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Dietary supplement

Cinnamon Ingredients & Drug Interactions

by Herb Pharm

Liquid Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Cinnamon is a dietary supplement by Herb Pharm with 1 active ingredient. Its ingredients are commonly taken for blood sugar support, digestive upset, antioxidant support.Based on those ingredients, 442 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Cinnamon Bark Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Cinnamon by Herb Pharm

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This is a straightforward single-ingredient product: cinnamon bark extract — the active ingredient. It's a liquid made with cane alcohol, distilled water, and glycerin, which help deliver the extract.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Cassia Cinnamon's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Gastrointestinal system restoration.
  • We looked for evidence on: Diarrhea, Gastritis, Nausea and vomiting, Digestive health, Stomach comfort.
  • The closest evidence on file: Cassia Cinnamon is rated "Insufficient Reliable Evidence To Rate" for Diarrhea (Natural Medicines).
  • Also on file: Cassia Cinnamon is rated "Insufficient Reliable Evidence To Rate" for Nausea and vomiting, Gastritis.

The evidence we hold on cinnamon doesn't establish whether it works for amenorrhea, angina, common cold, diabetes, diarrhea, or dyslipidemia (high cholesterol). The data shows insufficient reliable evidence to rate it for any of those uses.

If you're considering cinnamon for one of these, chat with your pharmacist or doctor about whether the clinical evidence supports trying it.

The evidence, ingredient by ingredient Cassia Cinnamon

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Cinnamon is generally well tolerated in food amounts. At supplement doses — especially high ones taken long-term — there's a caution about coumarin, which the liver metabolizes and, in very large amounts, can harm over time.

In clinical trials, doses of 360 mg to 12 grams daily for 3 months didn't significantly raise liver enzymes, but the safety data advises against medicinal or high-dose supplement amounts during pregnancy. Breastfeeding safety data isn't on file.

A very small number of trial participants reported a rash or, in one case, a hypoglycemic seizure, though the seizure was reported just a day after starting and may not have been caused by the product.

Side effects, ingredient by ingredient Cassia Cinnamon

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Cassia Cinnamon.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 443 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start, double-check any medications that harm the liver (hepatotoxic drugs) and any diabetes or blood sugar medications. Cinnamon may add to liver stress with long-term high doses and may lower blood glucose, potentially requiring dose changes.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Cinnamon liquid extract may be worth considering if you're looking for a culinary herb in supplement form, but evidence for specific health uses isn't established in our data. If you take diabetes medications or drugs that stress the liver, check your exact prescriptions with the interaction tool first — dose adjustments might be needed.

Pregnant or breastfeeding? Stick to food amounts and talk to your pharmacist.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 22, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Cinnamon, straight from the product label.

Brand Herb Pharm
Barcode (UPC) 090700000394
Net contents 1 Fluid Ounce(s); 30 mL
Market status On market
Date entered into DSLD Aug 22, 2025
DSLD ID 336564
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Organic, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Cinnamon by Herb Pharm, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.7 mL
Maximum serving Sizes:
0.7 mL
Servings per container
42
UPC/BARCODE
090700000394
IngredientAmount% DV
Cinnamon Bark Extract634 mg--

Other ingredients: Cane Alcohol, Water, Distilled, Glycerin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use Shake well before using Adults: Add 1 squeeze of the dropper bulb to 4 oz. of water or juice, 2 or 3 times per day. Best taken between meals.

Precautions

Caution: Seek expert medical advice before taking during pregnancy.

Keep out of the reach of children

Storage

Store away from heat & light

Formula

Cinnamomum cassia

Cinnamon liquid extract

Formulation

System restoration Gastrointestinal

USDA Organic

Gluten-free

Certified organic by Organic Certifiers

Seals/Symbols

USDA Organic

FDA Statement of Identity

Herbal Supplement

FDA Disclaimer Statement

This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

See for yourself

Cinnamon by Herb Pharm label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Cinnamon by Herb Pharm

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.7 mL Dosage formLiquid Servings per container42 Amounts shown are per serving.

Cinnamon Bark Extract

Interacts with
442 drugs
634 mg per serving Form: Cinnamomum aromaticum Bark Extract

Cassia cinnamon is the common, inexpensive cinnamon used in cooking, and it is also taken as a supplement, most often for blood sugar support. The evi...

Cinnamon Bark Extract monograph & interactions

Other (inactive) ingredients: Cane Alcohol, Water, Distilled, Glycerin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Cinnamon by Herb Pharm Drug Interactions

Want to check YOUR meds against Cinnamon?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
442Drugs
442 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Cinnamon with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Cinnamon Bark Extract2 drug types · 442 drugs

Antidiabetes Drugs

Theoretically, cassia cinnamon may have additive effects with antidiabetes drugs.
Cassia cinnamon may lower blood glucose levels, and have additive effects in patients treated with antidiabetic agents. Dose adjustments to diabetes medications might be necessary.

Likelihood Possible Evidence B
Hepatotoxic Drugs

Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
There is some concern that ingesting large amounts of cassia cinnamon for an extended duration might cause hepatotoxicity in some people. Cassia cinnamon contains coumarin, which can cause hepatotoxicity in animal models. In humans, very high doses of coumarin from 50-7000 mg/day can result in hepatotoxicity that resolves when coumarin use is discontinued. Lower amounts might also cause liver problems in sensitive people, such as those with liver disease or those taking potentially hepatotoxic agents.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Cinnamon, from the product label.

