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Dietary supplement

Choline Bitartrate 650 mg Ingredients & Drug Interactions

by AN Amazing Nutrition Amazing Formulas

Choline Bitartrate 650 mg label
See full label image
Tablet Or Pill Category: Non-nutrient/non-botanical
Most serious interaction: Minor
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Choline Bitartrate 650 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Minor

Choline Bitartrate 650 mg is a dietary supplement by AN Amazing Nutrition Amazing Formulas with 1 active ingredient. Its ingredients are commonly taken for liver health and fatty liver, brain and memory support, prenatal nutrition and fetal development.Based on those ingredients, 16 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are DL-Choline Bitartrate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Choline Bitartrate 650 mg by AN Amazing Nutrition Amazing Formulas

Ask about any prescription or over-the-counter medication and we check it for interactions with Choline Bitartrate 650 mg by AN Amazing Nutrition Amazing Formulas — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Choline Bitartrate 650 mg by AN Amazing Nutrition Amazing Formulas

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: choline bitartrate, a form of choline that supplies 650 mg per tablet. Choline is a nutrient your body uses to make acetylcholine, a chemical messenger involved in brain and muscle function, and to support cell structure and fat metabolism.

The remaining ingredients are inert fillers and binders that help form the tablet.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Choline's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: brain supplement and neurotransmitter support.
  • We looked for evidence on: Age-related cognitive decline, Alzheimer disease, Cognitive function, Dementia, Infant development, Neural tube birth defects — and 3 related terms.
  • The closest evidence on file: Choline is rated "Insufficient Reliable Evidence To Rate" for Age-related cognitive decline (Natural Medicines).
  • Also on file: Choline is rated "Insufficient Reliable Evidence To Rate" for Alzheimer disease, Cognitive function, Dementia, Neural tube birth defects, and more.

The evidence for choline bitartrate on the conditions listed is mixed. For athletic performance, the data suggests it's likely ineffective.

For Alzheimer's disease, age-related cognitive decline, bronchitis, hay fever, liver damage from total parenteral nutrition (TPN), and other uses, there simply isn't enough reliable evidence yet to rate whether it works. If you're considering it for a specific condition, talk with your doctor about whether the current evidence supports its use for you.

The evidence, ingredient by ingredient Choline

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Choline bitartrate is well tolerated at normal doses. The tolerable upper limit is 3.5 grams daily; doses above that have caused side effects including fishy body odor, nausea, vomiting, diarrhea, sweating, and salivation.

At very high doses (32 grams daily), more severe gastrointestinal discomfort has been reported. This tablet supplies 650 mg, so you'd need to take multiple tablets daily to reach those upper limits.

During pregnancy and breastfeeding, choline is important for your baby's development and your own needs are higher while nursing. The safety data rates choline as likely safe in these periods, but use only prenatal or supplement doses as your doctor advises — don't decide the dose on your own.

Side effects, ingredient by ingredient Choline

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Choline.
  • The most serious interaction on file is rated Minor.
  • For scale: 16 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take atropine, double-check this product with your doctor or pharmacist before you start — choline may theoretically reduce its effects. We hold data on atropine specifically; for any other medications you take, use the interaction checker below to be sure.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Only minor medication interactions are documented, and safety information is well characterized.

Choline bitartrate may be worth considering if your doctor recommends it for your specific situation, though evidence for most uses is limited. If you take atropine or any prescription medications, check with your doctor or pharmacist before you start.

Pregnant or breastfeeding women should use it only under professional guidance. At the standard dose on this label, it's generally well tolerated.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Choline Bitartrate 650 mg, straight from the product label.

Brand AN Amazing Nutrition Amazing Formulas
Barcode (UPC) 810180024501
Net contents 180 Tablet(s)
Market status On market
Date entered into DSLD Aug 23, 2021
DSLD ID 251722
Product type Non-nutrient/non-botanical
Supplement form Tablet Or Pill
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Choline Bitartrate 650 mg by AN Amazing Nutrition Amazing Formulas, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
Servings per container
180
UPC/BARCODE
810180024501
IngredientAmount% DV
DL-Choline Bitartrate650 mg--

Other ingredients: Dicalcium Phosphate Dihydrate, Microcrystalline Cellulose, Croscarmellose Sodium, Stearic Acid Food Grade, Vegetable Magnesium Stearate, Pharmaceutical Glaze and Tale

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

We believe that Amazing Nutrition is the key for healthy living. We are passionate about bringing you the finest selection of products which can perfectly complement a healthy diet and active lifestyle.

Vitamin angels Proud supporter

Formula

Choline Bitartrate is a brain supplement and a form of the nutrient choline, which is considered part of the group of B complex vitamins. Amazing Formulas Choline Bitartrate is a precursor to the neurotransmitter acetylcholine, which is crucial to mood, thought and learning. Choline Bitartrate supports nerve development and the growth and production of cell membranes. It is essential to the proper functioning of the brain and nervous system.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Precautions

Keep out of reach of children.

Do not use if safety seal is damaged or missing.

Caution: If you are pregnant, nursing, taking any medication(s) or have any medical condition, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Storage

Store in a cool, dry place.

Formulation

Amazing Nutrition an FDA regulated facility

Cognitive support Promotes cellular function Supports nerve & brain health

Contains No: Shellfish, egg, fish, peanuts, milk, soy, tree nuts or wheat.

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

Made In USA GMP Good Manufacturing Practice Quality Product

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, adults take one (1) tablet daily, preferably with a meal or as directed by a health care professional.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Choline Bitartrate 650 mg by AN Amazing Nutrition Amazing Formulas label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Choline Bitartrate 650 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Choline Bitartrate 650 mg by AN Amazing Nutrition Amazing Formulas

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container180 Amounts shown are per serving.

DL-Choline Bitartrate

Interacts with
16 drugs
650 mg per serving

Choline is an essential nutrient your body needs for liver function, brain health, and nerve signaling, and many people get enough from foods like egg...

DL-Choline Bitartrate monograph & interactions

Other (inactive) ingredients: Dicalcium Phosphate Dihydrate, Microcrystalline Cellulose, Croscarmellose Sodium, Stearic Acid Food Grade, Vegetable Magnesium Stearate, Pharmaceutical Glaze and Tale. These complete the product’s ingredient list but are not active constituents.

Interaction report

Choline Bitartrate 650 mg by AN Amazing Nutrition Amazing Formulas Drug Interactions

Want to check YOUR meds against Choline Bitartrate 650 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
16Drugs
16 Minor

Ingredients driving the most interactions

DL-Choline Bitartrate 16

Individual Drug Interactions

The ingredients in Choline Bitartrate 650 mg interact with 16 drugs. Click any drug to see the details.

1 of the 1 ingredient in Choline Bitartrate 650 mg interact with drugs. Each result below shows which ingredient is responsible. DL-Choline Bitartrate

Each ingredient & the kinds of drugs it affects

For each ingredient in Choline Bitartrate 650 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

DL-Choline Bitartrate1 drug type · 16 drugs

Atropine

Theoretically, choline might decrease the effects of atropine in the brain.
Animal research shows that administering choline one hour before administering atropine can attenuate atropine-induced decreases in brain levels of acetylcholine. Theoretically, concomitant use of choline and atropine may decrease the effects of atropine.

Likelihood Possible Evidence D
DL-Choline Bitartrate full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Choline Bitartrate 650 mg, from the product label.

AN Amazing Nutrition Amazing Formulas

See all AN Amazing Nutrition Amazing Formulas products
Name
Amazing Nutrition
City
Jersey City
State
NJ
ZipCode
07310
Phone Number
1-800-526-0177
Web Address
amazingnutrition.com
Pharmacist Counseling Corner

Choline Bitartrate 650 mg by AN Amazing Nutrition Amazing Formulas: Common Questions

Does Choline Bitartrate 650 mg by AN Amazing Nutrition Amazing Formulas interact with any medications?
Yes. Based on its ingredients, Choline Bitartrate 650 mg has a known interaction with 16 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Choline Bitartrate 650 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while I'm pregnant or breastfeeding?
Choline is important during pregnancy and your needs are higher while breastfeeding, and it's rated likely safe in both periods. But don't pick your own dose — use only prenatal or supplement amounts as your doctor advises, so you get the right amount for you and your baby.
Will this give me the fishy body odor I've heard about?
Fishy body odor is a documented side effect, but it tends to happen at high doses. At 650 mg per tablet, you're well below the upper safe limit of 3.5 grams daily, so it's unlikely — though some people are more sensitive than others.
Does choline actually improve brain function or athletic performance?
For athletic performance, the evidence suggests it's likely ineffective. For cognitive decline and Alzheimer's disease, there isn't enough reliable evidence yet to say whether it works. Your doctor can help you decide if it's worth trying for your specific situation.
What exactly is choline bitartrate, and why is it in this form?
Choline bitartrate is choline bound to tartaric acid, a form designed for oral supplements. Your body uses choline to make acetylcholine, a chemical messenger in your brain and nerves, and to build and maintain cell membranes.
Is there anything else in this tablet besides choline?
The only active ingredient is choline bitartrate. The tablet also contains inactive ingredients like microcrystalline cellulose, dicalcium phosphate, and magnesium stearate — standard binders and fillers that help hold the tablet together.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Choline Bitartrate 650 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Choline Bitartrate 650 mg label
Go deeper

The Full Monographs Behind Choline Bitartrate 650 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Choline

Interacts with 16 drugs

Choline is an essential nutrient your body needs for liver function, brain health, and nerve signaling, and many people get enough from foods like eggs, meat, and fish. Supplements may help...

Read the full Choline monograph →
Sources

Sources & How We Checked

Choline Bitartrate 650 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Choline 14 references
  1. Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
  2. Cho E, Willett WC, Colditz GA, et al. Dietary choline and betaine and the risk of distal colorectal adenoma in women. J Natl Cancer Inst 2007;99:1224-31. PubMed
  3. Schmidt, C., Abicht, A., Krampfl, K., Voss, W., Stucka, R., Mildner, G., Petrova, S., Schara, U., Mortier, W., Bufler, J., Huebner, A., and Lochmuller, H. Congenital myasthenic syndrome due to a novel missense mutation in the gene encoding choline acetyl
  4. Tamminga, C., Smith, R. C., Chang, S., Haraszti, J. S., and Davis, J. M. Depression associated with oral choline. Lancet 10-23-1976;2(7991):905. PubMed
  5. Wood, J. L. and Allison, R. G. Effects of consumption of choline and lecithin on neurological and cardiovascular systems. Fed.Proc. 1982;41(14):3015-3021.
  6. Growdon, J. H. and Gelenberg, A. J. Choline and lecithin administration to patients with tardive dyskinesia. Trans.Am.Neurol.Assoc. 1978;103:95-99.
  7. Smith, C. M., Swash, M., Exton-Smith, A. N., Phillips, M. J., Overstall, P. W., Piper, M. E., and Bailey, M. R. Choline therapy in Alzheimer's disease. Lancet 8-5-1978;2(8084):318. PubMed
  8. Morrison, L. M. and W. F. Gonzales. Choline in coronary atherosclerosis. Amer.Heart J. 1950;39:729.
  9. Christie, J. G. Blackburn 1. M. Glen A. I. M. Zeisel S. Shering A. & Yates C. M. Effects of choline and lecithin on CSF choline levels and on cognitive functioning in patients with presenile dementia of the Alzheimer type. Nutrition and the brain 1979;5
  10. Sidhu N, Davies S, Nadarajah A, et al. Oral choline supplementation for postoperative pain. Br J Anaesth 2013;111(2):249-55. PubMed
  11. Wozniak JR, Fuglestad AJ, Eckerle JK, et al. Choline supplementation in children with fetal alcohol spectrum disorders has high feasibility and tolerability. Nutr Res. 2013;33(11):897-904. PubMed
  12. Wozniak JR, Fuglestad AJ, Eckerle JK, et al. Choline supplementation in children with fetal alcohol disorders: a randomized, double-blind, placebo-controlled trial. Am J Clin Nutr. 2015;102(5): 1113-25.
  13. Ross RG, Hunter SK, McCarthy L, et al. Perinatal choline effects on neonatal pathophysiology related to later schizophrenia risk. Am J Psychiatry. 2013;170(3):290-8. PubMed
  14. Food and Nutrition Board, Institute of Medicine. Choline. Dietary Reference Intakes: Thiamin, Riboflavin, Niacin, Vitamin B-6, Vitamin B-12, Pantothenic Acid, Biotin, and Choline. Washington D.C.: National Academy Press; 1998:390-422.

See these in context on the Choline monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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