Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

CLA Ingredients & Drug Interactions

by OL Olympian Labs Performance Sports Nutrition

CLA label
See full label image
Softgel Capsule Category: Fat/fatty Acid
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Oct 7, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking CLA against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

CLA is a dietary supplement by OL Olympian Labs Performance Sports Nutrition with 1 active ingredient. Its ingredients are commonly taken for heart and cholesterol support, skin moisturizing, menstrual cramps.Based on those ingredients, 208 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Safflower Oil Concentrate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against CLA by OL Olympian Labs Performance Sports Nutrition

Ask about any prescription or over-the-counter medication and we check it for interactions with CLA by OL Olympian Labs Performance Sports Nutrition — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of CLA by OL Olympian Labs Performance Sports Nutrition

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Oct 8, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 5 active ingredients.
  • “Safflower Oil Concentrate” is listed as a grouped ingredient — the label gives one combined amount (3 Gram(s)) without saying how much of each component you get.

The active ingredients listed are stearic acid, conjugated linoleic acid (CLA), oleic acid, palmitic acid, linoleic acid, and safflower oil concentrate. Our data holds a monograph only for oleic acid, which is a fat found in foods like olive oil.

For the others, our data does not describe their specific roles in this product. The inactive ingredients are gelatin, glycerin, water, caramel, and carob.

These are non-active components that make up the softgel capsule and its contents.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Oleic Acid's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: reduce body fat and increase lean muscle mass.
  • We looked for evidence on: Obesity, Overweight, Body composition, Sarcopenia, Fat loss.
  • The closest evidence on file: Oleic Acid is rated "Insufficient Reliable Evidence To Rate" for Obesity (Natural Medicines).

Our data holds effectiveness ratings of Possibly Effective for hypercholesterolemia (high cholesterol) and for coronary heart disease (CHD). These ratings are on file for the product's uses, but our data does not tie each rating to a single ingredient, so we cannot say which ingredient is responsible.

Possibly Effective means there is some supporting evidence, but it is not firmly established. Talk with your doctor about whether this product fits your needs.

The evidence, ingredient by ingredient Safflower Oleic Acid

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

The safety notes on file for oleic acid describe food amounts, such as those in olive oil, as generally well tolerated. They also note that concentrated supplement doses are not well studied and lack good safety data.

We have no adverse effects on file for this product. Our data does not give usable pregnancy or breastfeeding guidance for these ingredients, so there isn't enough information to know either way.

Talk with your doctor or pharmacist for advice that fits your situation.

Side effects, ingredient by ingredient Safflower Oleic Acid

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Oleic Acid.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Double-check any antidiabetes drugs (medications that lower blood sugar) before taking this product. This is the only documented interaction category for the ingredients we could check, and it carries a Moderate severity rating.

We hold no interaction data for several other ingredients, so search your exact medications on this page and confirm with your own pharmacist.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and some safety-information gaps remain.

This product may be worth considering if you are looking for a supplement tied to cholesterol or heart health and have discussed it with your doctor. If you have diabetes or take any blood sugar medication, be especially careful, because oleic acid may increase their effects.

Talk it over with your own doctor or pharmacist before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about CLA, straight from the product label.

Brand OL Olympian Labs Performance Sports Nutrition
Barcode (UPC) 710013031150
Net contents 210 Softgel(s)
Market status On market
Date entered into DSLD Mar 25, 2025
DSLD ID 326653
Product type Fat/fatty Acid
Supplement form Softgel Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), No Allergies, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for CLA by OL Olympian Labs Performance Sports Nutrition, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Softgel(s)
Maximum serving Sizes:
3 Softgel(s)
Servings per container
70
UPC/BARCODE
710013031150
IngredientAmount% DV
Calories30 Calorie(s)--
Stearic Acid0 NP--
Calories from Fat27 Calorie(s)--
Total Fat3 Gram(s)5%
Conjugated Linoleic Acid0 NP--
Oleic Acid0 NP--
Palmitic Acid0 NP--
Linoleic Acid0 NP--
Safflower Oil Concentrate3 Gram(s)--

Other ingredients: Gelatin, Glycerin, Water, Caramel, Carob

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

CLA (Conjugated Linoleic Acid) is a targeted, stimulant free solution to help maximize your fitness efforts, reduce body fat and increase lean muscle mass. Studies suggest CLA works by increasing your metabolic rate to help burn calories and pushing glucose (blood sugar) into muscle cells instead of letting it turn into body fat. CLA, when used in conjunction with a regimented diet and exercise plan, helps you get the muscle tone you want. CLA can also be stacked with additional weight management products.

