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Dietary supplement

Cinnamon Extract with CinSulin 250 mg Ingredients & Drug Interactions

by Doctor's Best

Cinnamon Extract with CinSulin 250 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Cinnamon Extract with CinSulin 250 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Cinnamon Extract with CinSulin 250 mg is a dietary supplement by Doctor's Best with 1 active ingredient. Its ingredients are commonly taken for blood sugar support, digestive upset, antioxidant support.Based on those ingredients, 442 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are CinSulin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Cinnamon Extract with CinSulin 250 mg by Doctor's Best

Ask about any prescription or over-the-counter medication and we check it for interactions with Cinnamon Extract with CinSulin 250 mg by Doctor's Best — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Cinnamon Extract with CinSulin 250 mg by Doctor's Best

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product has one active ingredient: CinSulin, a cassia cinnamon extract at 250 mg per capsule. Cassia cinnamon is a dried bark commonly used in supplements for metabolic support.

The capsule itself is made from inactive ingredients — a cellulose-based shell, cellulose powder, silicon dioxide, and magnesium stearate — that help deliver the active ingredient but don't contribute to the supplement's effects.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Cassia Cinnamon's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: blood sugar and glucose metabolism support.
  • We looked for evidence on: Diabetes, Dyslipidemia, Impaired glucose tolerance (prediabetes), Obesity, Insulin sensitivity, Metabolic health.
  • The closest evidence on file: Cassia Cinnamon is rated "Insufficient Reliable Evidence To Rate" for Diabetes (Natural Medicines).
  • Also on file: Cassia Cinnamon is rated "Insufficient Reliable Evidence To Rate" for Dyslipidemia, Obesity, Impaired glucose tolerance (prediabetes).

The evidence we have doesn't establish that cassia cinnamon works for any of the conditions listed in the data — amenorrhea (absent periods), angina (chest pain), common cold, diabetes, diarrhea, or high cholesterol (dyslipidemia). Each condition shows insufficient reliable evidence to make a rating.

That means the studies done so far either haven't been strong enough or haven't shown consistent results. If you're considering this for a specific health goal, talk with your pharmacist or doctor about what the research actually supports.

The evidence, ingredient by ingredient Cassia Cinnamon

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Cassia cinnamon is generally well tolerated in food amounts — the level you'd get from cooking and flavoring. The concern is with supplement doses, especially if you take large amounts for a long time.

Because cassia cinnamon contains coumarin, very high doses (50–7,000 mg per day) can potentially damage the liver, though this risk goes away once you stop taking it. In clinical trials, people taking 360 mg to 12 grams daily for three months didn't show significant changes in liver enzymes, so a 250 mg daily dose appears relatively safer.

Side effects are rare. One person reported a rash in a trial, and there's one case of contact dermatitis in someone with a cinnamon allergy.

One person also had a low blood sugar episode (hypoglycemia), though it's unclear if cinnamon caused it. For pregnancy and breastfeeding, food amounts are fine, but avoid high-dose supplements because we don't have enough safety data.

Side effects, ingredient by ingredient Cassia Cinnamon

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Cassia Cinnamon.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 443 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your pharmacist before using this if you take diabetes medications (blood sugar could drop further) or drugs that can damage the liver. These interactions are rated Moderate.

No other interactions are documented for the ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This product is primarily for people interested in cassia cinnamon's potential metabolic effects, though evidence for specific benefits isn't established in our data. Be cautious if you take diabetes medications or drugs that stress your liver — this supplement may add to those effects.

Talk with your pharmacist before starting, especially if you're on any regular medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 24, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Cinnamon Extract with CinSulin 250 mg, straight from the product label.

Brand Doctor's Best
Barcode (UPC) 753950004634
Net contents 120 Veggie Cap(s)
Market status On market
Date entered into DSLD Jan 24, 2024
DSLD ID 302648
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Cinnamon Extract with CinSulin 250 mg by Doctor's Best, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Veggie Capsule(s)
Maximum serving Sizes:
2 Veggie Capsule(s)
Servings per container
60
UPC/BARCODE
753950004634
IngredientAmount% DV
CinSulin500 mg--

Other ingredients: Hypromellose, Microcrystalline Cellulose, Silicon Dioxide, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Doctor's Best Cinnamon with CinSulin is a patented water extract of cinnamon.

