Interactions on record — worth a quick check against your medications. Based on 3 of 4 ingredients. Check your meds →
Dietary supplement

Fiber-Immune Support Apple-Cinnamon Flavor Ingredients & Drug Interactions

by Life Extension

Fiber-Immune Support Apple-Cinnamon Flavor label
See full label image
Powder Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Fiber-Immune Support Apple-Cinnamon Flavor against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Fiber-Immune Support Apple-Cinnamon Flavor is a dietary supplement by Life Extension with 4 active ingredients. Its ingredients are commonly taken for constipation, diarrhea, high cholesterol.Based on those ingredients, 2,102 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Dietary Fiber, Wellmune. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Fiber-Immune Support Apple-Cinnamon Flavor by Life Extension

Ask about any prescription or over-the-counter medication and we check it for interactions with Fiber-Immune Support Apple-Cinnamon Flavor by Life Extension — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Fiber-Immune Support Apple-Cinnamon Flavor by Life Extension

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 30, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 4 active ingredients.
  • “Proprietary Fiber Blend” is a proprietary blend — the label gives one combined amount (7.30 Gram(s)) without saying how much of each component you get.

This powder has 5 active ingredients: soluble fiber, insoluble fiber, psyllium husk powder, a proprietary fiber blend, organic baobab fruit powder, and Wellmune (a branded form of beta-glucans). The fibers work together to support digestive health, while baobab and beta-glucans are included for immune and overall wellness support.

The product also contains inactive ingredients — maltodextrin, rice starch, natural apple flavor, stevia extract, cinnamon powder, and modified food starch — that help with texture, taste, and shelf life.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: fiber and immune support.
  • We looked for evidence on: Constipation, Diarrhea, Dyslipidemia, Coronary heart disease (CHD), Exercise-induced respiratory infections, Lower respiratory tract infections — and 4 related terms.
  • The strongest evidence on file: Black Psyllium is rated "Effective" for Constipation (Natural Medicines).
  • Also on file: Black Psyllium is rated "Likely Effective" for Coronary heart disease (CHD).
  • Also on file: Beta-glucans is rated "Likely Effective" for Coronary heart disease (CHD), Dyslipidemia.

Beta-glucans (Wellmune) in this product are likely effective for helping manage cholesterol levels (dyslipidemia) and supporting heart health (coronary heart disease). For baobab fruit, the evidence isn't established in the data we hold — insufficient reliable evidence exists to rate it for iron-deficiency anemia, eczema, diabetes, or rheumatoid arthritis.

We have no effectiveness data for the other fiber ingredients in the sources we checked.

The evidence, ingredient by ingredient Black Psyllium Baobab Beta-glucans

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Beta-glucans from food sources are generally well tolerated by most people. In concentrated supplement form, however, safety data is limited — the product itself notes caution should be used.

One clinical trial of children and young adults reported one patient developed temporary liver enzyme elevations after starting high-dose oral beta-glucans. Topically applied beta-glucans cream caused mild, self-limiting skin reactions in a small number of trial participants.

Baobab fruit powder is generally considered safe as a food, but high-dose supplement use isn't well studied. One case report documented a severe allergic reaction (anaphylaxis) to baobab fruit in a person who consumed a snack bar containing baobab and other ingredients — they experienced throat tightness, swelling, and gastrointestinal symptoms.

If you have a known fruit allergy, mention this product to your doctor before taking it. Pregnancy and breastfeeding safety data for both baobab and beta-glucans supplements is limited — talk with your doctor or pharmacist about whether this product is right for you during these periods.

Side effects, ingredient by ingredient Black Psyllium Baobab Beta-glucans

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 3 matched ingredients can interact with medications — Black Psyllium, Beta-glucans.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs; heart-rhythm medications; lithium.
  • For scale: 2,103 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, double-check it with your doctor or pharmacist if you're on antihypertensive drugs (blood pressure medications) or immunosuppressants. Beta-glucans in this powder could lower blood pressure further or interfere with immune-suppressing therapy.

No other interactions are documented for the fiber and baobab ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This fiber and immune support product may work well if you're looking to manage cholesterol and support heart health through beta-glucans. Anyone taking blood pressure medications or drugs that suppress the immune system should check with their doctor or pharmacist first — the beta-glucans here could interfere with how those drugs work.

