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Dietary supplement

Cilantrol Ingredients & Drug Interactions

by North American Herb & Spice

Cilantrol label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Cilantrol against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Cilantrol is a dietary supplement by North American Herb & Spice with 1 active ingredient. Its ingredients are commonly taken for digestive upset and gas, appetite stimulation, mild antimicrobial (topical).Based on those ingredients, 717 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Coriander Seed Oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Cilantrol by North American Herb & Spice

Ask about any prescription or over-the-counter medication and we check it for interactions with Cilantrol by North American Herb & Spice — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Cilantrol by North American Herb & Spice

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 1 active ingredient.
  • “Proprietary Blend” is a proprietary blend — the label doesn't break down how much of each component you get.

Cilantrol contains one active ingredient: coriander seed oil, derived from coriander fruit. The product has no inactive ingredients listed — it's the oil itself.

Coriander is a culinary spice traditionally used in herbal medicine, though the concentrated oil form is much more potent than the amounts you'd use in cooking.

Does it work?

No specific claim
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
General wellness

This Coriander product is marketed for general wellness, not a specific health condition, so there's no single claim to grade — see Coriander's own graded uses on its monograph.

Why this rating?
  • The label markets general wellness (“digestive health and detoxification support”), not a specific health condition, so there is no single claim to grade against clinical-evidence data.

The evidence for coriander's effectiveness is limited. The product facts show insufficient reliable evidence to rate coriander for anorexia, anxiety, constipation, diabetes, diarrhea, or dyspepsia — the conditions most commonly associated with it.

That means the science hasn't yet established whether it actually works for these purposes, so we can't make a claim about its benefit.

The evidence, ingredient by ingredient Coriander

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Coriander is generally well tolerated when used in normal food amounts. Concentrated medicinal doses or essential oil — like this product — lack solid safety data, so use caution and talk it over with your doctor or pharmacist first.

The most common side effect is contact dermatitis (skin irritation) from topical use; orally, coriander is generally well tolerated, though a rare but serious allergic reaction called anaphylaxis has been reported in sensitive individuals, including symptoms like hives, throat swelling, and trouble breathing.

Side effects, ingredient by ingredient Coriander

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Coriander.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 717 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Cilantrol, double-check your medications against this list with your pharmacist or doctor. The most important concern is diabetes medication — coriander can lower blood sugar.

You should also verify blood pressure medications, sleep aids and anxiety medications, and any drugs that increase sun sensitivity (photosensitizing drugs).

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure marketed for general wellness rather than one specific gradeable purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product may appeal to people interested in coriander's traditional uses, but the evidence for its effectiveness isn't established. Because it interacts with blood sugar medications, blood pressure medications, sleep aids, and drugs that increase sun sensitivity, you'll want to check your exact prescriptions before starting it.

Talk with your doctor or pharmacist to see whether Cilantrol fits your situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 21, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Cilantrol, straight from the product label.

Brand North American Herb & Spice
Barcode (UPC) 635824000112
Net contents 1 Fluid Ounce(s); 30 Milliliter(s)
Market status On market
Date entered into DSLD Jul 21, 2022
DSLD ID 269611
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Kosher
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Cilantrol by North American Herb & Spice, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
5 Drop(s)
Maximum serving Sizes:
5 Drop(s)
Servings per container
172
UPC/BARCODE
635824000112
IngredientAmount% DV
Proprietary Blend0 NP--
Coriander Seed Oil0 NP--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: Take five or more drops under the tongue in juice or water as often as needed.

Formula

Made from mountain-grown cilantro (coriander) seeds, this robust, aromatic oil is ideal for supporting digestive health. It also supports healthy detox.

Multi-spiced blend Oil of cilantro

CRC Kosher 748

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formulation

Supports a healthy detoxification response

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

CRC Kosher 748

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Cilantrol by North American Herb & Spice label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Cilantrol label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Cilantrol by North American Herb & Spice

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size5 Drop(s) Dosage formLiquid Servings per container172 Amounts shown are per serving.

Proprietary Blend

0 NP per serving Form: certified organic extra virgin Olive Oil
Interaction report

Cilantrol by North American Herb & Spice Drug Interactions

Want to check YOUR meds against Cilantrol?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
717Drugs
717 Moderate

Ingredients driving the most interactions

Coriander Seed Oil 717

Individual Drug Interactions

The ingredients in Cilantrol interact with 717 drugs. Click any drug to see the details.

1 of the 1 ingredient in Cilantrol interact with drugs. Each result below shows which ingredient is responsible. Coriander Seed Oil

Each ingredient & the kinds of drugs it affects

For each ingredient in Cilantrol with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Coriander Seed Oil4 drug types · 717 drugs

Antidiabetes Drugs

Theoretically, coriander might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Evidence from animal research suggests that coriander fruit and coriander extract can reduce blood glucose levels. Monitor blood glucose levels closely. Dose adjustments might be necessary.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, coriander might increase the risk of hypotension when taken with antihypertensive drugs.
Evidence from animal research suggests that coriander fruit can lower blood pressure.

Likelihood Possible Evidence D
Cns Depressants

Theoretically, coriander might cause additive sedative effects when taken with CNS depressants.
Evidence from animal research suggests that coriander fruit extract has sedative effects.

