.
Lefamulin Lefamulin The serum concentration of Lefamulin can be increased when it is combined with Etoposide.
Phenytoin Injection Phenytoin Injection The metabolism of Etoposide can be increased when combined with Phenytoin.
Fosphenytoin Injection Fosphenytoin Injection The metabolism of Fosphenytoin can be decreased when combined with Etoposide.
Enfortumab vedotin-ejfv Injection Enfortumab vedotin-ejfv Injection The serum concentration of Enfortumab vedotin can be increased when it is combined with Etoposide.
Zanubrutinib Zanubrutinib The metabolism of Zanubrutinib can be increased when combined with Etoposide.
Voxelotor Voxelotor The serum concentration of Voxelotor can be increased when it is combined with Etoposide.
Lumateperone Lumateperone The serum concentration of Lumateperone can be decreased when it is combined with Etoposide.
Lasmiditan Lasmiditan The serum concentration of Etoposide can be increased when it is combined with Lasmiditan.
Ubrogepant Ubrogepant The serum concentration of Ubrogepant can be increased when it is combined with Etoposide.
Tazemetostat Tazemetostat The metabolism of Tazemetostat can be decreased when combined with Etoposide.
Cenobamate Cenobamate The serum concentration of Etoposide can be decreased when it is combined with Cenobamate.
Ozanimod Ozanimod The risk or severity of adverse effects can be increased when Etoposide is combined with Ozanimod.
Selumetinib Selumetinib The metabolism of Selumetinib can be decreased when combined with Etoposide.
Rimegepant Rimegepant The metabolism of Rimegepant can be increased when combined with Etoposide.
Tucatinib Tucatinib Etoposide may decrease the excretion rate of Tucatinib which could result in a higher serum level.
Remdesivir Injection Remdesivir Injection The serum concentration of Etoposide can be increased when it is combined with Remdesivir.
Ripretinib Ripretinib The serum concentration of Etoposide can be increased when it is combined with Ripretinib.
Selpercatinib Selpercatinib The serum concentration of Selpercatinib can be decreased when it is combined with Etoposide.
Capmatinib Capmatinib The serum concentration of Capmatinib can be decreased when it is combined with Etoposide.
Lemborexant Lemborexant The serum concentration of Lemborexant can be decreased when it is combined with Etoposide.
Fostemsavir Fostemsavir Fostemsavir may decrease the excretion rate of Etoposide which could result in a higher serum level.
Octreotide Octreotide The serum concentration of Etoposide can be increased when it is combined with Octreotide.
Belantamab Mafodotin-blmf Injection Belantamab Mafodotin-blmf Injection The serum concentration of Etoposide can be increased when it is combined with Belantamab mafodotin.
Pralsetinib Pralsetinib The serum concentration of Etoposide can be increased when it is combined with Pralsetinib.
Satralizumab-mwge Injection Satralizumab-mwge Injection The serum concentration of Etoposide can be decreased when it is combined with Satralizumab.
Progestin-Only (drospirenone) Oral Contraceptives Progestin-Only (drospirenone) Oral Contraceptives The metabolism of Drospirenone can be decreased when combined with Etoposide.
Viloxazine Viloxazine The metabolism of Etoposide can be decreased when combined with Viloxazine.
Vitamin E (Alpha-Tocopherol) Vitamin E (Alpha-Tocopherol) The metabolism of Etoposide can be increased when combined with Vitamin E.
Theophylline Theophylline The metabolism of Theophylline can be increased when combined with Etoposide.
Indomethacin Indomethacin The metabolism of Etoposide can be decreased when combined with Indomethacin.
Naproxen Naproxen The metabolism of Naproxen can be decreased when combined with Etoposide.
Trazodone Trazodone The serum concentration of Etoposide can be decreased when it is combined with Trazodone.
Hydroxyurea Hydroxyurea The risk or severity of adverse effects can be increased when Etoposide is combined with Hydroxyurea.
Floxuridine Floxuridine The risk or severity of adverse effects can be increased when Floxuridine is combined with Etoposide.
Phenobarbital Phenobarbital The metabolism of Etoposide can be increased when combined with Phenobarbital.
Methotrexate Injection Methotrexate Injection The metabolism of Etoposide can be decreased when combined with Methotrexate.
