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Dietary supplement

Choline Citrate Ingredients & Drug Interactions

by SNS Serious Nutrition Solutions

Choline Citrate label
See full label image
Powder Category: Vitamin
Most serious interaction: Minor
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Choline Citrate against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Minor

Choline Citrate is a dietary supplement by SNS Serious Nutrition Solutions with 1 active ingredient. Its ingredients are commonly taken for liver health and fatty liver, brain and memory support, prenatal nutrition and fetal development.Based on those ingredients, 16 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Choline Citrate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Choline Citrate by SNS Serious Nutrition Solutions

Ask about any prescription or over-the-counter medication and we check it for interactions with Choline Citrate by SNS Serious Nutrition Solutions — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Choline Citrate by SNS Serious Nutrition Solutions

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Choline Citrate contains one active ingredient: choline citrate, a form of choline. Choline is a nutrient your body uses to support memory, brain health, and muscle function.

This product contains no other active ingredients.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Choline's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: positive mood, focus and concentration.
  • We looked for evidence on: Age-related cognitive decline, Alzheimer disease, Cognitive function, Dementia, Depression, Mental clarity — and 3 related terms.
  • The closest evidence on file: Choline is rated "Insufficient Reliable Evidence To Rate" for Age-related cognitive decline (Natural Medicines).
  • Also on file: Choline is rated "Insufficient Reliable Evidence To Rate" for Alzheimer disease, Cognitive function, Dementia, Depression.

The evidence for choline citrate's effectiveness varies by use. For athletic performance, the data suggests it's possibly ineffective.

For other claimed uses—including age-related cognitive decline, Alzheimer disease, allergic rhinitis (hay fever), bronchitis, and a liver condition called TPN-associated hepatic steatosis—there isn't enough reliable evidence yet to say whether it works. If you're considering this for a specific condition, talk with your doctor about whether the evidence supports its use for your situation.

The evidence, ingredient by ingredient Choline

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Choline is well tolerated when used at appropriate doses. However, high-dose supplements can cause side effects and have an upper safe limit of 3.5 grams daily.

At doses of 9 grams or more, choline has been reported to cause diarrhea, nausea, salivation, sweating, vomiting, and a distinctive fishy body odor from how your body breaks it down. During pregnancy and breastfeeding, choline is important for your baby's development and your own health, but you should use it only at doses recommended by your doctor.

The data supports that it's likely safe at appropriate doses during these times, but personalized guidance from your healthcare provider is essential.

Side effects, ingredient by ingredient Choline

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Choline.
  • The most serious interaction on file is rated Minor.
  • For scale: 16 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take atropine (used for certain eye conditions and other purposes), let your doctor know you're considering choline citrate — it may theoretically decrease atropine's effects in the brain. No interactions are documented for the other medications in our data, but run your exact prescriptions through the checker on this page to be sure.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Only minor medication interactions are documented, and safety information is well characterized.

Choline Citrate may be considered by people looking to support brain and muscle function, though the evidence for specific health claims is mixed or limited. If you take atropine or any other medications, check them against this product first with your doctor or pharmacist.

Pregnant or breastfeeding women should only use it under professional guidance at recommended doses. Keep your doses below the upper limit of 3.5 grams daily to avoid side effects.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 16, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Choline Citrate, straight from the product label.

Brand SNS Serious Nutrition Solutions
Barcode (UPC) 850008039539
Net contents 500 Gram(s); 17.06 oz
Market status On market
Date entered into DSLD Jun 16, 2022
DSLD ID 266041
Product type Vitamin
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Choline Citrate by SNS Serious Nutrition Solutions, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
500 mg
Maximum serving Sizes:
1000 mg
Servings per container
500
UPC/BARCODE
850008039539
IngredientAmount% DV
Choline Citrate1000 mg--

Other ingredients: None

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Positive mood, focus & concentration 500 servings

Choline Citrate highlights/supports: Positive mood Improved focus Mental alertness Concentration 500 servings

SNS Choline Citrate can be stacked with Focus XT, Stress & Anxiety Support, PEA-500 Xtreme, Huperzine A 99%, or other select SNS products for improved synergistic results.

SNS Baseline Series Straight forward, cost effective sports nutrition.

To report a serious adverse event, or obtain product information, contact Serious Nutrition Solutions, LLC. at 1-877-799-8778. www.SeriousNutritionSolutions.com

Formulation

Choline Citrate is a unique form of Choline that is commonly used to help support positive mood, focus, and concentration.

Supports positive mood, focus, & concentration

Allergen Information: Not manufactured with yeast, wheat, gluten, soy, milk, egg, fish, shellfish, or tree nut ingredients.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Seals/Symbols

GMP Good Manufacturing Practices Product

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take 1/2 to one (1) scoop once or twice per day.

Precautions

Allergen Information: Not manufactured with yeast, wheat, gluten, soy, milk, egg, fish, shellfish, or tree nut ingredients. Produced in a GMP facility that may process other ingredients containing these allergens.

Warning: This product is intended for healthy adults over 18 years of age.

Do not use this product if you are pregnant or nursing. Consult your physician before using this or any dietary supplement, especially if you are taking any medication or suffer from any health condition(s).

Keep stored in a cool, dry place away from children and animals.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Choline Citrate by SNS Serious Nutrition Solutions label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Choline Citrate label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Choline Citrate by SNS Serious Nutrition Solutions

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size500 mg Dosage formPowder Servings per container500 Amounts shown are per serving.

Choline Citrate

Interacts with
16 drugs
1000 mg per serving

Choline is an essential nutrient your body needs for liver function, brain health, and nerve signaling, and many people get enough from foods like egg...

Choline Citrate monograph & interactions

Other (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.

Interaction report

Choline Citrate by SNS Serious Nutrition Solutions Drug Interactions

Want to check YOUR meds against Choline Citrate?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
16Drugs
16 Minor

Ingredients driving the most interactions

Choline Citrate 16

Individual Drug Interactions

The ingredients in Choline Citrate interact with 16 drugs. Click any drug to see the details.

1 of the 1 ingredient in Choline Citrate interact with drugs. Each result below shows which ingredient is responsible. Choline Citrate

Each ingredient & the kinds of drugs it affects

For each ingredient in Choline Citrate with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Choline Citrate1 drug type · 16 drugs

Atropine

Theoretically, choline might decrease the effects of atropine in the brain.
Animal research shows that administering choline one hour before administering atropine can attenuate atropine-induced decreases in brain levels of acetylcholine. Theoretically, concomitant use of choline and atropine may decrease the effects of atropine.

Likelihood Possible Evidence D
Choline Citrate full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Choline Citrate, from the product label.

SNS Serious Nutrition Solutions

See all SNS Serious Nutrition Solutions products
Name
Serious Nutrition Solutions, LLC
City
Danville
State
VA
ZipCode
24540
Phone Number
877-799-8778
Web Address
www.SeriousNutritionSolutions.com
Pharmacist Counseling Corner

Choline Citrate by SNS Serious Nutrition Solutions: Common Questions

Does Choline Citrate by SNS Serious Nutrition Solutions interact with any medications?
Yes. Based on its ingredients, Choline Citrate has a known interaction with 16 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Choline Citrate contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What's choline citrate for?
Choline is a nutrient your body needs for brain health, memory, and muscle function. This product provides choline in citrate form. The evidence for specific health claims like boosting athletic performance or protecting your memory varies — some uses have limited or unclear evidence, so talk with your doctor about whether it's right for what you're aiming for.
Is this safe to take every day?
Choline is generally well tolerated at normal doses, but there's an upper safe limit of 3.5 grams daily. Going over that can cause side effects like a fishy body odor, nausea, diarrhea, and sweating. Keep your daily dose below that threshold and check the label to see how much this powder delivers per serving.
Can I take this while pregnant or breastfeeding?
Choline is actually important during pregnancy and breastfeeding for your baby's development and your own health. The data shows it's likely safe at appropriate doses, but you should only use it at doses your doctor recommends—not at your own guess. Talk with your obstetrician or midwife about what's right for you.
What side effects can choline cause?
At normal doses, side effects are rare. But at high doses of 9 grams or more daily, choline can cause nausea, vomiting, diarrhea, salivation, sweating, and a fishy body odor. Very high doses may also cause stomach discomfort. Staying below the 3.5-gram daily upper limit helps you avoid these.
Does this interact with my medications?
Choline may theoretically decrease the effects of atropine (an eye and other medication) in the brain. No other interactions are documented in our data for the medications we've checked, but run your exact prescriptions through the checker on this page or talk with your pharmacist to be certain.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Choline Citrate is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Choline Citrate label
Go deeper

The Full Monographs Behind Choline Citrate’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Choline

Interacts with 16 drugs

Choline is an essential nutrient your body needs for liver function, brain health, and nerve signaling, and many people get enough from foods like eggs, meat, and fish. Supplements may help...

Read the full Choline monograph →
Sources

Sources & How We Checked

Choline Citrate's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Choline 14 references
  1. Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
  2. Cho E, Willett WC, Colditz GA, et al. Dietary choline and betaine and the risk of distal colorectal adenoma in women. J Natl Cancer Inst 2007;99:1224-31. PubMed
  3. Schmidt, C., Abicht, A., Krampfl, K., Voss, W., Stucka, R., Mildner, G., Petrova, S., Schara, U., Mortier, W., Bufler, J., Huebner, A., and Lochmuller, H. Congenital myasthenic syndrome due to a novel missense mutation in the gene encoding choline acetyl
  4. Tamminga, C., Smith, R. C., Chang, S., Haraszti, J. S., and Davis, J. M. Depression associated with oral choline. Lancet 10-23-1976;2(7991):905. PubMed
  5. Wood, J. L. and Allison, R. G. Effects of consumption of choline and lecithin on neurological and cardiovascular systems. Fed.Proc. 1982;41(14):3015-3021.
  6. Growdon, J. H. and Gelenberg, A. J. Choline and lecithin administration to patients with tardive dyskinesia. Trans.Am.Neurol.Assoc. 1978;103:95-99.
  7. Smith, C. M., Swash, M., Exton-Smith, A. N., Phillips, M. J., Overstall, P. W., Piper, M. E., and Bailey, M. R. Choline therapy in Alzheimer's disease. Lancet 8-5-1978;2(8084):318. PubMed
  8. Morrison, L. M. and W. F. Gonzales. Choline in coronary atherosclerosis. Amer.Heart J. 1950;39:729.
  9. Christie, J. G. Blackburn 1. M. Glen A. I. M. Zeisel S. Shering A. & Yates C. M. Effects of choline and lecithin on CSF choline levels and on cognitive functioning in patients with presenile dementia of the Alzheimer type. Nutrition and the brain 1979;5
  10. Sidhu N, Davies S, Nadarajah A, et al. Oral choline supplementation for postoperative pain. Br J Anaesth 2013;111(2):249-55. PubMed
  11. Wozniak JR, Fuglestad AJ, Eckerle JK, et al. Choline supplementation in children with fetal alcohol spectrum disorders has high feasibility and tolerability. Nutr Res. 2013;33(11):897-904. PubMed
  12. Wozniak JR, Fuglestad AJ, Eckerle JK, et al. Choline supplementation in children with fetal alcohol disorders: a randomized, double-blind, placebo-controlled trial. Am J Clin Nutr. 2015;102(5): 1113-25.
  13. Ross RG, Hunter SK, McCarthy L, et al. Perinatal choline effects on neonatal pathophysiology related to later schizophrenia risk. Am J Psychiatry. 2013;170(3):290-8. PubMed
  14. Food and Nutrition Board, Institute of Medicine. Choline. Dietary Reference Intakes: Thiamin, Riboflavin, Niacin, Vitamin B-6, Vitamin B-12, Pantothenic Acid, Biotin, and Choline. Washington D.C.: National Academy Press; 1998:390-422.

See these in context on the Choline monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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