If you have a history of fruit allergies or are pregnant or breastfeeding, discuss this product with your own healthcare provider before starting it.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 24, 2016.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Fiber-Immune Support Apple-Cinnamon Flavor, straight from the product label.

Brand Life Extension
Barcode (UPC) 737870200710
Net contents 235 Gram(s); 0.52 lb; 8.29 oz.
Market status On market
Date entered into DSLD Aug 24, 2016
DSLD ID 63293
Product type Other Combinations
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Fiber-Immune Support Apple-Cinnamon Flavor by Life Extension, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
7.8 Gram(s)
Maximum serving Sizes:
7.8 Gram(s)
Servings per container
30
UPC/BARCODE
737870200710
IngredientAmount% DV
Calories30 Calorie(s)--
Total Carbohydrates6.5 Gram(s)2%
Dietary Fiber6 Gram(s)24%
Soluble Fiber4.9 Gram(s)--
Insoluble Fiber1.1 Gram(s)--
Psyllium husk powder0 NP--
Proprietary Fiber Blend7.3 Gram(s)--
organic Baobob (Adansonia digitata ) fruit powder0 NP--
Wellmune0 NP--

Other ingredients: Maltodextrin, Rice Starch, natural Apple flavor, Stevia extract, Cinnamon powder, modified Food Starch

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

This supplement should be taken in conjunction with a healthy diet and regular exercise. Results may vary.

Read the entire label and follow the directions carefully prior to use. DIRECTIONS: Take one (1) scoop with at least 8 to 10 ounces (a full glass) of water or other fluid once or twice daily, or as recommended by a healthcare practitioner. Stir vigorously and drink immediately. Take at least two hours apart from medications. Taking this product without enough liquid may cause choking. See choking warning.

General Statements

Diets low in saturated fat and cholesterol and rich in fruits, vegetables, and grain products that contain some types of dietary fiber, particularly soluble fiber, may reduce the risk of heart disease, a disease associated with many factors.

Scan for product info

Supports Healthy Immune Response and Optimal GI Function

To report a serious adverse event or obtain product information, contact 1-866-280-2852.

Precautions

WARNINGS: ~ KEEP OUT OF REACH OF CHILDREN.

~ DO NOT EXCEED RECOMMENDED DOSE. ~ Do not purchase if outer seal is broken or damaged.

~ When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

Take at least two hours apart from medications.

Taking this product without enough liquid may cause choking. See choking warning. Choking: Taking this product without adequate fluid may cause it to swell and block your throat or esophagus and may cause choking. Do not take this product if you have difficulty in swallowing. If you experience chest pains, vomiting, or difficulty in swallowing or breathing after taking this product, seek immediate medical attention.

Brand IP Statement(s)

Wellmune is a registered trademark of Biothera.

Storage

Store tightly closed in a cool, dry place.

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formulation

Non-GMO

The highly purified yeast extract has mannan and manno-proteins removed, as these can trigger an allergic and inflammatory bowel flare in individuals with yeast allergies, IBD, or Crohn’s Disease.

General

QE02007B

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Fiber-Immune Support Apple-Cinnamon Flavor by Life Extension label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Fiber-Immune Support Apple-Cinnamon Flavor label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Fiber-Immune Support Apple-Cinnamon Flavor by Life Extension

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size7.8 Gram(s) Dosage formPowder Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Dietary Fiber

Interacts with
2,025 drugs
6 Gram(s) per serving

Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. I...

Dietary Fiber monograph & interactions
  • › Soluble Fiber
  • › Insoluble Fiber

Proprietary Fiber Blend

7.3 Gram(s) per serving

Other (inactive) ingredients: Maltodextrin, Rice Starch, Natural Apple flavor, Stevia extract, Cinnamon powder, Modified Food Starch. These complete the product’s ingredient list but are not active constituents.

Interaction report

Fiber-Immune Support Apple-Cinnamon Flavor by Life Extension Drug Interactions

Want to check YOUR meds against Fiber-Immune Support Apple-Cinnamon Flavor?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2,102Drugs
316 Moderate 1,786 Minor

Ingredients driving the most interactions

Dietary Fiber 2,025
Wellmune 293

Individual Drug Interactions

The ingredients in Fiber-Immune Support Apple-Cinnamon Flavor interact with 2,102 drugs. Click any drug to see the details.

