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Dietary supplement

Cherry Fruit Extract Ingredients & Drug Interactions

by Bluebonnet

Capsule Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Cherry Fruit Extract is a dietary supplement by Bluebonnet with 3 active ingredients. Its ingredients are commonly taken for muscle soreness after exercise, gout and joint discomfort, sleep support.Based on those ingredients, 643 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Black Cherry Fruit Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Cherry Fruit Extract by Bluebonnet

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 3 active ingredients.
  • “Cherry Fruit Extract Blend” is a proprietary blend — the label gives one combined amount (1,000 mg) without saying how much of each component you get.

This supplement contains three active cherry fruit extracts: tart cherry, black cherry, and sweet cherry. Together they're designed to deliver the compounds found in whole cherries in concentrated form.

The product also contains inactive ingredients—cellulose, hypromellose, purified water, magnesium stearate, and silicon dioxide—which are standard capsule materials and binders.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: free radical protection and joint health.
  • We looked for evidence on: Exercise-induced muscle soreness, Gout, Osteoarthritis, Range of motion, Rheumatoid arthritis, General inflammation.
  • The closest evidence on file: Sour Cherry is rated "Insufficient Reliable Evidence To Rate" for Exercise-induced muscle soreness (Natural Medicines).
  • Also on file: Sour Cherry is rated "Insufficient Reliable Evidence To Rate" for Osteoarthritis, Gout, Range of motion.
  • Also on file: Sweet Cherry is rated "Insufficient Reliable Evidence To Rate" for Osteoarthritis, Gout.

The evidence is mixed and often limited. Tart cherry is possibly effective for athletic performance, but the data for exercise-induced muscle soreness, respiratory infections, cognitive function, ADHD, and fibromyalgia falls short—we don't have reliable evidence to rate it for those.

Sweet cherry's evidence for cardiovascular disease, diabetes, obesity, and osteoarthritis is also insufficient to rate. Black cherry has no established effectiveness ratings in our data.

If you're considering this for a specific condition, chat with your doctor or pharmacist about what the current evidence actually supports.

The evidence, ingredient by ingredient Sour Cherry Wild Cherry Sweet Cherry

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Tart cherry and sweet cherry are generally well tolerated when eaten as whole fruit or juice. In concentrated supplement form, they're less studied, so caution is wise.

The most common side effects from tart cherry are mild—abdominal pain, loose stools, and general gastrointestinal upset—and occur in a small number of people. Sweet cherry can trigger allergic reactions in sensitive individuals, ranging from mouth irritation to hives, swelling, difficulty breathing, or stomach symptoms.

Black cherry is the ingredient requiring the most caution. Large amounts can cause cyanide toxicity, which is serious.

The product contains only a concentrated extract in a capsule, not whole fruit, so the risk is lower than consuming hundreds of grams of raw cherries—but the safety data for concentrated black cherry supplements is limited. Black cherry should be avoided during pregnancy and breastfeeding.

Tart cherry and sweet cherry are likely safe in pregnancy and lactation, though concentrated supplement safety hasn't been fully studied.

Side effects, ingredient by ingredient Sour Cherry Wild Cherry Sweet Cherry

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 3 matched ingredients can interact with medications — Wild Cherry.
  • The most serious interaction on file is rated Moderate.
  • For scale: 644 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your doctor or pharmacist if you take any medications metabolized by the liver enzyme CYP3A4. This includes (but is not limited to) lovastatin, ketoconazole, itraconazole, and many other common drugs.

The black cherry extract in this product may inhibit that enzyme and raise drug levels, though this hasn't yet been seen in real patients. No interactions are documented for tart cherry or sweet cherry, but confirm your full medication list is clear before you begin.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This product may appeal to you if you're interested in cherry's potential benefits for athletic recovery or general wellness, and you don't take medications metabolized by CYP3A4 (which is a large group). The biggest caution is black cherry's interaction with that enzyme system and its limited safety profile in concentrated form.

If you take any prescription medications, check with your doctor or pharmacist before you start—especially if you're pregnant, breastfeeding, or take cholesterol, antifungal, or immunosuppressant drugs.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Cherry Fruit Extract, straight from the product label.

Brand Bluebonnet
Barcode (UPC) 743715009806
Net contents 60 Vegetable Capsule(s)
Market status On market
Date entered into DSLD Jul 25, 2024
DSLD ID 315006
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, No Allergies, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Cherry Fruit Extract by Bluebonnet, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
30
UPC/BARCODE
743715009806
IngredientAmount% DV
Tart Cherry Fruit Extract0 NP--
Black Cherry Fruit Extract0 NP--
Sweet Cherry Fruit Extract0 NP--
Cherry Fruit Extract Blend1000 mg--

Other ingredients: Cellulose, Hypromellose, Water, Purified, Magnesium Stearate, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Bluebonnet's Cherry Fruit Extract Vegetable Capsules are formulated with a combination of tart, sweet and black cherry whole fruit extracts concentrated for flavonoids, including anthocyanins, to provide free radical protection and help joint health.

Bluebonnet's KOF-K Certification #K-0000700

Formulation

Free of milk, egg, fish, crustacean shellfish, tree nuts, peanuts, wheat, soybeans and sesame. Also free of corn, gluten, barley, rice, sodium and sugar.

Free radical protection & joint health

Non GMO

Vegan

Gluten free

Precautions

Caution: For adults only.

Consult physician if pregnant/nursing, taking medication, or have a medical condition.

Keep out of reach of children.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

Vegan

K Parve (Kosher)

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take two capsules once daily or as directed by a healthcare practitioner.

Storage

Store tightly closed in a cool, dry place.

