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Dietary supplement

Calm24 Ingredients & Drug Interactions

by Nattura

Calm24 label
See full label image
Softgel Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Calm24 against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Calm24 is a dietary supplement by Nattura with 1 active ingredient. Its ingredients are commonly taken for anxiety and stress, sleep problems, relaxation and calming.Based on those ingredients, 248 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lavender Oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Calm24 by Nattura

Ask about any prescription or over-the-counter medication and we check it for interactions with Calm24 by Nattura — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Calm24 by Nattura

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Calm24 contains one active ingredient: lavender oil. Lavender is an herb whose oil has been studied for its potential calming effects.

The softgel also contains inactive ingredients — gelatin, glycerin, and purified water — that form the capsule and help deliver the oil.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Lavender's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: relaxation and stress relief.
  • We looked for evidence on: Stress, Perioperative anxiety, Pre-procedural anxiety, Insomnia, Psychological well-being, anxiety — and 2 related terms.
  • The closest evidence on file: Lavender is rated "Insufficient Reliable Evidence To Rate" for Pre-procedural anxiety (Natural Medicines).
  • Also on file: Lavender is rated "Insufficient Reliable Evidence To Rate" for Insomnia, Stress, Psychological well-being, Perioperative anxiety.

The evidence for lavender oil's effectiveness varies by condition. For period pain (dysmenorrhea), it's possibly effective.

For cancer-related pain, it's rated possibly ineffective. For hair loss (alopecia areata), pre-procedure anxiety, and cancer-related fatigue, there isn't enough reliable evidence to rate how well it works.

The data on file doesn't support claims about other uses.

The evidence, ingredient by ingredient Lavender

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lavender oil in this oral form is generally well tolerated. The most common side effects are mild — breath odor, constipation, diarrhea, heartburn, burping, headache, and nausea.

Rare cases of a skin reaction called allergic contact dermatitis have been reported, and there are isolated reports of gynecomastia (breast enlargement) in young boys exposed to lavender oil. Because long-term safety data is limited, use only under your healthcare provider's guidance and avoid medicinal amounts without approval.

Side effects, ingredient by ingredient Lavender

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Lavender.
  • The most serious interaction on file is rated Moderate.
  • For scale: 248 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Calm24, check any CNS depressants you're on — that includes sedatives, sleep aids, anti-anxiety medications, and narcotic painkillers. Lavender oil may increase both the therapeutic and unwanted sedating effects of these drugs.

Use the medication checker below to verify your specific prescriptions and over-the-counter products.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Calm24 is a single-ingredient lavender supplement that may help with period pain and has a good tolerability profile at standard doses. If you're taking any sedating medications — sleeping pills, anti-anxiety drugs, pain relievers, or even over-the-counter sleep aids — check with your pharmacist first, since lavender can amplify their drowsy effects.

Talk to us before starting if you have any questions about how it fits with your current medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Calm24, straight from the product label.

Brand Nattura
Net contents 60 Softgel(s)
Market status On market
Date entered into DSLD Aug 22, 2024
DSLD ID 318257
Product type Botanical
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Calm24 by Nattura, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
60
IngredientAmount% DV
Lavender Oil500 mg--

Other ingredients: Gelatin, Glycerin, Water, Purified

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

100% natural

Helps reduce tension & stress

Non-GMO

Manufacturer's Integrated Management System Certified by TUV Thuringen e.V. Melchendorfer Str. 64, 99096 Erfurt, Germany

Suggested/Recommended/Usage/Directions

Directions: As a food supplement take one (1) softgel once or twice daily after meal or as directed by your healthcare professional.

Precautions

Warning: Do not exceed recommended dose. Discontinue use and consult your healthcare practitioner if any adverse reactions occur. Do not use if outer bottle seal is missing or damaged.

If you are pregnant, nursing, taking any medication or have a medical condition, please consult your healthcare practitioner before taking any food supplement.

Keep out of the reach of children.

Food supplements should not be used as a substitute for a varied and balanced diet and healthy lifestyle.

Storage

Store in a cool, dry place.