2 of the 4 ingredients in Fiber-Immune Support Apple-Cinnamon Flavor interact with drugs. Each result below shows which ingredient is responsible. Dietary Fiber Wellmune

Each ingredient & the kinds of drugs it affects

For each ingredient in Fiber-Immune Support Apple-Cinnamon Flavor with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Dietary Fiber7 drug types · 2,025 drugs

Carbamazepine (Tegretol)

Theoretically, black psyllium might reduce the effects of carbamazepine and increase the risk for convulsions.
Theoretically, black psyllium might reduce carbamazepine absorption. A preliminary study using blond psyllium reported decreased carbamazepine bioavailability due to binding of the drug to psyllium, as well as reduction of available fluid in the gut for dissolution of the drug. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D
Lithium

Theoretically, taking black psyllium at the same time as lithium might reduce lithium absorption.
The fiber in black psyllium might reduce lithium absorption and plasma levels. Some case reports describe a reduction in plasma lithium levels with concomitant administration of blond psyllium. This was reversed when psyllium was stopped. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D
Metformin (Glucophage)

Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Animal research shows that concurrent consumption of blond psyllium with metformin slows and increases the absorption of metformin. This interaction may also occur with black psyllium. To avoid changes in absorption, take psyllium 30-60 minutes after metformin.

Likelihood Possible Evidence D
Olanzapine (Zyprexa)

Theoretically, taking black psyllium at the same time as olanzapine might reduce olanzapine absorption.
The fiber in black psyllium might decrease the absorption of olanzapine. A single case report describes a reduction in the effectiveness of olanzapine when it was concomitantly administered with an unspecified type of psyllium 3 grams orally twice daily. This effect was reversed when psyllium was stopped.

Likelihood Possible Evidence D
Digoxin (Lanoxin)

Theoretically, taking black psyllium at the same time as digoxin might reduce digoxin absorption and decrease digoxin levels.
Psyllium might bind digoxin in the gut. However, some clinical evidence suggests that psyllium does not impact digoxin absorption.

Likelihood Unlikely Evidence B
Ethinyl Estradiol

Theoretically, taking black psyllium at the same time as ethinyl estradiol might alter levels of estradiol.
Concurrent use of blond psyllium with ethinyl estradiol results in a slight increase in the extent of ethinyl estradiol absorption and a slower rate of absorption. This is unlikely to be clinically significant.

Likelihood Unlikely Evidence D
Oral Drugs

Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Psyllium seems to have variable effects on drug absorption. To avoid changes in absorption, take psyllium 30-60 minutes after oral medications. Animal research shows that blond psyllium delays and increases the absorption of metformin and ethinyl estradiol. Case reports and animal research suggest that blond psyllium might reduce absorption of lithium, digoxin, olanzapine, and carbamazepine. Finally, some pharmacokinetic studies show that psyllium does not affect the absorption of levothyroxine or warfarin. Although many of these studies evaluated blond psyllium, the fiber content in black psyllium may have similar effects.

Likelihood Possible Evidence B
Dietary Fiber full monograph & interactions

Wellmune2 drug types · 293 drugs

Antihypertensive Drugs

Theoretically, taking beta-glucans with antihypertensive drugs might increase the risk of hypotension.
Clinical research shows that taking beta-glucans may reduce systolic and diastolic blood pressure in some hypertensive individuals.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, beta-glucans might interfere with immunosuppressive therapy.
Some clinical research shows that beta-glucans have immunostimulant effects.

Likelihood Possible Evidence D
Wellmune full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Fiber-Immune Support Apple-Cinnamon Flavor, from the product label.

Life Extension

See all Life Extension products
Name
Quality Supplements and Vitamins, Inc.
City
Ft. Lauderdale
State
FL
ZipCode
33309
Phone Number
1-866-280-2852
Web Address
LifeExtension.com
Pharmacist Counseling Corner

