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Dietary supplement

Cinnamon Ingredients & Drug Interactions

by Garden Botanicals

Cinnamon label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Cinnamon against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Cinnamon is a dietary supplement by Garden Botanicals with 1 active ingredient. Its ingredients are commonly taken for blood sugar support, digestive upset, antioxidant support.Based on those ingredients, 442 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Cinnamon bark powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Cinnamon by Garden Botanicals

Ask about any prescription or over-the-counter medication and we check it for interactions with Cinnamon by Garden Botanicals — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Cinnamon by Garden Botanicals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: cinnamon bark powder derived from cassia cinnamon. The capsule also holds several inactive ingredients—hypromellose, stearic acid, vegetable magnesium stearate, silica, and talc—which serve as binders, coatings, and flow agents to hold the capsule together.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Cassia Cinnamon product and its label doesn't state a use — see Cassia Cinnamon's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for cassia cinnamon is insufficient to rate its use for amenorrhea, angina, the common cold, diabetes, diarrhea, or high cholesterol (dyslipidemia). We don't have reliable trial data showing whether this supplement actually works for any of these conditions, so we can't tell you whether to expect a benefit.

The evidence, ingredient by ingredient Cassia Cinnamon

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Cassia cinnamon is generally well tolerated in food amounts. However, at supplement doses—especially high or long-term ones—coumarin in cassia cinnamon may harm your liver over time.

Very high doses (50–7,000 mg daily) have caused liver damage in people, though it reversed after stopping. In clinical trials, doses of 360 mg to 12 grams daily for three months did not significantly raise liver enzymes, but the safety concern remains for prolonged use.

Rare side effects reported include a rash in one trial participant and a low blood sugar (hypoglycemic) seizure in another, though causation is unclear. One person with a cinnamon allergy developed eyelid dermatitis from dietary cinnamon, which cleared five days after discontinuing it.

During pregnancy and breastfeeding, food amounts of cinnamon are likely fine, but avoid medicinal or high-dose supplement amounts; safety data in these settings is limited.

Side effects, ingredient by ingredient Cassia Cinnamon

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Cassia Cinnamon.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 443 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your exact medications before starting if you take drugs that affect the liver (hepatotoxic drugs) or diabetes medications (antidiabetes drugs). Both can have Moderate-severity interactions with cassia cinnamon.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you eat cinnamon in food, this supplement dose is probably safe. But if you take medications for diabetes or liver disease, or any prescription drug, talk to your pharmacist before starting.

The coumarin in cassia cinnamon is the main worry with long-term use. We don't have proof this supplement actually works for any health condition.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 25, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Cinnamon, straight from the product label.

Brand Garden Botanicals
Barcode (UPC) 035046091996
Net contents 60 Vegicap(s)
Market status On market
Date entered into DSLD Jun 25, 2015
DSLD ID 46449
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Cinnamon by Garden Botanicals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Vegicap(s)
Maximum serving Sizes:
2 Vegicap(s)
UPC/BARCODE
035046091996
IngredientAmount% DV
Cinnamon bark powder500 mg--

Other ingredients: Hypromellose, Stearic Acid, Vegetable Magnesium Stearate, Silica, Talc

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Cinnulin PF(R) High Potency Cinnamon Extract is the only patented cinnamon extract to be USDA-verified.

(C) 2015 Copyright Windmill(R) Health Products All rights reserved.

Cinnulin PF(R) is a registered trademark of Integrity Nutracueticals.

Seals/Symbols

100% VEGAN

General Statements

MADE IN THE U.S.A.

Made in the USA.

(Standardized Extract 500 mg)

Helps Support Normal Blood Sugar Helps Support Metabolism Helps Support Digestion

General

ITEM# N9199

Precautions

~ Keep out of reach of children.

~ Do not use if inner seal is broken.

Storage

~ Store in a cool, dry place. ~ Protect from heat, light and moisture.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formula

Cinnulin PF(R) Water Soluble Extract

FDA Statement of Identity

DIETARY SUPPLEMENT

Suggested/Recommended/Usage/Directions

DIRECTIONS: TAKE 1 OR 2 CAPSULES DAILY AS A DIETARY SUPPLEMENT.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Cinnamon by Garden Botanicals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Cinnamon label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Cinnamon by Garden Botanicals

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Vegicap(s) Dosage formCapsule Amounts shown are per serving.

