Cinnamon Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Cinnamon against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Cinnamon is a dietary supplement by Herbalist & Alchemist with 1 active ingredient. Its ingredients are commonly taken for blood sugar support, digestive upset, antioxidant support.Based on those ingredients, 442 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are dried Cinnamon bark extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Cinnamon by Herbalist & Alchemist
Ask about any prescription or over-the-counter medication and we check it for interactions with Cinnamon by Herbalist & Alchemist — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Cinnamon by Herbalist & Alchemist
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: dried cinnamon bark extract. It's prepared as a liquid using ethyl alcohol, distilled water, and vegetable glycerin as inactive ingredients to deliver the extract.
Does it work?
Not established
The evidence we hold doesn't establish that cinnamon works for the conditions listed on this product—including amenorrhea (absent periods), angina, common cold, diabetes, diarrhea, and high cholesterol (dyslipidemia). For all of these, the data available shows insufficient reliable evidence to rate it either way.
If you're considering this for a specific health goal, talk with your pharmacist or doctor about what the current research actually supports.
How safe is it?
Well-documented data
Cinnamon is generally well tolerated in the amounts we eat in food. At supplement doses—especially higher or long-term doses—the coumarin in cinnamon bark raises concerns about liver damage over time.
Food amounts are likely fine during pregnancy and breastfeeding, but avoid medicinal or concentrated supplement doses in these situations without talking to your doctor first. We also don't have enough safety data on concentrated supplement forms during breastfeeding to say either way.
In clinical trials, side effects were rare. One person developed a rash at 1 gram daily, and one person (with a known cinnamon allergy) had eyelid swelling from dietary cinnamon that cleared five days after stopping it.
One person taking 1 gram daily had a low blood sugar seizure, though it's unclear if cinnamon caused it.
Meds to double-check
Moderate interaction found
Before you take this product, check any diabetes medications (your blood sugar might drop further) and any drugs that can harm the liver, especially at higher doses or over long stretches. No other interactions are documented in our data for this ingredient.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.
This cinnamon extract might interest you if you want to try it for general wellness, but the evidence for specific health claims isn't established in our data. Be careful if you take diabetes medications or drugs that stress the liver—check your exact medications with the tool on this page.
Talk to your pharmacist before starting, especially if you're pregnant, breastfeeding, or on long-term medications.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 23, 2019.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Cinnamon, straight from the product label.
| Brand | Herbalist & Alchemist |
|---|---|
| Barcode (UPC) | 667056108755 |
| Net contents | 2 fl. Oz.; 60 mL |
| Market status | On market |
| Date entered into DSLD | Oct 23, 2019 |
| DSLD ID | 208707 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Kosher, Women (not pregnant or lactating) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Cinnamon by Herbalist & Alchemist, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| dried Cinnamon bark extract | 2 mL | -- |
Other ingredients: Ethyl Alcohol, distilled Water, Vegetable Glycerin
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
Cinnamomum verum
OK
General Statements
Supports peripheral circulation
Botanical preparation ratio 1:4
FDA Statement of Identity
Herbal Supplement
Suggested/Recommended/Usage/Directions
Suggested use: 20-40 drops (1-2 mL) in juice or water. Take 4 times per day. Shake well before using.
Precautions
Contraindications: Do not use during pregnancy unless otherwise directed by a qualified expert.
Keep out of children's reach
FDA Disclaimer Statement
This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
Seals/Symbols
OK
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Cinnamon by Herbalist & Alchemist label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Cinnamon by Herbalist & Alchemist
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 mL Dosage formLiquid Servings per container30 Amounts shown are per serving.
Dried Cinnamon bark extract
Interacts with442 drugs
Cassia cinnamon is the common, inexpensive cinnamon used in cooking, and it is also taken as a supplement, most often for blood sugar support. The evi...
Dried Cinnamon bark extract monograph & interactionsOther (inactive) ingredients: Ethyl Alcohol, Distilled Water, Vegetable Glycerin. These complete the product’s ingredient list but are not active constituents.
Cinnamon by Herbalist & Alchemist Drug Interactions
HelloPharmacist Interaction Report
Herbalist & Alchemist Cinnamon is a single-ingredient liquid extract of dried cinnamon bark.
It does interact with two important medication categories, both at Moderate severity.
Read the full breakdown — every affected drug type, severity by severity
The main concern is with drugs that stress the liver (hepatotoxic drugs). In theory, large doses of this cinnamon product could add to that stress over time.