Fiber-Immune Support Apple-Cinnamon Flavor by Life Extension: Common Questions

Does Fiber-Immune Support Apple-Cinnamon Flavor by Life Extension interact with any medications?
Yes. Based on its ingredients, Fiber-Immune Support Apple-Cinnamon Flavor has a known interaction with 2,102 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Fiber-Immune Support Apple-Cinnamon Flavor contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does baobab fruit in this powder have any documented interactions with medications?
No interactions are documented in our data for baobab fruit powder. However, always check your full medication list with your doctor or pharmacist before starting any new supplement.
Is this product safe to use if I'm taking medications for my heart or blood pressure?
If you're on blood pressure medication, the beta-glucans here could lower your pressure further and raise the risk of dizziness or lightheadedness. Talk with your doctor or pharmacist before adding this product — they'll know your specific situation and can advise whether it's safe for you.
What's Wellmune and what does it do?
Wellmune is a branded form of beta-glucans, compounds that may help manage cholesterol and support heart health. It's included in this product to boost its immune-support role.
Can I take this during pregnancy or breastfeeding?
Safety data for both the beta-glucans and baobab in this product during pregnancy and breastfeeding is limited — there isn't enough information to know either way. Talk with your doctor or pharmacist for personalized advice.
I have a fruit allergy — is baobab safe for me?
One person had a severe allergic reaction (anaphylaxis) to baobab fruit. If you have any history of fruit allergies, especially to African or tropical fruits, mention this product to your doctor or pharmacist before using it.
Does this product contain any fillers?
Yes, it contains inactive ingredients: maltodextrin, rice starch, natural apple flavor, stevia extract, cinnamon powder, and modified food starch. These help with texture, taste, and shelf life.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Fiber-Immune Support Apple-Cinnamon Flavor is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Fiber-Immune Support Apple-Cinnamon Flavor label
Go deeper

The Full Monographs Behind Fiber-Immune Support Apple-Cinnamon Flavor’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Black Psyllium

Interacts with 2,025 drugs

Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. It is best known and most studied for rel...

Read the full Black Psyllium monograph → Herb & supplement monograph

Baobab

Baobab is a nutrient-rich fruit from a tree native to Africa and is most often used as a food and source of vitamin C and fiber. Early research hints it may help with blood sugar and digesti...

Read the full Baobab monograph → Herb & supplement monograph

Beta-glucans

Interacts with 293 drugs

Beta-glucans are natural fibers found in oats, barley, mushrooms, and yeast. The strongest evidence supports the oat and barley types for modestly lowering cholesterol and blood sugar, while...

Read the full Beta-glucans monograph →
Sources

Sources & How We Checked

Fiber-Immune Support Apple-Cinnamon Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 30 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Black Psyllium 18 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  3. Covington TR, et al. Handbook of Nonprescription Drugs. 11th ed. Washington, DC: American Pharmaceutical Association, 1996.
  4. Etman M. Effect of a bulk forming laxative on the bioavailablility of carbamazepine in man. Drug Dev Ind Pharm 1995;21:1901-6.
  5. Perlman BB. Interaction between lithium salts and ispaghula husk. Lancet 1990;335:416.
  6. Vaswani SK, Hamilton RG, Valentine MD, Adkinson NF. Psyllium laxative-induced anaphylaxis, asthma, and rhinitis. Allergy 1996;51:266-8. PubMed
  7. Lantner RR, Espiritu BR, Zumerchik P, Tobin MC. Anaphylaxis following ingestion of a psyllium-containing cereal. JAMA 1990;264:2534-6. DOI
  8. Kaplan MJ. Anaphylactic reaction to "Heartwise." N Engl J Med 1990;323:1072-3. DOI
  9. Nordstrom M, Melander A, Robertsson E, Steen B. Influence of wheat bran and of a bulk-forming ispaghula cathartic on the bioavailability of digoxin in geriatric in-patients. Drug Nutr Interact 1987;5:67-9..
  10. Robinson DS, Benjamin DM, McCormack JJ. Interaction of warfarin and nonsystemic gastrointestinal drugs. Clin Pharmacol Ther 1971;12:491-5. PubMed
  11. Garcia JJ, Fernandez N, Diez MJ, et al. Influence of two dietary fibers in the oral bioavailability and other pharmacokinetic parameters of ethinyloestradiol. Contraception 2000;62:253-7. PubMed
  12. Fernandez N, Lopez C, Díez R, et al. Drug interactions with the dietary fiber Plantago ovata husk. Expert Opin Drug Metab Toxicol 2012;8(11):1377-86.
  13. Semen plantaginis in: WHO Monographs on Selected Medicinal Plants, volume 1. World Health Organization, Geneva, 1999. Available at http://apps.who.int/medicinedocs/en/d/Js2200e/. Accessed November 26, 1026.
  14. Code of Federal Regulations, Title 21 (21CFR 101.17). Food labeling warning, notice, and safe handling statements. Available at www.ecfr.gov/cgi-bin/text-idx?SID=20f647d3b74161501f46564b915b4048&mc=true&node=se21.2.101_117&rgn=div8. Accessed December 3, 2
  15. Code of Federal Regulations, Title 21 (21CFR 201.319). Specific labeling requirements - water-soluble gums, hydrophilic gums, and hydrophilic mucilloids. Available at www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=201.319. Accessed Dece
  16. Diez R, Garcia JJ, Diez MJ, Sierra M, Sahagun AM, Fernandez N. Influence of Plantago ovata husk (dietary fiber) on the bioavailability and other pharmacokinetic parameters of metformin in diabetic rabbits. BMC Complement Altern Med. 2017 Jun 7;17(1):298. PubMed
  17. Chiu AC, Sherman SI. Effects of pharmacological fiber supplements on levothyroxine absorption. Thyroid. 1998;8(8):667-71. PubMed
  18. Merrick C, Madden CA, Capurso NA. A Case of Blunted Orally Disintegrating Olanzapine Effect Due to Coadministered Psyllium. J Clin Psychiatry 2021;82(2):20cr13633. PubMed

