Interactions on record — worth a quick check against your medications. Based on 5 of 6 ingredients. Check your meds →
Dietary supplement

ClearPassage Licorice + Peppermint Ingredients & Drug Interactions

by Oregon's Wild Harvest

ClearPassage Licorice + Peppermint label
See full label image
Liquid Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking ClearPassage Licorice + Peppermint against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

ClearPassage Licorice + Peppermint is a dietary supplement by Oregon's Wild Harvest with 6 active ingredients. Its ingredients are commonly taken for cough and chest congestion, sore throat, bronchitis and respiratory irritation.Based on those ingredients, 2,149 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are fresh Marshmallow, fresh Licorice, Horehound. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against ClearPassage Licorice + Peppermint by Oregon's Wild Harvest

Ask about any prescription or over-the-counter medication and we check it for interactions with ClearPassage Licorice + Peppermint by Oregon's Wild Harvest — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of ClearPassage Licorice + Peppermint by Oregon's Wild Harvest

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 6 active ingredients.
  • “Biodynamic & Organic Proprietary Blend” is a proprietary blend — the label gives one combined amount (860 mg) without saying how much of each component you get.

ClearPassage Licorice + Peppermint is a 6-ingredient liquid formula. The active ingredients are mullein (used traditionally for respiratory support), yarrow, fresh marshmallow, fresh licorice, fresh western red cedar, and white horehound.

The product also contains inactive ingredients — biodynamic and organic alcohol, organic glycerin, organic peppermint flavor extract, and distilled water — which serve as carriers and preservatives in the liquid form.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: lung support and respiratory health.
  • We looked for evidence on: Bronchitis, Cough, Respiratory tract infections, Asthma, Influenza, Pneumonia — and 4 related terms.
  • The closest evidence on file: Yarrow is rated "Insufficient Reliable Evidence To Rate" for Tonsillitis (Natural Medicines).
  • Also on file: Mullein is rated "Insufficient Reliable Evidence To Rate" for Bronchitis, Asthma, Cough, Influenza, and more.
  • Also on file: Marshmallow is rated "Insufficient Reliable Evidence To Rate" for ACE inhibitor-induced cough.

The evidence we hold doesn't establish that any of these herbs work for a specific condition. Licorice is rated possibly effective for canker sores and atopic dermatitis (eczema).

For the other ingredients — mullein, yarrow, marshmallow, western red cedar, and horehound — the data shows insufficient reliable evidence to rate them for their traditional uses. If you're considering this product for a particular health concern, talk with your pharmacist or doctor about whether the evidence supports its use.

The evidence, ingredient by ingredient Mullein Yarrow Marshmallow Licorice White Horehound

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 5 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 5 of 5.
  • General safety write-ups exist for 5 of 5.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Licorice is the biggest safety concern here. The active ingredient glycyrrhizin can cause serious problems with high doses or long-term use — avoid this product during pregnancy, as licorice has been linked to harmful effects.

It's not well studied in breastfeeding either. Yarrow and horehound are traditionally believed to affect the uterus, so they're best avoided in pregnancy.

Mullein, marshmallow, and the others are generally well tolerated for short-term use, but human safety data are limited across the board. Yarrow and marshmallow should also be avoided while breastfeeding.

Topical contact with some of these plants — yarrow, mullein, and horehound — can cause skin reactions like dermatitis in some people.

Side effects, ingredient by ingredient Mullein Yarrow Marshmallow Licorice White Horehound

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 5 of the 5 matched ingredients can interact with medications — Yarrow, Mullein, Marshmallow, Licorice, White Horehound.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications; heart-rhythm medications; lithium.
  • For scale: 2,150 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your pharmacist if you're on blood thinners like warfarin, heart medications like digoxin, lithium, blood pressure drugs, diabetes medications, or certain cancer treatments — these are Moderate-severity interactions. Also check if you're taking any medication metabolized by your liver (CYP2B6, CYP2C19, or CYP3A4), sedatives like midazolam, or loop diuretics.

Mullein adds a Minor interaction with blood thinners and antiplatelet drugs.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This product is not for you if you take lithium, warfarin, digoxin, blood pressure medications, diabetes medications, or certain cancer drugs — the interactions are real and potentially serious. If you're pregnant or breastfeeding, the safety data advises against it.

If you take any prescription medication at all, use the interaction checker on this page before adding this product. Talk with your pharmacist about whether it's right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 25, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about ClearPassage Licorice + Peppermint, straight from the product label.

