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Dietary supplement

Cilantro Ingredients & Drug Interactions

by Herbalist & Alchemist

Liquid Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Cilantro is a dietary supplement by Herbalist & Alchemist with 1 active ingredient. Its ingredients are commonly taken for digestive upset and gas, appetite stimulation, mild antimicrobial (topical).Based on those ingredients, 717 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are fresh Cilantro herb extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Cilantro by Herbalist & Alchemist

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: fresh cilantro herb extract. The liquid is preserved with distilled water and ethyl alcohol as inactive ingredients.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Coriander product and its label doesn't state a use — see Coriander's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence we hold doesn't establish that cilantro is effective for any condition. For the uses tracked in our data — anorexia, anxiety, constipation, diabetes, diarrhea, and indigestion — the evidence is insufficient to rate.

That doesn't mean it doesn't work; it means the clinical research backing these uses isn't yet solid enough for us to vouch for it.

The evidence, ingredient by ingredient Coriander

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Cilantro is generally well tolerated in the amounts you'd eat as a food or spice. At medicinal doses in concentrated form, safety data is limited, so use caution and talk with your doctor or pharmacist before starting.

Rare but serious allergic reactions — including anaphylaxis (a severe, whole-body reaction) — have been reported, particularly in people sensitized through occupational exposure to cilantro dust or powder. Topical application can cause contact dermatitis, itching, or a burning sensation in sensitive individuals.

If you have a known spice allergy or suspect you might be sensitive to cilantro, be cautious.

Side effects, ingredient by ingredient Coriander

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Coriander.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 717 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you take antidiabetes drugs (risk of low blood sugar), antihypertensive drugs (risk of excessively low blood pressure), central nervous system depressants like sedatives, or photosensitizing drugs. All of these carry Moderate interaction severity.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Cilantro extract is generally well tolerated but comes with Moderate interactions involving blood sugar, blood pressure, and sedative medications. If you're on any of those drug types, check your specific medications with the tool on this page before starting, and talk it over with your doctor or pharmacist.

Anyone with a spice allergy should be especially careful.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 23, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Cilantro, straight from the product label.

Brand Herbalist & Alchemist
Barcode (UPC) 667056132217
Net contents 2 fl. Oz.; 60 mL
Market status On market
Date entered into DSLD Mar 23, 2018
DSLD ID 173864
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Kosher, Organic
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Cilantro by Herbalist & Alchemist, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 mL
Maximum serving Sizes:
3 mL
Servings per container
20
UPC/BARCODE
667056132217
IngredientAmount% DV
fresh Cilantro herb extract3 mL--

Other ingredients: distilled Water, Ethyl Alcohol

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Coriandrum sativum

OK

FDA Statement of Identity

Herbal Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: 40-60 drops (2-3 mL) in juice or water. Take 3 times per day. Shake well before using.

General Statements

Botanical preparation ratio 1:1.5

Precautions

Keep out of children's reach

FDA Disclaimer Statement

This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

General

NO. CIL-2 1733WE

Seals/Symbols

OK

See for yourself

Cilantro by Herbalist & Alchemist label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Cilantro by Herbalist & Alchemist

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 mL Dosage formLiquid Servings per container20 Amounts shown are per serving.

Fresh Cilantro herb extract

Interacts with
717 drugs
3 mL per serving

Coriander (also called cilantro) is a common cooking herb and spice that has long been used in traditional medicine for digestive complaints. As a foo...

Fresh Cilantro herb extract monograph & interactions

Other (inactive) ingredients: Distilled Water, Ethyl Alcohol. These complete the product’s ingredient list but are not active constituents.

Interaction report

Cilantro by Herbalist & Alchemist Drug Interactions

Want to check YOUR meds against Cilantro?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
717Drugs
717 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Cilantro with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

fresh Cilantro herb extract4 drug types · 717 drugs

Antidiabetes Drugs

Theoretically, coriander might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Evidence from animal research suggests that coriander fruit and coriander extract can reduce blood glucose levels. Monitor blood glucose levels closely. Dose adjustments might be necessary.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, coriander might increase the risk of hypotension when taken with antihypertensive drugs.
Evidence from animal research suggests that coriander fruit can lower blood pressure.

Likelihood Possible Evidence D
Cns Depressants

Theoretically, coriander might cause additive sedative effects when taken with CNS depressants.
Evidence from animal research suggests that coriander fruit extract has sedative effects.

Likelihood Possible Evidence D
Photosensitizing Drugs

Theoretically, coriander might increase the risk of photosensitivity when taken with photosensitizing drugs.
Evidence from in vitro research suggests that coriandrin, a constituent of coriander, has photosensitizing effects.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Cilantro, from the product label.