See these in context on the Black Psyllium monograph →

Baobab 1 reference
  1. Martini M, Mistrello G, Amato S, et al. Anaphylaxis to baobab fruit: the paradox of "natural healthy food". Eur Ann Allergy Clin Immunol 2019;51(6):282-4. doi: 10.23822/EurAnnACI.1764-1489.91. PubMed

See these in context on the Baobab monograph →

Beta-glucans 11 references
  1. Katz, D. L., Nawaz, H., Boukhalil, J., Giannamore, V., Chan, W., Ahmadi, R., and Sarrel, P. M. Acute effects of oats and vitamin E on endothelial responses to ingested fat. Am.J.Prev.Med. 2001;20(2):124-129. PubMed
  2. Keenan, J. M., Pins, J. J., Frazel, C., Moran, A., and Turnquist, L. Oat ingestion reduces systolic and diastolic blood pressure in patients with mild or borderline hypertension: a pilot trial. J.Fam.Pract. 2002;51(4):369.
  3. Maki, K. C., Galant, R., Samuel, P., Tesser, J., Witchger, M. S., Ribaya-Mercado, J. D., Blumberg, J. B., and Geohas, J. Effects of consuming foods containing oat beta-glucan on blood pressure, carbohydrate metabolism and biomarkers of oxidative stress i
  4. Bergendiova, K., Tibenska, E., and Majtan, J. Pleuran (beta-glucan from Pleurotus ostreatus) supplementation, cellular immune response and respiratory tract infections in athletes. Eur.J.Appl.Physiol 2011;111(9):2033-2040.
  5. Talbott S, Talbott J. Effect of beta 1,3/1,6 glucan on respiratory tract infection symptoms and mood state in marathon athletes. J Sports Sci Med 2009;8(4):509-515.
  6. Feldman S, Schwartz HI Kalman DS Mayers A Kohrman HM Clemens R Krieger DR. Randomized phase II clinical trials of Wellmune WGP® for immune support during cold and flu season. The Journal of Applied Research 2009;9(1-2):30-42.
  7. McFarlin BK, Carpenter KC, Davidson T, McFarlin MA. Baker's yeast beta glucan supplementation increases salivary IgA and decreases cold/flu symptomatic days after intense exercise. J Diet Suppl. 2013;10(3):171-83. PubMed
  8. Jesenak M, Urbancek S, Majtan J, Banovcin P, Hercogova J. ß-Glucan-based cream (containing pleuran isolated from pleurotus ostreatus) in supportive treatment of mild-to-moderate atopic dermatitis. J Dermatolog Treat 2016;27(4):351-4.
  9. Mah E, Kaden VN, Kelley KM, Liska DJ. Beverage containing dispersible yeast ß-glucan decreases cold/flu symptomatic days after intense exercise: a randomized controlled trial. J Diet Suppl 2020;17(2):200-10. PubMed
  10. Zhong K, Liu Z, Lu Y, Xu X. Effects of yeast ß-glucans for the prevention and treatment of upper respiratory tract infection in healthy subjects: a systematic review and meta-analysis. Eur J Nutr. 2021. PubMed
  11. Cardenas FI, Mauguen A, Cheung IY, et al. Phase I trial of oral yeast-derived ß-glucan to enhance anti-GD2 immunotherapy of resistant high-risk neuroblastoma. Cancers (Basel) 2021;13(24):6265. PubMed

See these in context on the Beta-glucans monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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