Cinnamon bark contains coumarin, a compound that can damage the liver in animal studies. In humans, very high doses of coumarin (50 to 7,000 mg per day) have caused liver damage that went away once the coumarin stopped.
In clinical trials, people took 360 mg to 12 grams of cinnamon daily for three months without significant changes to liver enzymes—but the safety data is limited for long-term or very high-dose use.
The second category is diabetes medications (antidiabetes drugs). Cassia cinnamon may lower blood sugar on its own, so it could add to the effect of your diabetes medication.
If you're on insulin or other blood-sugar-lowering drugs, your dose might need adjustment.
Altogether, these interactions span 425 individual medications. Use the medication checker on this page to look up your specific drugs before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Cinnamon?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Cinnamon interact with 442 drugs. Click any drug to see the details.
1 of the 1 ingredient in Cinnamon interact with drugs. Each result below shows which ingredient is responsible. dried Cinnamon bark extract
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Dried Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Dried Cinnamon Bark Extract + 6-mercaptopurine interactionAbacavir Sulfate, Dolutegravir, LamivudineTriumeq
How Abacavir Sulfate, Dolutegravir, Lamivudine interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Dried Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Dried Cinnamon Bark Extract + Abacavir Sulfate, Dolutegravir, Lamivudine interactionAbacavir, LamivudineEpzicom
How Abacavir, Lamivudine interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Dried Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Dried Cinnamon Bark Extract + Abacavir, Lamivudine interactionAbiraterone
How Abiraterone interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Dried Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Dried Cinnamon Bark Extract + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Dried Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Dried Cinnamon Bark Extract + Abiraterone Acetate interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Dried Cinnamon Bark ExtractAntidiabetes Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, cassia cinnamon may have additive effects with antidiabetes drugs.
Read the full Dried Cinnamon Bark Extract + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Dried Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Dried Cinnamon Bark Extract + Acebutolol interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Dried Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Dried Cinnamon Bark Extract + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Dried Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Dried Cinnamon Bark Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Dried Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Dried Cinnamon Bark Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Dried Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Dried Cinnamon Bark Extract + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Dried Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Dried Cinnamon Bark Extract + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Dried Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Dried Cinnamon Bark Extract + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Dried Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Dried Cinnamon Bark Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Dried Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Dried Cinnamon Bark Extract + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Dried Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Dried Cinnamon Bark Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Dried Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Dried Cinnamon Bark Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Dried Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Dried Cinnamon Bark Extract + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Dried Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Dried Cinnamon Bark Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Dried Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Dried Cinnamon Bark Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Dried Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Dried Cinnamon Bark Extract + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Dried Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Dried Cinnamon Bark Extract + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Dried Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Dried Cinnamon Bark Extract + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Dried Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Dried Cinnamon Bark Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Dried Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Dried Cinnamon Bark Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Dried Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Dried Cinnamon Bark Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Dried Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Dried Cinnamon Bark Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Dried Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Dried Cinnamon Bark Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Dried Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Dried Cinnamon Bark Extract + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylephrineAlka-Seltzer PLUS, Histex SR, Protid
How Acetaminophen, Chlorpheniramine, Phenylephrine interacts with Cinnamon — through 1 ingredient. Tap an ingredient for the detail:
Dried Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Dried Cinnamon Bark Extract + Acetaminophen, Chlorpheniramine, Phenylephrine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Cinnamon with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
dried Cinnamon bark extract
Antidiabetes Drugs
Theoretically, cassia cinnamon may have additive effects with antidiabetes drugs.
Cassia cinnamon may lower blood glucose levels, and have additive effects in patients treated with antidiabetic agents. Dose adjustments to diabetes medications might be necessary.
Hepatotoxic Drugs
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
There is some concern that ingesting large amounts of cassia cinnamon for an extended duration might cause hepatotoxicity in some people. Cassia cinnamon contains coumarin, which can cause hepatotoxicity in animal models. In humans, very high doses of coumarin from 50-7000 mg/day can result in hepatotoxicity that resolves when coumarin use is discontinued. Lower amounts might also cause liver problems in sensitive people, such as those with liver disease or those taking potentially hepatotoxic agents.
Brand information
Manufacturer and brand details for Cinnamon, from the product label.
Herbalist & Alchemist
See all Herbalist & Alchemist products- Name
- Herbalist & Alchemist, Inc.
- City
- Washington
- State
- NJ
- ZipCode
- 07882
- Phone Number
- 800-611-8235
- Web Address
- www.herbalist-alchemist.com
Cinnamon by Herbalist & Alchemist: Common Questions
Does Cinnamon by Herbalist & Alchemist interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is cinnamon safe during pregnancy and breastfeeding?
