Interactions on record — worth a quick check against your medications. Based on 3 of 5 ingredients. Check your meds →
Dietary supplement

Move Free Ultra with Type II Collagen Ingredients & Drug Interactions

by Schiff

Tablet Or Pill Category: Other Combinations
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Move Free Ultra with Type II Collagen is a dietary supplement by Schiff with 5 active ingredients. Its ingredients are commonly taken for skin hydration and aging, joint comfort and osteoarthritis, dry eyes.Based on those ingredients, 62 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Potassium Chloride. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Move Free Ultra with Type II Collagen by Schiff

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Partial disclosure
Ingredient Transparency · database check
Partial

Most active ingredients list an amount, but at least one is hidden in a blend or missing.

Why this rating?
  • The label discloses an exact amount for 3 of its 5 active ingredients.
  • “Cartilage Blend” is a proprietary blend — the label gives one combined amount (40 mg) without saying how much of each component you get.

Move Free Ultra contains 5 active ingredients aimed at joint and connective-tissue support. Undenatured Type II Collagen is the structural protein that makes up cartilage; Hyaluronic Acid is a natural compound that helps keep cartilage cushioned and skin hydrated; Boron Glycinate is a mineral form of boron; and Cartilage is animal-derived tissue.

The product also includes several inactive ingredients — cellulose, hydroxypropyl cellulose, croscarmellose sodium, silicon dioxide, coating, and magnesium stearate — which are fillers and binders that hold the tablet together.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: Joint, cartilage, and bone health.
  • We looked for evidence on: Osteoarthritis, Osteoporosis, Joint comfort, Cartilage support, Bone strength.
  • The closest evidence on file: Boron is rated "Insufficient Reliable Evidence To Rate" for Osteoporosis (Natural Medicines).
  • Also on file: Boron is rated "Insufficient Reliable Evidence To Rate" for Osteoarthritis.
  • Also on file: Hyaluronic Acid is rated "Insufficient Reliable Evidence To Rate" for Osteoarthritis.

The evidence for this product's ingredients is mixed. Hyaluronic Acid is possibly effective for dry eye and venous leg ulcers (persistent sores on the lower leg), but the data on it for aging skin, hay fever, and sexual dysfunction is too weak to rate.

Boron is likely effective for boron deficiency and possibly effective for vaginal yeast infections and radiation-damaged skin, but not for athletic performance. We hold no effectiveness data in our records for undenatured Type II Collagen or Cartilage, so their role in joint support isn't established in the evidence we have on file.

The evidence, ingredient by ingredient Hyaluronic Acid Boron Potassium

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Potassium chloride is generally well tolerated when taken at normal doses, with the most common side effects being stomach upset — abdominal pain, nausea, diarrhea, gas, or vomiting. At high levels, potassium can cause serious heart rhythm problems, low blood pressure, or mental confusion, which is why kidney disease or certain medications make it risky.

Boron is generally safe at low doses from food and supplements, but high doses can be toxic; if you're pregnant or breastfeeding, avoid boron supplements due to safety concerns. Hyaluronic Acid is generally well tolerated when taken by mouth or applied to skin, though topical use rarely causes eczema, redness, or itching.

We have no pregnancy or breastfeeding safety data on file for undenatured Type II Collagen or Cartilage.

Side effects, ingredient by ingredient Hyaluronic Acid Boron Potassium

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 3 matched ingredients can interact with medications — Potassium.
  • The most serious interaction on file is rated Moderate.
  • For scale: 62 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you're on potassium-sparing diuretics (like spironolactone), ACE inhibitors (like lisinopril), or angiotensin receptor blockers (like losartan) — all increase the risk of dangerously high blood potassium when combined with potassium supplements. Avoid this product if you have kidney disease or have been told to limit potassium intake.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glancePartially disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Move Free Ultra is aimed at people looking to support joint and cartilage health. If you take blood pressure medications — especially ACE inhibitors, ARBs, or potassium-sparing water pills — you should check with your doctor or pharmacist before starting this product, because the potassium content could raise your blood levels too high.

Talk with your own healthcare provider about whether this supplement fits your individual health picture and any medications you're on.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 22, 2016.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Move Free Ultra with Type II Collagen, straight from the product label.

Brand Schiff
Net contents 1 Coated Tablet(s)
Market status On market
Date entered into DSLD May 22, 2016
DSLD ID 59732
Product type Other Combinations
Supplement form Tablet Or Pill
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Move Free Ultra with Type II Collagen by Schiff, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
IngredientAmount% DV
undenatured Type II Collagen10 mg--
Hyaluronic Acid3.3 mg--
Boron Glycinate5 mg--
Potassium Chloride0 NP--
Cartilage0 NP--
Cartilage Blend40 mg--

Other ingredients: Cellulose, Hydroxypropyl Cellulose, Croscarmellose Sodium, Silicon Dioxide, Coating, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

FREE! SAMPLE PACK NOT FOR RETAIL SALE

JOINT CARTILAGE BONE

It promotes joint, cartilage, and bone health for more comfortable joint movement in just one tiny pill daily.