Formulation

Cinnamon has been shown to help enhance insulin function and aid in more efficient glucose metabolism. It also helps lower blood glucose levels and reduce oxidative stress. One dose of Doctor's Best Cinnamon capsules is equivalent to 10 common cinnamon capsules (500 mg). Helps maintain healthy blood sugar levels within the normal range

Helps maintain healthy blood sugar levels within the normal range

Vegan

Non-Gmo Gluten free Soy free

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Brand IP Statement(s)

Doctor's Best Science-based nutrition

CinSulin is a registered trademark of BJTA Nutrition & Healthcare Prods. Co. and is licensed uinder US Patents 6200569, 8304000, 8329232

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested adult use: Take 2 capsules daily with food, or as recommended by a nutritionally informed physician.

Storage

Store in a cool dry place.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Cinnamon Extract with CinSulin 250 mg by Doctor's Best label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Cinnamon Extract with CinSulin 250 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Cinnamon Extract with CinSulin 250 mg by Doctor's Best

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Veggie Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

CinSulin

Interacts with
442 drugs
500 mg per serving Form: Cinnamon bark extract

Cassia cinnamon is the common, inexpensive cinnamon used in cooking, and it is also taken as a supplement, most often for blood sugar support. The evi...

CinSulin monograph & interactions

Other (inactive) ingredients: Hypromellose, Microcrystalline Cellulose, Silicon Dioxide, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Cinnamon Extract with CinSulin 250 mg by Doctor's Best Drug Interactions

Want to check YOUR meds against Cinnamon Extract with CinSulin 250 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
442Drugs
442 Moderate

Ingredients driving the most interactions

CinSulin 442

Individual Drug Interactions

The ingredients in Cinnamon Extract with CinSulin 250 mg interact with 442 drugs. Click any drug to see the details.

1 of the 1 ingredient in Cinnamon Extract with CinSulin 250 mg interact with drugs. Each result below shows which ingredient is responsible. CinSulin

Each ingredient & the kinds of drugs it affects

For each ingredient in Cinnamon Extract with CinSulin 250 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

CinSulin2 drug types · 442 drugs

Antidiabetes Drugs

Theoretically, cassia cinnamon may have additive effects with antidiabetes drugs.
Cassia cinnamon may lower blood glucose levels, and have additive effects in patients treated with antidiabetic agents. Dose adjustments to diabetes medications might be necessary.

Likelihood Possible Evidence B
Hepatotoxic Drugs

Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
There is some concern that ingesting large amounts of cassia cinnamon for an extended duration might cause hepatotoxicity in some people. Cassia cinnamon contains coumarin, which can cause hepatotoxicity in animal models. In humans, very high doses of coumarin from 50-7000 mg/day can result in hepatotoxicity that resolves when coumarin use is discontinued. Lower amounts might also cause liver problems in sensitive people, such as those with liver disease or those taking potentially hepatotoxic agents.

Likelihood Possible Evidence D
CinSulin full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Cinnamon Extract with CinSulin 250 mg, from the product label.

Doctor's Best

See all Doctor's Best products
Name
Doctor's Best, Inc.
City
Tustin
State
California
ZipCode
92780
Phone Number
(800) 777-2474
Web Address
drbvitamins.com
Pharmacist Counseling Corner

Cinnamon Extract with CinSulin 250 mg by Doctor's Best: Common Questions

Does Cinnamon Extract with CinSulin 250 mg by Doctor's Best interact with any medications?
Yes. Based on its ingredients, Cinnamon Extract with CinSulin 250 mg has a known interaction with 442 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Cinnamon Extract with CinSulin 250 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this with my diabetes medication?
Not without checking with your doctor or pharmacist first. Cassia cinnamon may lower blood sugar on its own, and combining it with diabetes drugs could lower it too much. Your dose might need adjusting.
Is it safe to take for a long time?
Food amounts of cinnamon are fine long-term, but supplement doses high in coumarin may harm your liver over extended use. A 250 mg daily dose appears relatively safer based on clinical trials, but talk to your pharmacist about your situation.
What does this supplement actually do?
We don't have strong evidence that cassia cinnamon works for any specific condition — that includes blood sugar control, cholesterol, or the other uses listed. The evidence falls short of what we'd call reliable.
Is it safe during pregnancy?
Food amounts are fine, but avoid high-dose supplements during pregnancy because we don't have enough safety data. Talk with your doctor or pharmacist about whether this product makes sense for you right now.
Are there any side effects I should know about?
Most people tolerate it well. Rarely, someone may get a rash or a skin reaction if allergic to cinnamon. One person had a low blood sugar episode, though we can't confirm the supplement caused it.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Cinnamon Extract with CinSulin 250 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Cinnamon Extract with CinSulin 250 mg label
Go deeper

The Full Monographs Behind Cinnamon Extract with CinSulin 250 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Cassia Cinnamon

Interacts with 442 drugs

Cassia cinnamon is the common, inexpensive cinnamon used in cooking, and it is also taken as a supplement, most often for blood sugar support. The evidence for its health benefits is mixed a...