See for yourself

Cherry Fruit Extract by Bluebonnet label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Cherry Fruit Extract by Bluebonnet

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Cherry Fruit Extract Blend

1000 mg per serving

Other (inactive) ingredients: Cellulose, Hypromellose, Water, Purified, Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Cherry Fruit Extract by Bluebonnet Drug Interactions

Want to check YOUR meds against Cherry Fruit Extract?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
643Drugs
643 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Cherry Fruit Extract with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Black Cherry Fruit Extract1 drug type · 643 drugs

Cytochrome P450 3A4 (Cyp3A4) Substrates

In vitro research suggests that wild cherry can inhibit cytochrome P450 3A4 (CYP3A4) enzymes. Theoretically, wild cherry might increase levels of drugs metabolized by CYP3A4. However, so far, this interaction has not been reported in humans.
Some drugs metabolized by CYP3A4 include lovastatin (Mevacor), ketoconazole (Nizoral), itraconazole (Sporanox), fexofenadine (Allegra), triazolam (Halcion), and others.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Cherry Fruit Extract, from the product label.

Bluebonnet

Name
Bluebonnet Nutrition Corporation
Street Address
12915 Dairy Ashford
City
Sugar Land
State
Texas
ZipCode
77478
Web Address
www.bluebonnetnutrition.com
Pharmacist Counseling Corner

Cherry Fruit Extract by Bluebonnet: Common Questions

Does Cherry Fruit Extract by Bluebonnet interact with any medications?
Yes. Based on its ingredients, Cherry Fruit Extract has a known interaction with 643 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Cherry Fruit Extract contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe to take while I'm pregnant or breastfeeding?
Tart cherry and sweet cherry are likely safe in both pregnancy and lactation. Black cherry, however, should be avoided during pregnancy and should not be used while breastfeeding—safety data is lacking. Since this product contains all three, talk with your doctor or pharmacist about whether it's right for you in either situation.
What are the side effects?
Tart cherry most commonly causes abdominal pain, loose stools, or stomach upset; a small number of people experience these. Sweet cherry can trigger allergic reactions—mild mouth irritation to hives, swelling, or difficulty breathing—in people who are sensitive. Black cherry in large amounts can cause serious cyanide toxicity, though the concentrated dose in a capsule carries lower risk than eating hundreds of raw cherries.
Does this actually work for muscle soreness or athletic performance?
Tart cherry is possibly effective for athletic performance, which is the strongest evidence in this product. For exercise-induced muscle soreness and other uses, the research isn't reliable enough yet to say whether it works. If that's what you're after, discuss realistic expectations with your doctor.
Why does this have so many medication interactions listed?
The black cherry extract can inhibit a liver enzyme (CYP3A4) that breaks down hundreds of common medications. Even though this interaction hasn't been seen in real patients yet, the theoretical risk touches a huge number of drugs—that's why the number is so high. Your specific medications might not be affected, which is why checking your list with your pharmacist matters.
Can I take this if I'm allergic to cherries?
No, you should not. Sweet cherry especially can cause allergic reactions ranging from mild mouth irritation to serious swelling and breathing difficulty in sensitive people. If you have a known cherry allergy, skip this product and tell your doctor.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Cherry Fruit Extract is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Cherry Fruit Extract label
Sources

Sources & How We Checked

Cherry Fruit Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Sour Cherry 4 references
  1. Schumacher HR, Pullman-Mooar S, Gupta SR, et al. Randomized double-blind crossover study of the efficacy of a tart cherry juice blend in treatment of osteoarthritis (OA) of the knee. Osteoarthritis Cartilage 2013;21(8):1035-41. PubMed
  2. Seymour EM, Warber SM, Kirakosyan A, et al. Anthocyanin pharmacokinetics and dose-dependent plasma antioxidant pharmacodynamics following whole tart cherry intake in healthy humans. J Funct Food 2014;11:509-16. DOI
  3. Elliot DL, Kuehl KS, Jones KD, Dulacki K. Using an eccentric exercise-testing protocol to assess the beneficial effects of tart cherry juice in fibromyalgia patients. Integ Med 2010;9(6):25-9.
  4. Soltanifar A, Moharreri F, Bakhtiari E, Hosseinpour A. The Effect of Adding Sour Cherry Concentrate to The Usual Treatment of Attention Deficit Hyperactivity Disorder In 6 To 12 Years Old Children. J Atten Disord 2023;27(2):214-219. PubMed

See these in context on the Sour Cherry monograph →

Wild Cherry 4 references
  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  2. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  3. Budzinski JW, Foster BC, Vandenhoek S, Arnason JT. An in vitro evaluation of human cytochrome P450 3A4 inhibition by selected commercial herbal extracts and tinctures. Phytomedicine 2000;7:273-82. PubMed
  4. Pentore, R., Venneri, A., and Nichelli, P. Accidental choke-cherry poisoning: early symptoms and neurological sequelae of an unusual case of cyanide intoxication. Ital.J Neurol.Sci. 1996;17(3):233-235. PubMed

See these in context on the Wild Cherry monograph →

Sweet Cherry 3 references
  1. Serrano M, Guillen F, Martinez-Romero D, et al. Chemical constiuents and antioxidant activity of sweet cherry at different ripening stages. J Agric Food Chem 2005;53:2741-5.
  2. Ballmer-Weber BK, Scheurer S, Fritsche P, et al. Component-resolved diagnosis with recombinant allergens in patients with cherry allergy. J Allergy Clin Immunol 2002;110:167-73. PubMed
  3. Goncalves B, Landbo AK, Knudsen D, et al. Effect of ripeness and postharvest storage on the phenolic profiles of Cherries (Prunus avium L.). J Agric Food Chem 2004;52:523-30.

See these in context on the Sweet Cherry monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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