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Dietary supplement

Clay, Gray Powder Ingredients & Drug Interactions

by TerraVita Premium Collection

Clay, Gray Powder label
See full label image
Powder Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Clay, Gray Powder against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Clay, Gray Powder is a dietary supplement by TerraVita Premium Collection with 1 active ingredient. Its ingredients are commonly taken for detox and digestive complaints, skin care (masks, acne, irritation), diarrhea and upset stomach.Based on those ingredients, 3 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Clay, Gray, Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Clay, Gray Powder by TerraVita Premium Collection

Ask about any prescription or over-the-counter medication and we check it for interactions with Clay, Gray Powder by TerraVita Premium Collection — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Clay, Gray Powder by TerraVita Premium Collection

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product is a single active ingredient: gray clay powder. Oral clay has been studied for its potential to help with rotaviral diarrhea — a specific viral gut infection — and possibly reduce diarrhea caused by chemotherapy, though the evidence for the latter remains limited.

The powder contains no inactive ingredients or fillers listed.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Clay's overall clinical evidence instead.

Moderate

Some clinical evidence supports Clay for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Rotaviral diarrhea — rated "Possibly Effective" (Natural Medicines).

Gray clay is possibly effective for rotaviral diarrhea based on available evidence. For other uses like chemotherapy-related diarrhea and irritable bowel syndrome (IBS), the evidence we have isn't solid enough to rate whether it works.

If you're considering this product for one of those conditions, ask your doctor or pharmacist what the research currently supports for your specific situation.

The evidence, ingredient by ingredient Clay

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Short-term oral use of clay is generally well tolerated, with mild side effects like constipation, vomiting, or diarrhea reported by some people. The bigger concern is long-term or habitual use — clay that's taken regularly can carry heavy metals and may interfere with nutrient absorption, potentially leading to iron deficiency anemia, heart problems, muscle weakness, or nerve damage over time.

Safety data advises against using this product during pregnancy due to heavy-metal and nutrient-absorption risks. There isn't enough safety information to use clay by mouth while breastfeeding — talk with your pharmacist or doctor about whether it's right for you.

Side effects, ingredient by ingredient Clay

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Clay.
  • The most serious interaction on file is rated Moderate.
  • For scale: 3 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check if you use cimetidine (Tagamet) or quinine — both are moderate interactions that could reduce how well these medications work. Altogether, these interactions span 3 individual medications.

Since clay can bind to substances in your gut, separate this product from other medications by at least 2 hours.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Gray clay may help with rotaviral diarrhea in the short term, but it's not the right choice for long-term or habitual use because of the risk of heavy-metal exposure and nutrient problems. If you're pregnant or breastfeeding, avoid it.

Be sure to check your medications — especially cimetidine and quinine — before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 22, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Clay, Gray Powder, straight from the product label.

Brand TerraVita Premium Collection
Barcode (UPC) 064435110703
Net contents 4 Ounce(s)
Market status On market
Date entered into DSLD Jun 22, 2023
DSLD ID 290389
Product type Non-nutrient/non-botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Clay, Gray Powder by TerraVita Premium Collection, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.25 Teaspoon(s)
Maximum serving Sizes:
0.25 Teaspoon(s)
Servings per container
113
UPC/BARCODE
064435110703
IngredientAmount% DV
Clay, Gray, Powder1000 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

A Dietary Supplement

Brand IP Statement(s)

Copyright 2004 TerraVita - Distributed by ZooScape LLC, All Rights Reserved.

Suggested/Recommended/Usage/Directions

Directions Stir 1/4 of a teaspoon into a glass of water and consume 3 times daily, with meals.

General Statements

TerraVita is an exclusive line of premium natural products that use the finest, purest and most potent ingredients in the world. TerraVita's hallmarks are the highest possible standards of purity, potency, stability and freshness. All products are prepared with the greatest quality control, from raw materials through the entire manufacturing process, right up to the moment your product is sealed for freshness and shipped to you.

Please recycle!

FDA Disclaimer Statement

Statements not evaluated by FDA. Product not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Clay, Gray Powder by TerraVita Premium Collection label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Clay, Gray Powder label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Clay, Gray Powder by TerraVita Premium Collection

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.25 Teaspoon(s) Dosage formPowder Servings per container113 Amounts shown are per serving.

Clay, Gray, Powder

Interacts with
3 drugs
1000 mg per serving

Clay is a fine, mineral-rich earth (such as bentonite or kaolin) used on the skin and sometimes taken by mouth for digestive and 'detox' purposes. Top...

