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Dietary supplement

Clay, Green 450 mg Ingredients & Drug Interactions

by TerraVita Premium Collection

Clay, Green 450 mg label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Clay, Green 450 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Clay, Green 450 mg is a dietary supplement by TerraVita Premium Collection with 1 active ingredient. Its ingredients are commonly taken for detox and digestive complaints, skin care (masks, acne, irritation), diarrhea and upset stomach.Based on those ingredients, 3 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Clay, Green. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Clay, Green 450 mg by TerraVita Premium Collection

Ask about any prescription or over-the-counter medication and we check it for interactions with Clay, Green 450 mg by TerraVita Premium Collection — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Clay, Green 450 mg by TerraVita Premium Collection

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: green clay at 450 mg per capsule. The capsules themselves are made with gelatin and water as inactive ingredients.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Clay's overall clinical evidence instead.

Moderate

Some clinical evidence supports Clay for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Rotaviral diarrhea — rated "Possibly Effective" (Natural Medicines).

Green clay is possibly effective for rotaviral diarrhea (the kind caused by the rotavirus). For other uses—chemotherapy-related diarrhea and irritable bowel syndrome—we don't have enough reliable evidence to say whether it works or not.

The evidence, ingredient by ingredient Clay

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Orally, green clay is generally well tolerated over the short term, though some people experience mild constipation, vomiting, or diarrhea. The main safety concern is that oral clay can be contaminated with heavy metals.

Long-term or habitual ingestion carries more serious risks: iron deficiency anemia, heart problems including painful palpitations, and low potassium levels that may lead to muscle weakness. The safety data advises against taking green clay by mouth during pregnancy due to concerns about heavy-metal exposure and nutrient absorption.

There isn't enough data to know whether it's safe while breastfeeding, so talk with your doctor or pharmacist for personalized advice.

Side effects, ingredient by ingredient Clay

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Clay.
  • The most serious interaction on file is rated Moderate.
  • For scale: 3 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your pharmacist or use the tool below if you take cimetidine (Tagamet) or quinine. These are Moderate interactions where green clay may reduce how well the medication works.

We haven't checked green clay against all possible medications, so if you're on any other prescriptions, run them through the checker too.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Green clay may be considered for short-term relief of rotavirus diarrhea, but be cautious if you're pregnant—the data advises against it. If you take cimetidine or quinine, or any other medications, check them against this product first.

Long-term use isn't recommended because of potential heavy-metal buildup and serious side effects.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 21, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Clay, Green 450 mg, straight from the product label.

Brand TerraVita Premium Collection
Barcode (UPC) 064435110550
Net contents 100 Capsule(s)
Market status On market
Date entered into DSLD Feb 21, 2023
DSLD ID 285941
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Clay, Green 450 mg by TerraVita Premium Collection, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
100
UPC/BARCODE
064435110550
IngredientAmount% DV
Clay, Green450 mg--

Other ingredients: Gelatin, Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

A Dietary Supplement

Brand IP Statement(s)

Copyright 2004 TerraVita - Distributed by ZooScape LLC, All Rights Reserved.

Suggested/Recommended/Usage/Directions

Directions Take 1 capsule, 3 times daily, with meals.

General Statements

TerraVita is an exclusive line of premium natural products that use the finest, purest and most potent ingredients in the world. TerraVita's hallmarks are the highest possible standards of purity, potency, stability and freshness. All products are prepared with the greatest quality control, from raw materials through the entire manufacturing process, right up to the moment your product is sealed for freshness and shipped to you.

Please recycle!

FDA Disclaimer Statement

Statements not evaluated by FDA. Product not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Clay, Green 450 mg by TerraVita Premium Collection label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Clay, Green 450 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Clay, Green 450 mg by TerraVita Premium Collection

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container100 Amounts shown are per serving.

Clay, Green

Interacts with
3 drugs
450 mg per serving

Clay is a fine, mineral-rich earth (such as bentonite or kaolin) used on the skin and sometimes taken by mouth for digestive and 'detox' purposes. Top...

Clay, Green monograph & interactions

Other (inactive) ingredients: Gelatin, Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Clay, Green 450 mg by TerraVita Premium Collection Drug Interactions

Want to check YOUR meds against Clay, Green 450 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
3Drugs
3 Moderate

Ingredients driving the most interactions

Clay, Green 3

Individual Drug Interactions

The ingredients in Clay, Green 450 mg interact with 3 drugs. Click any drug to see the details.