Primidone Primidone The metabolism of Etoposide can be increased when combined with Primidone.
Chlorpromazine Chlorpromazine The metabolism of Chlorpromazine can be increased when combined with Etoposide.
Diazepam Diazepam The metabolism of Diazepam can be decreased when combined with Etoposide.
Lorazepam Lorazepam The metabolism of Lorazepam can be decreased when combined with Etoposide.
Carmustine Carmustine The risk or severity of adverse effects can be increased when Carmustine is combined with Etoposide.
Bromocriptine Bromocriptine The metabolism of Etoposide can be decreased when combined with Bromocriptine.
Tranylcypromine Tranylcypromine The metabolism of Etoposide can be decreased when combined with Tranylcypromine.
Phenelzine Phenelzine The metabolism of Etoposide can be decreased when combined with Phenelzine.
Procarbazine Procarbazine The risk or severity of adverse effects can be increased when Etoposide is combined with Procarbazine.
Tetracycline Tetracycline The metabolism of Etoposide can be decreased when combined with Tetracycline.
Thioguanine Thioguanine The risk or severity of adverse effects can be increased when Tioguanine is combined with Etoposide.
Prochlorperazine Prochlorperazine The metabolism of Prochlorperazine can be decreased when combined with Etoposide.
Trifluoperazine Trifluoperazine The metabolism of Trifluoperazine can be decreased when combined with Etoposide.
Bleomycin Bleomycin The risk or severity of adverse effects can be increased when Bleomycin is combined with Etoposide.
Dapsone Dapsone The metabolism of Etoposide can be decreased when combined with Dapsone.
Oxycodone Oxycodone The metabolism of Etoposide can be decreased when combined with Oxycodone.
Methadone Methadone The metabolism of Etoposide can be increased when combined with Methadone.
Oxybutynin Oxybutynin The metabolism of Oxybutynin can be decreased when combined with Etoposide.
Maprotiline Maprotiline The metabolism of Maprotiline can be decreased when combined with Etoposide.
Orphenadrine Orphenadrine The metabolism of Etoposide can be decreased when combined with Orphenadrine.
Perphenazine Perphenazine The metabolism of Perphenazine can be decreased when combined with Etoposide.
Azathioprine Azathioprine The risk or severity of adverse effects can be increased when Etoposide is combined with Azathioprine.
Phentermine Phentermine The metabolism of Phentermine can be decreased when combined with Etoposide.
Sulfasalazine Sulfasalazine The risk or severity of adverse effects can be increased when Etoposide is combined with Sulfasalazine.
Hydrocortisone Hydrocortisone The metabolism of Etoposide can be increased when combined with Hydrocortisone.
Lomustine Lomustine The risk or severity of adverse effects can be increased when Etoposide is combined with Lomustine.
Doxorubicin Doxorubicin The metabolism of Doxorubicin can be increased when combined with Etoposide.
Cytarabine Cytarabine The risk or severity of adverse effects can be increased when Etoposide is combined with Cytarabine.
Mechlorethamine Mechlorethamine The risk or severity of adverse effects can be increased when Etoposide is combined with Mechlorethamine.
Dactinomycin Dactinomycin The risk or severity of adverse effects can be increased when Etoposide is combined with Dactinomycin.
Carbamazepine Carbamazepine The metabolism of Carbamazepine can be increased when combined with Etoposide.
Clonidine Clonidine The metabolism of Etoposide can be decreased when combined with Clonidine.
Hydralazine Hydralazine The metabolism of Etoposide can be decreased when combined with Hydralazine.
Cimetidine Cimetidine The metabolism of Etoposide can be decreased when combined with Cimetidine.
Warfarin Warfarin The therapeutic efficacy of Warfarin can be increased when used in combination with Etoposide.
Clonazepam Clonazepam The metabolism of Clonazepam can be increased when combined with Etoposide.
Loperamide Loperamide The metabolism of Loperamide can be decreased when combined with Etoposide.
Daunorubicin Daunorubicin The metabolism of Etoposide can be decreased when combined with Daunorubicin.
Griseofulvin Griseofulvin The metabolism of Etoposide can be increased when combined with Griseofulvin.
Digoxin Digoxin The serum concentration of Digoxin can be increased when it is combined with Etoposide.