Clay, Gray, Powder monograph & interactions
Interaction report

Clay, Gray Powder by TerraVita Premium Collection Drug Interactions

Want to check YOUR meds against Clay, Gray Powder?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
3Drugs
3 Moderate

Ingredients driving the most interactions

Clay, Gray, Powder 3

Individual Drug Interactions

The ingredients in Clay, Gray Powder interact with 3 drugs. Click any drug to see the details.

1 of the 1 ingredient in Clay, Gray Powder interact with drugs. Each result below shows which ingredient is responsible. Clay, Gray, Powder

Each ingredient & the kinds of drugs it affects

For each ingredient in Clay, Gray Powder with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Clay, Gray, Powder2 drug types · 3 drugs

Cimetidine (Tagamet)

Preliminary clinical research suggests that clay might inhibit the absorption of cimetidine when taken simultaneously. Consumption of clay along with cimetidine might reduce the effectiveness of cimetidine therapy.

Likelihood Possible Evidence B
Quinine

In vitro evidence suggests that consuming clay reduces the bioavailability of quinine by about 30%. Theoretically, consumption of clay along with quinine might reduce the effectiveness of quinine therapy.

Likelihood Probable Evidence D
Clay, Gray, Powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Clay, Gray Powder, from the product label.

TerraVita Premium Collection

See all TerraVita Premium Collection products
Name
TerraVita Fine Whole Herbs
City
Brampton
State
Ontario
Pharmacist Counseling Corner

Clay, Gray Powder by TerraVita Premium Collection: Common Questions

Does Clay, Gray Powder by TerraVita Premium Collection interact with any medications?
Yes. Based on its ingredients, Clay, Gray Powder has a known interaction with 3 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Clay, Gray Powder contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
Safety data advises against using clay during pregnancy because of heavy-metal and nutrient-absorption risks. There also isn't enough safety data for breastfeeding — talk with your pharmacist or doctor for personalized advice.
What does this clay actually do?
It's possibly effective for rotaviral diarrhea, a specific viral gut infection. For other uses like diarrhea from chemotherapy or irritable bowel syndrome, we don't have solid evidence that it works.
What are the side effects?
Short-term use causes mild effects like constipation, vomiting, or diarrhea in some people. Long-term or habitual use is riskier — clay can carry heavy metals and interfere with nutrient absorption, potentially leading to anemia, heart problems, or nerve damage.
How long can I safely take this?
The evidence supports short-term use. Long-term or habitual clay intake carries serious risks including heavy-metal exposure, iron deficiency, and heart problems — don't use this product regularly without talking to your doctor first.
Why do I need to keep it away from my other medicines?
Clay can bind to medications and other substances in your gut, blocking their absorption and making them less effective. Keep this product at least 2 hours away from prescription medications.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Clay, Gray Powder is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Clay, Gray Powder label
Go deeper

The Full Monographs Behind Clay, Gray Powder’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Clay

Interacts with 3 drugs

Clay is a fine, mineral-rich earth (such as bentonite or kaolin) used on the skin and sometimes taken by mouth for digestive and 'detox' purposes. Topical use for masks and minor skin issues...

Read the full Clay monograph →
Sources

Sources & How We Checked

Clay, Gray Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 31 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Clay 31 references
  1. Gonzalez JJ, Owens W, Ungaro PC, et al. Clay ingestion: a rare cause of hypokalemia. Ann Intern Med 1982;97(1):65-6. PubMed
  2. Mengel CE, Carter WA, Horton ES. Geophagia with iron deficiency and hypokalemia. Cachexia Africana. Arch Intern Med 1964;114:470-4. PubMed
  3. Severance HW Jr, Holt T, Patrone NA, Chapman L. Profound muscle weakness and hypokalemia due to clay ingestion. South Med J 1988;81(2):272-4. PubMed
  4. Minnich V, Okcuoglu A, Tarcon Y, et al. Pica in Turkey. II. Effect of clay upon iron absorption. Am J Clin Nutr 1968;21(1):78-86.
  5. O'Rourke DE, Quinn JG, Nicholson JO, Gibson HH. Geophagia during pregnancy. Obstet Gynecol 1967;29(4):581-4.
  6. Edwards CE, McDonald S, Mitchell JK, et al. Effect of clay and cornstarch intake on women and their infants. J Amer Diet Assoc 1964;44:109-15. DOI
  7. Carpenter WM. Observations on Cachexia Africana, on habits and effects of dirt eating in negro race. New Orleans Med Surg J 1844;1:146-68.
  8. Ducrotte P, Dapoigny M, Bonaz B, Siproudhis L. Symptomatic efficacy of beidellitic montmorillonite in irritable bowel syndrome: a randomized, controlled trial. Aliment Pharmacol Ther 2005;21(4):435-44. PubMed
  9. Chang FY, Lu CL, Chen CY, Luo JC. Efficacy of dioctahedral smectite in treating patients of diarrhea-predominant irritable bowel syndrome. J Gastroenterol Hepatol 2007;22(12):2266-72. PubMed
  10. Blum M, Orton C, Rose L. The effect of starch ingestion on excessive iron association, abstracted. Ann Intern Med 1968;68:1165.
  11. Ukaonu C, Hill DA, Christensen F. Hypokalemic myopathy in pregnancy caused by clay ingestion. Obstet Gynecol 2003;102(5 Pt 2):1169-71. DOI
  12. Andrews PL, Horn CC. Signals for nausea and emesis: Implications for models of upper gastrointestinal diseases. Auton Neurosci 2006;125(1-2):100-15. PubMed
  13. Wang JS, Luo H, Billam M, et al. Short-term safety evaluation of processed calcium montmorillonite clay (NovaSil) in humans. Food Addit Contam 2005;22(3):270-9. PubMed
  14. Bateson EM, Lebroy T. Clay eating by Aboriginals of the Northern Territory. Med J Aust 1978;1 Suppl 1:1-3. PubMed
  15. Delaitre B, Lemaigre G, Acar JF, et al. [Necrotizing enteritis and geophagia]. Nouv Presse Med 1976;5(28):1743-6.
  16. Sanchez A JE. Perforation of the colon due to clay ball. Arch Surg 1978;113(7):906. PubMed
  17. Prasad AS, Halsted JA, Nadimi M. Syndrome of iron deficiency anemia, hepatospelenomegaly, hypogonadism, dwarfism and geophagia. Am J Med 1961;31:532-46.
  18. Bennett A, Stryjewski G. Severe hypokalemia caused by oral and rectal administration of bentonite in a pediatric patient. Pediatr Emerg Care 2006;22(7):500-2. PubMed
  19. Guinee VF. Pica and lead poisoning. Nutr Rev 1971;29(12):267-9. PubMed
  20. Getahun H, Lambein F, Vanhoorne M, Van der Stuyft P. Neurolathyrism risk depends on type of grass pea preparation and on mixing with cereals and antioxidants. Trop Med Int Health 2005;10(2):169-78. PubMed
  21. Trivedi TH, Daga GL, Yeolekar ME. Geophagia leading to hypokalemic quadriparesis in a postpartum patient. J Assoc Physicians India 2005;53:205-7.
  22. Fredj G, Farinotti R, Salvadori C, et al. [Topical digestive drugs with a clay base. Influence on the absorption of cimetidine]. Therapie 1986;41(1):23-5.
  23. Dominy NJ, Davoust E, Minekus M. Adaptive function of soil consumption: an in vitro study modeling the human stomach and small intestine. J Exp Biol 2004;207(Pt 2):319-24.
  24. Pariente EA, De La Garoullaye G. A multicenter comparative study of a mucilage (Karaya gum + PVPP) versus clay in functional intestinal disorders. Med Chir Dig 1994;23(3):193-9.
  25. Pérez-Gaxiola G, Cuello-García CA, Florez ID, Pérez-Pico VM. Smectite for acute infectious diarrhoea in children. Cochrane Database Syst Rev. 2018;4:CD011526. PubMed
  26. Kee BK, Morris JS, Slack RS, et al. A phase II, randomized, double blind trial of calcium aluminosilicate clay versus placebo for the prevention of diarrhea in patients with metastatic colorectal cancer treated with irinotecan. Support Care Cancer. 2015;2 PubMed
  27. Mitchell NJ, Kumi J, Aleser M, et al. Short-term safety and efficacy of calcium montmorillonite clay (UPSN) in children. Am J Trop Med Hyg. 2014;91(4):777-85. PubMed
  28. Gupta M, Sachdev A, Lehl SS, Singh K. Clay impaction causing acute dysphagia. BMJ Case Rep. 2013;2013. pii: bcr2013008929. PubMed
  29. Lin JX, Fan ZY, Lin Q, et al. A comparison of dioctahedral smectite and iodine glycerin cream with topical mouth rinse in treatment of chemotherapy induced oral mucositis: a pilot study. Eur J Oncol Nurs. 2015;19(2):136-41. PubMed
  30. Lai BY, Liang N, Cao HJ, et al. Pediatric Tui Na for acute diarrhea in children under 5 years old: A systematic review and meta-analysis of randomized clinical trials. Complement Ther Med. 2018;41:10-22. PubMed
  31. Schmidt C, Oxley Oxland J, Freercks R. A rare case of hypokalaemia and hypophosphataemia secondary to geophagia. BMJ Case Rep. 2021 May 12;14(5):e239322. PubMed

See these in context on the Clay monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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