Coenzyme Q-10 400 mg Ingredients & Drug Interactions
by Kroger
What is this page for?
First and foremost: checking Coenzyme Q-10 400 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Coenzyme Q-10 400 mg is a dietary supplement by Kroger with 1 active ingredient. Its ingredients are commonly taken for heart health, statin-related muscle aches, migraine prevention.Based on those ingredients, 198 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Coenzyme Q-10. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Coenzyme Q-10 400 mg by Kroger
Ask about any prescription or over-the-counter medication and we check it for interactions with Coenzyme Q-10 400 mg by Kroger — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Coenzyme Q-10 400 mg by Kroger
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: coenzyme Q-10 at 400 mg per softgel. Coenzyme Q-10 is a compound your body makes naturally and stores in cells to help with energy production.
The capsule also contains inactive ingredients — rice bran oil, gelatin, glycerin, and minor additives — that help deliver the active ingredient.
Does it work?
Moderate evidence
Coenzyme Q-10 is likely effective for treating coenzyme Q-10 deficiency. It's also possibly effective for fibromyalgia, migraine headache, congestive heart failure, and diabetic neuropathy, based on the evidence we have on file.
That said, research results have been mixed for some of these uses, so talk with your doctor about whether it's right for your specific situation.
How safe is it?
Well-documented data
Coenzyme Q-10 is generally well tolerated by most adults when used as directed. In clinical studies, no serious adverse effects have been reported.
Minor gastrointestinal side effects — such as appetite suppression, diarrhea, heartburn, nausea, or vomiting — occur in less than 1% of people; dividing daily doses above 100 mg may help minimize these. Headache, dizziness, and insomnia have been reported rarely.
Skin itching and allergic rash have also been reported in a small number of people. Pregnancy safety data is not on file for coenzyme Q-10; safety while breastfeeding has not been well studied, so check with your doctor before use if you are nursing or planning to become pregnant.
Meds to double-check
Moderate interaction found
Before you take Kroger's Coenzyme Q-10, double-check any blood thinners you take, especially warfarin (Coumadin) — coenzyme Q-10 may weaken its effect. If you're on chemotherapy drugs that work by creating free radicals, such as alkylating agents like cyclophosphamide, discuss this with your oncologist first.
Blood pressure medications are worth a conversation with your doctor as well, since coenzyme Q-10 might add to their effect.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This supplement may help if you have a coenzyme Q-10 deficiency or certain conditions like migraines or heart failure, but it's not right for everyone. If you take warfarin, chemotherapy drugs, or blood pressure medications, talk to your pharmacist before starting — coenzyme Q-10 can affect how these work.
A quick medication check on this page will tell you if your prescriptions are a concern.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2017.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Coenzyme Q-10 400 mg, straight from the product label.
| Brand | Kroger |
|---|---|
| Barcode (UPC) | 041260349287 |
| Net contents | 30 Softgel(s) |
| Market status | On market |
| Date entered into DSLD | Jul 25, 2017 |
| DSLD ID | 75939 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Softgel Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Coenzyme Q-10 400 mg by Kroger, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 10 Calorie(s) | -- |
| Total Fat | 1 Gram(s) | 1% |
| Coenzyme Q-10 | 400 mg | -- |
Other ingredients: Rice Bran Oil, Gelatin, Glycerin, Contains less than 2% of:
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Actual size
Heart support
Coenzyme Q-10's antioxidant properties help fight cell-damaging free radicals in the body. Coenzyme Q-10 can support heart health.
General
Prod. No. 13335 B67896 03D 14-10195QKS
FDA Statement of Identity
Dietary Supplement
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Formula
Coenzyme Q-10 is an ingredient that can be found in almost every cell in the body.
Contains: Soy.
Precautions
Contains: Soy.
Warning: If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use.
Discontinue use and consult your doctor if any adverse reactions occur.
Keep out of reach of children.
Tamper Resistant: Do not use if seal under cap is broken or missing.
Formulation
Gluten free
Suggested/Recommended/Usage/Directions
Suggested Use: Take one (1) softgel daily with a full glass of water, preferably after a meal.
Storage
Store at room temperature, tightly closed.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Coenzyme Q-10 400 mg by Kroger label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Coenzyme Q-10 400 mg by Kroger
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container30 Amounts shown are per serving.