Formula

Lavender oil Cold macerated 500mg

FDA Statement of Identity

Food Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Calm24 by Nattura label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Calm24 label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Calm24 by Nattura

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container60 Amounts shown are per serving.

Lavender Oil

Interacts with
248 drugs
500 mg per serving Form: Lavandula officinalis Oil

Lavender is a fragrant herb most popular for promoting relaxation, easing anxiety, and supporting sleep, with some encouraging evidence for a standard...

Lavender Oil monograph & interactions

Other (inactive) ingredients: Gelatin, Glycerin, Water, Purified. These complete the product’s ingredient list but are not active constituents.

Interaction report

Calm24 by Nattura Drug Interactions

Want to check YOUR meds against Calm24?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
248Drugs
248 Moderate

Ingredients driving the most interactions

Lavender Oil 248

Individual Drug Interactions

The ingredients in Calm24 interact with 248 drugs. Click any drug to see the details.

1 of the 1 ingredient in Calm24 interact with drugs. Each result below shows which ingredient is responsible. Lavender Oil

Each ingredient & the kinds of drugs it affects

For each ingredient in Calm24 with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Lavender Oil1 drug type · 248 drugs

Cns Depressants

Theoretically, lavender might potentiate the therapeutic effects and adverse effects of CNS depressants.
Laboratory research suggests that lavender has sedative effects. However, clinical studies in patients taking oral lavender oil (Silexan) 160 mg for 10 weeks or taking lavender flower powder 1 gram daily for 2 months have not reported side effects of drowsiness, sedation, or sleepiness. There is still some concern that higher doses or different preparations of lavender might have additive effects with CNS depressant medications.

Likelihood Unlikely Evidence D
Lavender Oil full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Calm24, from the product label.

Nattura

See all Nattura products
Name
iCapital LLC
Street Address
Hangar 5, Hurricane Way North Weald Airfield
City
Essex
ZipCode
CM16 6AA
Web Address
www.SupremeVitamin.com
Pharmacist Counseling Corner

Calm24 by Nattura: Common Questions

Does Calm24 by Nattura interact with any medications?
Yes. Based on its ingredients, Calm24 has a known interaction with 248 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Calm24 contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is lavender oil, and what is it supposed to do?
Lavender oil is derived from the lavender plant. Laboratory research suggests it has sedative properties, and in people it's been studied for calming effects during anxiety and for period pain. The evidence is strongest for period pain, where it's rated possibly effective.
What are the most common side effects I might notice?
The most common are mild: breath odor, constipation, diarrhea, heartburn, burping, headache, and nausea. Serious side effects are rare, though allergic skin reactions and a rare case of breast enlargement in young boys have been reported.
Is lavender oil safe to use if I'm pregnant or breastfeeding?
There isn't enough reliable safety data to know either way. If you're pregnant or breastfeeding, talk with your doctor or pharmacist about whether Calm24 is right for you.
Can I take this if I'm already taking a sleeping pill or anxiety medication?
You should check with your pharmacist first. Lavender may strengthen the sedating effects of these drugs, which could mean extra drowsiness or dizziness. Use the medication checker on this page to look up your specific medications.
Does this product have any fillers?
The capsule itself is made of gelatin, glycerin, and purified water — these are the inactive ingredients that form and fill the softgel. Lavender oil is the only active ingredient.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Calm24 label
Go deeper

The Full Monographs Behind Calm24’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lavender

Interacts with 248 drugs

Lavender is a fragrant herb most popular for promoting relaxation, easing anxiety, and supporting sleep, with some encouraging evidence for a standardized oral lavender oil product for anxie...

