No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 1 of 3 ingredients. Check your meds →
Dietary supplement

Chondrinol Advanced 300 Ingredients & Drug Interactions

by Regenerative Tissue Science

Capsule Category: Other Combinations
No known interaction
The interaction bottom line No known interaction

Chondrinol Advanced 300 is a dietary supplement by Regenerative Tissue Science with 3 active ingredients. Its ingredients are commonly taken for skin hydration and aging, joint comfort and osteoarthritis, dry eyes.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Chondrinol Advanced 300 by Regenerative Tissue Science

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product has 3 active ingredients. Hyaluronic Acid is a naturally occurring compound in your body that helps retain moisture — it's used here to support skin and joint hydration.

The other two ingredients are Cyplexinol Pro Nature's BMP Complex and undenatured Collagen, which are included to support tissue health and structure. The capsule also contains gelatin and microcrystalline cellulose as inactive ingredients — these are the capsule shell and a binding agent.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Hyaluronic Acid's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: support healthy joint structure and function.
  • We looked for evidence on: Osteoarthritis, Exercise-induced muscle soreness, Wound healing, Joint cartilage health, Joint lubrication, Cartilage regeneration.
  • The closest evidence on file: Hyaluronic Acid is rated "Insufficient Reliable Evidence To Rate" for Exercise-induced muscle soreness (Natural Medicines).
  • Also on file: Hyaluronic Acid is rated "Insufficient Reliable Evidence To Rate" for Osteoarthritis, Wound healing.

Hyaluronic Acid is possibly effective for dry eye and for venous leg ulcers (slow-healing sores on the lower leg). For aging skin, hay fever, and sexual dysfunction, the evidence isn't established enough in our data to rate it.

We don't have effectiveness ratings in our data for Cyplexinol Pro Nature's BMP Complex or undenatured Collagen, so we can't speak to what evidence supports them.

The evidence, ingredient by ingredient Hyaluronic Acid

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Hyaluronic Acid taken by mouth appears to be well tolerated in most adults. That said, long-term safety data for supplements isn't fully studied, and the facts we hold advise caution about oral supplements — the recommendation is not to take oral hyaluronic acid unless your doctor recommends it.

We don't have safety information on file for Cyplexinol Pro Nature's BMP Complex or undenatured Collagen. Pregnancy and breastfeeding safety data aren't available for any of the ingredients in this product, so if you're pregnant, nursing, or planning either, talk with your doctor or pharmacist before starting.

Side effects, ingredient by ingredient Hyaluronic Acid

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. If you take any medications, use the search tool on this page or ask your pharmacist to be sure.

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.

Chondrinol Advanced 300 might appeal to you if you're interested in skin or joint support with hyaluronic acid. Because we can't check two of its three ingredients for interactions and the safety data on oral hyaluronic acid is limited, it's worth a quick conversation with your pharmacist before you start — especially if you're on other medications or have ongoing health conditions.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 22, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Chondrinol Advanced 300, straight from the product label.

Brand Regenerative Tissue Science
Net contents 30 Capsule(s)
Market status On market
Date entered into DSLD Mar 22, 2023
DSLD ID 275882
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Chondrinol Advanced 300 by Regenerative Tissue Science, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
3 Capsule(s)
Servings per container
30
IngredientAmount% DV
Hyaluronic Acid25 mg--
Cyplexinol Pro Nature's BMP Complex300 mg--
undenatured Collagen40 mg--

Other ingredients: Gelatin, Microcrystalline Cellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Chondrinol Advanced delivers triple-action nutrition to joints, helping to support the body's ability to grow new, healthy cartilage tissue, nourishing and lubricating joints, and supporting healthy immune signaling.

Non-GMO

Professional Grade Joint Support Multi Joint

Cyplexinol Pro is derived from a certified organic source.

Formula

Chondrinol Advanced 300 brings together the combined power of three premium nutritional ingredients in one supplement; Cyplexinol Pro, undenatured collagen, and hyaluronic acid.

Cyplexinol Pro Professional Grade Nature's BMP - Complex

Cyplexinol Pro plus collagen & hyaluronic acid

Suggested/Recommended/Usage/Directions

Suggested Dosage: As a supplement, take one (1) to three (3) capsules per day. For maximum joint support, take with Ostinol Advanced 5X.