Brand Oregon's Wild Harvest
Barcode (UPC) 706195173535
Net contents 2 fl. Oz.; 59 mL
Market status On market
Date entered into DSLD Apr 25, 2018
DSLD ID 175636
Product type Other Combinations
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Organic, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for ClearPassage Licorice + Peppermint by Oregon's Wild Harvest, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2.5 mL
Maximum serving Sizes:
2.5 mL
Servings per container
24
UPC/BARCODE
706195173535
IngredientAmount% DV
Biodynamic & Organic Proprietary Blend860 mg--
Mullein0 NP--
Yarrow0 NP--
fresh Marshmallow0 NP--
fresh Licorice0 NP--
fresh Western Red Cedar0 NP--
Horehound0 NP--

Other ingredients: Biodynamic and organic Alcohol, organic Glycerin, organic Peppermint flavor extract, distilled Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

The tastiest and most dynamic lung support formula we make.

Since 1994

Respiratory system support

24 tasty servings

Alcohol Content: Not more than 30%

Suggested/Recommended/Usage/Directions

Suggested Use: As an herbal tonic, take 2.5 mL (approx. three half-droppers) daily before meals as needed or as directed by your healthcare professional.

Shake well.

Precautions

Do not exceed recommended dose.

Caution: Do not take if sensitive to peanuts or chickpeas.

Keep out of reach of children.

Do not take if pregnant or nursing. If taking medication consult a healthcare professional before use.

Discontinue use if unusual symptoms occur.

Formulation

Does not contain dairy, wheat, gluten, soy or corn allergens.

USDA Organic Certified Organic

Certified Organic by Oregon Tilth

Non GMO

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General

R4

FDA Statement of Identity

Herbal Supplement

Seals/Symbols

USDA Organic Certified Organic

Demeter Certified Biodynamic

OTCO

GF

Non GMO

Storage

Store upright in a cool, dry place.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

ClearPassage Licorice + Peppermint by Oregon's Wild Harvest label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

ClearPassage Licorice + Peppermint label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in ClearPassage Licorice + Peppermint by Oregon's Wild Harvest

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size2.5 mL Dosage formLiquid Servings per container24 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Biodynamic & Organic Proprietary Blend

860 mg per serving

Other (inactive) ingredients: Biodynamic and organic Alcohol, Organic Glycerin, Organic Peppermint flavor extract, Distilled Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

ClearPassage Licorice + Peppermint by Oregon's Wild Harvest Drug Interactions

Want to check YOUR meds against ClearPassage Licorice + Peppermint?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2,149Drugs
1,042 Moderate 1,107 Minor

Ingredients driving the most interactions

fresh Marshmallow 2,040
fresh Licorice 1,040
Horehound 258
Mullein 122
Yarrow 1

Individual Drug Interactions

The ingredients in ClearPassage Licorice + Peppermint interact with 2,149 drugs. Click any drug to see the details.

5 of the 6 ingredients in ClearPassage Licorice + Peppermint interact with drugs. Each result below shows which ingredient is responsible. fresh Marshmallow fresh Licorice Horehound Mullein Yarrow

Each ingredient & the kinds of drugs it affects

For each ingredient in ClearPassage Licorice + Peppermint with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

fresh Marshmallow3 drug types · 2,040 drugs

Lithium

Theoretically, due to potential diuretic effects, marshmallow might reduce excretion and increase levels of lithium.
Marshmallow is thought to have diuretic properties. To avoid lithium toxicity, the dose of lithium might need to be decreased when used with marshmallow.

Likelihood Probable Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, marshmallow flower might have antiplatelet effects.
Animal research suggests that marshmallow flower extract has antiplatelet effects. However, the root and leaf of marshmallow, not the flower, are the plant parts most commonly found in dietary supplements. Theoretically, use of marshmallow flower with anticoagulant/antiplatelet drugs can have additive effects, and might increase the risk for bleeding in some patients.

Likelihood Unlikely Evidence D
Oral Drugs

Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Marshmallow contains mucilage which can affect oral drug absorption. To avoid changes in absorption, take marshmallow 30-60 minutes after oral medications.

Likelihood Possible Evidence D
fresh Marshmallow full monograph & interactions

fresh Licorice18 drug types · 1,040 drugs

Antihypertensive Drugs

Theoretically, licorice might reduce the effects of antihypertensive drugs.
In human research, licorice increases blood pressure in a dose-dependent manner.

Likelihood Possible Evidence B
Cisplatin (Platinol-Aq)

Theoretically, licorice might reduce the effects of cisplatin.
In animal research, licorice diminished the therapeutic efficacy of cisplatin.