Read the full Lavender monograph →
Sources

Sources & How We Checked

Calm24's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 20 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lavender 20 references
  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Schulz V, Hansel R, Tyler VE. Rational Phytotherapy: A Physician's Guide to Herbal Medicine. Terry C. Telger, transl. 3rd ed. Berlin, GER: Springer, 1998.
  3. Akhondzadeh S, Kashani L, Fotouhi A, et al. Comparison of Lavandula angustifolia Mill. tincture and imipramine in the treatment of mild to moderate depression: a double-blind, randomized trial. Prog Neuropsychopharmacol Biol Psychiatry 2003;27:123-7. PubMed
  4. Varma S, Blackford S, Statham BN, Blackwell A. Combined contact allergy to tea tree oil and lavender oil complicating chronic vulvovaginitis. Contact Dermatitis 2000;42:309-10.
  5. Coulson IH and Khan AS. Facial 'pillow' dermatitis due to lavender oil allergy. Contact Dermatitis 1999;41(2):111. PubMed
  6. Woelk, H. and Schlafke, S. A multi-center, double-blind, randomised study of the Lavender oil preparation Silexan in comparison to Lorazepam for generalized anxiety disorder. Phytomedicine. 2010;17(2):94-99. PubMed
  7. Kasper, S., Gastpar, M., Muller, W. E., Volz, H. P., Moller, H. J., Dienel, A., and Schlafke, S. Silexan, an orally administered Lavandula oil preparation, is effective in the treatment of 'subsyndromal' anxiety disorder: a randomized, double-blind, plac
  8. Uehleke, B., Schaper, S., Dienel, A., Schlaefke, S., and Stange, R. Phase II trial on the effects of Silexan in patients with neurasthenia, post-traumatic stress disorder or somatization disorder. Phytomedicine. 6-15-2012;19(8-9):665-671. PubMed
  9. Brandao FM. Occupational allergy to lavender oil. Contact Dermatitis 1986;15(4):249-250. PubMed
  10. Rademaker M. Allergic contact dermatitis from lavender fragrance in Difflam gel. Contact Dermatitis 1994;31(1):58-59. PubMed
  11. Kasper S, Gastpar M, Müller WE, et al. Lavender oil preparation Silexan is effective in generalized anxiety disorder--a randomized, double-blind comparison to placebo and paroxetine. Int J Neuropsychopharmacol. 2014 Jun;17(6):859-69. PubMed
  12. Farshbaf-Khalili A, Kamalifard M, Namadian M. Comparison of the effect of lavender and bitter orange on anxiety in postmenopausal women: A triple-blind, randomized, controlled clinical trial. Complement Ther Clin Pract 2018;31:132-8. PubMed
  13. Bingham LJ, Tam MM, Palmer AM, Cahill JL, Nixon RL. Contact allergy and allergic contact dermatitis caused by lavender: A retrospective study from an Australian clinic. Contact Dermatitis. 2019;81(1):37-42. PubMed
  14. Donelli D, Antonelli M, Bellinazzi C, Gensini GF, Firenzuoli F. Effects of lavender on anxiety: A systematic review and meta-analysis. Phytomedicine. 2019;65:153099. PubMed
  15. Firoozeei TS, Feizi A, Rezaeizadeh H, Zargaran A, Roohafza HR, Karimi M. The antidepressant effects of lavender (Lavandula angustifolia Mill.): A systematic review and meta-analysis of randomized controlled clinical trials. Complement Ther Med 2021;59:102 PubMed
  16. Kodama T, Watanabe T, Mataki N, Kanoh S, Kichikawa Y. Acute eosinophilic pneumonia following aromatherapy with essential oil. Respir Med Case Rep 2022;37:101657. PubMed
  17. Barbaud A, Kurihara F, Raison-Peyron N, et al. Allergic contact dermatitis from essential oil in consumer products: Mode of uses and value of patch-tests with an essential oil series. Results of a French study of the DAG (dermato-allergy group of the Fren
  18. Ozer H, Sayan ZA, Baloglu I, Ozturk Y, Yonet F, Turkmen K. Unknown criminals for kidney: Acute interstitial nephritis due to lavender tea. Explore (NY) 2023. PubMed
  19. Kasper S, Volz HP, Möller HJ, et al. Lavender oil preparation Silexan is effective in mild-to-moderate major depression: a randomized, placebo- and reference-controlled trial. Eur Arch Psychiatry Clin Neurosci 2024. PubMed
  20. Simaei SR, Askari VR, Rostami M, et al. Lavender and metformin effectively propagate progesterone levels in patients with polycystic ovary syndrome: A randomized, double-blind clinical trial. Fitoterapia 2023;172:105720. PubMed

See these in context on the Lavender monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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