Chewables DigestEnz Natural Pomegranate Acai Ingredients & Drug Interactions
by ProEnzol
What is this page for?
First and foremost: checking Chewables DigestEnz Natural Pomegranate Acai against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Chewables DigestEnz Natural Pomegranate Acai is a dietary supplement by ProEnzol with 18 active ingredients. Its ingredients are commonly taken for digestion and bloating, muscle soreness and exercise recovery, inflammation and swelling.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Chewables DigestEnz Natural Pomegranate Acai by ProEnzol
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
This product has 18 active ingredients — all digestive enzymes designed to help break down different components of food. The ones we have data on include protease (breaks down protein), lipase (breaks down fat), lactase (breaks down lactose in dairy), and phytase (helps with mineral absorption).
The rest target carbohydrates, fiber, and other compounds your gut encounters during digestion. These are blended together into a chewable tablet for convenience.
Does it work?
Strong evidence
The evidence for these enzymes is mixed. Lactase is effective for lactose intolerance — that one's well established.
For the others we have data on — protease, lipase, and phytase — the evidence isn't strong enough to rate. They're used for digestive support, but we don't hold reliable evidence that they work for conditions like inflammatory bowel disease, indigestion, or the other purposes they're marketed for.
How safe is it?
Well-documented data
The enzymes in this product are generally well tolerated by adults, though digestive upset or allergic reactions can occur. Rare allergic responses to airborne enzyme powders have been reported in occupational settings, but that's not the same as taking a chewable tablet.
For pregnancy: protease safety hasn't been established, so it's best avoided unless your doctor prescribes it; lipase has little safety data, so check with your doctor first; phytase safety information is insufficient, so avoid unless advised otherwise; lactase is likely safe. For breastfeeding: protease and phytase lack adequate study, so get medical advice first; lipase and lactase have limited data — ask your doctor or pharmacist before regular use.
Meds to double-check
No known interactions
No interactions are documented in our data for the ingredients we could check. However, we hold no interaction data for several enzyme ingredients in this product, so checking your exact medications with the search tool on this page is still a good idea.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.
This is a broad-spectrum digestive enzyme blend. If you have lactose intolerance and want enzyme support, lactase in here is effective.
For other digestive concerns, the evidence isn't strong. If you're pregnant or breastfeeding, talk to your pharmacist or doctor before starting — safety data varies by ingredient.
Run your medications through the checker on this page before you begin.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 4 of 18 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 23, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Chewables DigestEnz Natural Pomegranate Acai, straight from the product label.
| Brand | ProEnzol |
|---|---|
| Barcode (UPC) | 707636129715 |
| Net contents | 90 Vegan Chewable Tablet(s) |
| Market status | On market |
| Date entered into DSLD | Jan 23, 2025 |
| DSLD ID | 322814 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Chewables DigestEnz Natural Pomegranate Acai by ProEnzol, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Total Carbohydrates | 1 Gram(s) | 1% |
| Amylase | 0 NP | -- |
| Protease | 0 NP | -- |
| Lipase | 0 NP | -- |
| Total Sugars | 1 Gram(s) | -- |
| Lactase | 0 NP | -- |
| Cellulase | 0 NP | -- |
| Peptidase | 0 NP | -- |
| Invertase | 0 NP | -- |
| Glucoamylase | 0 NP | -- |
| Alpha-Galactosidase | 0 NP | -- |
| Xylanase | 0 NP | -- |
| Pectinase | 0 NP | -- |
| Maltase | 0 NP | -- |
| Beta-Glucanase | 0 NP | -- |
| Phytase | 0 NP | -- |
| Hemicellulase | 0 NP | -- |
| Diastase | 0 NP | -- |
| ProteaseGL | 20 mg | -- |
| DigestEnz Chewable Blend | 288 mg | -- |
| ProteaseCW | 30 mg | -- |
Other ingredients: Allulose, Tapioca Dextrin, Pomegranate Acai Natural Flavor, Malic Acid, Beet Juice, Natural, Monk Fruit Extract, Magnesium Stearate, Silica
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
ProEnzol Children's DigestEnz provides and excellent, broad-spectrum blend of acid-resistant, non-animal derived digestive enzymes, including gluten-digesting ProteaseGL and casein/whey-digesting ProteaseCW, to assist the body's own enzymes break down and assimilating dietary protein, carbohydrates, fat and fiber, for relief of occasional digestive discomfort.
Sweetened with all-natural allulose
Suggested/Recommended/Usage/Directions
Directions: chew one to two (1-2) tablets at the beginning of each meal, or as directed by your healthcare professional.
Precautions
Caution: if you are pregnant, nursing, have a serious medical condition, or take any medications, consult your healthcare professional before use.
Use only if tamper-evident seal is unbroken.