Likelihood Possible Evidence D
Corticosteroids

Theoretically, concomitant use of licorice and corticosteroids might increase the side effects of corticosteroids.
Case reports suggest that concomitant use of licorice and oral corticosteroids, such as hydrocortisone, can potentiate the duration of activity and increase blood levels of corticosteroids. Additionally, in one case report, a patient with neurogenic orthostatic hypertension stabilized on fludrocortisone 0.1 mg twice daily developed pseudohyperaldosteronism after recent consumption of large amounts of black licorice.

Likelihood Possible Evidence D
Cytochrome P450 2B6 (Cyp2B6) Substrates

Theoretically, licorice might increase levels of drugs metabolized by CYP2B6.
In vitro research shows that licorice extract and glabridin, a licorice constituent, inhibit CYP2B6 isoenzymes. Licorice extract from the species G. uralensis seems to inhibit CYP2B6 isoenzymes to a greater degree than G. glabra extract in vitro. Theoretically, these species of licorice might increase levels of drugs metabolized by CYP2B6; however, these interactions have not yet been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, licorice might increase levels of drugs metabolized by CYP2C19.
In vitro, licorice extracts from the species G. glabra and G. uralensis inhibit CYP2C19 isoenzymes in vitro. Theoretically, these species of licorice might increase levels of drugs metabolized by CYP2C19; however, this interaction has not yet been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C8 (Cyp2C8) Substrates

Theoretically, licorice might increase levels of drugs metabolized by CYP2C8.
In vitro, licorice extract from the species G. glabra and G. uralensis inhibits CYP2C8 isoenzymes. Theoretically, these species of licorice might increase levels of drugs metabolized by CYP2C8; however, this interaction has not yet been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, licorice might increase or decrease levels of drugs metabolized by CYP2C9.
There is conflicting evidence about the effect of licorice on CYP2C9 enzyme activity. In vitro research shows that extracts from the licorice species G. glabra and G. uralensis moderately inhibit CYP2C9 isoenzymes. However, evidence from an animal model shows that licorice extract from the species G. uralensis can induce hepatic CYP2C9 activity. Until more is known, licorice should be used cautiously in people taking CYP2C9 substrates.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, licorice might increase or decrease levels of drugs metabolized by CYP3A4.
Pharmacokinetic research shows that the licorice constituent glycyrrhizin, taken in a dosage of 150 mg orally twice daily for 14 days, modestly decreases the area under the concentration-time curve of midazolam by about 20%. Midazolam is a substrate of CYP3A4, suggesting that glycyrrhizin modestly induces CYP3A4 activity. Animal research also shows that licorice extract from the species G. uralensis induces CYP3A4 activity. However, licorice extract from G. glabra species appear to inhibit CYP3A4-induced metabolism of testosterone in vitro. It is thought that the G. glabra inhibits CYP3A4 due to its constituent glabridin, which is a moderate CYP3A4 inhibitor in vitro and not present in other licorice species. Until more is known, licorice should be used cautiously in people taking CYP3A4 substrates.

Likelihood Possible Evidence B
Digoxin (Lanoxin)

Theoretically, concomitant use of licorice with digoxin might increase the risk of cardiac toxicity.
Overuse or misuse of licorice with cardiac glycoside therapy might increase the risk of cardiac toxicity due to potassium loss.

Likelihood Possible Evidence D
Diuretic Drugs

Theoretically, concomitant use of licorice with diuretic drugs might increase the risk of hypokalemia.
Overuse of licorice might compound diuretic-induced potassium loss. In one case report, a 72-year-old male with a past medical history of hypertension, type 2 diabetes, hyperlipidemia, arrhythmia, stroke, and hepatic dysfunction was hospitalized with severe hypokalemia and uncontrolled hypertension due to pseudohyperaldosteronism. This was thought to be provoked by concomitant daily consumption of a product containing 225 mg of glycyrrhizin, a constituent of licorice, and hydrochlorothiazide 12.5 mg for 1 month.

Likelihood Possible Evidence D
Estrogens

Theoretically, licorice might increase or decrease the effects of estrogen therapy.
Theoretically, licorice might interfere with estrogen therapy due to estrogenic and anti-estrogenic effects.

Likelihood Possible Evidence D
Loop Diuretics

Theoretically, loop diuretics might increase the mineralocorticoid effects of licorice.
Theoretically, loop diuretics might enhance the mineralocorticoid effects of licorice by inhibiting the enzyme that converts cortisol to cortisone; however, bumetanide (Bumex) does not appear to have this effect.

Likelihood Possible Evidence D
Midazolam (Versed)

Theoretically, licorice might decrease levels of midazolam.
In humans, the licorice constituent glycyrrhizin appears to moderately induce the metabolism of midazolam. This is likely due to induction of cytochrome P450 3A4 by licorice. Until more is known, licorice should be used cautiously in people taking midazolam.

Likelihood Possible Evidence B
P-Glycoprotein Substrates

Theoretically, licorice might decrease the absorption of P-glycoprotein substrates.
In vitro research shows that licorice can increase P-glycoprotein activity.

Likelihood Possible Evidence D
Paclitaxel (Abraxane, Onxol)

Theoretically, licorice might decrease plasma levels and clinical effects of paclitaxel.
Multiple doses of licorice taken concomitantly with paclitaxel might reduce the effectiveness of paclitaxel. Animal research shows that licorice 3 grams/kg given orally for 14 days before intravenous administration of paclitaxel decreases the exposure to paclitaxel and increases its clearance. Theoretically, this occurs because licorice induces cytochrome P450 3A4 enzymes, which metabolize paclitaxel. Notably, a single dose of licorice did not affect exposure or clearance of paclitaxel.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, licorice might decrease plasma levels and clinical effects of warfarin.
Licorice seems to increase metabolism and decrease levels of warfarin in animal models. This is likely due to induction of cytochrome P450 2C9 (CYP2C9) metabolism by licorice. Advise patients taking warfarin to avoid taking licorice.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, licorice might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that licorice induces CYP1A2 enzymes.

Likelihood Possible Evidence D
Methotrexate (Trexall, Others)

Theoretically, licorice might increase levels of methotrexate.
Animal research suggests that intravenous administration of glycyrrhizin, a licorice constituent, and high-dose methotrexate may delay methotrexate excretion and increase systemic exposure, leading to transient elevations in liver enzymes and total bilirubin. This interaction has not yet been reported in humans.

Likelihood Unlikely Evidence D
fresh Licorice full monograph & interactions

Horehound2 drug types · 258 drugs

Antidiabetes Drugs

Evidence from animal research suggests that white horehound might lower blood glucose. However, preliminary clinical research suggests that white horehound only slightly lowers blood glucose when taken in combination with antidiabetic agents, suggesting that the effect may not be clinically significant. Until more is known, use with caution. Theoretically, white horehound may have additive effects when used by patients taking antidiabetic drugs. The dose of diabetes medications might need to be adjusted. Some antidiabetes drugs include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, metformin (Glucophage), pioglitazone (Actos), rosiglitazone (Avandia), and others.

Likelihood Possible Evidence B
Antihypertensive Drugs

Evidence from animal research suggests that taking white horehound extract lowers blood pressure. Theoretically, taking white horehound with antihypertensive drugs might enhance therapeutic effects and increase the risk of hypotension. Some antihypertensive drugs include captopril (Capoten), enalapril (Vasotec), losartan (Cozaar), valsartan (Diovan), diltiazem (Cardizem), Amlodipine (Norvasc), hydrochlorothiazide (HydroDiuril), furosemide (Lasix), and many others.

Likelihood Possible Evidence D
Horehound full monograph & interactions

Mullein1 drug type · 122 drugs

Anticoagulant/Antiplatelet Drugs

Lab tests on extracts from different parts of common and dense-flowered mullein plants show that they do have some blood-thinning effects, as they increase the time it takes for blood to clot. This is likely due to at least one of the known constituents of muellein, triterpenoid saponins. However, the effects appear to be mild and results have been inconsistent. Extracts from different plant parts have been show to have varying anticoagulant strengths, with water-based ones being more potent than alcohol-based extracts.

Likelihood Unlikely Evidence A
Mullein full monograph & interactions

Yarrow1 drug type · 1 drug

Lithium

Theoretically, taking yarrow with lithium might increase the levels and adverse effects of lithium.
Animal research shows that yarrow has diuretic activity. Theoretically, due to these potential diuretic effects, yarrow might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
Yarrow full monograph & interactions
The maker

Brand information

Manufacturer and brand details for ClearPassage Licorice + Peppermint, from the product label.

