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Dietary supplement

Choline L-Bitartrate Powder 600 mg Ingredients & Drug Interactions

by BulkSupplements.com

Choline L-Bitartrate Powder 600 mg label
See full label image
Powder Category: Vitamin
Most serious interaction: Minor
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Choline L-Bitartrate Powder 600 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Minor

Choline L-Bitartrate Powder 600 mg is a dietary supplement by BulkSupplements.com with 1 active ingredient. Its ingredients are commonly taken for liver health and fatty liver, brain and memory support, prenatal nutrition and fetal development.Based on those ingredients, 16 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Choline L-Bitartrate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Choline L-Bitartrate Powder 600 mg by BulkSupplements.com

Ask about any prescription or over-the-counter medication and we check it for interactions with Choline L-Bitartrate Powder 600 mg by BulkSupplements.com — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Choline L-Bitartrate Powder 600 mg by BulkSupplements.com

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: choline L-bitartrate, a form of choline (an essential nutrient your body uses to build cell membranes and produce acetylcholine, a neurotransmitter important for brain and muscle function). Each serving delivers 600 mg of choline L-bitartrate.

Silica is included as an inactive ingredient.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Choline product and its label doesn't state a use — see Choline's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for choline L-bitartrate is mixed and often incomplete. For athletic performance, it appears to be possibly ineffective.

For bronchitis, age-related cognitive decline, liver problems related to parenteral nutrition (TPN-associated hepatic steatosis), allergic rhinitis (hay fever), and Alzheimer disease, there isn't enough reliable evidence to rate how well it works. If you're considering this supplement for a specific condition, talk with your pharmacist about what the current research actually shows.

The evidence, ingredient by ingredient Choline

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Choline is generally well tolerated when you take appropriate amounts. However, high doses — especially beyond the daily upper limit of 3.5 grams — can cause side effects.

At doses of 9 grams daily or higher, you may experience diarrhea, nausea, vomiting, salivation, sweating, and a fishy body odor (from intestinal breakdown of choline). Even higher doses (32 grams daily) have caused gastroenteritis.

Choline is important during pregnancy and breastfeeding, but use prenatal vitamins or supplement doses only as your doctor advises. The safety data rates choline as likely safe in pregnancy and lactation when used appropriately — don't self-dose without guidance.

Side effects, ingredient by ingredient Choline

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Choline.
  • The most serious interaction on file is rated Minor.
  • For scale: 16 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Minor interaction: atropine and related anticholinergic drugs. Choline may theoretically reduce their effects in the brain.

Check your exact medications with the tool on this page before you start.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Only minor medication interactions are documented, and safety information is well characterized.

Choline L-bitartrate may be worth considering if you're interested in supporting cell and brain function and your doctor confirms you need supplementation. If you take atropine or anticholinergic medications, check with us before starting.

Pregnant or breastfeeding — talk to your doctor first. For everyone else, chat with your pharmacist about your medications and whether this dose is right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 24, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Choline L-Bitartrate Powder 600 mg, straight from the product label.

Brand BulkSupplements.com
Barcode (UPC) X000TO33BL
Net contents 100 Gram(s); 3.5 Ounce(s)
Market status On market
Date entered into DSLD Apr 24, 2025
DSLD ID 330580
Product type Vitamin
Supplement form Powder
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Choline L-Bitartrate Powder 600 mg by BulkSupplements.com, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
600 Milligram(s)
Maximum serving Sizes:
600 Milligram(s)
Servings per container
167
UPC/BARCODE
X000TO33BL
IngredientAmount% DV
Choline L-Bitartrate600 mg--

Other ingredients: Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Choline L-Bitartrate Powder 600 mg per serving

Brand IP Statement(s)

BulkSupplements.com Clean & pure bulk supplements

FDA Disclaimer Statement

Warning: This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Always consult a physician before taking any dietary supplement.

Keep out of reach of children.

Formulation

Free Of: Added sugar, soy, dairy, yeast, gluten

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take 600 mg (about 1/4 tsp) once or twice daily with meal, or as directed by a physician.

Storage

Store in a dry, cool place Contents are sold by weight, not volume. Settling may occur.

General Statements

New Use an accurate milligram scale.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Choline L-Bitartrate Powder 600 mg by BulkSupplements.com label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Choline L-Bitartrate Powder 600 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Choline L-Bitartrate Powder 600 mg by BulkSupplements.com

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size600 Milligram(s) Dosage formPowder Servings per container167 Amounts shown are per serving.

Choline L-Bitartrate

Interacts with
16 drugs
600 mg per serving

Choline is an essential nutrient your body needs for liver function, brain health, and nerve signaling, and many people get enough from foods like egg...

Choline L-Bitartrate monograph & interactions

Other (inactive) ingredients: Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Choline L-Bitartrate Powder 600 mg by BulkSupplements.com Drug Interactions

Want to check YOUR meds against Choline L-Bitartrate Powder 600 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
16Drugs
16 Minor

Ingredients driving the most interactions

Choline L-Bitartrate 16

Individual Drug Interactions

The ingredients in Choline L-Bitartrate Powder 600 mg interact with 16 drugs. Click any drug to see the details.

1 of the 1 ingredient in Choline L-Bitartrate Powder 600 mg interact with drugs. Each result below shows which ingredient is responsible. Choline L-Bitartrate

Each ingredient & the kinds of drugs it affects

For each ingredient in Choline L-Bitartrate Powder 600 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Choline L-Bitartrate1 drug type · 16 drugs

Atropine

Theoretically, choline might decrease the effects of atropine in the brain.
Animal research shows that administering choline one hour before administering atropine can attenuate atropine-induced decreases in brain levels of acetylcholine. Theoretically, concomitant use of choline and atropine may decrease the effects of atropine.