Cinnamon bark powder

Interacts with
442 drugs
500 mg per serving Form: Cinnulin PF

Cassia cinnamon is the common, inexpensive cinnamon used in cooking, and it is also taken as a supplement, most often for blood sugar support. The evi...

Cinnamon bark powder monograph & interactions

Other (inactive) ingredients: Hypromellose, Stearic Acid, Vegetable Magnesium Stearate, Silica, Talc. These complete the product’s ingredient list but are not active constituents.

Interaction report

Cinnamon by Garden Botanicals Drug Interactions

Want to check YOUR meds against Cinnamon?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
442Drugs
442 Moderate

Ingredients driving the most interactions

Cinnamon bark powder 442

Individual Drug Interactions

The ingredients in Cinnamon interact with 442 drugs. Click any drug to see the details.

1 of the 1 ingredient in Cinnamon interact with drugs. Each result below shows which ingredient is responsible. Cinnamon bark powder

Each ingredient & the kinds of drugs it affects

For each ingredient in Cinnamon with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Cinnamon bark powder2 drug types · 442 drugs

Antidiabetes Drugs

Theoretically, cassia cinnamon may have additive effects with antidiabetes drugs.
Cassia cinnamon may lower blood glucose levels, and have additive effects in patients treated with antidiabetic agents. Dose adjustments to diabetes medications might be necessary.

Likelihood Possible Evidence B
Hepatotoxic Drugs

Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
There is some concern that ingesting large amounts of cassia cinnamon for an extended duration might cause hepatotoxicity in some people. Cassia cinnamon contains coumarin, which can cause hepatotoxicity in animal models. In humans, very high doses of coumarin from 50-7000 mg/day can result in hepatotoxicity that resolves when coumarin use is discontinued. Lower amounts might also cause liver problems in sensitive people, such as those with liver disease or those taking potentially hepatotoxic agents.

Likelihood Possible Evidence D
Cinnamon bark powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Cinnamon, from the product label.

Garden Botanicals

See all Garden Botanicals products
Name
Windmill Health Products
Street Address
6 Henderson Dr.
City
West Caldwell
State
NJ
ZipCode
07006
Pharmacist Counseling Corner

Cinnamon by Garden Botanicals: Common Questions

Does Cinnamon by Garden Botanicals interact with any medications?
Yes. Based on its ingredients, Cinnamon has a known interaction with 442 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Cinnamon contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does cinnamon really help with diabetes?
The evidence isn't established in our data. We have insufficient reliable evidence to say whether cinnamon works for blood sugar control. If you have diabetes and are thinking about adding a supplement, talk to your doctor first.
Is cassia cinnamon the same as regular cinnamon?
This product is cassia cinnamon, which comes from a different plant than Ceylon cinnamon (the "true" cinnamon). Cassia is the more common type in the U.S., but it contains higher levels of coumarin, the compound that raises the liver safety concern.
Can I take this while pregnant?
Food amounts of cinnamon are likely safe, but avoid medicinal or high-dose supplement amounts during pregnancy because we don't have enough safety data to know whether it's okay.
What was that rash I read about in the adverse effects?
One person in a clinical trial developed a rash while taking 1 gram of cinnamon daily for 90 days. It's a rare event, and we don't know for certain the cinnamon caused it. Another person with a known cinnamon allergy developed an eyelid rash from eating cinnamon, which cleared within five days of stopping it.
How much cinnamon is too much?
The data we have shows that doses of 360 mg to 12 grams daily for three months did not significantly raise liver enzymes in clinical trials. However, very high doses of coumarin (50–7,000 mg daily from other sources) have caused liver damage in people, so prolonged high-dose use is a concern. Stick to normal supplement doses and talk to your pharmacist if you're taking this long-term.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Cinnamon label
Go deeper

The Full Monographs Behind Cinnamon’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Cassia Cinnamon

Interacts with 442 drugs

Cassia cinnamon is the common, inexpensive cinnamon used in cooking, and it is also taken as a supplement, most often for blood sugar support. The evidence for its health benefits is mixed a...