Loxapine Loxapine The serum concentration of Etoposide can be increased when it is combined with Loxapine.
Chloroquine Chloroquine The metabolism of Etoposide can be decreased when combined with Chloroquine.
Quinine Quinine The serum concentration of Etoposide can be increased when it is combined with Quinine.
Calcitriol Calcitriol The metabolism of Etoposide can be increased when combined with Calcitriol.
Triamterene Triamterene The metabolism of Etoposide can be decreased when combined with Triamterene.
Sulfinpyrazone Sulfinpyrazone The metabolism of Etoposide can be increased when combined with Sulfinpyrazone.
Chlorothiazide Chlorothiazide The risk or severity of neutropenia and thrombocytopenia can be increased when Chlorothiazide is combined with Etoposide.
Isosorbide Isosorbide The metabolism of Isosorbide can be increased when combined with Etoposide.
Clindamycin Injection Clindamycin Injection The metabolism of Clindamycin can be increased when combined with Etoposide.
Secobarbital Secobarbital The metabolism of Etoposide can be increased when combined with Secobarbital.
Desipramine Desipramine The metabolism of Desipramine can be decreased when combined with Etoposide.
Amitriptyline Amitriptyline The metabolism of Etoposide can be decreased when combined with Amitriptyline.
Imipramine Imipramine The metabolism of Etoposide can be decreased when combined with Imipramine.
Probenecid Probenecid The metabolism of Etoposide can be increased when combined with Probenecid.
Quinidine Quinidine The metabolism of Etoposide can be decreased when combined with Quinidine.
Isoniazid Isoniazid The metabolism of Etoposide can be decreased when combined with Isoniazid.
Rifampin Rifampin The metabolism of Etoposide can be increased when combined with Rifampicin.
Disopyramide Disopyramide The metabolism of Etoposide can be decreased when combined with Disopyramide.
Valproic Acid Valproic Acid The metabolism of Etoposide can be decreased when combined with Valproic acid.
Tamoxifen Tamoxifen The serum concentration of Etoposide can be increased when it is combined with Tamoxifen.
Mitomycin Mitomycin The risk or severity of adverse effects can be increased when Mitomycin is combined with Etoposide.
Levothyroxine Levothyroxine The serum concentration of Etoposide can be decreased when it is combined with Levothyroxine.
Methimazole Methimazole The metabolism of Etoposide can be decreased when combined with Methimazole.
Propylthiouracil Propylthiouracil The risk or severity of adverse effects can be increased when Propylthiouracil is combined with Etoposide.
Dextromethorphan Dextromethorphan The metabolism of Etoposide can be decreased when combined with Dextromethorphan.
Cyclobenzaprine Cyclobenzaprine The metabolism of Cyclobenzaprine can be decreased when combined with Etoposide.
Niacin Niacin The metabolism of Etoposide can be decreased when combined with Niacin.
Chlorpheniramine Chlorpheniramine The metabolism of Chlorpheniramine can be decreased when combined with Etoposide.
Methyclothiazide Methyclothiazide The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Etoposide.
Hydrochlorothiazide Hydrochlorothiazide The risk or severity of neutropenia and thrombocytopenia can be increased when Hydrochlorothiazide is combined with Etoposide.
Chlorzoxazone Chlorzoxazone The metabolism of Etoposide can be decreased when combined with Chlorzoxazone.
Danazol Danazol The metabolism of Etoposide can be decreased when combined with Danazol.
Disulfiram Disulfiram The metabolism of Disulfiram can be decreased when combined with Etoposide.
Propranolol (Cardiovascular) Propranolol (Cardiovascular) The metabolism of Etoposide can be decreased when combined with Propranolol.
Nortriptyline Nortriptyline The metabolism of Nortriptyline can be increased when combined with Etoposide.
Amphotericin B Injection Amphotericin B Injection The metabolism of Etoposide can be decreased when combined with Amphotericin B.
Mercaptopurine Mercaptopurine The risk or severity of adverse effects can be increased when Etoposide is combined with Mercaptopurine.
Allopurinol Allopurinol The risk or severity of adverse effects can be increased when Allopurinol is combined with Etoposide.