Likelihood Possible Evidence D
Choline L-Bitartrate full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Choline L-Bitartrate Powder 600 mg, from the product label.

BulkSupplements.com

See all BulkSupplements.com products
Name
BulkSupplements.com
Street Address
7511 Eastgate Rd
City
Henderson
State
NV
ZipCode
89011
Web Address
BulkSupplements.com
Pharmacist Counseling Corner

Choline L-Bitartrate Powder 600 mg by BulkSupplements.com: Common Questions

Does Choline L-Bitartrate Powder 600 mg by BulkSupplements.com interact with any medications?
Yes. Based on its ingredients, Choline L-Bitartrate Powder 600 mg has a known interaction with 16 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Choline L-Bitartrate Powder 600 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe to take during pregnancy or while breastfeeding?
Choline is rated as likely safe in pregnancy and lactation, and it's actually important during both — but use only prenatal vitamins or supplements at doses your doctor advises. Don't self-dose. Talk with your doctor or pharmacist about what's right for you.
What's the difference between this and other choline products?
This product provides choline in the L-bitartrate form — a specific way the choline is bound to tartaric acid for absorption and stability. The choline itself does the work; the form is mainly about how your body takes it in. Your pharmacist can help you pick the form that fits your needs.
Can I take more than one serving a day?
The tolerable upper intake level for choline is 3.5 grams daily. Above that, side effects like nausea, vomiting, diarrhea, and a fishy body odor become more likely. Don't exceed that limit without talking to your pharmacist first.
Will this help me with memory or brain fog?
There isn't enough reliable evidence to rate how well choline works for age-related cognitive decline or Alzheimer disease. If you're hoping it'll sharpen your mind, the research doesn't firmly support that claim yet. Talk with your pharmacist about what might actually help.
What's that fishy smell some people report?
At high doses, choline can cause your body to produce a fishy odor because your gut bacteria break it down into trimethylamine. This is more common above the 3.5-gram daily limit. Staying within recommended amounts usually avoids it.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Choline L-Bitartrate Powder 600 mg label
Go deeper

The Full Monographs Behind Choline L-Bitartrate Powder 600 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Choline

Interacts with 16 drugs

Choline is an essential nutrient your body needs for liver function, brain health, and nerve signaling, and many people get enough from foods like eggs, meat, and fish. Supplements may help...

Read the full Choline monograph →
Sources

Sources & How We Checked

Choline L-Bitartrate Powder 600 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Choline 14 references
  1. Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
  2. Cho E, Willett WC, Colditz GA, et al. Dietary choline and betaine and the risk of distal colorectal adenoma in women. J Natl Cancer Inst 2007;99:1224-31. PubMed
  3. Schmidt, C., Abicht, A., Krampfl, K., Voss, W., Stucka, R., Mildner, G., Petrova, S., Schara, U., Mortier, W., Bufler, J., Huebner, A., and Lochmuller, H. Congenital myasthenic syndrome due to a novel missense mutation in the gene encoding choline acetyl
  4. Tamminga, C., Smith, R. C., Chang, S., Haraszti, J. S., and Davis, J. M. Depression associated with oral choline. Lancet 10-23-1976;2(7991):905. PubMed
  5. Wood, J. L. and Allison, R. G. Effects of consumption of choline and lecithin on neurological and cardiovascular systems. Fed.Proc. 1982;41(14):3015-3021.
  6. Growdon, J. H. and Gelenberg, A. J. Choline and lecithin administration to patients with tardive dyskinesia. Trans.Am.Neurol.Assoc. 1978;103:95-99.
  7. Smith, C. M., Swash, M., Exton-Smith, A. N., Phillips, M. J., Overstall, P. W., Piper, M. E., and Bailey, M. R. Choline therapy in Alzheimer's disease. Lancet 8-5-1978;2(8084):318. PubMed
  8. Morrison, L. M. and W. F. Gonzales. Choline in coronary atherosclerosis. Amer.Heart J. 1950;39:729.
  9. Christie, J. G. Blackburn 1. M. Glen A. I. M. Zeisel S. Shering A. & Yates C. M. Effects of choline and lecithin on CSF choline levels and on cognitive functioning in patients with presenile dementia of the Alzheimer type. Nutrition and the brain 1979;5
  10. Sidhu N, Davies S, Nadarajah A, et al. Oral choline supplementation for postoperative pain. Br J Anaesth 2013;111(2):249-55. PubMed
  11. Wozniak JR, Fuglestad AJ, Eckerle JK, et al. Choline supplementation in children with fetal alcohol spectrum disorders has high feasibility and tolerability. Nutr Res. 2013;33(11):897-904. PubMed
  12. Wozniak JR, Fuglestad AJ, Eckerle JK, et al. Choline supplementation in children with fetal alcohol disorders: a randomized, double-blind, placebo-controlled trial. Am J Clin Nutr. 2015;102(5): 1113-25.
  13. Ross RG, Hunter SK, McCarthy L, et al. Perinatal choline effects on neonatal pathophysiology related to later schizophrenia risk. Am J Psychiatry. 2013;170(3):290-8. PubMed
  14. Food and Nutrition Board, Institute of Medicine. Choline. Dietary Reference Intakes: Thiamin, Riboflavin, Niacin, Vitamin B-6, Vitamin B-12, Pantothenic Acid, Biotin, and Choline. Washington D.C.: National Academy Press; 1998:390-422.

See these in context on the Choline monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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