Coenzyme Q-10
Interacts with198 drugs
CoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated...
Coenzyme Q-10 monograph & interactionsOther (inactive) ingredients: Rice Bran Oil, Gelatin, Glycerin, Contains less than 2% of:. These complete the product’s ingredient list but are not active constituents.
Coenzyme Q-10 400 mg by Kroger Drug Interactions
HelloPharmacist Interaction Report
Kroger's Coenzyme Q-10 400 mg does interact with several important medications.
The most serious concern is with warfarin (Coumadin), a blood thinner — coenzyme Q-10 is chemically similar to vitamin K and may reduce how well warfarin works to prevent clots. Four cases of decreased warfarin effectiveness linked to coenzyme Q-10 have been reported.
Read the full breakdown — every affected drug type, severity by severity
Coenzyme Q-10 may also interfere with certain chemotherapy drugs, particularly alkylating agents like cyclophosphamide. Because coenzyme Q-10 is an antioxidant, it theoretically could reduce the activity of chemotherapy that relies on generating free radicals to kill cancer cells.
You may also want to discuss this supplement with your doctor if you take blood pressure medications — coenzyme Q-10 might add to their effect, though research on this is mixed.
Alone, coenzyme Q-10 is the only active ingredient here. Altogether, these interactions span 198 individual medications.
Use the medication checker on this page to confirm whether any of your prescriptions are affected before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Coenzyme Q-10 400 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Coenzyme Q-10 400 mg interact with 198 drugs. Click any drug to see the details.
1 of the 1 ingredient in Coenzyme Q-10 400 mg interact with drugs. Each result below shows which ingredient is responsible. Coenzyme Q-10
AmilorideAmilamont, Midamor
How Amiloride interacts with Coenzyme Q-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Amiloride interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with Coenzyme Q-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Amiloride, Hydrochlorothiazide interactionAmlodipineNorliqva
How Amlodipine interacts with Coenzyme Q-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Amlodipine interactionAmlodipine BenzoateKaterzia
How Amlodipine Benzoate interacts with Coenzyme Q-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Amlodipine Benzoate interactionAmlodipine BesilateIstin
How Amlodipine Besilate interacts with Coenzyme Q-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Amlodipine Besilate interactionAmlodipine BesylateNorvasc
How Amlodipine Besylate interacts with Coenzyme Q-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Amlodipine Besylate interactionAmlodipine Besylate, BenazeprilLotrel
How Amlodipine Besylate, Benazepril interacts with Coenzyme Q-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Amlodipine Besylate, Benazepril interactionAmlodipine, CelecoxibConsensi
How Amlodipine, Celecoxib interacts with Coenzyme Q-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Amlodipine, Celecoxib interactionAmmonium ChlorideAmmonium Chloride
How Ammonium Chloride interacts with Coenzyme Q-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Ammonium Chloride interactionAprocitentanTryvio
How Aprocitentan interacts with Coenzyme Q-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Aprocitentan interactionAtenololAtenix, Tenormin
How Atenolol interacts with Coenzyme Q-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Atenolol interactionAtenolol, ChlortalidoneAtenixCo, Tenoret 50, Totaretic
How Atenolol, Chlortalidone interacts with Coenzyme Q-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Atenolol, Chlortalidone interactionAtenolol, ChlorthalidoneTenoretic
How Atenolol, Chlorthalidone interacts with Coenzyme Q-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Atenolol, Chlorthalidone interactionAzilsartanEdarbi
How Azilsartan interacts with Coenzyme Q-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Azilsartan interactionAzilsartan, ChlorthalidoneEdarbyclor
How Azilsartan, Chlorthalidone interacts with Coenzyme Q-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Azilsartan, Chlorthalidone interactionBenazeprilLotensin
How Benazepril interacts with Coenzyme Q-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Benazepril interactionBenazepril, HydrochlorothiazideLotensin HCT
How Benazepril, Hydrochlorothiazide interacts with Coenzyme Q-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Benazepril, Hydrochlorothiazide interactionBendroflumethiazideAprinox, Naturetin, Neo-NaClex
How Bendroflumethiazide interacts with Coenzyme Q-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Bendroflumethiazide interactionBendroflumethiazide, NadololCorzide
How Bendroflumethiazide, Nadolol interacts with Coenzyme Q-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Bendroflumethiazide, Nadolol interactionBendroflumethiazide, Rauwolfia SerpentinaRauzide
How Bendroflumethiazide, Rauwolfia Serpentina interacts with Coenzyme Q-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Bendroflumethiazide, Rauwolfia Serpentina interactionBenzthiazideExna