~ Helps preserve joints and maintain cartilage ~ Supports mobility, comfort, flexibility, and lubrication ~ Promotes bone health, critical for healthy joints

Undenatured Collagen from poultry source.

Brand IP Statement(s)

Since 1936

Keep moving all day with Move Free Ultra Triple Action.

2014 RB

UC-II is a registered trademark of InterHealth N.I. U.S. Patents 5,645,851, 5,637,321, 5,529,786, 5,750,144, 7,083,820, 7,846,487, EPO Patent EP1435906B1, U.S. and world-wide patents pending.

Suggested/Recommended/Usage/Directions

1 tiny pill daily

Directions: For best results take one (1) tablet daily.

Formula

WITH TYPE II COLLAGEN THE SAME PROTEIN IN HEALTHY CARTILAGE

FDA Statement of Identity

DIETARY SUPPLEMENT

Seals/Symbols

rb Reckitt Benckiser

UC-II

Precautions

Note: Not for use by pregnant or lactating women.

NOT SUITABLE FOR USE BY ANYONE UNDER THE AGE OF 18 YEARS OLD. KEEP OUT OF REACH OF CHILDREN.

Storage

STORE IN A COOL, DRY PLACE.

FDA Disclaimer Statement

THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION. THIS PRODUCT IS NOT INTENDED TO DIAGNOSE, TREAT, CURE OR PREVENT ANY DISEASE.

General

050514 8137556

See for yourself

Move Free Ultra with Type II Collagen by Schiff label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Move Free Ultra with Type II Collagen by Schiff

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Hyaluronic Acid

No known
interactions
3.3 mg per serving

Hyaluronic acid is a natural substance in the body that helps hold water in the skin, joints, and eyes. Oral and topical products are popular for skin...

Hyaluronic Acid monograph & interactions

Boron Glycinate

No known
interactions
5 mg per serving

Boron is a trace mineral found in many plant foods and sold as a supplement, mainly promoted for bone, joint, and hormone health. The human evidence f...

Boron Glycinate monograph & interactions

Cartilage Blend

40 mg per serving

Other (inactive) ingredients: Cellulose, Hydroxypropyl Cellulose, Croscarmellose Sodium, Silicon Dioxide, Coating, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Move Free Ultra with Type II Collagen by Schiff Drug Interactions

Want to check YOUR meds against Move Free Ultra with Type II Collagen?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
62Drugs
62 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Move Free Ultra with Type II Collagen with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Potassium Chloride3 drug types · 62 drugs

Ace Inhibitors (Aceis)

Using ACEIs with high doses of potassium increases the risk of hyperkalemia.
ACEIs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C
Angiotensin Receptor Blockers (Arbs)

Using ARBs with high doses of potassium increases the risk of hyperkalemia.
ARBs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C
Potassium-Sparing Diuretics

Concomitant use increases the risk of hyperkalemia.
Using potassium-sparing diuretics with potassium supplements increases the risk of hyperkalemia.

Likelihood Likely Evidence C
The maker

Brand information

Manufacturer and brand details for Move Free Ultra with Type II Collagen, from the product label.

Schiff

See all Schiff products
Name
Reckitt Benckiser
City
Parsippany
State
NJ
ZipCode
07054-0224
Phone Number
1-800-526-6251
Web Address
www.movefree.com
Pharmacist Counseling Corner

Move Free Ultra with Type II Collagen by Schiff: Common Questions

Does Move Free Ultra with Type II Collagen by Schiff interact with any medications?
Yes. Based on its ingredients, Move Free Ultra with Type II Collagen has a known interaction with 62 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Move Free Ultra with Type II Collagen contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help my joint pain or cartilage?
The ingredients are designed to support joint and cartilage health, but our data doesn't have strong evidence that undenatured Type II Collagen or Cartilage themselves work for that purpose. Hyaluronic Acid has possibly effective evidence for a few conditions but not specifically for joints. Talk with your doctor about whether this fits your needs.
Is this safe if I'm pregnant or breastfeeding?
Boron Glycinate should be avoided during pregnancy and breastfeeding — the safety data advises against it. Potassium is likely safe, but use supplements only under your doctor's guidance. We don't have enough data on the collagen and cartilage ingredients to know either way, so discuss it with your doctor or pharmacist for personalized advice.
What are the most common side effects?
Potassium can cause stomach upset — nausea, diarrhea, gas, or abdominal pain. Boron at normal doses is generally well tolerated. Hyaluronic Acid appears well tolerated when taken by mouth.
Can I take this if I have high blood pressure?
It depends on which blood pressure medication you take. If you're on an ACE inhibitor, ARB, or potassium-sparing diuretic, the potassium in this product could raise your blood levels too high and cause heart rhythm problems. Check with your doctor before starting.
Does this product have fillers?
Yes. It contains inactive ingredients including cellulose, hydroxypropyl cellulose, croscarmellose sodium, silicon dioxide, a coating, and magnesium stearate — these help hold the tablet together but aren't active ingredients.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Move Free Ultra with Type II Collagen is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Move Free Ultra with Type II Collagen label
Sources

