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Dietary supplement

Circu Caps Higher Dose Ingredients & Drug Interactions

by Sanhelios

Circu Caps Higher Dose label
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Softgel Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Circu Caps Higher Dose against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Circu Caps Higher Dose is a dietary supplement by Sanhelios with 1 active ingredient. Its ingredients are commonly taken for chronic venous insufficiency, varicose veins, leg swelling and heaviness.Based on those ingredients, 158 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Butcher’s Broom dried extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Circu Caps Higher Dose by Sanhelios

Ask about any prescription or over-the-counter medication and we check it for interactions with Circu Caps Higher Dose by Sanhelios — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Circu Caps Higher Dose by Sanhelios

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Circu Caps Higher Dose is a single-ingredient softgel. The active ingredient is butcher's broom dried extract, a plant-based substance traditionally used to support circulation and address symptoms related to poor blood flow in the legs.

The capsule itself is made from gelatin, glycerol, and water.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: support normal circulation.
  • We looked for evidence on: Chronic venous insufficiency (CVI), Varicose veins, Hemorrhoids, venous insufficiency, leg swelling.
  • The strongest evidence on file: Butcher's Broom is rated "Possibly Effective" for Chronic venous insufficiency (CVI) (Natural Medicines).
  • Also on file: Butcher's Broom is rated "Insufficient Reliable Evidence To Rate" for Hemorrhoids, Varicose veins.

Butcher's broom is possibly effective for chronic venous insufficiency (CVI)—the condition where veins struggle to return blood from the legs to the heart. For other uses listed on this product, the evidence isn't established: there isn't enough reliable data to rate it for diabetic retinopathy, hemorrhoids, orthostatic hypotension (dizziness when standing), or lymphedema.

The evidence, ingredient by ingredient Butcher's Broom

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Butcher's broom is generally well tolerated when taken by mouth short-term in healthy adults, but long-term safety data is limited. The most common side effects are digestive: diarrhea, nausea, vomiting, heartburn, indigestion, and stomach inflammation.

In rare cases, oral use has caused severe vomiting and diarrhea leading to dehydration and electrolyte imbalances. During pregnancy, the safety data advises against use.

The same holds for breastfeeding—there isn't enough information to know if it's safe, so it's best avoided. If you're pregnant, nursing, or planning to become pregnant, talk with your doctor or pharmacist before taking this product.

Side effects, ingredient by ingredient Butcher's Broom

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Butcher's Broom.
  • The most serious interaction on file is rated Moderate.
  • For scale: 158 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take alpha-adrenergic agonists (such as certain decongestants and some blood pressure or attention medications) or alpha-adrenergic antagonists (a class of blood pressure medications), check your exact drugs with your doctor or pharmacist before starting this product—butcher's broom may change how they work.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Circu Caps may be worth considering if you have chronic venous insufficiency and are looking for a plant-based option. If you take any blood pressure medications or decongestants, check your exact drugs with your doctor or pharmacist before starting—butcher's broom can interact with adrenaline-like medications.

Those who are pregnant or breastfeeding should avoid it. Run through your full medication list on this page before you add it in.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 22, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Circu Caps Higher Dose, straight from the product label.

Brand Sanhelios
Barcode (UPC) 364031207051
Net contents 50 Softgel Capsule(s)
Market status On market
Date entered into DSLD May 22, 2015
DSLD ID 45174
Product type Botanical
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Circu Caps Higher Dose by Sanhelios, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
UPC/BARCODE
364031207051
IngredientAmount% DV
Butcher’s Broom dried extract120 mg--

Other ingredients: Gelatin, Glycerol, Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Helps support normal circulation

Blister pack ensures freshness.

The ultimate in circulation support Higher Dose – Equivalent to 900 mg Butcher’s Broom rhizome The difference is the dosage.

So all you need is one capsule daily to help support normal circulation – including circulation in the sensitive tissues of the rectum. Can even be used if you experience occasional heaviness in the legs.

Product of Germany

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Precautions

Do not use if blister pack is broken.

Cautions: Keep out of reach of children.

Storage

Store in cool, dry place.

Formula

Circu Caps(TM) Higher Dose contains a more concentrated dried extract equivalent to 900 mg Butcher’s Broom rhizome per capsule. It’s 3 times stronger per serving than regular Circu Caps(TM).

Butcher's Broom

Suggested/Recommended/Usage/Directions

DIRECTIONS: Take one capsule per day with a meal.

Formulation

This formula contains no sugar, no preservatives, no artificial coloring, no artificial flavoring.

General

2882090 1406

Seals/Symbols

Premium Quality GMP Made in Germany

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Circu Caps Higher Dose by Sanhelios label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Circu Caps Higher Dose label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Circu Caps Higher Dose by Sanhelios

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formSoftgel Capsule Amounts shown are per serving.

Butcher’s Broom dried extract

Interacts with
158 drugs
120 mg per serving

Butcher's broom is a plant extract most often used for circulation problems in the legs, such as chronic venous insufficiency, where some evidence sug...