Oregon's Wild Harvest

See all Oregon's Wild Harvest products
Name
Oregon's Wild Harvest
Street Address
1601 NE Hemlock Ave.
City
Redmond
State
OR
ZipCode
97756
Phone Number
1-800-316-6869
Web Address
oregonswildharvest.com
Pharmacist Counseling Corner

ClearPassage Licorice + Peppermint by Oregon's Wild Harvest: Common Questions

Does ClearPassage Licorice + Peppermint by Oregon's Wild Harvest interact with any medications?
Yes. Based on its ingredients, ClearPassage Licorice + Peppermint has a known interaction with 2,149 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
ClearPassage Licorice + Peppermint contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
No. Licorice is unsafe in pregnancy and linked to harmful effects. Yarrow and horehound are likely unsafe in pregnancy because they're traditionally believed to affect the uterus. There isn't enough safety data to recommend any of these herbs while breastfeeding. Talk with your doctor or pharmacist for personalized advice.
What is licorice supposed to do in this product?
Licorice is possibly effective for canker sores and atopic dermatitis (eczema) according to the evidence we hold. That said, it's the ingredient with the most drug interactions in this formula, so it's important to check your medications first.
Does this product actually work for coughs or bronchitis?
The data we have doesn't establish that mullein or the other herbs in this product work for coughs or bronchitis — the evidence is insufficient to rate them for those uses. If you're considering it for respiratory symptoms, ask your pharmacist whether the available evidence supports it.
What are the inactive ingredients, and are there fillers?
The inactive ingredients are biodynamic and organic alcohol, organic glycerin, organic peppermint flavor extract, and distilled water. These serve as carriers and preservatives in the liquid form — they're standard in herbal liquids and not "fillers" in a problematic sense.
Can side effects happen with this product?
Licorice can cause headache, nausea, and vomiting at normal doses, and more serious effects with high doses or long-term use. Yarrow may cause dermatitis or, in rare cases, allergic reactions. Horehound may cause nausea, dry mouth, loss of appetite, or dizziness in some people. Topical contact with yarrow, mullein, or horehound can cause skin reactions.
What's the peppermint in the name for?
The product contains organic peppermint flavor extract as an inactive ingredient — it flavors the liquid. Peppermint itself isn't listed as an active ingredient in this formula.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if ClearPassage Licorice + Peppermint is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

ClearPassage Licorice + Peppermint label
Go deeper

The Full Monographs Behind ClearPassage Licorice + Peppermint’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Mullein

Interacts with 122 drugs

Mullein is a traditional herbal remedy most often used as a tea or syrup to soothe coughs, sore throats, and respiratory irritation. High-quality human studies are lacking, so its benefits a...

Read the full Mullein monograph → Herb & supplement monograph

Yarrow

Interacts with 1 drug

Yarrow is a traditional herb long used for wounds, digestive complaints, and colds, but high-quality human studies are very limited, so its benefits are not well proven. It is generally used...

Read the full Yarrow monograph → Herb & supplement monograph

Marshmallow

Interacts with 2,040 drugs

Marshmallow root is a traditional herb rich in soothing, gel-like fibers called mucilage, which is why it has long been used for coughs, sore throats, and stomach irritation. Evidence for th...

Read the full Marshmallow monograph → Herb & supplement monograph

Licorice

Interacts with 1,040 drugs

Licorice root is a traditional remedy used for sore throats, coughs, and digestive complaints, but solid human evidence is limited for most uses. Regular licorice contains glycyrrhizin, whic...

Read the full Licorice monograph → Herb & supplement monograph

White Horehound

Interacts with 258 drugs

White horehound is a traditional bitter herb used mainly for coughs, sore throats, and mild digestive complaints, and it is a common flavoring in old-fashioned cough drops. Solid human evide...

Read the full White Horehound monograph →
Sources

Sources & How We Checked

ClearPassage Licorice + Peppermint's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 115 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Mullein 2 references
  1. Castro AI, Carmona JB, Gonzales FG, Nestar OB. Occupational airborne dermatitis from gordolobo (Verbascum densiflorum). Contact Dermatitis 2006;55(5):301.
  2. Flores Echaiz C, Al Ali A, Cao AQ, Sasseville D. Simultaneous contact dermatitis caused by Asteraceae and Verbascum thapsus. Contact Dermatitis 2017;76(5):316-8.

See these in context on the Mullein monograph →

Yarrow 8 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Uter, W., Nohle, M., Randerath, B., and Schwanitz, H. J. Occupational contact urticaria and late-phase bronchial asthma caused by compositae pollen in a florist. Am J Contact Dermat. 2001;12(3):182-184. DOI
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Marshmallow 5 references
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White Horehound 8 references
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