CLA 3000mg per serving

Formulation

Olypian Labs, Inc. products are made with the highest quality ingredients and manufactured according to current Good Manufacturing Practices (cGMP).

Gluten Free Allergen Free Non GMO We do not use ingredients that were produced using modern biotechnology

May help reduce body fat Supports lean muscle mass May increase metabolic rate Muscle growth Fat burner

Made in USA

Precautions

Caution: If you are pregnant or nursing, have a medical condition, or are taking medication, consult your healthcare professional before using this or any other nutritional supplement.

Discontinue use if allergic reaction occurs.

Keep out of reach of children.

Prop 65 Warning for California residents Warning: This product can expose you to chemicals, including lead, cadmium, arsenic, and mercury, which are known to the State of California to cause cancer and birth defects or other reproductive harm. For more information, go to www.P65Warnings.ca.gov.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Storage

Store in a cool, dry place.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Daily Suggested use: As a dietary Supplement, take three (3) softgels daily, or as directed by a healthcare professional.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

CLA by OL Olympian Labs Performance Sports Nutrition label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

CLA label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in CLA by OL Olympian Labs Performance Sports Nutrition

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size3 Softgel(s) Dosage formSoftgel Capsule Servings per container70 Amounts shown are per serving.

Safflower Oil Concentrate

Interacts with
208 drugs
3 Gram(s) per serving

Safflower is a thistle-like plant used mainly for its seed oil (a common cooking oil) and its colorful flowers. Safflower oil is a reasonable source o...

Safflower Oil Concentrate monograph & interactions
  • › Stearic Acid
  • › Conjugated Linoleic Acid
  • › Oleic Acid
  • › Palmitic Acid
  • › Linoleic Acid

Other (inactive) ingredients: Gelatin, Glycerin, Water, Caramel, Carob. These complete the product’s ingredient list but are not active constituents.

Interaction report

CLA by OL Olympian Labs Performance Sports Nutrition Drug Interactions

Want to check YOUR meds against CLA?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
208Drugs
208 Moderate

Ingredients driving the most interactions

Safflower Oil Concentrate 208

Individual Drug Interactions

The ingredients in CLA interact with 208 drugs. Click any drug to see the details.

1 of the 1 ingredient in CLA interact with drugs. Each result below shows which ingredient is responsible. Safflower Oil Concentrate

Each ingredient & the kinds of drugs it affects

For each ingredient in CLA with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Safflower Oil Concentrate3 drug types · 208 drugs

Anticoagulant/Antiplatelet Drugs

High doses of safflower oil might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Small clinical studies show that taking safflower oil, approximately 55 grams daily for 2-3 weeks, decreases platelet aggregation. However, taking lower doses of safflower oil, such as 5 grams daily for 4 weeks, does not seem to affect platelet function. In one case report, a 74-year-old male stabilized on warfarin developed urinary tract bleeding and an elevated INR after taking a safflower extract 20 grams daily for 14 days.

Likelihood Possible Evidence B
Antidiabetes Drugs

Theoretically, safflower oil might alter the effects of antidiabetes drugs.
Some clinical research shows that taking safflower oil 10 grams daily for 3 weeks can increase fasting blood glucose in patients with type 2 diabetes. However, clinical research in patients with metabolic syndrome with or without impaired glucose tolerance shows that taking safflower oil 8 grams daily for 12 weeks reduces fasting glucose levels by around 8 mg/dL. Some clinical research also shows that taking safflower oil 8 grams daily for 16 weeks does not affect fasting glucose levels in patients with type 2 diabetes.

Likelihood Possible Evidence B
Warfarin

Theoretically, safflower oil might increase the risk of bleeding when taken with warfarin.
In one case report, a 74-year-old male stabilized on warfarin developed urinary tract bleeding and an elevated INR after taking a safflower extract 20 grams daily for 14 days.

Likelihood Possible Evidence D
Safflower Oil Concentrate full monograph & interactions
The maker

Brand information

Manufacturer and brand details for CLA, from the product label.

