Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Broccoli Non-Alcohol Ingredients & Drug Interactions

by Hawaii Pharm

Broccoli Non-Alcohol label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Broccoli Non-Alcohol against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Broccoli Non-Alcohol is a dietary supplement by Hawaii Pharm with 1 active ingredient. Its ingredients are commonly taken for general nutrition and antioxidant support, heart and digestive health, detoxification support.Based on those ingredients, 187 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are certified organic Broccoli extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Broccoli Non-Alcohol by Hawaii Pharm

Ask about any prescription or over-the-counter medication and we check it for interactions with Broccoli Non-Alcohol by Hawaii Pharm — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Broccoli Non-Alcohol by Hawaii Pharm

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 1 active ingredient.

This product contains one active ingredient: certified organic broccoli extract in a non-alcoholic liquid form. Broccoli is a cruciferous vegetable, and the extract concentrates its bioactive compounds—mainly glucosinolates—that are responsible for both its potential health effects and its interaction with certain medications.

The inactive ingredients are vegetable palm glycerin (a sweetener and solvent) and crystal clear artesian Hawaiian water.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Broccoli's overall clinical evidence instead.

Moderate

Some clinical evidence supports Broccoli for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Colorectal cancer — rated "Possibly Effective" (Natural Medicines).

The evidence for broccoli extract is mixed. It's rated Possibly Effective for reducing colorectal cancer risk based on available research.

For bladder cancer, breast cancer, fibromyalgia, and gastric cancer, the evidence isn't established well enough for us to rate it one way or the other. If you're considering this for a specific health goal, talk it over with your doctor to see whether the evidence supports it for your situation.

The evidence, ingredient by ingredient Broccoli

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Broccoli as a food is generally well tolerated and safe in normal amounts. However, concentrated supplements like this extract are much less studied.

The safety data advises caution with concentrated extracts unless your doctor approves. Side effects reported from broccoli seed and sprout extracts include loose stools, diarrhea, abdominal pain, and abdominal cramping—especially at higher doses.

Topically, allergic contact reactions have occurred. Pregnancy and lactation safety is rated Likely Safe, though concentrated extracts haven't been extensively studied in these populations.

Side effects, ingredient by ingredient Broccoli

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Broccoli.
  • The most serious interaction on file is rated Moderate.
  • For scale: 187 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you're on any drugs metabolized by CYP1A2 or CYP2A6 enzymes. These are Moderate-severity interactions that could lower your medication's effectiveness.

The interaction checker on this page can help you look up your specific drugs.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

If you're interested in broccoli's potential benefits and your doctor gives the okay, this extract is worth considering—but only after checking it against your current medications with your pharmacist or doctor. The enzyme-boosting effect is real and can reduce how well some drugs work.

Anyone taking medications processed by the liver should be especially careful.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 26, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Broccoli Non-Alcohol, straight from the product label.

Brand Hawaii Pharm
Barcode (UPC) 6339127899636
Net contents 4 Fluid Ounce(s); 120 mL
Market status On market
Date entered into DSLD Dec 26, 2020
DSLD ID 238644
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating), Organic, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Broccoli Non-Alcohol by Hawaii Pharm, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
20 Drop(s)
Maximum serving Sizes:
30 Drop(s)
UPC/BARCODE
6339127899636
IngredientAmount% DV
certified organic Broccoli extract0 NP--

Other ingredients: Vegetable Palm Glycerin, crystal clear artesian Hawaiian Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Hawaii Pharm Non-Alcohol Herbal Extract Highest quality since 2008

Made with Aloha!

Formulation

Contains no gluten, artificial colors, pesticides, preservatives, heavy metals. Non GMO.

Super concentrated liquid herbal extract Dry herb/menstruum ratio: 1:3

Contains no alcohol

Description: We meticulously produced this extract according to precise standards where each herbs are individually extracted according to their distinct characteristic to ensure a broad spectrum of therapeutic plant compounds. We use a classic maceration extraction method in combination with ultrasonic extraction, so that the vitamins, minerals, alkaloids, flavonoids and other active constituents of the herbs are maintained.

Non GMO Gluten free

Manufactured in an FDA registered facility. Ultra Sonic

Made in USA, Hawaii

Suggested/Recommended/Usage/Directions

Directions for use: Shake well before using. Take about 20-30 drops in juice, water, tea or as desired up to four times per day.

Precautions

Warnings: Keep out of the reach of children.

Not to be used during pregnancy.

Do not use if you are allergic to any ingredients.

Consult a physician before uisng if nursing or taking any medications.

Do not use if seal is broken or missing.

Storage

Refrigerate after opening.

Formula

(Brassica oleracea)

FDA Statement of Identity

Herbal Dietary Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

FDA Registered Facility Made in United States of America USA

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Broccoli Non-Alcohol by Hawaii Pharm label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Broccoli Non-Alcohol label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Broccoli Non-Alcohol by Hawaii Pharm

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size20 Drop(s) Dosage formLiquid Amounts shown are per serving.