Keep out of reach of children.
Storage
Store tightly closed in a cool, dry place.
Brand IP Statement(s)
ProteaseGL & ProteaseCW are trademarks of Enzymes Inc.
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, mitigate, cure, or prevent any disease.
FDA Statement of Identity
Dietary Supplement
General Statements
Exclusively for professionals
Formulation
Contains no: sucrose, fructose, dextrose, sugar alcohols, soy, wheat, yeast, gluten, peanuts, tree nuts, eggs, dairy, animal products, artificial colors, flavors and sweeteners or genetically modified organisms (GMOs).
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Chewables DigestEnz Natural Pomegranate Acai by ProEnzol label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Chewables DigestEnz Natural Pomegranate Acai by ProEnzol
These are the 18 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Vegan Chewable Tablet(s) Dosage formTablet Or Pill Servings per container45 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
ProteaseGL
DigestEnz Chewable Blend
ProteaseCW
Other (inactive) ingredients: Allulose, Tapioca Dextrin, Pomegranate Acai Natural Flavor, Malic Acid, Beet Juice, Natural, Monk Fruit Extract, Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.
Chewables DigestEnz Natural Pomegranate Acai by ProEnzol Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Chewables DigestEnz Natural Pomegranate Acai. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Chewables DigestEnz Natural Pomegranate Acai, from the product label.
ProEnzol
See all ProEnzol products- Name
- Enzymes Inc.
- City
- Kansas City
- State
- MO
- ZipCode
- 64153
- Phone Number
- 1-800-637-7893
- Web Address
- www.proenzol.com
Chewables DigestEnz Natural Pomegranate Acai by ProEnzol: Common Questions
Does Chewables DigestEnz Natural Pomegranate Acai by ProEnzol interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is lactase in this product effective for lactose intolerance?
Can I take this if I'm pregnant?
What does protease do?
Is there evidence this blend helps with indigestion?
Can I breastfeed while taking this?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Chewables DigestEnz Natural Pomegranate Acai is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Chewables DigestEnz Natural Pomegranate Acai’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Proteolytic Enzymes (proteases)
Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), trypsin, chymotrypsin, and pancreatin. Peo...
Read the full Proteolytic Enzymes (proteases) monograph → Herb & supplement monographLipase
Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy for people who cannot make enough of their...
Read the full Lipase monograph → Herb & supplement monographLactase
Lactase is a digestive enzyme supplement that helps people who lack enough natural lactase break down lactose, the sugar in milk and dairy. It can reduce gas, bloating, cramping, and diarrhe...
Read the full Lactase monograph → Herb & supplement monographPhytase
Phytase is an enzyme that breaks down phytic acid (phytate) found in grains, beans, nuts, and seeds, which can free up minerals like iron, zinc, and calcium for absorption. It is widely used...
Read the full Phytase monograph →Sources & How We Checked
Chewables DigestEnz Natural Pomegranate Acai's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 12 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Proteolytic Enzymes (proteases) 3 references
- Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
- Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
- Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed
See these in context on the Proteolytic Enzymes (proteases) monograph →
Lipase 1 reference
- Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed
Lactase 1 reference
- Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed
Phytase 7 references
- Lei XG, Weaver JD, Mullaney E, Ullah AH, Azain MJ. Phytase, a new life for an "old" enzyme. Annu Rev Anim Biosci. 2013;1:283-309. PubMed
- Smuts CM, Matsungo TM, Malan L, et al. Effect of small-quantity lipid-based nutrient supplements on growth, psychomotor development, iron status, and morbidity among 6- to 12-mo-old infants in South Africa: a randomized controlled trial. Am J Clin Nutr. 2 PubMed
- van Heemst RC, Sander I, Rooyackers J, et al. Hypersensitivity pneumonitis caused by occupational exposure to phytase. Eur Respir J. 2009;33(6):1507-9. PubMed
- Baur X, Melching-Kollmuss S, Koops F, Strassburger K, Zober A. IgE-mediated allergy to phytase -- a new animal feed additive. Allergy. 2002;57(10):943-5. PubMed
- Doekes G, Kamminga N, Helwegen L, Heederik D. Occupational IgE sensitisation to phytase, a phosphatase derived from Aspergillus niger. Occup Environ Med. 1999;56(7):454-9. PubMed
- Brnic M, Hurrell RF, Songré-Ouattara LT, et al. Effect of phytase on zinc absorption from a millet-based porridge fed to young Burkinabe children. Eur J Clin Nutr. 2017;71(1):137-141. PubMed
- Koshy JC, Sharabi SE, Feldman EM, Hollier LH Jr, Patrinely JR, Soparkar CN. Effect of dietary zinc and phytase supplementation on botulinum toxin treatments. J Drugs Dermatol. 2012;11(4):507-12.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC