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Dietary supplement

Choline L-Bitartrate Capsules Ingredients & Drug Interactions

by Nootropics Depot

Choline L-Bitartrate Capsules label
See full label image
Capsule Category: Vitamin
Most serious interaction: Minor
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Choline L-Bitartrate Capsules against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Minor

Choline L-Bitartrate Capsules is a dietary supplement by Nootropics Depot with 1 active ingredient. Its ingredients are commonly taken for liver health and fatty liver, brain and memory support, prenatal nutrition and fetal development.Based on those ingredients, 16 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Choline L-Bitartrate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Choline L-Bitartrate Capsules by Nootropics Depot

Ask about any prescription or over-the-counter medication and we check it for interactions with Choline L-Bitartrate Capsules by Nootropics Depot — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Choline L-Bitartrate Capsules by Nootropics Depot

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: choline L-bitartrate, a form of choline — a nutrient your body uses to make acetylcholine, a chemical messenger in your brain and nerves, and to support cell membrane function and fat metabolism. The capsule also contains inactive ingredients (silicon dioxide, magnesium stearate, and vegetable cellulose) that serve as a filler and binder.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Choline product and its label doesn't state a use — see Choline's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence on choline L-bitartrate for most uses is mixed or not yet established. For athletic performance, the data suggests it's probably ineffective.

For Alzheimer disease, age-related cognitive decline, bronchitis, hay fever, and a specific liver condition tied to nutritional support (TPN-associated hepatic steatosis), there isn't enough reliable evidence yet to say whether it works. Talk with your doctor about whether choline is a fit for what you're hoping to address.

The evidence, ingredient by ingredient Choline

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Choline is well tolerated at typical doses. However, high-dose supplements can cause side effects, and there's a daily upper limit of 3.5 grams.

At doses of 9 grams or higher, people have reported diarrhea, nausea, vomiting, sweating, and salivation. A fishy body odor can occur at high doses due to how your gut breaks down choline.

Choline is important during pregnancy and breastfeeding, but the safety data advises using only prenatal vitamins or supplement doses as your doctor recommends — not on your own initiative. Talk with your doctor or pharmacist before starting this supplement if you're pregnant or nursing.

Side effects, ingredient by ingredient Choline

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Choline.
  • The most serious interaction on file is rated Minor.
  • For scale: 16 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take atropine (a medication that blocks certain nerve signals), check with your doctor or pharmacist before adding this product — choline may reduce how well atropine works in your brain. No other interactions are documented for the ingredient we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Only minor medication interactions are documented, and safety information is well characterized.

Choline L-bitartrate may be worth considering if your doctor has suggested choline supplementation, though evidence for many common uses is still limited. If you take atropine or any other prescription medication, check it against this product's interaction data before you start.

Pregnant and breastfeeding individuals should confirm any dose with their doctor or pharmacist first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 23, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Choline L-Bitartrate Capsules, straight from the product label.

Brand Nootropics Depot
Net contents 15 Capsule(s)
Market status On market
Date entered into DSLD Jun 23, 2021
DSLD ID 251130
Product type Vitamin
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Choline L-Bitartrate Capsules by Nootropics Depot, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
15
IngredientAmount% DV
Choline L-Bitartrate500 mg--

Other ingredients: Silicon Dioxide, Magnesium Stearate, Vegetable Cellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Dietary Supplement

Precautions

Disclaimer: Always consult with a qualified health physician before taking any new dietary supplement.

Warning: Keep out of the reach of children.

Do not take this or any other supplement if under the age of 18, pregnant or nursing a baby, or if you have any known or suspected medical conditions, and/or taking prescription drug(s) or OTC medication(s).

Do not take this or any other supplement if under the age of 18, pregnant or nursing a baby, or if you have any known or suspected medical conditions, and/or taking prescription drug(s) or OTC medication(s).

FDA Disclaimer Statement

This product is not intended to diagnose, treat, cure or prevent any diseases. These statements have not been evaluated by the Food & Drug Administration.

Storage

Storage: Store in a cool and dry place. Keep away from direct sunlight and heat.

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take 1-2 capsules daily.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Choline L-Bitartrate Capsules by Nootropics Depot label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Choline L-Bitartrate Capsules label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Choline L-Bitartrate Capsules by Nootropics Depot

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container15 Amounts shown are per serving.

Choline L-Bitartrate

Interacts with
16 drugs
500 mg per serving

Choline is an essential nutrient your body needs for liver function, brain health, and nerve signaling, and many people get enough from foods like egg...

Choline L-Bitartrate monograph & interactions

Other (inactive) ingredients: Silicon Dioxide, Magnesium Stearate, Vegetable Cellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Choline L-Bitartrate Capsules by Nootropics Depot Drug Interactions

Want to check YOUR meds against Choline L-Bitartrate Capsules?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
16Drugs
16 Minor

Ingredients driving the most interactions

Choline L-Bitartrate 16

Individual Drug Interactions

The ingredients in Choline L-Bitartrate Capsules interact with 16 drugs. Click any drug to see the details.

1 of the 1 ingredient in Choline L-Bitartrate Capsules interact with drugs. Each result below shows which ingredient is responsible. Choline L-Bitartrate

Each ingredient & the kinds of drugs it affects

For each ingredient in Choline L-Bitartrate Capsules with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Choline L-Bitartrate1 drug type · 16 drugs

Atropine

Theoretically, choline might decrease the effects of atropine in the brain.
Animal research shows that administering choline one hour before administering atropine can attenuate atropine-induced decreases in brain levels of acetylcholine. Theoretically, concomitant use of choline and atropine may decrease the effects of atropine.