OL Olympian Labs Performance Sports Nutrition

See all OL Olympian Labs Performance Sports Nutrition products
Name
Olympian Labs, Inc.
City
Phoenix
State
AZ
ZipCode
85027
Phone Number
1-800-473-5883
Web Address
www.olympianlabs.com
Pharmacist Counseling Corner

CLA by OL Olympian Labs Performance Sports Nutrition: Common Questions

Does CLA by OL Olympian Labs Performance Sports Nutrition interact with any medications?
Yes. Based on its ingredients, CLA has a known interaction with 208 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
CLA contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this product safe during pregnancy?
Our data does not give usable pregnancy guidance for this product, so there isn't enough information to know either way. Talk with your doctor or pharmacist for personalized advice before using it while pregnant.
What is oleic acid doing in this product?
Oleic acid is a fat found naturally in foods like olive oil. Our data describes its food amounts as generally well tolerated, but it does not describe its specific role in this softgel.
Does this product work for cholesterol?
Our data rates the product's uses for hypercholesterolemia (high cholesterol) and coronary heart disease as Possibly Effective. That means there is some evidence, but it is not firmly established.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if CLA is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

CLA label
Go deeper

The Full Monographs Behind CLA’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Safflower

Interacts with 208 drugs

Safflower is a thistle-like plant used mainly for its seed oil (a common cooking oil) and its colorful flowers. Safflower oil is a reasonable source of unsaturated fats, but strong proof tha...

Read the full Safflower monograph → Herb & supplement monograph

Oleic Acid

Interacts with 86 drugs

Oleic acid is a heart-healthy monounsaturated fat found mainly in olive oil, canola oil, avocados, and nuts. As part of a Mediterranean-style diet, it is widely viewed as a healthier replace...

Read the full Oleic Acid monograph →
Sources

Sources & How We Checked

CLA's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 15 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Oleic Acid 1 reference
  1. Madigan C, Ryan M, Owens D, et al. Dietary unsaturated fatty acids in type 2 diabetes: higher levels of postprandial lipoprotein on a linoleic acid-rich sunflower oil diet compared with an oleic acid-rich olive oil diet. Diabetes Care 2000;23:1472-7. PubMed

See these in context on the Oleic Acid monograph →

Safflower 14 references
  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  3. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  4. Borkman M, Chisholm DJ, Furler SM, et al. Effects of fish oil supplementation on glucose and lipid metabolism in NIDDM. Diabetes 1989;38:1314-9.. PubMed
  5. Amato, P. and Quercia, R. A. A historical perspective and review of the safety of lipid emulsion in pregnancy. Nutr Clin Pract. 1991;6(5):189-192. PubMed
  6. Demke, D. M., Peters, G. R., Linet, O. I., Metzler, C. M., and Klott, K. A. Effects of a fish oil concentrate in patients with hypercholesterolemia. Atherosclerosis 1988;70(1-2):73-80. PubMed
  7. Kaji, K., Yoshida, S., Nagata, N., Yamashita, T., Mizukoshi, E., Honda, M., Kojima, Y., and Kaneko, S. An open-label study of administration of EH0202, a health-food additive, to patients with chronic hepatitis C. J Gastroenterol. 2004;39(9):873-878. PubMed
  8. Kwon, J. S., Snook, J. T., Wardlaw, G. M., and Hwang, D. H. Effects of diets high in saturated fatty acids, canola oil, or safflower oil on platelet function, thromboxane B2 formation, and fatty acid composition of platelet phospholipids. Am.J.Clin.Nutr. PubMed
  9. Lloyd-Still, J. D., Simon, S. H., Wessel, H. U., and Gibson, L. E. Negative effects of oral fatty acid supplementation on sweat chloride in cystic fibrosis. Pediatrics 1979;64(1):50-52. DOI
  10. Challen, A. D., Branch, W. J., and Cummings, J. H. The effect of aspirin and linoleic acid on platelet aggregation, platelet fatty acid composition and haemostasis in man. Hum Nutr Clin Nutr 1983;37(3):197-208.
  11. Asp ML, Collene AL, Norris LE, Cole RM, Stout MB, Tang SY, Hsu JC, Belury MA. Time-dependent effects of safflower oil to improve glycemia, inflammation and blood lipids in obese, post-menopausal women with type 2 diabetes: a randomized, double-masked, cro
  12. Liu Y, Liu S, Shi Y, et al. Effects of safflower injection on the pharmacodynamics and pharmacokinetics of warfarin in rats. Xenobiotica. 2017 Oct 25:1-6. [Epub ahead of print] PubMed
  13. de Ataide EC, Reges Perales S, de Oliveira Peres MA, et al. Acute liver failure induced by Carthamus tinctorius oil: Case reports and literature review. Transplant Proc. 2018;50(2):476-477. PubMed
  14. Ruyvaran M, Zamani A, Mohamadian A, et al. Safflower (Carthamus tinctorius L.) oil could improve abdominal obesity, blood pressure, and insulin resistance in patients with metabolic syndrome: a randomized, double-blind, placebo-controlled clinical trial. PubMed

See these in context on the Safflower monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team