Precautions

Warning: Consult with your healthcare provider before using this or any supplement if you are pregnant, nursing or on medication.

Do not use if inner seal is missing or broken.

Keep out of the reach of children.

Storage

Store in a cool, dry place.

Seals/Symbols

Made in USA

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

Patent Nos. 9,011,930 and 9,173,905

Regenerative Tissue Science, LLC Leaders in Natural Bio-Active Proteins A Subsidiary of ZyCal Bioceuticals Healthcare Company, Inc.

See for yourself

Chondrinol Advanced 300 by Regenerative Tissue Science label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Chondrinol Advanced 300 by Regenerative Tissue Science

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Hyaluronic Acid

No known
interactions
25 mg per serving

Hyaluronic acid is a natural substance in the body that helps hold water in the skin, joints, and eyes. Oral and topical products are popular for skin...

Hyaluronic Acid monograph & interactions

Cyplexinol Pro Nature's BMP Complex

300 mg per serving Form: Bone Morphogenetic Proteins, Collagen

Undenatured Collagen

40 mg per serving

Other (inactive) ingredients: Gelatin, Microcrystalline Cellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Chondrinol Advanced 300 by Regenerative Tissue Science Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Chondrinol Advanced 300. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Chondrinol Advanced 300, from the product label.

Regenerative Tissue Science

See all Regenerative Tissue Science products
Name
Regenerative Tissue Science, LLC.
Street Address
5 Executive Drive, Ste A
City
Toms River
State
NJ
ZipCode
08755
Phone Number
888-779-9225
Web Address
rts.ostinol.com
Pharmacist Counseling Corner

Chondrinol Advanced 300 by Regenerative Tissue Science: Common Questions

Does Chondrinol Advanced 300 by Regenerative Tissue Science interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Chondrinol Advanced 300. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Chondrinol Advanced 300 contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What does hyaluronic acid do in this product?
Hyaluronic acid is a natural substance that helps hold onto moisture. It's possibly effective for dry eye and for slow-healing sores on the lower leg. In a joint-support supplement like this one, it's meant to help keep your tissues hydrated.
Is hyaluronic acid safe to take by mouth?
Taken by mouth, hyaluronic acid appears to be well tolerated overall. The facts we hold do advise caution and note that it's best not to take oral hyaluronic acid unless your doctor recommends it, since long-term safety hasn't been fully studied.
Can I take this if I'm pregnant or breastfeeding?
We don't have pregnancy or breastfeeding safety data for any of the ingredients in this product. Talk with your doctor or pharmacist before you start if you're pregnant, nursing, or planning either.
What are the inactive ingredients?
The capsule is made of gelatin, and the powder inside contains microcrystalline cellulose as a binder. Both are common excipients.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Chondrinol Advanced 300 is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Chondrinol Advanced 300 label
Go deeper

The Full Monographs Behind Chondrinol Advanced 300’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Chondrinol Advanced 300's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Hyaluronic Acid 4 references
  1. Park Y, Song JS, Choi CY, Yoon KC, Lee HK, Kim HS. A randomized multicenter study comparing 0.1%, 0.15%, and 0.3% sodium hyaluronate with 0.05% cyclosporine in the treatment of dry eye. J Ocul Pharmacol Ther. 2017;33(2):66-72. PubMed
  2. U.S. Food and Drug Administration. Do Not Use Needle-Free Devices for Injection of Dermal Fillers - FDA Safety Communication. October 8, 2021. Available at: https://www.fda.gov/medical-devices/safety-communications/do-not-use-needle-free-devices-injection
  3. Disphanurat W, Srisantithum B. Efficacy and safety of 0.15% isobutylamido thiazolyl resorcinol combined with hyaluronic acid vs 0.15% isobutylamido thiazolyl resorcinol or hyaluronic acid alone in melasma treatment: A randomized evaluator-blind trial. J C PubMed
  4. Humbert P, Mikosinki J, Benchikhi H, Allaert FA. Efficacy and safety of a gauze pad containing hyaluronic acid in treatment of leg ulcers of venous or mixed origin: a double-blind, randomised, controlled trial. Int Wound J 2013;10(2):159-66. PubMed

See these in context on the Hyaluronic Acid monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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