Certified organic Broccoli extract

Interacts with
187 drugs
0 NP per serving

Broccoli is a nutritious cruciferous vegetable rich in fiber, vitamins, and plant compounds like sulforaphane that have drawn scientific interest for...

Certified organic Broccoli extract monograph & interactions

Other (inactive) ingredients: Vegetable Palm Glycerin, Crystal clear artesian Hawaiian Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Broccoli Non-Alcohol by Hawaii Pharm Drug Interactions

Want to check YOUR meds against Broccoli Non-Alcohol?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
187Drugs
187 Moderate

Ingredients driving the most interactions

certified organic Broccoli extract 187

Individual Drug Interactions

The ingredients in Broccoli Non-Alcohol interact with 187 drugs. Click any drug to see the details.

1 of the 1 ingredient in Broccoli Non-Alcohol interact with drugs. Each result below shows which ingredient is responsible. certified organic Broccoli extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Broccoli Non-Alcohol with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

certified organic Broccoli extract2 drug types · 187 drugs

Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP1A2.
Pharmacokinetic research in humans shows that eating 500 grams of fresh broccoli daily for 6-12 days can increase CYP1A2 activity by 10% to 200%. Induction of CYP1A2 activity by broccoli is attributed to its glucosinolate constituents.

Likelihood Possible Evidence B
Cytochrome P450 2A6 (Cyp2A6) Substrates

Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP2A6.
Pharmacokinetic research in humans shows that eating 500 grams of broccoli daily for 6 days increases CYP2A6 activity by 135% to 550%. Induction of CYP2A6 activity is attributed to its glucosinolate constituents.

Likelihood Possible Evidence B
certified organic Broccoli extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Broccoli Non-Alcohol, from the product label.

Hawaii Pharm

See all Hawaii Pharm products
Name
Hawaii Pharm LLC
City
Honolulu
State
HI
ZipCode
96815
Pharmacist Counseling Corner

Broccoli Non-Alcohol by Hawaii Pharm: Common Questions

Does Broccoli Non-Alcohol by Hawaii Pharm interact with any medications?
Yes. Based on its ingredients, Broccoli Non-Alcohol has a known interaction with 187 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Broccoli Non-Alcohol contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe to take while pregnant or breastfeeding?
Broccoli itself in pregnancy and lactation is rated Likely Safe. That said, concentrated extracts like this one haven't been studied as thoroughly as the whole food. Talk with your doctor or midwife before starting any supplement during pregnancy or while nursing to make sure it's right for your situation.
Can I take this if I'm on blood pressure or heart medications?
That depends on which specific medication you're taking, because some are broken down by the liver enzymes this broccoli extract affects. Check your exact medication name in the interaction checker on this page, or ask your pharmacist or doctor before starting.
What's the difference between eating broccoli and taking this extract?
This is a concentrated liquid extract, so the active compounds are much more potent than you'd get from eating fresh broccoli. That means the enzyme-boosting effect on your liver could be stronger, which is why the interaction risk matters more here.
Does this really help prevent cancer?
Research suggests broccoli may be Possibly Effective for colorectal cancer risk. For other cancers like breast, bladder, and stomach cancer, we don't have enough reliable evidence yet to say either way. Always talk with your doctor about cancer prevention strategies that fit your individual risk.
What side effects should I watch for?
The most common ones are loose stools, diarrhea, belly pain, and cramping—especially if you take higher doses. Allergic skin reactions to broccoli have also been reported. If you develop any of these, stop taking it and let your pharmacist or doctor know.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Broccoli Non-Alcohol is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Broccoli Non-Alcohol label
Go deeper

The Full Monographs Behind Broccoli Non-Alcohol’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Broccoli

Interacts with 187 drugs

Broccoli is a nutritious cruciferous vegetable rich in fiber, vitamins, and plant compounds like sulforaphane that have drawn scientific interest for health benefits. Eating broccoli as food...

Read the full Broccoli monograph →
Sources

Sources & How We Checked

Broccoli Non-Alcohol's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Broccoli 5 references
  1. Kristal AR, Lampe JW. Brassica vegetables and prostate cancer risk: a review of the epidemiological evidence. Nutr Cancer 2002;42:1-9. PubMed
  2. Chakrabarti A, Prais L, Foulds IS. Allergic contact dermatitis to broccoli. Br J Dermatol 2003;148:172-3. PubMed
  3. Hakooz, N. and Hamdan, I. Effects of dietary broccoli on human in vivo caffeine metabolism: a pilot study on a group of Jordanian volunteers. Curr Drug Metab 2007;8(1):9-15. PubMed
  4. Kall MA, Vang O, Clausen J. Effects of dietary broccoli on human drug metabolising activity. Cancer Lett. 1997;114(1-2):169-70. PubMed
  5. Bauman JE, Hsu CH, Centuori S, et al. Randomized Crossover Trial Evaluating Detoxification of Tobacco Carcinogens by Broccoli Seed and Sprout Extract in Current Smokers. Cancers (Basel). 2022;14(9):2129. Published 2022 Apr 24. PubMed

See these in context on the Broccoli monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team