Herb Pharm

See all Herb Pharm products
Name
Herb Pharm
City
Williams
State
OR
ZipCode
97544
Phone Number
800-348-4372
Web Address
www.herb-pharm.com
Pharmacist Counseling Corner

Cinnamon by Herb Pharm: Common Questions

Does Cinnamon by Herb Pharm interact with any medications?
Yes. Based on its ingredients, Cinnamon has a known interaction with 442 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Cinnamon contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this cinnamon safe to take long-term?
At food amounts, yes — generally well tolerated. At supplement doses, especially high ones, the coumarin it contains can stress the liver over extended time. If you're thinking long-term supplementing, talk to your pharmacist about what dose makes sense for you.
Can I take this if I'm pregnant or nursing?
Food amounts are likely fine. The data advises against medicinal or high-dose supplement amounts during pregnancy. For breastfeeding, we don't have safety data on file, so check with your pharmacist or doctor for personalized advice.
Does this actually help with diabetes or high cholesterol?
The evidence we hold doesn't establish that it works for either. The data shows insufficient reliable evidence to rate cinnamon for diabetes, cholesterol, or the other conditions listed. That doesn't mean it never helps — just that the science isn't settled in our data.
What's in the liquid besides cinnamon?
Cane alcohol, distilled water, and glycerin — those are the inactive ingredients that carry the extract.
Will this lower my blood sugar if I'm on diabetes medication?
Possibly. Cinnamon may lower blood glucose, which means your diabetes drugs could have additive effects and might need dose adjusting. Don't change anything on your own — run this by your pharmacist or doctor first.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Cinnamon is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Cinnamon label
Sources

Sources & How We Checked

Cinnamon's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 20 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Cassia Cinnamon 20 references
  1. Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
  2. Khan A, Safdar M, Ali Khan M, et al. Cinnamon improves glucose and lipids of people with type 2 diabetes. Diabetes Care 2003;26:3215-8. PubMed
  3. De Benito V, Alzaga R. Occupational allergic contact dermatitis from cassia (Chinese cinnamon) as a flavouring agent in coffee. Contact Dermatitis 1999;40:165. PubMed
  4. Drake TE, Maibach HI. Allergic contact dermatitis and stomatitis caused by a cinnamic aldehyde-flavored toothpaste. Arch Dermatol 1976;112:202-3.
  5. Press release. Cinnamon capsules to reduce blood sugar are medicinal products! Efficacy has not been scientifically proven - some products contain high levels of coumarin. Federal Institute of Risk Assessment (BfM), Germany, November 11, 2006. Available a
  6. Felter SP, Vassallo JD, Carlton BD, Daston GP. A safety assessment of coumarin taking into account species-specificity of toxicokinetics. Food Chem Toxicol 2006;44:462-75. PubMed
  7. Crawford P. Effectiveness of cinnamon for lowering hemoglobin A1C in patients with type 2 diabetes: a randomized, controlled trial. J Am Board Fam Med 2009;22:507-12. PubMed
  8. Akilen, R., Tsiami, A., Devendra, D., and Robinson, N. Glycated haemoglobin and blood pressure-lowering effect of cinnamon in multi-ethnic Type 2 diabetic patients in the UK: a randomized, placebo-controlled, double-blind clinical trial. Diabet.Med. 2010; PubMed
  9. Lu T, Sheng H Wu J Cheng Y Zhu J Chen Y. Cinnamon extract improves fasting blood glucose and glycosylated hemoglobin level in Chinese patients with type 2 diabetes. Nutr Res. 2012;32(6):408-412. PubMed
  10. Choi, J., Lee, K. T., Ka, H., Jung, W. T., Jung, H. J., and Park, H. J. Constituents of the essential oil of the Cinnamomum cassia stem bark and the biological properties. Arch Pharm Res 2001;24(5):418-423.
  11. Altschuler JA, Casella SJ, MacKenzie TA, Curtis KM. The effect of cinnamon on A1C among adolescents with type 1 diabetes. Diabetes Care 2007;30(4):813-6. PubMed
  12. Stoecker BR, Zhan Z, Luo R, et al. Cinnamon extract lowers blood glucose in hyperglycemic subjects. FASEB J. 2010;22:722.1 (Abstract only). DOI
  13. Admani S, Hill H, Jacob SE. Cinnamon Sugar Scrub Dermatitis: "Natural" Is Not Always Best. Pediatr Dermatol. 2017;34(1):e42-e43. PubMed
  14. Isaac-Renton M, Li MK, Parsons LM. Cinnamon spice and everything not nice: many features of intraoral allergy to cinnamic aldehyde. Dermatitis. 2015;26(3):116-21. PubMed
  15. Vandersall A, Katta R. Eyelid dermatitis as a manifestation of systemic contact dermatitis to cinnamon. Dermatitis. 2015 Jul-Aug;26(4):189. PubMed
  16. Wickenberg J, Lindstedt S, Nilsson J, Hlebowicz J. Cassia cinnamon does not change the insulin sensitivity or the liver enzymes in subjects with impaired glucose tolerance. Nutr J 2014 Sep 24;13:96. PubMed
  17. Brancheau D, Patel B, Zughaib M. Do cinnamon supplements cause acute hepatitis? Am J Case Rep 2015;16:250-4. PubMed
  18. Shekarchizadeh-Esfahani P, Heydarpour F, Izadi F, Jalili C. The effect of cinnamon supplementation on liver enzymes in adults: A systematic review and meta-analysis of randomized controlled trials. Complement Ther Med 2021;58:102699. PubMed
  19. Bernaola J, Valverde-Monge M, Otal-Buesa M, Cullen D, Heras-Mendaza F. Cinnamon allergic contact cheilitis. Contact Dermatitis 2023;88(5):418-419. PubMed
  20. Patel K, Howard M, Tate B. Cheilitis caused by allergic contact dermatitis to cinnamon in chai tea: A case report. Contact Dermatitis 2023;88(3):239-240. PubMed

See these in context on the Cassia Cinnamon monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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