Read the full Cassia Cinnamon monograph →
Sources

Sources & How We Checked

Cinnamon's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 20 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Cassia Cinnamon 20 references
  1. Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
  2. Khan A, Safdar M, Ali Khan M, et al. Cinnamon improves glucose and lipids of people with type 2 diabetes. Diabetes Care 2003;26:3215-8. PubMed
  3. De Benito V, Alzaga R. Occupational allergic contact dermatitis from cassia (Chinese cinnamon) as a flavouring agent in coffee. Contact Dermatitis 1999;40:165. PubMed
  4. Drake TE, Maibach HI. Allergic contact dermatitis and stomatitis caused by a cinnamic aldehyde-flavored toothpaste. Arch Dermatol 1976;112:202-3.
  5. Press release. Cinnamon capsules to reduce blood sugar are medicinal products! Efficacy has not been scientifically proven - some products contain high levels of coumarin. Federal Institute of Risk Assessment (BfM), Germany, November 11, 2006. Available a
  6. Felter SP, Vassallo JD, Carlton BD, Daston GP. A safety assessment of coumarin taking into account species-specificity of toxicokinetics. Food Chem Toxicol 2006;44:462-75. PubMed
  7. Crawford P. Effectiveness of cinnamon for lowering hemoglobin A1C in patients with type 2 diabetes: a randomized, controlled trial. J Am Board Fam Med 2009;22:507-12. PubMed
  8. Akilen, R., Tsiami, A., Devendra, D., and Robinson, N. Glycated haemoglobin and blood pressure-lowering effect of cinnamon in multi-ethnic Type 2 diabetic patients in the UK: a randomized, placebo-controlled, double-blind clinical trial. Diabet.Med. 2010; PubMed
  9. Lu T, Sheng H Wu J Cheng Y Zhu J Chen Y. Cinnamon extract improves fasting blood glucose and glycosylated hemoglobin level in Chinese patients with type 2 diabetes. Nutr Res. 2012;32(6):408-412. PubMed
  10. Choi, J., Lee, K. T., Ka, H., Jung, W. T., Jung, H. J., and Park, H. J. Constituents of the essential oil of the Cinnamomum cassia stem bark and the biological properties. Arch Pharm Res 2001;24(5):418-423.
  11. Altschuler JA, Casella SJ, MacKenzie TA, Curtis KM. The effect of cinnamon on A1C among adolescents with type 1 diabetes. Diabetes Care 2007;30(4):813-6. PubMed
  12. Stoecker BR, Zhan Z, Luo R, et al. Cinnamon extract lowers blood glucose in hyperglycemic subjects. FASEB J. 2010;22:722.1 (Abstract only). DOI
  13. Admani S, Hill H, Jacob SE. Cinnamon Sugar Scrub Dermatitis: "Natural" Is Not Always Best. Pediatr Dermatol. 2017;34(1):e42-e43. PubMed
  14. Isaac-Renton M, Li MK, Parsons LM. Cinnamon spice and everything not nice: many features of intraoral allergy to cinnamic aldehyde. Dermatitis. 2015;26(3):116-21. PubMed
  15. Vandersall A, Katta R. Eyelid dermatitis as a manifestation of systemic contact dermatitis to cinnamon. Dermatitis. 2015 Jul-Aug;26(4):189. PubMed
  16. Wickenberg J, Lindstedt S, Nilsson J, Hlebowicz J. Cassia cinnamon does not change the insulin sensitivity or the liver enzymes in subjects with impaired glucose tolerance. Nutr J 2014 Sep 24;13:96. PubMed
  17. Brancheau D, Patel B, Zughaib M. Do cinnamon supplements cause acute hepatitis? Am J Case Rep 2015;16:250-4. PubMed
  18. Shekarchizadeh-Esfahani P, Heydarpour F, Izadi F, Jalili C. The effect of cinnamon supplementation on liver enzymes in adults: A systematic review and meta-analysis of randomized controlled trials. Complement Ther Med 2021;58:102699. PubMed
  19. Bernaola J, Valverde-Monge M, Otal-Buesa M, Cullen D, Heras-Mendaza F. Cinnamon allergic contact cheilitis. Contact Dermatitis 2023;88(5):418-419. PubMed
  20. Patel K, Howard M, Tate B. Cheilitis caused by allergic contact dermatitis to cinnamon in chai tea: A case report. Contact Dermatitis 2023;88(3):239-240. PubMed

See these in context on the Cassia Cinnamon monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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