1 of the 1 ingredient in Clay, Green 450 mg interact with drugs. Each result below shows which ingredient is responsible. Clay, Green

Each ingredient & the kinds of drugs it affects

For each ingredient in Clay, Green 450 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Clay, Green2 drug types · 3 drugs

Cimetidine (Tagamet)

Preliminary clinical research suggests that clay might inhibit the absorption of cimetidine when taken simultaneously. Consumption of clay along with cimetidine might reduce the effectiveness of cimetidine therapy.

Likelihood Possible Evidence B
Quinine

In vitro evidence suggests that consuming clay reduces the bioavailability of quinine by about 30%. Theoretically, consumption of clay along with quinine might reduce the effectiveness of quinine therapy.

Likelihood Probable Evidence D
Clay, Green full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Clay, Green 450 mg, from the product label.

TerraVita Premium Collection

See all TerraVita Premium Collection products
Name
TerraVita Fine Whole Herbs
City
Brampton
State
Ontario
Pharmacist Counseling Corner

Clay, Green 450 mg by TerraVita Premium Collection: Common Questions

Does Clay, Green 450 mg by TerraVita Premium Collection interact with any medications?
Yes. Based on its ingredients, Clay, Green 450 mg has a known interaction with 3 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Clay, Green 450 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is green clay safe to use long-term?
The data suggests caution with long-term use. While short-term oral use is generally well tolerated, habitual clay ingestion has been linked to iron deficiency anemia, heart problems like painful palpitations, low potassium levels, and heavy-metal buildup. Talk to your pharmacist about how long you should use it.
Can I take this while pregnant?
No. The safety data advises against taking green clay by mouth during pregnancy because of concerns about heavy-metal exposure and how it might affect nutrient absorption.
Can I take this while breastfeeding?
There isn't enough safety data to know either way. Talk with your doctor or pharmacist for personalized advice before using it.
What side effects might I experience?
Short-term use is generally mild: constipation, vomiting, or diarrhea are most common. Long-term use carries more serious risks like anemia, heart palpitations, and low potassium levels.
Does green clay really help with diarrhea?
It's possibly effective for rotavirus diarrhea specifically. For diarrhea caused by chemotherapy or for irritable bowel syndrome, we don't have enough reliable evidence to say whether it works.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Clay, Green 450 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Clay, Green 450 mg label
Go deeper

The Full Monographs Behind Clay, Green 450 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Clay

Interacts with 3 drugs

Clay is a fine, mineral-rich earth (such as bentonite or kaolin) used on the skin and sometimes taken by mouth for digestive and 'detox' purposes. Topical use for masks and minor skin issues...