Herbalist & Alchemist

See all Herbalist & Alchemist products
Name
Herbalist & Alchemist, Inc.
City
Washington
State
NJ
ZipCode
07882
Phone Number
800-611-8235
Web Address
www.herbalist-alchemist.com
Pharmacist Counseling Corner

Cilantro by Herbalist & Alchemist: Common Questions

Does Cilantro by Herbalist & Alchemist interact with any medications?
Yes. Based on its ingredients, Cilantro has a known interaction with 717 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Cilantro contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take cilantro extract if I'm on diabetes medication?
Animal research suggests cilantro can lower blood glucose, so there's a theoretical risk it could increase low blood sugar (hypoglycemia) if combined with diabetes drugs. Check your specific medication with your doctor or pharmacist, and if you do take them together, monitor your blood sugar closely — your dose might need adjusting.
Is cilantro safe for everyone?
Most people tolerate it well, especially at food amounts. But rare allergic reactions, including severe anaphylaxis, have been reported — especially in people sensitized through work with cilantro dust. If you have a spice allergy, talk with your pharmacist before trying this product.
What's actually in this product?
It's a liquid extract of fresh cilantro herb preserved with water and ethyl alcohol. There are no other active ingredients.
Does cilantro really help with digestion or anxiety?
The evidence we have isn't reliable enough yet to say whether it works for those purposes. If you're interested in trying it for a specific reason, talk with your doctor or pharmacist to see if it makes sense for you.
What side effects should I watch for?
Most people don't report side effects. Topical use can cause itching or a burning sensation in sensitive skin. Oral use is rare but can trigger severe allergic reactions in people sensitized to cilantro — if you experience trouble breathing, swelling, or hives, seek immediate help.
Can I take this while pregnant or breastfeeding?
We don't have safety data on file for cilantro in pregnancy or lactation. Talk with your doctor or pharmacist about whether it's right for you during this time — they can give you personalized advice.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Cilantro is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Cilantro label
Sources

Sources & How We Checked

Cilantro's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Coriander 12 references
  1. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  2. Swanston-Flatt SK, Day C, Bailey CJ, Flatt PR. Traditional plant treatments for diabetes. Studies in normal and streptozotocin diabetic mice. Diabetologia 1990;33:462-4. PubMed
  3. Gray, A. M. and Flatt, P. R. Insulin-releasing and insulin-like activity of the traditional anti-diabetic plant Coriandrum sativum (coriander). Br.J Nutr. 1999;81(3):203-209.
  4. Kanerva, L. and Soini, M. Occupational protein contact dermatitis from coriander. Contact Dermatitis 2001;45(6):354-355. PubMed
  5. Emamghoreishi, M., Khasaki, M., and Aazam, M. F. Coriandrum sativum: evaluation of its anxiolytic effect in the elevated plus-maze. J Ethnopharmacol. 1-15-2005;96(3):365-370. PubMed
  6. Ebo, D. G., Bridts, C. H., Mertens, M. H., and Stevens, W. J. Coriander anaphylaxis in a spice grinder with undetected occupational allergy. Acta Clin Belg. 2006;61(3):152-156. PubMed
  7. Eidi, M., Eidi, A., Saeidi, A., Molanaei, S., Sadeghipour, A., Bahar, M., and Bahar, K. Effect of coriander seed (Coriandrum sativum L.) ethanol extract on insulin release from pancreatic beta cells in streptozotocin-induced diabetic rats. Phytother.Res
  8. Jabeen, Q., Bashir, S., Lyoussi, B., and Gilani, A. H. Coriander fruit exhibits gut modulatory, blood pressure lowering and diuretic activities. J Ethnopharmacol. 2-25-2009;122(1):123-130. PubMed
  9. van Toorenenbergen, A. W. and Dieges, P. H. Immunoglobulin E antibodies against coriander and other spices. J Allergy Clin Immunol. 1985;76(3):477-481. PubMed
  10. Ashwood-Smith, M. J., Warrington, P. J., Jenkins, M., Ceska, O., and Romaniuk, P. J. Photobiological properties of a novel, naturally occurring furoisocoumarin, coriandrin. Photochem.Photobiol. 1989;50(6):745-751. PubMed
  11. Sastre, J., Olmo, M., Novalvos, A., Ibanez, D., and Lahoz, C. Occupational asthma due to different spices. Allergy 1996;51(2):117-120. PubMed
  12. Beikert FC, Anastasiadou Z, Fritzen B, Frank U, Augustin M. Topical treatment of tinea pedis using 6% coriander oil in unguentum leniens: a randomized, controlled, comparative pilot study. Dermatology. 2013;226(1):47-51. PubMed

See these in context on the Coriander monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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