How Benzthiazide interacts with Coenzyme Q-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Benzthiazide interactionBetaxololBetoptic, Kerlone
How Betaxolol interacts with Coenzyme Q-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Betaxolol interactionBisoprololZebeta
How Bisoprolol interacts with Coenzyme Q-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Bisoprolol interactionBisoprolol, HydrochlorothiazideZiac
How Bisoprolol, Hydrochlorothiazide interacts with Coenzyme Q-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Bisoprolol, Hydrochlorothiazide interactionBosentanTracleer
How Bosentan interacts with Coenzyme Q-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Bosentan interactionBumetanideBurinex
How Bumetanide interacts with Coenzyme Q-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Bumetanide interactionBumetanide (iv)Bumex
How Bumetanide (iv) interacts with Coenzyme Q-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Bumetanide (iv) interactionBumetanide (oral)Bumex
How Bumetanide (oral) interacts with Coenzyme Q-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Bumetanide (oral) interactionCandesartan CilexetilAmias, Atacand
How Candesartan Cilexetil interacts with Coenzyme Q-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Candesartan Cilexetil interactionCandesartan Cilexetil, HydrochlorothiazideAtacand HCT
How Candesartan Cilexetil, Hydrochlorothiazide interacts with Coenzyme Q-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Candesartan Cilexetil, Hydrochlorothiazide interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Coenzyme Q-10 400 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Coenzyme Q-10
Alkylating Agents
Coenzyme Q10 has antioxidant effects. Theoretically, this may reduce the activity of chemotherapy drugs that generate free radicals.
Theoretically, antioxidants such as coenzyme Q10 might protect tumor cells from chemotherapeutic agents that work by inducing oxidative stress, such as alkylating agents (e.g., cyclophosphamide) and radiation therapy. The clinical importance of this interaction is unknown.
Warfarin (Coumadin)
Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Concomitant use of coenzyme Q10 and warfarin might reduce the anticoagulant effects of warfarin. Four cases of decreased warfarin efficacy thought to be due to coenzyme Q10 have been reported. However, there is some preliminary clinical research that suggests coenzyme Q10 might not significantly decrease the effects of warfarin in patients who have a stable INR.
Antihypertensive Drugs
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Some clinical research shows that coenzyme Q10 can significantly lower blood pressure, although other studies have shown conflicting results.
Brand information
Manufacturer and brand details for Coenzyme Q-10 400 mg, from the product label.
Kroger
See all Kroger products- Name
- The Kroger Co.
- City
- Cincinnati
- State
- OH
- ZipCode
- 45202
- Phone Number
- 800-632-6900
- Web Address
- www.kroger.com
Coenzyme Q-10 400 mg by Kroger: Common Questions
Does Coenzyme Q-10 400 mg by Kroger interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Does coenzyme Q-10 really work?
What side effects might I get?
Is it safe to take if I'm breastfeeding?
What is coenzyme Q-10 and why do I need it?
Will this interact with my blood pressure medication?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Coenzyme Q-10 400 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Coenzyme Q-10 400 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Coenzyme Q-10 400 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 40 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Coenzyme Q10 40 references
- Kamikawa T, Kobayashi A, Yamashita T, et al. Effects of coenzyme Q10 on exercise tolerance in chronic stable angina pectoris. Am J Cardiol 1985;56:247-51. PubMed
- Langsjoen P, Willis R, Folkers K. Treatment of essential hypertension with coenzyme Q10. Mol Aspects Med 1994;S265-72. PubMed
- Spigset O. Reduced effect of warfarin caused by ubidecarenone. Lancet 1994;334:1372-3. PubMed
- Singh RB, Niaz MA, Rastogi SS, et al. Effect of hydrosoluble coenzyme Q10 on blood pressures and insulin resistance in hypertensive patients with coronary artery disease. J Hum Hypertens 1999;13:203-8. PubMed
- Portakal O, Ozkaya O, Erden Inal M, et al. Coenzyme Q10 concentrations and antioxidant status in tissues of breast cancer patients. Clin Biochem 2000;33:279-84. PubMed
- Lund EL, Quistorff B, Spang-Thomsen M, Kristjansen PE. Effect of radiation therapy on small-cell lung cancer is reduced by ubiquinone intake. Folia Microbiol (Praha) 1998;43:505-6. PubMed
- Langsjoen PH, Langsjoen PH, Folkers K. Long-term efficacy and safety of coenzyme Q10 therapy for idiopathic dilated cardiomyopathy. Am J Cardiol 1990;65:521-3. PubMed
- Heck AM, DeWitt BA, Lukes AL. Potential interactions between alternative therapies and warfarin. Am J Health Syst Pharm 2000;57:1221-7. DOI
- Landbo C, Almdal TP. [Interaction between warfarin and coenzyme Q10]. Ugeskr Laeger 1998;160:3226-7.
- Baggio E, Gandini R, Plauncher AC, et al. Italian multicenter study on the safety and efficacy of coenzyme Q10 as adjunctive therapy in heart failure. CoQ10 Drug Surveillance Investigators. Mol Aspects Med 1994;15 Suppl:S287-94. PubMed
- Burke BE, Neuenschwander R, Olson RD. Randomized, double-blind, placebo-controlled trial of coenzyme Q10 in isolated systolic hypertension. South Med J 2001;94:1112-7. PubMed
- The Huntington Study Group. A randomized, placebo-controlled trial of coenzyme Q10 and remacemide in Huntington's disease. Neurology 2001;57:397-404.
- Hodgson JM, Watts GF, Playford DA, et al. Coenzyme Q10 improves blood pressure and glycaemic control: a controlled trial in subjects with type 2 diabetes. Eur J Clin Nutr 2002;56:1137-42. PubMed
- Singh RB, Neki NS, Kartikey K, et al. Effect of coenzyme Q10 on risk of atherosclerosis in patients with recent myocardial infarction. Mol Cell Biochem 2003;246:75-82. DOI
- Porterfield LM. Why did the response to warfarin change? RN 2000;63:107.
- Sandor PS, Di Clemente L, Coppola G, et al. Efficacy of coenzyme Q10 in migraine prophylaxis: A randomized controlled trial. Neurology 2005;64:713-5. PubMed
- Engelsen J, Nielsen JD, Winther K. Effect of coenzyme Q10 and Ginkgo biloba on warfarin dosage in stable, long-term warfarin treated outpatients. A randomised, double blind, placebo-crossover trial. Thromb Haemost 2002;87:1075-6. DOI
- Berman M, Erman A, Ben-Gal T, et al. Coenzyme Q10 in patients with end-stage heart failure awaiting cardiac transplantation: a randomized, placebo-controlled study. Clin Cardiol 2004;27:295–9. PubMed
- Storch A, Jost WH, Vieregge P, et al. Randomized, double-blind, placebo-controlled trial on symptomatic effects of coenzyme Q10 in Parkinson disease. Arch Neurol 2007;64:938-44. DOI
- Digiesi V, Cantini F, Oradei A, et al. Coenzyme Q10 in essential hypertension. Mol Aspects Med 1994;15 Suppl:s257-63. PubMed
- Yamagami T, Takagi M, Akagami H, et al. Effect of coenzyme Q10 on essential hypertension, a double blind controlled study. In: Folkers KA, Yamamura Y, eds. Biomedical and Clinical Aspects of Coenzyme Q, Vol. 5. Amsterdam: Elsevier Science Publications, 19
- Ho MJ, Bellusci A, Wright JM. Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension (review). Cochrane Database Syst Rev 2009;(4):CD007435. PubMed
- Rosenfeldt, F. L., Haas, S. J., Krum, H., Hadj, A., Ng, K., Leong, J. Y., and Watts, G. F. Coenzyme Q10 in the treatment of hypertension: a meta-analysis of the clinical trials. J Hum.Hypertens. 2007;21(4):297-306. PubMed
- Stamelou, M., Reuss, A., Pilatus, U., Magerkurth, J., Niklowitz, P., Eggert, K. M., Krisp, A., Menke, T., Schade-Brittinger, C., Oertel, W. H., and Hoglinger, G. U. Short-term effects of coenzyme Q10 in progressive supranuclear palsy: a randomized, place DOI
- Keogh A, Fenton S, Leslie C, et al. Randomised double-blind, placebo-controlled trial of coenzyme Q, therapy in class II and III systolic heart failure. Heart Lung Circ. 2003;12:135-41.