Read the full Clay monograph →
Sources

Sources & How We Checked

Clay, Green 450 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 31 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Clay 31 references
  1. Gonzalez JJ, Owens W, Ungaro PC, et al. Clay ingestion: a rare cause of hypokalemia. Ann Intern Med 1982;97(1):65-6. PubMed
  2. Mengel CE, Carter WA, Horton ES. Geophagia with iron deficiency and hypokalemia. Cachexia Africana. Arch Intern Med 1964;114:470-4. PubMed
  3. Severance HW Jr, Holt T, Patrone NA, Chapman L. Profound muscle weakness and hypokalemia due to clay ingestion. South Med J 1988;81(2):272-4. PubMed
  4. Minnich V, Okcuoglu A, Tarcon Y, et al. Pica in Turkey. II. Effect of clay upon iron absorption. Am J Clin Nutr 1968;21(1):78-86.
  5. O'Rourke DE, Quinn JG, Nicholson JO, Gibson HH. Geophagia during pregnancy. Obstet Gynecol 1967;29(4):581-4.
  6. Edwards CE, McDonald S, Mitchell JK, et al. Effect of clay and cornstarch intake on women and their infants. J Amer Diet Assoc 1964;44:109-15. DOI
  7. Carpenter WM. Observations on Cachexia Africana, on habits and effects of dirt eating in negro race. New Orleans Med Surg J 1844;1:146-68.
  8. Ducrotte P, Dapoigny M, Bonaz B, Siproudhis L. Symptomatic efficacy of beidellitic montmorillonite in irritable bowel syndrome: a randomized, controlled trial. Aliment Pharmacol Ther 2005;21(4):435-44. PubMed
  9. Chang FY, Lu CL, Chen CY, Luo JC. Efficacy of dioctahedral smectite in treating patients of diarrhea-predominant irritable bowel syndrome. J Gastroenterol Hepatol 2007;22(12):2266-72. PubMed
  10. Blum M, Orton C, Rose L. The effect of starch ingestion on excessive iron association, abstracted. Ann Intern Med 1968;68:1165.
  11. Ukaonu C, Hill DA, Christensen F. Hypokalemic myopathy in pregnancy caused by clay ingestion. Obstet Gynecol 2003;102(5 Pt 2):1169-71. DOI
  12. Andrews PL, Horn CC. Signals for nausea and emesis: Implications for models of upper gastrointestinal diseases. Auton Neurosci 2006;125(1-2):100-15. PubMed
  13. Wang JS, Luo H, Billam M, et al. Short-term safety evaluation of processed calcium montmorillonite clay (NovaSil) in humans. Food Addit Contam 2005;22(3):270-9. PubMed
  14. Bateson EM, Lebroy T. Clay eating by Aboriginals of the Northern Territory. Med J Aust 1978;1 Suppl 1:1-3. PubMed
  15. Delaitre B, Lemaigre G, Acar JF, et al. [Necrotizing enteritis and geophagia]. Nouv Presse Med 1976;5(28):1743-6.
  16. Sanchez A JE. Perforation of the colon due to clay ball. Arch Surg 1978;113(7):906. PubMed
  17. Prasad AS, Halsted JA, Nadimi M. Syndrome of iron deficiency anemia, hepatospelenomegaly, hypogonadism, dwarfism and geophagia. Am J Med 1961;31:532-46.
  18. Bennett A, Stryjewski G. Severe hypokalemia caused by oral and rectal administration of bentonite in a pediatric patient. Pediatr Emerg Care 2006;22(7):500-2. PubMed
  19. Guinee VF. Pica and lead poisoning. Nutr Rev 1971;29(12):267-9. PubMed
  20. Getahun H, Lambein F, Vanhoorne M, Van der Stuyft P. Neurolathyrism risk depends on type of grass pea preparation and on mixing with cereals and antioxidants. Trop Med Int Health 2005;10(2):169-78. PubMed
  21. Trivedi TH, Daga GL, Yeolekar ME. Geophagia leading to hypokalemic quadriparesis in a postpartum patient. J Assoc Physicians India 2005;53:205-7.
  22. Fredj G, Farinotti R, Salvadori C, et al. [Topical digestive drugs with a clay base. Influence on the absorption of cimetidine]. Therapie 1986;41(1):23-5.
  23. Dominy NJ, Davoust E, Minekus M. Adaptive function of soil consumption: an in vitro study modeling the human stomach and small intestine. J Exp Biol 2004;207(Pt 2):319-24.
  24. Pariente EA, De La Garoullaye G. A multicenter comparative study of a mucilage (Karaya gum + PVPP) versus clay in functional intestinal disorders. Med Chir Dig 1994;23(3):193-9.
  25. Pérez-Gaxiola G, Cuello-García CA, Florez ID, Pérez-Pico VM. Smectite for acute infectious diarrhoea in children. Cochrane Database Syst Rev. 2018;4:CD011526. PubMed
  26. Kee BK, Morris JS, Slack RS, et al. A phase II, randomized, double blind trial of calcium aluminosilicate clay versus placebo for the prevention of diarrhea in patients with metastatic colorectal cancer treated with irinotecan. Support Care Cancer. 2015;2 PubMed
  27. Mitchell NJ, Kumi J, Aleser M, et al. Short-term safety and efficacy of calcium montmorillonite clay (UPSN) in children. Am J Trop Med Hyg. 2014;91(4):777-85. PubMed
  28. Gupta M, Sachdev A, Lehl SS, Singh K. Clay impaction causing acute dysphagia. BMJ Case Rep. 2013;2013. pii: bcr2013008929. PubMed
  29. Lin JX, Fan ZY, Lin Q, et al. A comparison of dioctahedral smectite and iodine glycerin cream with topical mouth rinse in treatment of chemotherapy induced oral mucositis: a pilot study. Eur J Oncol Nurs. 2015;19(2):136-41. PubMed
  30. Lai BY, Liang N, Cao HJ, et al. Pediatric Tui Na for acute diarrhea in children under 5 years old: A systematic review and meta-analysis of randomized clinical trials. Complement Ther Med. 2018;41:10-22. PubMed
  31. Schmidt C, Oxley Oxland J, Freercks R. A rare case of hypokalaemia and hypophosphataemia secondary to geophagia. BMJ Case Rep. 2021 May 12;14(5):e239322. PubMed

See these in context on the Clay monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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