What does this extract actually do?
Are there side effects I should know about?
Is this safe if I'm on a diabetes medication?
Can it harm my liver?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Cinnamon is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Cinnamon’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Cinnamon's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 20 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Cassia Cinnamon 20 references
- Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
- Khan A, Safdar M, Ali Khan M, et al. Cinnamon improves glucose and lipids of people with type 2 diabetes. Diabetes Care 2003;26:3215-8. PubMed
- De Benito V, Alzaga R. Occupational allergic contact dermatitis from cassia (Chinese cinnamon) as a flavouring agent in coffee. Contact Dermatitis 1999;40:165. PubMed
- Drake TE, Maibach HI. Allergic contact dermatitis and stomatitis caused by a cinnamic aldehyde-flavored toothpaste. Arch Dermatol 1976;112:202-3.
- Press release. Cinnamon capsules to reduce blood sugar are medicinal products! Efficacy has not been scientifically proven - some products contain high levels of coumarin. Federal Institute of Risk Assessment (BfM), Germany, November 11, 2006. Available a
- Felter SP, Vassallo JD, Carlton BD, Daston GP. A safety assessment of coumarin taking into account species-specificity of toxicokinetics. Food Chem Toxicol 2006;44:462-75. PubMed
- Crawford P. Effectiveness of cinnamon for lowering hemoglobin A1C in patients with type 2 diabetes: a randomized, controlled trial. J Am Board Fam Med 2009;22:507-12. PubMed
- Akilen, R., Tsiami, A., Devendra, D., and Robinson, N. Glycated haemoglobin and blood pressure-lowering effect of cinnamon in multi-ethnic Type 2 diabetic patients in the UK: a randomized, placebo-controlled, double-blind clinical trial. Diabet.Med. 2010; PubMed
- Lu T, Sheng H Wu J Cheng Y Zhu J Chen Y. Cinnamon extract improves fasting blood glucose and glycosylated hemoglobin level in Chinese patients with type 2 diabetes. Nutr Res. 2012;32(6):408-412. PubMed
- Choi, J., Lee, K. T., Ka, H., Jung, W. T., Jung, H. J., and Park, H. J. Constituents of the essential oil of the Cinnamomum cassia stem bark and the biological properties. Arch Pharm Res 2001;24(5):418-423.
- Altschuler JA, Casella SJ, MacKenzie TA, Curtis KM. The effect of cinnamon on A1C among adolescents with type 1 diabetes. Diabetes Care 2007;30(4):813-6. PubMed
- Stoecker BR, Zhan Z, Luo R, et al. Cinnamon extract lowers blood glucose in hyperglycemic subjects. FASEB J. 2010;22:722.1 (Abstract only). DOI
- Admani S, Hill H, Jacob SE. Cinnamon Sugar Scrub Dermatitis: "Natural" Is Not Always Best. Pediatr Dermatol. 2017;34(1):e42-e43. PubMed
- Isaac-Renton M, Li MK, Parsons LM. Cinnamon spice and everything not nice: many features of intraoral allergy to cinnamic aldehyde. Dermatitis. 2015;26(3):116-21. PubMed
- Vandersall A, Katta R. Eyelid dermatitis as a manifestation of systemic contact dermatitis to cinnamon. Dermatitis. 2015 Jul-Aug;26(4):189. PubMed
- Wickenberg J, Lindstedt S, Nilsson J, Hlebowicz J. Cassia cinnamon does not change the insulin sensitivity or the liver enzymes in subjects with impaired glucose tolerance. Nutr J 2014 Sep 24;13:96. PubMed
- Brancheau D, Patel B, Zughaib M. Do cinnamon supplements cause acute hepatitis? Am J Case Rep 2015;16:250-4. PubMed
- Shekarchizadeh-Esfahani P, Heydarpour F, Izadi F, Jalili C. The effect of cinnamon supplementation on liver enzymes in adults: A systematic review and meta-analysis of randomized controlled trials. Complement Ther Med 2021;58:102699. PubMed
- Bernaola J, Valverde-Monge M, Otal-Buesa M, Cullen D, Heras-Mendaza F. Cinnamon allergic contact cheilitis. Contact Dermatitis 2023;88(5):418-419. PubMed
- Patel K, Howard M, Tate B. Cheilitis caused by allergic contact dermatitis to cinnamon in chai tea: A case report. Contact Dermatitis 2023;88(3):239-240. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC