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Dietary supplement

Choline 500 mg Ingredients & Drug Interactions

by Viva Vitamins

Choline 500 mg label
See full label image
Capsule Category: Vitamin
Most serious interaction: Minor
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Choline 500 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Minor

Choline 500 mg is a dietary supplement by Viva Vitamins with 1 active ingredient. Its ingredients are commonly taken for liver health and fatty liver, brain and memory support, prenatal nutrition and fetal development.Based on those ingredients, 16 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Choline. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Choline 500 mg by Viva Vitamins

Ask about any prescription or over-the-counter medication and we check it for interactions with Choline 500 mg by Viva Vitamins — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Choline 500 mg by Viva Vitamins

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: choline, a nutrient that plays a role in nerve function, brain health, and cell membrane structure. The capsule also holds two inactive ingredients—microcrystalline cellulose and croscarmellose sodium—which are fillers and binders that help form and hold the capsule together.

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: liver support and cognitive function.
  • We looked for evidence on: Nonalcoholic fatty liver disease (NAFLD), TPN-associated hepatic steatosis, Hepatitis, Cognitive function, Age-related cognitive decline, Dementia — and 4 related terms.
  • The closest evidence on file: Choline is rated "Insufficient Reliable Evidence To Rate" for Age-related cognitive decline (Natural Medicines).
  • Also on file: Choline is rated "Insufficient Reliable Evidence To Rate" for TPN-associated hepatic steatosis, Alzheimer disease, Nonalcoholic fatty liver disease (NAFLD), Cognitive function, and more.

The evidence for choline supplementation is limited for most of the conditions it's studied in. For athletic performance, the data suggests it's likely ineffective.

For age-related cognitive decline, Alzheimer disease, allergies, bronchitis, and a liver condition called TPN-associated hepatic steatosis, we don't have enough reliable evidence in our data to rate whether it works. Talk with your pharmacist about what the research says for your specific health goal.

The evidence, ingredient by ingredient Choline

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Choline at this 500 mg dose is generally well tolerated. Side effects become a concern only at much higher doses—above the daily upper limit of 3.5 grams—where you might experience fishy body odor, nausea, vomiting, diarrhea, or sweating.

Choline is important during pregnancy and breastfeeding, but dosing should be guided by your doctor or prenatal care provider rather than self-supplemented at high levels.

Side effects, ingredient by ingredient Choline

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Choline.
  • The most serious interaction on file is rated Minor.
  • For scale: 16 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take atropine or related anticholinergic medications, check with your pharmacist before starting this supplement—choline may theoretically decrease how well atropine works in your brain.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with insufficient evidence for its stated purpose. Only minor medication interactions are documented, and safety information is well characterized.

Choline 500 mg may be worth considering if your doctor has recommended choline supplementation for a specific reason, though evidence for most uses is weak or unknown. If you take atropine or related anticholinergic drugs, check with your pharmacist first.

Pregnant or breastfeeding women should discuss any supplementation with their healthcare provider.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Choline 500 mg, straight from the product label.

Brand Viva Vitamins
Barcode (UPC) 726899206742
Net contents 100 Tablet(s)
Market status On market
Date entered into DSLD Oct 24, 2024
DSLD ID 316297
Product type Vitamin
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Choline 500 mg by Viva Vitamins, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
Servings per container
100
UPC/BARCODE
726899206742
IngredientAmount% DV
Choline500 mg90%

Other ingredients: Microcrystalline Cellulose, Croscarmellose Sodium

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: Adults take one tablet daily with meals, or as directed by a health care professional.

Formula

Choline is an important nutrient that can help the liver rid the body of excess fat. In doing so, it can also assist with detoxification of the liver, and thus, the whole body. Additionally, choline has been shown to be important for cognitive function.

Storage

Store in a cool, dry place.

Precautions

Keep out of reach of children.

Do not use if safety seal under cap is broken or missing.

General Statements

We at viva are proud to use only the best food-based ingredients in our supplements. Our raw materials come from the USA, and we use only organic sources to ensure you're getting the best product possible, from the ground up!

For more information, visit www.VivaVitamins.com In God We Trust

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formulation

Fat loss and liver support

We always use the highest quality ingredients Premium Formulas

Free of gluten, sugar, salt, yeast, corn, wheat, dairy, citrus, egg, fish products, artificial coloring, flavoring or preservatives. Non-GMO

Made in the USA Manufactured in an NSF-GMP Certified Facility

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

Copyright 2021

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Choline 500 mg by Viva Vitamins label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Choline 500 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Choline 500 mg by Viva Vitamins

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Tablet(s) Dosage formCapsule Servings per container100 Amounts shown are per serving.

Choline

Interacts with
16 drugs
500 mg per serving Form: Choline Bitartrate

Choline is an essential nutrient your body needs for liver function, brain health, and nerve signaling, and many people get enough from foods like egg...

Choline monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Croscarmellose Sodium. These complete the product’s ingredient list but are not active constituents.

Interaction report

Choline 500 mg by Viva Vitamins Drug Interactions

Want to check YOUR meds against Choline 500 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
16Drugs
16 Minor

Ingredients driving the most interactions

Choline 16

Individual Drug Interactions

The ingredients in Choline 500 mg interact with 16 drugs. Click any drug to see the details.

1 of the 1 ingredient in Choline 500 mg interact with drugs. Each result below shows which ingredient is responsible. Choline

Each ingredient & the kinds of drugs it affects

For each ingredient in Choline 500 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Choline1 drug type · 16 drugs

Atropine

Theoretically, choline might decrease the effects of atropine in the brain.
Animal research shows that administering choline one hour before administering atropine can attenuate atropine-induced decreases in brain levels of acetylcholine. Theoretically, concomitant use of choline and atropine may decrease the effects of atropine.

Likelihood Possible Evidence D
Choline full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Choline 500 mg, from the product label.

Viva Vitamins

Name
Viva Vitamins
Web Address
www.VivaVitamins.com
Pharmacist Counseling Corner

Choline 500 mg by Viva Vitamins: Common Questions

Does Choline 500 mg by Viva Vitamins interact with any medications?
Yes. Based on its ingredients, Choline 500 mg has a known interaction with 16 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Choline 500 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe to take if I'm pregnant or breastfeeding?
Choline is important during both pregnancy and breastfeeding, but the right dose depends on your individual situation. Don't self-supplement at high levels—talk with your obstetrician, midwife, or pharmacist about whether a supplement makes sense for you and what dose is appropriate.
What side effects should I watch for at this dose?
At 500 mg daily, choline is generally well tolerated with no expected side effects. Problems only show up at much higher doses—above 3.5 grams per day—where you might notice a fishy body odor, nausea, vomiting, or diarrhea.
Does this product have fillers or other inactive ingredients?
Yes, it contains two inactive ingredients: microcrystalline cellulose and croscarmellose sodium. These are binders and fillers that help form the capsule.
Will this help my memory or brain health?
The evidence for choline on age-related cognitive decline and Alzheimer disease is insufficient—we don't have enough reliable data to say whether it works. If you're interested in brain health, your pharmacist can point you toward better-studied options or discuss what the current research actually shows.
Can I take this if I use atropine or anticholinergic medications?
Choline may theoretically reduce how well atropine works by raising acetylcholine levels in the brain. Before starting this supplement, check with your pharmacist, especially if you take atropine or similar drugs like benztropine or scopolamine.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Choline 500 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Choline 500 mg label
Go deeper

The Full Monographs Behind Choline 500 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Choline

Interacts with 16 drugs

Choline is an essential nutrient your body needs for liver function, brain health, and nerve signaling, and many people get enough from foods like eggs, meat, and fish. Supplements may help...

Read the full Choline monograph →
Sources

Sources & How We Checked

Choline 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Choline 14 references
  1. Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
  2. Cho E, Willett WC, Colditz GA, et al. Dietary choline and betaine and the risk of distal colorectal adenoma in women. J Natl Cancer Inst 2007;99:1224-31. PubMed
  3. Schmidt, C., Abicht, A., Krampfl, K., Voss, W., Stucka, R., Mildner, G., Petrova, S., Schara, U., Mortier, W., Bufler, J., Huebner, A., and Lochmuller, H. Congenital myasthenic syndrome due to a novel missense mutation in the gene encoding choline acetyl
  4. Tamminga, C., Smith, R. C., Chang, S., Haraszti, J. S., and Davis, J. M. Depression associated with oral choline. Lancet 10-23-1976;2(7991):905. PubMed
  5. Wood, J. L. and Allison, R. G. Effects of consumption of choline and lecithin on neurological and cardiovascular systems. Fed.Proc. 1982;41(14):3015-3021.
  6. Growdon, J. H. and Gelenberg, A. J. Choline and lecithin administration to patients with tardive dyskinesia. Trans.Am.Neurol.Assoc. 1978;103:95-99.
  7. Smith, C. M., Swash, M., Exton-Smith, A. N., Phillips, M. J., Overstall, P. W., Piper, M. E., and Bailey, M. R. Choline therapy in Alzheimer's disease. Lancet 8-5-1978;2(8084):318. PubMed
  8. Morrison, L. M. and W. F. Gonzales. Choline in coronary atherosclerosis. Amer.Heart J. 1950;39:729.
  9. Christie, J. G. Blackburn 1. M. Glen A. I. M. Zeisel S. Shering A. & Yates C. M. Effects of choline and lecithin on CSF choline levels and on cognitive functioning in patients with presenile dementia of the Alzheimer type. Nutrition and the brain 1979;5
  10. Sidhu N, Davies S, Nadarajah A, et al. Oral choline supplementation for postoperative pain. Br J Anaesth 2013;111(2):249-55. PubMed
  11. Wozniak JR, Fuglestad AJ, Eckerle JK, et al. Choline supplementation in children with fetal alcohol spectrum disorders has high feasibility and tolerability. Nutr Res. 2013;33(11):897-904. PubMed
  12. Wozniak JR, Fuglestad AJ, Eckerle JK, et al. Choline supplementation in children with fetal alcohol disorders: a randomized, double-blind, placebo-controlled trial. Am J Clin Nutr. 2015;102(5): 1113-25.
  13. Ross RG, Hunter SK, McCarthy L, et al. Perinatal choline effects on neonatal pathophysiology related to later schizophrenia risk. Am J Psychiatry. 2013;170(3):290-8. PubMed
  14. Food and Nutrition Board, Institute of Medicine. Choline. Dietary Reference Intakes: Thiamin, Riboflavin, Niacin, Vitamin B-6, Vitamin B-12, Pantothenic Acid, Biotin, and Choline. Washington D.C.: National Academy Press; 1998:390-422.

See these in context on the Choline monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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