Butcher’s Broom dried extract monograph & interactions

Other (inactive) ingredients: Gelatin, Glycerol, Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Circu Caps Higher Dose by Sanhelios Drug Interactions

Want to check YOUR meds against Circu Caps Higher Dose?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

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158Drugs
158 Moderate

Ingredients driving the most interactions

Butcher’s Broom dried extract 158

Individual Drug Interactions

The ingredients in Circu Caps Higher Dose interact with 158 drugs. Click any drug to see the details.

1 of the 1 ingredient in Circu Caps Higher Dose interact with drugs. Each result below shows which ingredient is responsible. Butcher’s Broom dried extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Circu Caps Higher Dose with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Butcher’s Broom dried extract2 drug types · 158 drugs

Alpha-Adrenergic Agonists

Theoretically, butcher's broom might increase the effects and adverse effects of alpha-adrenergic agonists.
Animal and in vitro studies show that butcher's broom has alpha-adrenergic agonist effects.

Likelihood Possible Evidence D
Alpha-Adrenergic Antagonists

Theoretically, butcher's broom might reduce the effects of alpha-adrenergic antagonists.
Animal and in vitro studies show that butcher's broom has alpha-adrenergic agonist effects.

Likelihood Possible Evidence D
Butcher’s Broom dried extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Circu Caps Higher Dose, from the product label.

Sanhelios

See all Sanhelios products
Name
Bioforce USA
City
Ghent
State
NY
ZipCode
12075
Pharmacist Counseling Corner

Circu Caps Higher Dose by Sanhelios: Common Questions

Does Circu Caps Higher Dose by Sanhelios interact with any medications?
Yes. Based on its ingredients, Circu Caps Higher Dose has a known interaction with 158 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Circu Caps Higher Dose contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is butcher's broom and why is it in this product?
Butcher's broom is a plant extract used to support circulation and help with symptoms of poor blood flow in the legs, especially a condition called chronic venous insufficiency. That's the main use backed by available evidence.
Can I take this if I'm pregnant or breastfeeding?
No. Safety hasn't been established during pregnancy, so it's best avoided. The same goes for breastfeeding—there isn't enough information to know if it's safe for your baby. Talk with your doctor or pharmacist about safer options.
What side effects might I experience?
The most common ones are digestive: diarrhea, nausea, vomiting, heartburn, indigestion, and stomach inflammation. These are usually mild and short-term, but if you have severe vomiting or diarrhea that won't stop, contact your doctor.
Does this product work for hemorrhoids or other vein problems?
The evidence is strongest for chronic venous insufficiency. For hemorrhoids, diabetic retinopathy, orthostatic hypotension, and lymphedema, there isn't enough reliable data to say whether it works.
Are there any fillers or other ingredients I should know about?
The capsule itself is made from gelatin, glycerol, and water. The active ingredient is butcher's broom extract. If you have allergies to gelatin or glycerol, let your pharmacist know.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Circu Caps Higher Dose label
Go deeper

The Full Monographs Behind Circu Caps Higher Dose’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Butcher's Broom

Interacts with 158 drugs

Butcher's broom is a plant extract most often used for circulation problems in the legs, such as chronic venous insufficiency, where some evidence suggests it may help reduce swelling and di...

Read the full Butcher's Broom monograph →
Sources

Sources & How We Checked

Circu Caps Higher Dose's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 8 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Butcher's Broom 8 references
  1. Beltramino R, Penenory A, Buceta AM. An open-label, randomized multicenter study comparing the efficacy and safety of Cyclo 3 Fort versus hydroxyethyl rutoside in chronic venous lymphatic insufficiency. Angiology 2000;51:535-44.. PubMed
  2. Redman DA. Ruscus aculeatus (butcher's broom) as a potential treatment for orthostatic hypotension, with a case report. J Altern Complement Med 2000;6:539-49..
  3. Landa, N., Aguirre, A., Goday, J., Raton, J. A., and Diaz-Perez, J. L. Allergic contact dermatitis from a vasoconstrictor cream. Contact Dermatitis 1990;22(5):290-291. PubMed
  4. Cluzan, R. V., Alliot, F., Ghabboun, S., and Pascot, M. Treatment of secondary lymphedema of the upper limb with CYCLO 3 FORT. Lymphology 1996;29(1):29-35.
  5. Parrado F, Buzzi A. A study of the efficacy and tolerability of a preparation containing Ruscus aculeatus in the treatment of chronic venous insufficiency of the lower limbs. Clin Drug Invest 1999;18(4):255-61. DOI
  6. Sadarmin PP, Timperley J. An unusual case of Butcher's Broom precipitating diabetic ketoacidosis. J Emerg Med 2013;45(3):e63-e65. PubMed
  7. Ramirez-Hernandez M, Garcia-Selles J, Merida-Fernandez C, Martinez-Escribano JA. Allergic contact dermatitis to ruscogenins. Contact Dermatitis 2006;54(1):60. PubMed
  8. European Medicines Agency. Assessment report on Ruscus Aculeatus L rhizome. EMEA/HMPC/261939/2007. London, September 4, 2008. Available at: http://www.ema.europa.eu/docs/en_GB/document_library/Herbal_-_HMPC_assessment_report/2009/12/WC500018288.pdf. Acces

See these in context on the Butcher's Broom monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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