- Gane, E. J., Weilert, F., Orr, D. W., Keogh, G. F., Gibson, M., Lockhart, M. M., Frampton, C. M., Taylor, K. M., Smith, R. A., and Murphy, M. P. The mitochondria-targeted anti-oxidant mitoquinone decreases liver damage in a phase II study of hepatitis C
- Lynch, D. R., Perlman, S. L., and Meier, T. A phase 3, double-blind, placebo-controlled trial of idebenone in friedreich ataxia. Arch Neurol. 2010;67(8):941-947. PubMed
- Young, J. M., Florkowski, C. M., Molyneux, S. L., McEwan, R. G., Frampton, C. M., Nicholls, M. G., Scott, R. S., and George, P. M. A randomized, double-blind, placebo-controlled crossover study of coenzyme Q10 therapy in hypertensive patients with the me
- Ishiyama, T., Morita, Y., Toyama, S., Yamagami, T., and Tsukamoto, N. A clinical study of the effect of coenzyme Q on congestive heart failure. Jpn.Heart J 1976;17(1):32-42. PubMed
- Matthews, P. M., Ford, B., Dandurand, R. J., Eidelman, D. H., O'Connor, D., Sherwin, A., Karpati, G., Andermann, F., and Arnold, D. L. Coenzyme Q10 with multiple vitamins is generally ineffective in treatment of mitochondrial disease. Neurology 1993;43(5
- Malm, C., Svensson, M., Sjoberg, B., Ekblom, B., and Sjodin, B. Supplementation with ubiquinone-10 causes cellular damage during intense exercise. Acta Physiol Scand. 1996;157(4):511-512. PubMed
- Singh, R. B., Wander, G. S., Rastogi, A., Shukla, P. K., Mittal, A., Sharma, J. P., Mehrotra, S. K., Kapoor, R., and Chopra, R. K. Randomized, double-blind placebo-controlled trial of coenzyme Q10 in patients with acute myocardial infarction. Cardiovasc. PubMed
- Digiesi V, Cantini F, and Brodbeck B. Effect of coenzyme Q10 on essential arterial hypertension. Current Therapeutic Research 1990;47(5):841-845.
- Parkinson Study Group QE3 Investigators, Beal MF, Oakes D, et al. A randomized clinical trial of high-dosage coenzyme Q10 in early Parkinson disease: no evidence of benefit. JAMA Neurol. 2014;71(5):543-52.
- Alehagen U, Johansson P, Bjornstedt M, et al. Cardiovascular mortality and N-terminal-proBNP reduced after combined selenium and coenzyme Q10 supplementation: A 5-year prospective randomized double-blind placebo-controlled trial among elderly Swedish citi
- Ho MJ, Li EC, Wright JM. Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension. Cochrane Database Syst Rev. 2016 Mar 3;3:CD007435. doi: 10.1002/14651858.CD007435.pub3. PubMed
- Tabrizi R, Akbari M, Sharifi N, Lankarani KB, Moosazadeh M, Kolahdooz F, et al. The effects of coenzyme Q10 supplementation on blood pressures among patients with metabolic diseases: a systematic review and meta-analysis of randomized controlled trials. PubMed
- Tsai IC, Hsu CW, Chang CH, Tseng PT, Chang KV. Effectiveness of coenzyme Q10 supplementation for reducing fatigue: A systematic review and meta-analysis of randomized controlled trials. Front Pharmacol 2022;13:883251. PubMed
- Yaghini O, Hoseini N, Ghazavi MR, et al. A comparative study on the efficacy of coenzyme Q10 and amitriptyline in the prophylactic treatment of migraine headaches in children: A randomized controlled trial. Adv Biomed Res 2022;11:43. PubMed
- Hansen KS, Mogensen TH, Agergaard J, et al. High-dose coenzyme Q10 therapy versus placebo in patients with post COVID-19 condition: A randomized, phase 2, crossover trial. Lancet Reg Health Eur 2022. PubMed
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