Likelihood Possible Evidence D
Choline L-Bitartrate full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Choline L-Bitartrate Capsules, from the product label.

Nootropics Depot

See all Nootropics Depot products
Name
Nootropics Depot
Street Address
8380 S. Kyrene Rd. Ste. 110
City
Tempe
State
AZ
ZipCode
85284
Web Address
nootropicsdepot.com
Pharmacist Counseling Corner

Choline L-Bitartrate Capsules by Nootropics Depot: Common Questions

Does Choline L-Bitartrate Capsules by Nootropics Depot interact with any medications?
Yes. Based on its ingredients, Choline L-Bitartrate Capsules has a known interaction with 16 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Choline L-Bitartrate Capsules contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will choline help my memory or brain fog?
The evidence isn't established yet for age-related cognitive decline or Alzheimer disease. Choline does play a role in brain function, but we don't have reliable data showing this supplement works for those purposes. Your doctor can help you decide whether it's worth trying.
Is it safe if I'm pregnant or breastfeeding?
Choline is important during both pregnancy and breastfeeding, but the safety data advises using only prenatal or supplement doses your doctor recommends. Talk with your doctor or pharmacist before starting — they can advise you on the right amount for your situation.
What are the side effects at normal doses?
At typical doses, choline is well tolerated. Side effects mainly show up at high doses (9 grams daily or more) and include diarrhea, nausea, vomiting, and sweating. A fishy body odor can also occur at higher intakes.
How much choline is too much?
The daily upper limit is 3.5 grams. Doses above that — especially 9 grams daily or higher — can cause stomach upset and other side effects. Stick to the dose on the label unless your doctor tells you otherwise.
What does the 'L-bitartrate' part mean?
That's the form of choline used in this product. L-bitartrate is a salt (choline paired with tartaric acid) that helps your body absorb the choline. Different forms are absorbed differently, but this one is well tolerated.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Choline L-Bitartrate Capsules is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Choline L-Bitartrate Capsules label
Go deeper

The Full Monographs Behind Choline L-Bitartrate Capsules’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Choline

Interacts with 16 drugs

Choline is an essential nutrient your body needs for liver function, brain health, and nerve signaling, and many people get enough from foods like eggs, meat, and fish. Supplements may help...

Read the full Choline monograph →
Sources

Sources & How We Checked

Choline L-Bitartrate Capsules's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Choline 14 references
  1. Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
  2. Cho E, Willett WC, Colditz GA, et al. Dietary choline and betaine and the risk of distal colorectal adenoma in women. J Natl Cancer Inst 2007;99:1224-31. PubMed
  3. Schmidt, C., Abicht, A., Krampfl, K., Voss, W., Stucka, R., Mildner, G., Petrova, S., Schara, U., Mortier, W., Bufler, J., Huebner, A., and Lochmuller, H. Congenital myasthenic syndrome due to a novel missense mutation in the gene encoding choline acetyl
  4. Tamminga, C., Smith, R. C., Chang, S., Haraszti, J. S., and Davis, J. M. Depression associated with oral choline. Lancet 10-23-1976;2(7991):905. PubMed
  5. Wood, J. L. and Allison, R. G. Effects of consumption of choline and lecithin on neurological and cardiovascular systems. Fed.Proc. 1982;41(14):3015-3021.
  6. Growdon, J. H. and Gelenberg, A. J. Choline and lecithin administration to patients with tardive dyskinesia. Trans.Am.Neurol.Assoc. 1978;103:95-99.
  7. Smith, C. M., Swash, M., Exton-Smith, A. N., Phillips, M. J., Overstall, P. W., Piper, M. E., and Bailey, M. R. Choline therapy in Alzheimer's disease. Lancet 8-5-1978;2(8084):318. PubMed
  8. Morrison, L. M. and W. F. Gonzales. Choline in coronary atherosclerosis. Amer.Heart J. 1950;39:729.
  9. Christie, J. G. Blackburn 1. M. Glen A. I. M. Zeisel S. Shering A. & Yates C. M. Effects of choline and lecithin on CSF choline levels and on cognitive functioning in patients with presenile dementia of the Alzheimer type. Nutrition and the brain 1979;5
  10. Sidhu N, Davies S, Nadarajah A, et al. Oral choline supplementation for postoperative pain. Br J Anaesth 2013;111(2):249-55. PubMed
  11. Wozniak JR, Fuglestad AJ, Eckerle JK, et al. Choline supplementation in children with fetal alcohol spectrum disorders has high feasibility and tolerability. Nutr Res. 2013;33(11):897-904. PubMed
  12. Wozniak JR, Fuglestad AJ, Eckerle JK, et al. Choline supplementation in children with fetal alcohol disorders: a randomized, double-blind, placebo-controlled trial. Am J Clin Nutr. 2015;102(5): 1113-25.
  13. Ross RG, Hunter SK, McCarthy L, et al. Perinatal choline effects on neonatal pathophysiology related to later schizophrenia risk. Am J Psychiatry. 2013;170(3):290-8. PubMed
  14. Food and Nutrition Board, Institute of Medicine. Choline. Dietary Reference Intakes: Thiamin, Riboflavin, Niacin, Vitamin B-6, Vitamin B-12, Pantothenic Acid, Biotin, and Choline. Washington D.C.: National Academy Press; 1998:390-422.

See these in context on the Choline monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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