Clomiphene Clomiphene The serum concentration of Clomifene can be increased when it is combined with Etoposide.
Fluorouracil Injection Fluorouracil Injection The risk or severity of adverse effects can be increased when Fluorouracil is combined with Etoposide.
Colchicine Colchicine The metabolism of Colchicine can be decreased when combined with Etoposide.
Cephalexin Cephalexin The metabolism of Cephalexin can be decreased when combined with Etoposide.
Dacarbazine Dacarbazine The risk or severity of adverse effects can be increased when Etoposide is combined with Dacarbazine.
Acetazolamide Acetazolamide The metabolism of Etoposide can be decreased when combined with Acetazolamide.
Bacillus Calmette-Guerin (BCG) Vaccine Bacillus Calmette-Guerin (BCG) Vaccine The risk or severity of infection can be increased when Bacillus calmette-guerin substrain tice live antigen is combined with Etoposide.
Ketoconazole Ketoconazole The serum concentration of Etoposide can be increased when it is combined with Ketoconazole.
Thiotepa Injection Thiotepa Injection The metabolism of Thiotepa can be increased when combined with Etoposide.
Vincristine Injection Vincristine Injection The metabolism of Vincristine can be increased when combined with Etoposide.
Dipyridamole Dipyridamole The risk or severity of bleeding can be increased when Dipyridamole is combined with Etoposide.
Vinblastine Vinblastine The metabolism of Etoposide can be increased when combined with Vinblastine.
Metoprolol Metoprolol The metabolism of Metoprolol can be decreased when combined with Etoposide.
Hydroxyzine Hydroxyzine The metabolism of Etoposide can be decreased when combined with Hydroxyzine.
Thiothixene Thiothixene The metabolism of Thiothixene can be decreased when combined with Etoposide.
Aspirin Aspirin The risk or severity of bleeding can be increased when Acetylsalicylic acid is combined with Etoposide.
Chlorambucil Chlorambucil The risk or severity of adverse effects can be increased when Chlorambucil is combined with Etoposide.
Alprazolam Alprazolam The metabolism of Alprazolam can be decreased when combined with Etoposide.
Triazolam Triazolam The metabolism of Triazolam can be decreased when combined with Etoposide.
Diltiazem Diltiazem The metabolism of Etoposide can be decreased when combined with Diltiazem.
Nifedipine Nifedipine The metabolism of Etoposide can be increased when combined with Nifedipine.
Verapamil Verapamil The serum concentration of Etoposide can be increased when it is combined with Verapamil.
Cisplatin Injection Cisplatin Injection The risk or severity of adverse effects can be increased when Cisplatin is combined with Etoposide.
Streptozocin Streptozocin The risk or severity of adverse effects can be increased when Streptozocin is combined with Etoposide.
Glyburide Glyburide The metabolism of Glyburide can be decreased when combined with Etoposide.
Dicloxacillin Dicloxacillin The metabolism of Etoposide can be increased when combined with Dicloxacillin.
Nafcillin Injection Nafcillin Injection The metabolism of Etoposide can be increased when combined with Nafcillin.
Pentoxifylline Pentoxifylline The metabolism of Pentoxifylline can be decreased when combined with Etoposide.
Pentamidine Injection Pentamidine Injection The metabolism of Etoposide can be decreased when combined with Pentamidine.
Gemfibrozil Gemfibrozil The metabolism of Etoposide can be decreased when combined with Gemfibrozil.
Guanabenz Guanabenz The metabolism of Etoposide can be decreased when combined with Guanabenz.
Pimozide Pimozide The metabolism of Pimozide can be increased when combined with Etoposide.
Flurbiprofen Flurbiprofen The metabolism of Etoposide can be decreased when combined with Flurbiprofen.
Amiodarone Amiodarone The metabolism of Amiodarone can be increased when combined with Etoposide.
Buspirone Buspirone The metabolism of Etoposide can be decreased when combined with Buspirone.
Lovastatin Lovastatin The metabolism of Lovastatin can be decreased when combined with Etoposide.
Ciprofloxacin Ciprofloxacin The metabolism of Etoposide can be decreased when combined with Ciprofloxacin.
Diclofenac Diclofenac The metabolism of Etoposide can be decreased when combined with Diclofenac.
Fluoxetine Fluoxetine The metabolism of Etoposide can be decreased when combined with Fluoxetine.
Interferon Alfa-2b Injection Interferon Alfa-2b Injection The risk or severity of adverse effects can be increased when Interferon alfa-2b is combined with Etoposide.
Clozapine Clozapine The risk or severity of neutropenia can be increased when Etoposide is combined with Clozapine.
Idarubicin Idarubicin The risk or severity of adverse effects can be increased when Etoposide is combined with Idarubicin.
Ofloxacin Ofloxacin The metabolism of Etoposide can be decreased when combined with Ofloxacin.
Fludarabine Injection Fludarabine Injection The risk or severity of adverse effects can be increased when Etoposide is combined with Fludarabine.
Pentostatin Injection Pentostatin Injection The risk or severity of adverse effects can be increased when Pentostatin is combined with Etoposide.
Clarithromycin Clarithromycin The serum concentration of Etoposide can be increased when it is combined with Clarithromycin.
Felodipine Felodipine The metabolism of Felodipine can be decreased when combined with Etoposide.
Nabumetone Nabumetone The metabolism of Etoposide can be decreased when combined with Nabumetone.
Pravastatin Pravastatin Pravastatin may decrease the excretion rate of Etoposide which could result in a higher serum level.
Simvastatin Simvastatin The serum concentration of Etoposide can be increased when it is combined with Simvastatin.
Epoetin Alfa, Injection Epoetin Alfa, Injection The risk or severity of Thrombosis can be increased when Erythropoietin is combined with Etoposide.
Amlodipine Amlodipine The metabolism of Amlodipine can be increased when combined with Etoposide.
Teniposide Injection Teniposide Injection The metabolism of Etoposide can be increased when combined with Teniposide.
Itraconazole Itraconazole The serum concentration of Etoposide can be increased when it is combined with Itraconazole.
Atovaquone Atovaquone The serum concentration of Etoposide can be increased when it is combined with Atovaquone.
Rifabutin Rifabutin The metabolism of Etoposide can be increased when combined with Rifabutin.
Bisoprolol Bisoprolol The serum concentration of Bisoprolol can be increased when it is combined with Etoposide.
Zolpidem Zolpidem The metabolism of Zolpidem can be increased when combined with Etoposide.
Doxazosin Doxazosin The metabolism of Doxazosin can be decreased when combined with Etoposide.
Isradipine Isradipine The metabolism of Etoposide can be decreased when combined with Isradipine.
Omeprazole Omeprazole The metabolism of Etoposide can be increased when combined with Omeprazole.
Cisapride Cisapride The metabolism of Etoposide can be decreased when combined with Cisapride.
Fluvastatin Fluvastatin The metabolism of Fluvastatin can be decreased when combined with Etoposide.
Venlafaxine Venlafaxine Venlafaxine may increase the excretion rate of Etoposide which could result in a lower serum level and potentially a reduction in efficacy.
Famciclovir Famciclovir The metabolism of Famciclovir can be decreased when combined with Etoposide.
Fluvoxamine Fluvoxamine The metabolism of Etoposide can be decreased when combined with Fluvoxamine.
Nefazodone Nefazodone The metabolism of Etoposide can be decreased when combined with Nefazodone.
Lamotrigine Lamotrigine The metabolism of Etoposide can be increased when combined with Lamotrigine.
Losartan Losartan The metabolism of Etoposide can be decreased when combined with Losartan.
Tramadol Tramadol The metabolism of Tramadol can be decreased when combined with Etoposide.
Vinorelbine Injection Vinorelbine Injection The metabolism of Etoposide can be increased when combined with Vinorelbine.
Carboplatin Injection Carboplatin Injection The risk or severity of adverse effects can be increased when Etoposide is combined with Carboplatin.
Lansoprazole Lansoprazole The metabolism of Etoposide can be increased when combined with Lansoprazole.
Ifosfamide Injection Ifosfamide Injection The metabolism of Ifosfamide can be increased when combined with Etoposide.
Pegaspargase Injection Pegaspargase Injection The risk or severity of adverse effects can be increased when Pegaspargase is combined with Etoposide.
Nicardipine Nicardipine The metabolism of Etoposide can be decreased when combined with Nicardipine.
Ticlopidine Ticlopidine The metabolism of Etoposide can be decreased when combined with Ticlopidine.
Saquinavir Saquinavir The serum concentration of Etoposide can be increased when it is combined with Saquinavir.
Dalteparin Injection Dalteparin Injection The risk or severity of bleeding can be increased when Dalteparin is combined with Etoposide.
Nisoldipine Nisoldipine The metabolism of Etoposide can be decreased when combined with Nisoldipine.
Riluzole Riluzole The metabolism of Etoposide can be decreased when combined with Riluzole.
Anastrozole Anastrozole The risk or severity of cardiotoxicity can be increased when Etoposide is combined with Anastrozole.
Gemcitabine Injection Gemcitabine Injection The risk or severity of adverse effects can be increased when Gemcitabine is combined with Etoposide.
Indinavir Indinavir The metabolism of Etoposide can be decreased when combined with Indinavir.
Ritonavir Ritonavir The serum concentration of Etoposide can be increased when it is combined with Ritonavir.
Docetaxel Injection Docetaxel Injection The metabolism of Docetaxel can be increased when combined with Etoposide.
Clomipramine Clomipramine The metabolism of Clomipramine can be increased when combined with Etoposide.
Zafirlukast Zafirlukast The metabolism of Etoposide can be decreased when combined with Zafirlukast.
Mirtazapine Mirtazapine The metabolism of Etoposide can be decreased when combined with Mirtazapine.
Topiramate Topiramate The metabolism of Etoposide can be increased when combined with Topiramate.
Zileuton Zileuton The metabolism of Etoposide can be decreased when combined with Zileuton.
Insulin Lispro Injection Insulin Lispro Injection The metabolism of Etoposide can be increased when combined with Insulin lispro.
Nelfinavir Nelfinavir The metabolism of Etoposide can be decreased when combined with Nelfinavir.
Fexofenadine Fexofenadine The serum concentration of Fexofenadine can be increased when it is combined with Etoposide.
Azithromycin Azithromycin The metabolism of Azithromycin can be decreased when combined with Etoposide.
Carvedilol Carvedilol The serum concentration of Etoposide can be increased when it is combined with Carvedilol.
Flutamide Flutamide The metabolism of Etoposide can be decreased when combined with Flutamide.
Selegiline Selegiline The metabolism of Etoposide can be decreased when combined with Selegiline.
Bicalutamide Bicalutamide The metabolism of Etoposide can be decreased when combined with Bicalutamide.
Propafenone Propafenone The serum concentration of Etoposide can be increased when it is combined with Propafenone.
Raloxifene Raloxifene The metabolism of Etoposide can be decreased when combined with Raloxifene.
Irbesartan Irbesartan The metabolism of Etoposide can be decreased when combined with Irbesartan.
Finasteride Finasteride The metabolism of Finasteride can be decreased when combined with Etoposide.
Quetiapine Quetiapine The metabolism of Quetiapine can be decreased when combined with Etoposide.
Paroxetine Paroxetine The metabolism of Etoposide can be decreased when combined with Paroxetine.
Citalopram Citalopram The metabolism of Etoposide can be decreased when combined with Citalopram.
Capecitabine Capecitabine The risk or severity of adverse effects can be increased when Etoposide is combined with Capecitabine.
Efavirenz Efavirenz The metabolism of Etoposide can be increased when combined with Efavirenz.
Sildenafil Sildenafil The serum concentration of Etoposide can be increased when it is combined with Sildenafil.
Trastuzumab Injection Trastuzumab Injection Trastuzumab may increase the neutropenic activities of Etoposide.
Rosiglitazone Rosiglitazone The metabolism of Rosiglitazone can be decreased when combined with Etoposide.
Thalidomide Thalidomide The risk or severity of adverse effects can be increased when Etoposide is combined with Thalidomide.
Nateglinide Nateglinide The metabolism of Etoposide can be decreased when combined with Nateglinide.
Rabeprazole Rabeprazole The metabolism of Etoposide can be decreased when combined with Rabeprazole.
Terbinafine Terbinafine The metabolism of Terbinafine can be increased when combined with Etoposide.

Content provided by: AHFS® Patient Medication Information™. © Copyright, 2021. The American Society of Health-System Pharmacists

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