Sources & How We Checked

Move Free Ultra with Type II Collagen's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 22 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Hyaluronic Acid 4 references
  1. Park Y, Song JS, Choi CY, Yoon KC, Lee HK, Kim HS. A randomized multicenter study comparing 0.1%, 0.15%, and 0.3% sodium hyaluronate with 0.05% cyclosporine in the treatment of dry eye. J Ocul Pharmacol Ther. 2017;33(2):66-72. PubMed
  2. U.S. Food and Drug Administration. Do Not Use Needle-Free Devices for Injection of Dermal Fillers - FDA Safety Communication. October 8, 2021. Available at: https://www.fda.gov/medical-devices/safety-communications/do-not-use-needle-free-devices-injection
  3. Disphanurat W, Srisantithum B. Efficacy and safety of 0.15% isobutylamido thiazolyl resorcinol combined with hyaluronic acid vs 0.15% isobutylamido thiazolyl resorcinol or hyaluronic acid alone in melasma treatment: A randomized evaluator-blind trial. J C PubMed
  4. Humbert P, Mikosinki J, Benchikhi H, Allaert FA. Efficacy and safety of a gauze pad containing hyaluronic acid in treatment of leg ulcers of venous or mixed origin: a double-blind, randomised, controlled trial. Int Wound J 2013;10(2):159-66. PubMed

See these in context on the Hyaluronic Acid monograph →

Boron 6 references
  1. Ellenhorn MJ, et al. Ellenhorn's Medical Toxicology: Diagnoses and Treatment of Human Poisoning. 2nd ed. Baltimore, MD: Williams & Wilkins, 1997.
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  3. Thai L, Hart LL. Boric acid vaginal suppositories. Ann Pharmacother 1993;27:1355-7.
  4. Acs N, Banhidy F, Puho E, Czeizel AE. Teratogenic effects of vaginal boric acid treatment during pregnancy. Int J Gynaecol Obstet 2006;93:55-6. PubMed
  5. Garabrant, D. H., Bernstein, L., Peters, J. M., and Smith, T. J. Respiratory and eye irritation from boron oxide and boric acid dusts. J Occup Med 1984;26(8):584-586. PubMed
  6. Hjelm C, Harari F, Vahter M. Pre- and postnatal environmental boron exposure and infant growth: results from a mother-child cohort in northern Argentina. Environ Res 2019;171:60-8. PubMed

See these in context on the Boron monograph →

Potassium 12 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Gennaro A. Remington: The Science and Practice of Pharmacy. 19th ed. Lippincott: Williams & Wilkins, 1996.
  3. Whelton PK, He J, Cutler JA, et al. Effects of oral potassium on blood pressure. Meta-analysis of randomized controlled clinical trials. JAMA 1997;277:1624-32. PubMed
  4. Phillips, C. O., Kashani, A., Ko, D. K., Francis, G., and Krumholz, H. M. Adverse effects of combination angiotensin II receptor blockers plus angiotensin-converting enzyme inhibitors for left ventricular dysfunction: a quantitative review of data from ra DOI
  5. Altieri, P. I., Herrero, C., Suero, R., and Ortiz, A. Bleeding duodenal ulcer in a patient taking slow-releasing potassium tablets. Bol.Asoc.Med P.R. 1977;69(8):276.
  6. Raf, L. E. Enteric-coated potassium chloride tablets and ulcer of the small intestine. Acta Chir Scand Suppl 1967;(374):1-87.
  7. Potassium chloride oral solution [package insert]. Allentown, PA: Lehigh Valley Technologies, Inc.; 2014.
  8. Potassium chloride injection [package insert]. Lake Forest, IL: Hospira Inc.; 2009.
  9. Patel RB, Tannenbaum S, Viana-Tejedor A, et al. Serum potassium levels, cardiac arrhythmias, and mortality following non-ST-elevation myocardial infarction or unstable angina: insights from MERLIN-TIMI 36. Eur Heart J Acute Cardiovasc Care 2017 Feb;6(1):1 PubMed
  10. Malta D, Arcand J, Ravindran A, Floras V, Allard JP, Newton GE. Adequate intake of potassium does not cause hyperkalemia in hypertensive individuals taking medications that antagonize the renin angiotensin aldosterone system. Am J Clin Nutr 2016 Oct;104(4 PubMed
  11. Keskin M, Kaya A, Tatlisu MA, et al. The effect of serum potassium level on in-hospital and long-term mortality in ST elevation myocardial infarction. Int J cardiol. 2016 Oct 15;221:505-10.
  12. Stallings VA, Harrison M, Oria M; Committee to Review the Dietary Reference Intakes for Sodium and Potassium, Food and Nutrition Board, Health and Medicine Division, National Academies of Sciences, Engineering, and Medicine. Washington (DC): National Acad

See these in context on the Potassium monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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