Read the full Cassia Cinnamon monograph →
Sources

Sources & How We Checked

Cinnamon Extract with CinSulin 250 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 20 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Cassia Cinnamon 20 references
  1. Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
  2. Khan A, Safdar M, Ali Khan M, et al. Cinnamon improves glucose and lipids of people with type 2 diabetes. Diabetes Care 2003;26:3215-8. PubMed
  3. De Benito V, Alzaga R. Occupational allergic contact dermatitis from cassia (Chinese cinnamon) as a flavouring agent in coffee. Contact Dermatitis 1999;40:165. PubMed
  4. Drake TE, Maibach HI. Allergic contact dermatitis and stomatitis caused by a cinnamic aldehyde-flavored toothpaste. Arch Dermatol 1976;112:202-3.
  5. Press release. Cinnamon capsules to reduce blood sugar are medicinal products! Efficacy has not been scientifically proven - some products contain high levels of coumarin. Federal Institute of Risk Assessment (BfM), Germany, November 11, 2006. Available a
  6. Felter SP, Vassallo JD, Carlton BD, Daston GP. A safety assessment of coumarin taking into account species-specificity of toxicokinetics. Food Chem Toxicol 2006;44:462-75. PubMed
  7. Crawford P. Effectiveness of cinnamon for lowering hemoglobin A1C in patients with type 2 diabetes: a randomized, controlled trial. J Am Board Fam Med 2009;22:507-12. PubMed
  8. Akilen, R., Tsiami, A., Devendra, D., and Robinson, N. Glycated haemoglobin and blood pressure-lowering effect of cinnamon in multi-ethnic Type 2 diabetic patients in the UK: a randomized, placebo-controlled, double-blind clinical trial. Diabet.Med. 2010; PubMed
  9. Lu T, Sheng H Wu J Cheng Y Zhu J Chen Y. Cinnamon extract improves fasting blood glucose and glycosylated hemoglobin level in Chinese patients with type 2 diabetes. Nutr Res. 2012;32(6):408-412. PubMed
  10. Choi, J., Lee, K. T., Ka, H., Jung, W. T., Jung, H. J., and Park, H. J. Constituents of the essential oil of the Cinnamomum cassia stem bark and the biological properties. Arch Pharm Res 2001;24(5):418-423.
  11. Altschuler JA, Casella SJ, MacKenzie TA, Curtis KM. The effect of cinnamon on A1C among adolescents with type 1 diabetes. Diabetes Care 2007;30(4):813-6. PubMed
  12. Stoecker BR, Zhan Z, Luo R, et al. Cinnamon extract lowers blood glucose in hyperglycemic subjects. FASEB J. 2010;22:722.1 (Abstract only). DOI
  13. Admani S, Hill H, Jacob SE. Cinnamon Sugar Scrub Dermatitis: "Natural" Is Not Always Best. Pediatr Dermatol. 2017;34(1):e42-e43. PubMed
  14. Isaac-Renton M, Li MK, Parsons LM. Cinnamon spice and everything not nice: many features of intraoral allergy to cinnamic aldehyde. Dermatitis. 2015;26(3):116-21. PubMed
  15. Vandersall A, Katta R. Eyelid dermatitis as a manifestation of systemic contact dermatitis to cinnamon. Dermatitis. 2015 Jul-Aug;26(4):189. PubMed
  16. Wickenberg J, Lindstedt S, Nilsson J, Hlebowicz J. Cassia cinnamon does not change the insulin sensitivity or the liver enzymes in subjects with impaired glucose tolerance. Nutr J 2014 Sep 24;13:96. PubMed
  17. Brancheau D, Patel B, Zughaib M. Do cinnamon supplements cause acute hepatitis? Am J Case Rep 2015;16:250-4. PubMed
  18. Shekarchizadeh-Esfahani P, Heydarpour F, Izadi F, Jalili C. The effect of cinnamon supplementation on liver enzymes in adults: A systematic review and meta-analysis of randomized controlled trials. Complement Ther Med 2021;58:102699. PubMed
  19. Bernaola J, Valverde-Monge M, Otal-Buesa M, Cullen D, Heras-Mendaza F. Cinnamon allergic contact cheilitis. Contact Dermatitis 2023;88(5):418-419. PubMed
  20. Patel K, Howard M, Tate B. Cheilitis caused by allergic contact dermatitis to cinnamon in chai tea: A case report. Contact Dermatitis 2023;88(3):239-240. PubMed

See these in context on the Cassia Cinnamon monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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