Likelihood Possible Evidence D
Photosensitizing Drugs

Theoretically, coriander might increase the risk of photosensitivity when taken with photosensitizing drugs.
Evidence from in vitro research suggests that coriandrin, a constituent of coriander, has photosensitizing effects.

Likelihood Possible Evidence D
Coriander Seed Oil full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Cilantrol, from the product label.

North American Herb & Spice

See all North American Herb & Spice products
Name
North American Herb & Spice
Street Address
13900 W. Polo Trail Drive
City
Lake Forest
State
IL
ZipCode
60045
Phone Number
1-800-243-5242
Web Address
www.oreganol.com
Pharmacist Counseling Corner

Cilantrol by North American Herb & Spice: Common Questions

Does Cilantrol by North American Herb & Spice interact with any medications?
Yes. Based on its ingredients, Cilantrol has a known interaction with 717 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Cilantrol contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is coriander seed oil used for?
Coriander has a long history in herbal medicine and is traditionally used for digestion, anxiety, constipation, and blood sugar support. However, the evidence to prove it works for these purposes isn't established in our data, so we can't claim it's effective for any of them.
Can I take Cilantrol with my blood pressure medication?
Coriander may lower blood pressure, so combining it with blood pressure medications could increase the risk of your pressure dropping too low. Check your specific medications with your pharmacist or doctor before starting this product.
Is coriander seed oil safe?
Coriander is generally well tolerated in normal food amounts. Concentrated medicinal doses or essential oil — as in this product — lack solid safety data, so use caution. A rare but serious allergic reaction called anaphylaxis has been reported in sensitive individuals.
Are there any side effects?
Most people tolerate coriander well when taken by mouth. The main side effect from topical use is contact dermatitis (skin irritation) in sensitive individuals. Rarely, serious allergic reactions like anaphylaxis have been reported.
Can I take this if I'm on a diabetes medication?
Coriander can lower blood glucose levels, so it may increase the risk of low blood sugar (hypoglycemia) when combined with diabetes medication. If you take a diabetes drug, talk with your doctor or pharmacist — you may need to monitor your blood sugar closely or adjust your dose.
Does Cilantrol have any fillers or inactive ingredients?
No inactive ingredients are listed for this product — it is coriander seed oil only.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Cilantrol label
Go deeper

The Full Monographs Behind Cilantrol’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Coriander

Interacts with 717 drugs

Coriander (also called cilantro) is a common cooking herb and spice that has long been used in traditional medicine for digestive complaints. As a food it is generally safe for most people,...

Read the full Coriander monograph →
Sources

Sources & How We Checked

Cilantrol's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Coriander 12 references
  1. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  2. Swanston-Flatt SK, Day C, Bailey CJ, Flatt PR. Traditional plant treatments for diabetes. Studies in normal and streptozotocin diabetic mice. Diabetologia 1990;33:462-4. PubMed
  3. Gray, A. M. and Flatt, P. R. Insulin-releasing and insulin-like activity of the traditional anti-diabetic plant Coriandrum sativum (coriander). Br.J Nutr. 1999;81(3):203-209.
  4. Kanerva, L. and Soini, M. Occupational protein contact dermatitis from coriander. Contact Dermatitis 2001;45(6):354-355. PubMed
  5. Emamghoreishi, M., Khasaki, M., and Aazam, M. F. Coriandrum sativum: evaluation of its anxiolytic effect in the elevated plus-maze. J Ethnopharmacol. 1-15-2005;96(3):365-370. PubMed
  6. Ebo, D. G., Bridts, C. H., Mertens, M. H., and Stevens, W. J. Coriander anaphylaxis in a spice grinder with undetected occupational allergy. Acta Clin Belg. 2006;61(3):152-156. PubMed
  7. Eidi, M., Eidi, A., Saeidi, A., Molanaei, S., Sadeghipour, A., Bahar, M., and Bahar, K. Effect of coriander seed (Coriandrum sativum L.) ethanol extract on insulin release from pancreatic beta cells in streptozotocin-induced diabetic rats. Phytother.Res
  8. Jabeen, Q., Bashir, S., Lyoussi, B., and Gilani, A. H. Coriander fruit exhibits gut modulatory, blood pressure lowering and diuretic activities. J Ethnopharmacol. 2-25-2009;122(1):123-130. PubMed
  9. van Toorenenbergen, A. W. and Dieges, P. H. Immunoglobulin E antibodies against coriander and other spices. J Allergy Clin Immunol. 1985;76(3):477-481. PubMed
  10. Ashwood-Smith, M. J., Warrington, P. J., Jenkins, M., Ceska, O., and Romaniuk, P. J. Photobiological properties of a novel, naturally occurring furoisocoumarin, coriandrin. Photochem.Photobiol. 1989;50(6):745-751. PubMed
  11. Sastre, J., Olmo, M., Novalvos, A., Ibanez, D., and Lahoz, C. Occupational asthma due to different spices. Allergy 1996;51(2):117-120. PubMed
  12. Beikert FC, Anastasiadou Z, Fritzen B, Frank U, Augustin M. Topical treatment of tinea pedis using 6% coriander oil in unguentum leniens: a randomized, controlled, comparative pilot study. Dermatology. 2013;226(1):47-51. PubMed

See these in context on the Coriander monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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